{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,2,15]],"date-time":"2023-02-15T05:30:42Z","timestamp":1676439042611},"reference-count":0,"publisher":"Oxford University Press (OUP)","issue":"S5","license":[{"start":{"date-parts":[[2012,9,28]],"date-time":"2012-09-28T00:00:00Z","timestamp":1348790400000},"content-version":"unspecified","delay-in-days":58,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Microsc Microanal"],"published-print":{"date-parts":[[2012,8]]},"abstract":"<jats:p>The use of transgenic plants for the large scale production of recombinant proteins with commercial and therapeutic value has emerged as an alternative to conventional platforms. Plant based systems, including whole plants and plant cell cultures offer many advantages particularly regarding safety and cost effectiveness. In our laboratory we have been using the model plant <jats:italic>Medicago truncatula<\/jats:italic> as a system to express recombinant proteins with a variety of applications.<\/jats:p>","DOI":"10.1017\/s1431927612012718","type":"journal-article","created":{"date-parts":[[2012,9,30]],"date-time":"2012-09-30T12:41:56Z","timestamp":1349008916000},"page":"11-12","source":"Crossref","is-referenced-by-count":1,"title":["Assessment of Medicago Based Systems for the Production of Human Proteins: Microscopy Analysis of the Subcellular Deposition Patterns of the Recombinant Product"],"prefix":"10.1093","volume":"18","author":[{"given":"R.B.","family":"Santos","sequence":"first","affiliation":[]},{"given":"A.S.","family":"Pires","sequence":"additional","affiliation":[]},{"given":"H.S.","family":"Silva","sequence":"additional","affiliation":[]},{"given":"and R.","family":"Abranches","sequence":"additional","affiliation":[]}],"member":"286","published-online":{"date-parts":[[2012,9,28]]},"container-title":["Microscopy and Microanalysis"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S1431927612012718","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,2,14]],"date-time":"2023-02-14T21:01:19Z","timestamp":1676408479000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/mam\/article\/18\/S5\/11\/6931928"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,8]]},"references-count":0,"journal-issue":{"issue":"S5","published-print":{"date-parts":[[2012,8]]}},"alternative-id":["S1431927612012718"],"URL":"https:\/\/doi.org\/10.1017\/s1431927612012718","relation":{},"ISSN":["1431-9276","1435-8115"],"issn-type":[{"value":"1431-9276","type":"print"},{"value":"1435-8115","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,8]]}}}