{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,13]],"date-time":"2025-05-13T22:01:13Z","timestamp":1747173673586,"version":"3.40.5"},"reference-count":22,"publisher":"Cambridge University Press (CUP)","issue":"4","license":[{"start":{"date-parts":[[2020,9,28]],"date-time":"2020-09-28T00:00:00Z","timestamp":1601251200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/www.cambridge.org\/core\/terms"}],"content-domain":{"domain":["cambridge.org"],"crossmark-restriction":true},"short-container-title":["Pall Supp Care"],"published-print":{"date-parts":[[2021,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec id=\"S1478951520000863_sec_a1\"><jats:title>Objective<\/jats:title><jats:p>Desire for death (DfD) is a complex and multifactorial dimension of end-of-life experience. We aimed to evaluate the prevalence of DfD and its associations, arising within the setting of a tertiary home-based palliative care (PC) unit.<\/jats:p><\/jats:sec><jats:sec id=\"S1478951520000863_sec_a2\" sec-type=\"methods\"><jats:title>Method<\/jats:title><jats:p>Retrospective analysis of all DfD entries registered in our anonymized database from October 2018 to April 2020.<\/jats:p><\/jats:sec><jats:sec id=\"S1478951520000863_sec_a3\" sec-type=\"results\"><jats:title>Results<\/jats:title><jats:p>Of the 163 patients anonymously registered in our database, 122 met entry criteria; 52% were male, the average age was 69 years old; 85% had malignancies, with a mean performance status (PPS) of 56%. The prevalence of DfD was 20%. No statistical differences were observed between patients with and without DfD regarding sex, age, marital status, religion, social support, prior PC or psychological follow-up, type of diagnosis, presence of advanced directives\/living will, time since diagnosis and PC team's follow-up time. Statistically significant associations were found between higher PPS scores and DfD (OR = 0.96; 95% confidence interval (CI) [0.93\u20130.99]); Edmonton Symptom Assessment Scale scores for drowsiness (OR = 4.05; 95% CI [1.42\u201311.57]), shortness of breath (OR = 3.35; 95% CI [1.09\u201310.31]), well-being (OR = 7.64; 95% CI [1.63\u201335.81]). DfD was associated with being depressed (OR = 19.24; 95% CI [3.09\u2013+inf]); feeling anxious (OR = 11.11; 95% CI [2.51\u201349.29]); HADS anxiety subscale \u226511 (OR = 25.0; 95% CI [2.10\u2013298.29]); will-to-live (OR = 39.53; 95% CI [4.85\u2013321.96]). Patients feeling a burden were more likely to desire death (OR = 14.67; 95% CI [1.85\u2013116.17]), as well as those who were not adapted to the disease (OR = 4.08; 95% CI [1.30\u201312.84]). In multivariate regression analyses predicting DfD, three independent factors emerged: higher PPS scores were associated with no DfD (aOR = 0.95; 95% CI [0.91\u20130.99]), while the sense of being a burden (aOR = 12.82; 95% CI [1.31\u2013125.16]) and worse well-being (aOR = 7.72; 95% CI [1.26\u201347.38]) predicted DfD.<\/jats:p><\/jats:sec><jats:sec id=\"S1478951520000863_sec_a4\"><jats:title>Significance of results<\/jats:title><jats:p>Prevalence of DfD was 20% and consistent with previous Portuguese evidence on DfD in PC inpatients. Both physical and psychosocial factors contribute to a stronger DfD.<\/jats:p><\/jats:sec>","DOI":"10.1017\/s1478951520000863","type":"journal-article","created":{"date-parts":[[2020,9,28]],"date-time":"2020-09-28T09:15:43Z","timestamp":1601284543000},"page":"457-463","update-policy":"https:\/\/doi.org\/10.1017\/policypage","source":"Crossref","is-referenced-by-count":5,"title":["The desire for death in Portuguese home-care palliative patients: Retrospective analysis of the prevalence and associated factors"],"prefix":"10.1017","volume":"19","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9283-5045","authenticated-orcid":false,"given":"Miguel","family":"Juli\u00e3o","sequence":"first","affiliation":[]},{"given":"Maria Ana","family":"Sobral","sequence":"additional","affiliation":[]},{"given":"Paula","family":"Cal\u00e7ada","sequence":"additional","affiliation":[]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1655-7391","authenticated-orcid":false,"given":"B\u00e1rbara","family":"Antunes","sequence":"additional","affiliation":[]},{"given":"Daniela","family":"Runa","sequence":"additional","affiliation":[]},{"given":"Catarina","family":"Samorinha","sequence":"additional","affiliation":[]},{"given":"Harvey Max","family":"Chochinov","sequence":"additional","affiliation":[]},{"given":"William","family":"Breitbart","sequence":"additional","affiliation":[]}],"member":"56","published-online":{"date-parts":[[2020,9,28]]},"reference":[{"key":"S1478951520000863_ref21","doi-asserted-by":"publisher","DOI":"10.17711\/SM.0185-3325.2019.014"},{"key":"S1478951520000863_ref9","doi-asserted-by":"publisher","DOI":"10.1017\/S1478951515000474"},{"key":"S1478951520000863_ref2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.284.22.2907"},{"key":"S1478951520000863_ref16","doi-asserted-by":"publisher","DOI":"10.1016\/j.genhosppsych.2005.02.004"},{"key":"S1478951520000863_ref13","doi-asserted-by":"publisher","DOI":"10.1017\/S1478951520000863"},{"key":"S1478951520000863_ref8","doi-asserted-by":"publisher","DOI":"10.1016\/j.psym.2013.01.006"},{"key":"S1478951520000863_ref19","doi-asserted-by":"publisher","DOI":"10.1136\/bmjspcare-2011-000011"},{"key":"S1478951520000863_ref3","doi-asserted-by":"crossref","first-page":"1185","DOI":"10.1176\/ajp.152.8.1185","article-title":"Desire for death in the terminally ill","volume":"152","author":"Chochinov","year":"1995","journal-title":"The American Journal of Psychiatry"},{"key":"S1478951520000863_ref22","doi-asserted-by":"publisher","DOI":"10.1136\/bmjspcare-2013-000604"},{"key":"S1478951520000863_ref11","doi-asserted-by":"publisher","DOI":"10.21037\/apm.2018.04.04"},{"key":"S1478951520000863_ref4","doi-asserted-by":"crossref","first-page":"674","DOI":"10.1176\/ajp.154.5.674","article-title":"\u201cAre you depressed?\u201d Screening for depression in the terminally ill","volume":"154","author":"Chochinov","year":"1997","journal-title":"The American Journal of Psychiatry"},{"key":"S1478951520000863_ref15","doi-asserted-by":"publisher","DOI":"10.1002\/pon.1839"},{"key":"S1478951520000863_ref12","doi-asserted-by":"publisher","DOI":"10.1089\/jpm.2019.0137"},{"key":"S1478951520000863_ref5","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpainsymman.2014.11.291"},{"key":"S1478951520000863_ref10","doi-asserted-by":"publisher","DOI":"10.1017\/S1478951516001140"},{"key":"S1478951520000863_ref7","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpainsymman.2016.10.370"},{"key":"S1478951520000863_ref6","doi-asserted-by":"publisher","DOI":"10.1177\/0269216306071799"},{"key":"#cr-split#-S1478951520000863_ref17.1","unstructured":"Palliative Care Needs Assessment Guidance [Internet] (2014). Place of publication: The National Clinical Programme for Palliative Care, HSE Clinical Strategy and Programmes Division [revised January 2016"},{"key":"#cr-split#-S1478951520000863_ref17.2","unstructured":"cited May 2020]. 13 pages. Available at: www.hse.ie\/palliativecareprogramme"},{"key":"S1478951520000863_ref1","unstructured":"Bernardo, A (2005) Avalia\u00e7\u00e3o de Sintomas em Cuidados Paliativos [MSc thesis]. Lisboa: Faculdadede Medicina da Universidade de Lisboa."},{"key":"S1478951520000863_ref14","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0037117"},{"key":"S1478951520000863_ref18","doi-asserted-by":"crossref","first-page":"711","DOI":"10.1177\/0269216315577748","article-title":"The desire to hasten death: Using Grounded Theory for a better understanding \u201cWhen perception of time tends to be a slippery slope\u201d","volume":"29","author":"Pestinger","year":"2015","journal-title":"Palliative Medicine"}],"container-title":["Palliative and Supportive Care"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cambridge.org\/core\/services\/aop-cambridge-core\/content\/view\/S1478951520000863","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,7,30]],"date-time":"2021-07-30T11:01:43Z","timestamp":1627642903000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cambridge.org\/core\/product\/identifier\/S1478951520000863\/type\/journal_article"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,9,28]]},"references-count":22,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2021,8]]}},"alternative-id":["S1478951520000863"],"URL":"https:\/\/doi.org\/10.1017\/s1478951520000863","relation":{},"ISSN":["1478-9515","1478-9523"],"issn-type":[{"type":"print","value":"1478-9515"},{"type":"electronic","value":"1478-9523"}],"subject":[],"published":{"date-parts":[[2020,9,28]]},"assertion":[{"value":"Copyright \u00a9 The Author(s), 2020. Published by Cambridge University Press","name":"copyright","label":"Copyright","group":{"name":"copyright_and_licensing","label":"Copyright and Licensing"}}]}}