{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T14:05:38Z","timestamp":1792677938271,"version":"4.5.0"},"reference-count":40,"publisher":"American Chemical Society (ACS)","issue":"7","license":[{"start":{"date-parts":[[2023,3,30]],"date-time":"2023-03-30T00:00:00Z","timestamp":1680134400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2023,3,30]],"date-time":"2023-03-30T00:00:00Z","timestamp":1680134400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2023,3,30]],"date-time":"2023-03-30T00:00:00Z","timestamp":1680134400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-045"}],"funder":[{"DOI":"10.13039\/100012555","name":"Russian Foundation for Fundamental Investigations","doi-asserted-by":"publisher","award":["122030100170-5"],"award-info":[{"award-number":["122030100170-5"]}],"id":[{"id":"10.13039\/100012555","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002261","name":"RFBR","doi-asserted-by":"crossref","award":["17-54-30015-NIH_a"],"award-info":[{"award-number":["17-54-30015-NIH_a"]}],"id":[{"id":"10.13039\/501100002261","id-type":"DOI","asserted-by":"crossref"}]},{"name":"RFBR\/DST","award":["11-04-92713-IND_a\/RUSP-1176"],"award-info":[{"award-number":["11-04-92713-IND_a\/RUSP-1176"]}]},{"name":"RSF\/DST","award":["INT\/RUS\/RSF\/12-16-45-02012"],"award-info":[{"award-number":["INT\/RUS\/RSF\/12-16-45-02012"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2023,4,10]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Medicinal plants growing in Russia are a rich source of biologically active compounds. However, the evaluation of the hidden pharmacological potential of these compounds by in silico methods is complicated by the lack of specialized databases. We have created a database of 3128 phytocomponents from 268 medical plants included in the Russian Pharmacopoeia. The information about the compounds was supplemented with their physical-chemical characteristics and biological activity profiles estimated using the PASS software. Comparison with phytocomponents of medicinal plants from five other countries showed that the similarity of phytocomponents in our database is rather small. The uniqueness of the contents significantly enriches and provides easy access to the necessary information. The Phyto4Health data are freely available at http:\/\/www.way2drug.com\/p4h\/.<\/jats:p>","DOI":"10.1021\/acs.jcim.2c01567","type":"journal-article","created":{"date-parts":[[2023,3,30]],"date-time":"2023-03-30T12:57:26Z","timestamp":1680181046000},"page":"1847-1851","source":"Crossref","is-referenced-by-count":15,"title":["Phyto4Health: Database\nof Phytocomponents from Russian\nPharmacopoeia Plants"],"prefix":"10.1021","volume":"63","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5396-2789","authenticated-orcid":true,"given":"Nikita","family":"Ionov","sequence":"first","affiliation":[{"name":"Institute of Biomedical Chemistry (IBMC) , 10 Bldg. 8, Pogodinskaya Str. , ,","place":["Moscow, Russia, 119121"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dmitry","family":"Druzhilovskiy","sequence":"additional","affiliation":[{"name":"Institute of Biomedical Chemistry (IBMC) , 10 Bldg. 8, Pogodinskaya Str. , ,","place":["Moscow, Russia, 119121"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0339-8478","authenticated-orcid":true,"given":"Dmitry","family":"Filimonov","sequence":"additional","affiliation":[{"name":"Institute of Biomedical Chemistry (IBMC) , 10 Bldg. 8, Pogodinskaya Str. , ,","place":["Moscow, Russia, 119121"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7937-2621","authenticated-orcid":true,"given":"Vladimir","family":"Poroikov","sequence":"additional","affiliation":[{"name":"Institute of Biomedical Chemistry (IBMC) , 10 Bldg. 8, Pogodinskaya Str. , ,","place":["Moscow, Russia, 119121"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2023,3,30]]},"reference":[{"issue":"3","key":"2026081804440131200_cit1","doi-asserted-by":"publisher","first-page":"770","DOI":"10.1021\/acs.jnatprod.9b01285","article-title":"Natural Products as Sources of New Drugs over the Nearly\nFour Decades from 01\/1981 to 09\/2019","volume":"83","author":"Newman","year":"2020","journal-title":"J. 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Drug Discovery"},{"issue":"10","key":"2026081804440131200_cit5","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0078085","article-title":"AfroDb: A Select Highly\nPotent and Diverse Natural\nProduct Library from African Medicinal Plants","volume":"8","author":"Ntie-Kang","year":"2013","journal-title":"PLoS One"},{"issue":"2","key":"2026081804440131200_cit6","doi-asserted-by":"publisher","first-page":"286","DOI":"10.18097\/PBMC20156102286","volume":"61","author":"Lagunin","year":"2015","journal-title":"Biomed. Khim."},{"key":"2026081804440131200_cit7","doi-asserted-by":"publisher","first-page":"218","DOI":"10.1186\/s12906-015-0758-5","article-title":"TM-MC: a database\nof medicinal materials and chemical compounds in Northeast Asian traditional\nmedicine","volume":"15","author":"Kim","year":"2015","journal-title":"BMC Complementary Altern. Med."},{"key":"2026081804440131200_cit8","doi-asserted-by":"publisher","first-page":"113685","DOI":"10.1016\/j.jep.2020.113685","article-title":"Medicinal\nplants from the 14th edition of the Russian Pharmacopoeia, recent\nupdates","volume":"268","author":"Shikov","year":"2021","journal-title":"J. Ethnopharmacol."},{"issue":"3","key":"2026081804440131200_cit9","doi-asserted-by":"publisher","first-page":"278","DOI":"10.18097\/pbmc20216703278","article-title":"Possibilities of in Silico Estimations for the Development\nof the Pharmaceutical Composition Phytoladaptogene Cytotoxic for Bladder\nCancer Cells","volume":"67","author":"Ionov","year":"2021","journal-title":"Biomed. 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Kunth","volume":"59","author":"Al-Madhagi","year":"2019","journal-title":"J.\nChem. Inf. Model."},{"issue":"1","key":"2026081804440131200_cit13","doi-asserted-by":"publisher","first-page":"20","DOI":"10.1186\/s13321-020-00424-9","article-title":"Review on\nNatural Products Databases: Where to Find\nData in 2020","volume":"12","author":"Sorokina","year":"2020","journal-title":"J. Cheminf."},{"issue":"2022","key":"2026081804440131200_cit14","doi-asserted-by":"publisher","first-page":"baac002","DOI":"10.1093\/database\/baac002","article-title":"phytochemdb: a platform\nfor virtual screening and computer-aided\ndrug designing","volume":"2022","author":"Mahmud","year":"2022","journal-title":"Database"},{"issue":"6","key":"2026081804440131200_cit15","doi-asserted-by":"publisher","first-page":"2516","DOI":"10.1021\/acs.jcim.1c00083","article-title":"SistematX:\nWeb portal of natural\nproducts","volume":"61","author":"Costa","year":"2021","journal-title":"J. Chem. Inf. 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Food Chem."},{"issue":"1","key":"2026081804440131200_cit40","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1186\/s13321-016-0159-x","article-title":"Mixtures, metabolites,\nionic liquids: a new measure to evaluate similarity between complex\nchemical systems","volume":"8","author":"Mauri","year":"2016","journal-title":"J. Cheminf."}],"container-title":["Journal of Chemical Information\nand Modeling"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acs.jcim.2c01567","content-type":"application\/pdf","content-version":"vor","intended-application":"unspecified"},{"URL":"https:\/\/pubs.acs.org\/jcisd8\/article-pdf\/63\/7\/1847\/8908818\/ci2c01567.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/pubs.acs.org\/jcisd8\/article-pdf\/63\/7\/1847\/8908818\/ci2c01567.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T09:01:20Z","timestamp":1787043680000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/jcisd8\/article\/63\/7\/1847\/850302\/Phyto4Health-Database-of-Phytocomponents-from"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,3,30]]},"references-count":40,"journal-issue":{"issue":"7","published-online":{"date-parts":[[2023,3,30]]},"published-print":{"date-parts":[[2023,4,10]]}},"URL":"https:\/\/doi.org\/10.1021\/acs.jcim.2c01567","relation":{},"ISSN":["1549-9596","1549-960X"],"issn-type":[{"value":"1549-9596","type":"print"},{"value":"1549-960X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,3,30]]}}}