{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,2]],"date-time":"2025-10-02T13:34:49Z","timestamp":1759412089255,"version":"3.40.5"},"reference-count":22,"publisher":"Cambridge University Press (CUP)","issue":"5","license":[{"start":{"date-parts":[[2018,2,20]],"date-time":"2018-02-20T00:00:00Z","timestamp":1519084800000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":["www.cambridge.org"],"crossmark-restriction":true},"short-container-title":["Epidemiol. Infect."],"published-print":{"date-parts":[[2018,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>This study evaluated the impact of maternal vaccination against rubella on the levels of specific rubella IgG (rIgG) in 198 newborn cord sera samples. Detailed maternal vaccination data were available. Specific rIgG was measured using a commercial enzyme immunoassay. Most mothers (78.8%) had been vaccinated against rubella at least once in their lives. In 15 (7.6%) cord sera samples, the concentration of specific rIgG was below 11 IU\/ml, which was classified as seronegative. Statistical analysis using multiple logistic regression (<jats:italic>n<\/jats:italic> = 198) showed that newborns of mothers born between 1986 and 1995, and those born to unvaccinated mothers, were more likely to be seronegative (odds ratio (ORs) 5.2 and 4.9, respectively, adjusted for sex and gestational age). For vaccinated mothers (<jats:italic>n<\/jats:italic> = 156), those born between 1986 and 1995 were more likely to have seronegative newborns (OR 11.5 adjusting for sex, gestational age and time since last vaccination). Mothers of the 15 (7.6%) seronegative newborns might have been susceptible to rubella during pregnancy. Checking the vaccination status therefore recommended.<\/jats:p>","DOI":"10.1017\/s0950268818000237","type":"journal-article","created":{"date-parts":[[2018,2,20]],"date-time":"2018-02-20T11:15:52Z","timestamp":1519125352000},"page":"600-605","update-policy":"https:\/\/doi.org\/10.1017\/policypage","source":"Crossref","is-referenced-by-count":2,"title":["Rubella antibodies in cord blood sera in Portugal: association with maternal age and vaccination status"],"prefix":"10.1017","volume":"146","author":[{"given":"J.","family":"Frade","sequence":"first","affiliation":[]},{"given":"C.","family":"Nunes","sequence":"additional","affiliation":[]},{"given":"J. R.","family":"Mesquita","sequence":"additional","affiliation":[]},{"given":"M.","family":"S\u00e3o Jos\u00e9 Nascimento","sequence":"additional","affiliation":[]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0030-3346","authenticated-orcid":false,"given":"G.","family":"Gon\u00e7alves","sequence":"additional","affiliation":[]}],"member":"56","published-online":{"date-parts":[[2018,2,20]]},"reference":[{"key":"S0950268818000237_ref6","unstructured":"Portuguese Health Ministry. Direc\u00e7\u00e3o Geral dos Cuidados de Sa\u00fade Prim\u00e1rios. Programa de vacina\u00e7\u00e3o contra a parotidite epid\u00e9mica. Norma de Servi\u00e7o No 5\/DTP, 12\/02\/1987."},{"key":"S0950268818000237_ref14","doi-asserted-by":"publisher","DOI":"10.1016\/S0264-410X(01)00435-2"},{"key":"S0950268818000237_ref3","first-page":"707","volume-title":"With Assistance of Offit PA. 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Avalia\u00e7\u00e3o do Programa Nacional de Vacina\u00e7\u00e3o e melhoria do seu custo-Efectividade: 2\u00b0 Inqu\u00e9rito Serol\u00f3gico Nacional Portugal Continental 2001\u20132002","author":"Palminha","year":"2004"},{"key":"S0950268818000237_ref5","doi-asserted-by":"publisher","DOI":"10.1017\/S0950268816001655"},{"key":"S0950268818000237_ref7","unstructured":"Portuguese Health Ministry. Direc\u00e7\u00e3o Geral dos Cuidados de Sa\u00fade Prim\u00e1rios. Normas de vacina\u00e7\u00e3o do programa nacional de vacina\u00e7\u00e3o. Circular Normativa No 10\/DTF, 04\/09\/1990."},{"key":"S0950268818000237_ref11","unstructured":"Meeting of the European Regional Verification Commission for Measles and Rubella Elimination (RVC). 26\u201329 October 2015, Copenhagen, Denmark. WHO. Regional Office for Europe, 2015. Available at http:\/\/www.euro.who.int\/__data\/assets\/pdf_file\/0011\/304958\/4th-RVC-meeting-report.pdf (Accessed January 2017)."},{"key":"S0950268818000237_ref13","doi-asserted-by":"publisher","DOI":"10.1586\/14760584.2013.814847"},{"key":"S0950268818000237_ref15","doi-asserted-by":"publisher","DOI":"10.1016\/S0020-7292(02)00442-3"},{"key":"S0950268818000237_ref16","doi-asserted-by":"publisher","DOI":"10.1001\/archpedi.1979.02130120032005"},{"key":"S0950268818000237_ref17","doi-asserted-by":"publisher","DOI":"10.1097\/00006454-200404000-00019"},{"key":"S0950268818000237_ref20","doi-asserted-by":"publisher","DOI":"10.1086\/605410"},{"key":"S0950268818000237_ref21","doi-asserted-by":"publisher","DOI":"10.1007\/BF02561529"},{"key":"S0950268818000237_ref2","first-page":"60","article-title":"Control of rubella and congenital rubella syndrome (CRS) in developing countries, part 2: vaccination against rubella","volume":"75","author":"Robertson","year":"1997","journal-title":"Bulletin of the World Health Organization"},{"key":"S0950268818000237_ref18","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/jit143"},{"key":"S0950268818000237_ref19","doi-asserted-by":"publisher","DOI":"10.7883\/yoken.JJID.2015.366"},{"key":"S0950268818000237_ref10","first-page":"319","article-title":"Rub\u00e9ola congenital \u2013 ainda entre n\u00f3s","volume":"8","author":"Saldanha","year":"1995","journal-title":"Acta Medica Portuguesa"}],"container-title":["Epidemiology and Infection"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S0950268818000237","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,1,30]],"date-time":"2020-01-30T04:44:12Z","timestamp":1580359452000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S0950268818000237\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,2,20]]},"references-count":22,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2018,4]]}},"alternative-id":["S0950268818000237"],"URL":"https:\/\/doi.org\/10.1017\/s0950268818000237","relation":{},"ISSN":["0950-2688","1469-4409"],"issn-type":[{"type":"print","value":"0950-2688"},{"type":"electronic","value":"1469-4409"}],"subject":[],"published":{"date-parts":[[2018,2,20]]},"assertion":[{"value":"Copyright \u00a9 Cambridge University Press 2018\u00a0","name":"license","label":"License","group":{"name":"copyright_and_licensing","label":"Copyright and Licensing"}}]}}