{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,9]],"date-time":"2026-07-09T23:56:31Z","timestamp":1783641391700,"version":"3.55.0"},"reference-count":43,"publisher":"American Chemical Society (ACS)","issue":"22","license":[{"start":{"date-parts":[[2025,11,11]],"date-time":"2025-11-11T00:00:00Z","timestamp":1762819200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2025,11,11]],"date-time":"2025-11-11T00:00:00Z","timestamp":1762819200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2025,11,11]],"date-time":"2025-11-11T00:00:00Z","timestamp":1762819200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-045"}],"funder":[{"DOI":"10.13039\/501100002855","name":"Ministry of Science and Technology of the People's Republic of China","doi-asserted-by":"publisher","award":["2021ZD0203000(2021ZD0203003"],"award-info":[{"award-number":["2021ZD0203000(2021ZD0203003"]}],"id":[{"id":"10.13039\/501100002855","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["T2350008"],"award-info":[{"award-number":["T2350008"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002367","name":"Chinese Academy of Sciences","doi-asserted-by":"publisher","award":["029GJHZ2024057GC"],"award-info":[{"award-number":["029GJHZ2024057GC"]}],"id":[{"id":"10.13039\/501100002367","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Chem. Inf. Model."],"published-print":{"date-parts":[[2025,11,24]]},"DOI":"10.1021\/acs.jcim.5c02156","type":"journal-article","created":{"date-parts":[[2025,11,11]],"date-time":"2025-11-11T19:10:17Z","timestamp":1762888217000},"page":"12524-12535","source":"Crossref","is-referenced-by-count":2,"title":["Cooperative Ionic Coordination Governs Dopamine Transporter Dynamics and Substrate Translocation: Mechanistic Insights from Molecular Simulations"],"prefix":"10.1021","volume":"65","author":[{"given":"Cong","family":"Zhang","sequence":"first","affiliation":[{"name":"Interdisciplinary Laboratory for Frontier Chemistry","place":["Changchun, China"]},{"name":"Changchun Institute of Applied Chemistry, Chinese Academy of Sciences","place":["Changchun, China"]},{"name":"School of Applied Chemistry and Engineering","place":["Hefei, China"]},{"name":"University of Science and Technology of China","place":["Hefei, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pu","family":"Jiang","sequence":"additional","affiliation":[{"name":"Interdisciplinary Laboratory for Frontier Chemistry","place":["Changchun, China"]},{"name":"Changchun Institute of Applied Chemistry, Chinese Academy of Sciences","place":["Changchun, China"]},{"name":"School of Applied Chemistry and Engineering","place":["Hefei, China"]},{"name":"University of Science and Technology of China","place":["Hefei, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Penghui","family":"Li","sequence":"additional","affiliation":[{"name":"Interdisciplinary Laboratory for Frontier Chemistry","place":["Changchun, China"]},{"name":"Changchun Institute of Applied Chemistry, Chinese Academy of Sciences","place":["Changchun, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yibo","family":"Wang","sequence":"additional","affiliation":[{"name":"Interdisciplinary Laboratory for Frontier Chemistry","place":["Changchun, China"]},{"name":"Changchun Institute of Applied Chemistry, Chinese Academy of Sciences","place":["Changchun, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3415-5612","authenticated-orcid":true,"given":"Xiaohui","family":"Wang","sequence":"additional","affiliation":[{"name":"Interdisciplinary Laboratory for Frontier Chemistry","place":["Changchun, China"]},{"name":"Changchun Institute of Applied Chemistry, Chinese Academy of Sciences","place":["Changchun, China"]},{"name":"School of Applied Chemistry and Engineering","place":["Hefei, China"]},{"name":"University of Science and Technology of China","place":["Hefei, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2025,11,11]]},"reference":[{"key":"ref1\/cit1","doi-asserted-by":"publisher","DOI":"10.1038\/nrn1008"},{"key":"ref2\/cit2","doi-asserted-by":"publisher","DOI":"10.1038\/s41586-024-07796-0"},{"key":"ref3\/cit3","doi-asserted-by":"publisher","DOI":"10.1016\/j.tips.2013.07.005"},{"key":"ref4\/cit4","doi-asserted-by":"publisher","DOI":"10.1038\/mp.2016.74"},{"key":"ref5\/cit5","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp-2017-315985"},{"key":"ref6\/cit6","doi-asserted-by":"publisher","DOI":"10.1038\/d41586-024-02435-0"},{"key":"ref7\/cit7","doi-asserted-by":"publisher","DOI":"10.1038\/s41586-024-07804-3"},{"key":"ref8\/cit8","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.17-03-00960.1997"},{"key":"ref9\/cit9","doi-asserted-by":"publisher","DOI":"10.1016\/j.str.2015.09.001"},{"key":"ref10\/cit10","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0016350"},{"key":"ref11\/cit11","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pcbi.1003296"},{"key":"ref12\/cit12","doi-asserted-by":"publisher","DOI":"10.1038\/srep40076"},{"key":"ref13\/cit13","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M114.574269"},{"key":"ref14\/cit14","doi-asserted-by":"publisher","DOI":"10.3389\/fchem.2021.753990"},{"key":"ref15\/cit15","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3565(25)23750-8"},{"key":"ref16\/cit16","doi-asserted-by":"publisher","DOI":"10.1002\/jcc.20945"},{"key":"ref17\/cit17","doi-asserted-by":"publisher","DOI":"10.1016\/j.bpj.2017.10.017"},{"key":"ref18\/cit18","doi-asserted-by":"publisher","DOI":"10.1002\/jcc.20291"},{"key":"ref19\/cit19","doi-asserted-by":"publisher","DOI":"10.1038\/nmeth.4067"},{"key":"ref20\/cit20","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jcim.3c01153"},{"key":"ref21\/cit21","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1096-987X(199709)18:12<1463::AID-JCC4>3.0.CO;2-H"},{"key":"ref22\/cit22","doi-asserted-by":"publisher","DOI":"10.1063\/1.464397"},{"key":"ref23\/cit23","doi-asserted-by":"publisher","DOI":"10.1063\/1.470117"},{"key":"ref24\/cit24","doi-asserted-by":"publisher","DOI":"10.1080\/00268978300102851"},{"key":"ref25\/cit25","doi-asserted-by":"publisher","DOI":"10.1063\/1.328693"},{"key":"ref26\/cit26","doi-asserted-by":"publisher","DOI":"10.1103\/PhysRevA.31.1695"},{"key":"ref27\/cit27","doi-asserted-by":"publisher","DOI":"10.1080\/00268978400101201"},{"key":"ref28\/cit28","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jctc.5b01202"},{"key":"ref29\/cit29","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuron.2018.02.016"},{"key":"ref30\/cit30","doi-asserted-by":"publisher","DOI":"10.1002\/jcc.21787"},{"key":"ref31\/cit31","doi-asserted-by":"publisher","DOI":"10.1186\/s13321-021-00548-6"},{"key":"ref32\/cit32","doi-asserted-by":"publisher","DOI":"10.1016\/0263-7855(96)00018-5"},{"key":"ref33\/cit33","unstructured":"PyMOL, The PyMol molecular graphics system. Version 2.6.0; Schr\u00f6dinger, LLC."},{"key":"ref34\/cit34","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.202427399"},{"key":"ref35\/cit35","doi-asserted-by":"publisher","DOI":"10.1103\/PhysRevLett.100.020603"},{"key":"ref36\/cit36","doi-asserted-by":"publisher","DOI":"10.1002\/jcc.540130812"},{"key":"ref37\/cit37","doi-asserted-by":"publisher","DOI":"10.1021\/ct100494z"},{"key":"ref38\/cit38","doi-asserted-by":"publisher","DOI":"10.1063\/1.2976440"},{"key":"ref39\/cit39","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.RA118.001753"},{"key":"ref40\/cit40","doi-asserted-by":"publisher","DOI":"10.1172\/JCI73778"},{"key":"ref41\/cit41","doi-asserted-by":"publisher","DOI":"10.1038\/s41586-024-07719-z"},{"key":"ref42\/cit42","doi-asserted-by":"publisher","DOI":"10.1038\/s41580-022-00524-4"},{"key":"ref43\/cit43","doi-asserted-by":"publisher","DOI":"10.1021\/acs.chemrev.8b00608"}],"container-title":["Journal of Chemical Information and Modeling"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acs.jcim.5c02156","content-type":"application\/pdf","content-version":"vor","intended-application":"unspecified"},{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acs.jcim.5c02156","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,11,24]],"date-time":"2025-11-24T09:11:18Z","timestamp":1763975478000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/acs.jcim.5c02156"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,11,11]]},"references-count":43,"journal-issue":{"issue":"22","published-print":{"date-parts":[[2025,11,24]]}},"alternative-id":["10.1021\/acs.jcim.5c02156"],"URL":"https:\/\/doi.org\/10.1021\/acs.jcim.5c02156","relation":{},"ISSN":["1549-9596","1549-960X"],"issn-type":[{"value":"1549-9596","type":"print"},{"value":"1549-960X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,11,11]]}}}