{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,26]],"date-time":"2025-10-26T13:53:49Z","timestamp":1761486829487},"reference-count":0,"publisher":"Cambridge University Press (CUP)","issue":"4","license":[{"start":{"date-parts":[[1999,4,1]],"date-time":"1999-04-01T00:00:00Z","timestamp":922924800000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Parasitology"],"published-print":{"date-parts":[[1999,4]]},"abstract":"<jats:p>We present the first parasitological, molecular and longitudinal\n analysis of an isolated outbreak of malaria. This outbreak \noccurred on Santiago Island (Republic of Cabo Verde), a region where malaria\n is hypoendemic and controlled, and thus \nthe population is considered non-immune. Blood samples were collected from\n the inhabitants over 1 month and during \ncross-sectional surveys in the following year. The presence and nature\n of the parasites was determined by PCR. <jats:italic>Plasmodium \nfalciparum<\/jats:italic> was the only species detected. Genetic analysis revealed\n that the circulating parasites were genetically \nhomogeneous, and probably clonal. Gametocytes were found throughout this\n period. Our data suggest that this represented a \nfocal outbreak, resulting in the infection of at least 40% of the villagers\n with a clonal parasite line. Thus, <jats:italic>P. falciparum<\/jats:italic> \ninfections can persist for at least 1 year in a substantial proportion\n (10%) of the hosts. Implications for malaria control \nand the interpretation of epidemiological data are discussed.<\/jats:p>","DOI":"10.1017\/s0031182099003972","type":"journal-article","created":{"date-parts":[[2002,7,27]],"date-time":"2002-07-27T13:30:22Z","timestamp":1027776622000},"page":"347-355","source":"Crossref","is-referenced-by-count":40,"title":["A clonal <i>Plasmodium falciparum<\/i> population in an isolated\n \noutbreak of malaria in the Republic of Cabo Verde"],"prefix":"10.1017","volume":"118","author":[{"given":"A. P.","family":"AREZ","sequence":"first","affiliation":[]},{"given":"G.","family":"SNOUNOU","sequence":"additional","affiliation":[]},{"given":"J.","family":"PINTO","sequence":"additional","affiliation":[]},{"given":"C. A.","family":"SOUSA","sequence":"additional","affiliation":[]},{"given":"D.","family":"MODIANO","sequence":"additional","affiliation":[]},{"given":"H.","family":"RIBEIRO","sequence":"additional","affiliation":[]},{"given":"A. S.","family":"FRANCO","sequence":"additional","affiliation":[]},{"given":"J.","family":"ALVES","sequence":"additional","affiliation":[]},{"given":"V. E.","family":"do ROSARIO","sequence":"additional","affiliation":[]}],"member":"56","published-online":{"date-parts":[[1999,4,1]]},"container-title":["Parasitology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S0031182099003972","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,4,7]],"date-time":"2019-04-07T20:25:45Z","timestamp":1554668745000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S0031182099003972\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1999,4]]},"references-count":0,"journal-issue":{"issue":"4","published-print":{"date-parts":[[1999,4]]}},"alternative-id":["S0031182099003972"],"URL":"https:\/\/doi.org\/10.1017\/s0031182099003972","relation":{},"ISSN":["0031-1820","1469-8161"],"issn-type":[{"value":"0031-1820","type":"print"},{"value":"1469-8161","type":"electronic"}],"subject":[],"published":{"date-parts":[[1999,4]]}}}