{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,14]],"date-time":"2026-05-14T20:18:11Z","timestamp":1778789891761,"version":"3.51.4"},"reference-count":34,"publisher":"American Chemical Society (ACS)","issue":"5","license":[{"start":{"date-parts":[[2026,2,26]],"date-time":"2026-02-26T00:00:00Z","timestamp":1772064000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,2,26]],"date-time":"2026-02-26T00:00:00Z","timestamp":1772064000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,2,26]],"date-time":"2026-02-26T00:00:00Z","timestamp":1772064000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-045"}],"funder":[{"DOI":"10.13039\/501100004735","name":"Natural Science Foundation of Hunan Province","doi-asserted-by":"publisher","award":["2025JJ20062"],"award-info":[{"award-number":["2025JJ20062"]}],"id":[{"id":"10.13039\/501100004735","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["62272490"],"award-info":[{"award-number":["62272490"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["U23A20321"],"award-info":[{"award-number":["U23A20321"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Chem. Inf. Model."],"published-print":{"date-parts":[[2026,3,9]]},"DOI":"10.1021\/acs.jcim.5c02935","type":"journal-article","created":{"date-parts":[[2026,2,26]],"date-time":"2026-02-26T09:51:00Z","timestamp":1772099460000},"page":"2791-2806","source":"Crossref","is-referenced-by-count":1,"title":["TwistDAN: Twisted Domain Adversarial Network for Synthetic Accessibility Assessment"],"prefix":"10.1021","volume":"66","author":[{"ORCID":"https:\/\/orcid.org\/0009-0005-7749-1930","authenticated-orcid":true,"given":"Qahtan Adnan","family":"Aljanabi","sequence":"first","affiliation":[{"name":"School of Computer Science and Engineering","place":["Changsha, China"]},{"name":"Central South University","place":["Changsha, China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0000-1949-167X","authenticated-orcid":true,"given":"Zhijian","family":"Huang","sequence":"additional","affiliation":[{"name":"School of Computer Science and Engineering","place":["Changsha, China"]},{"name":"Central South University","place":["Changsha, China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ziyu","family":"Fan","sequence":"additional","affiliation":[{"name":"School of Computer Science and Engineering","place":["Changsha, China"]},{"name":"Central South University","place":["Changsha, China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shangqian","family":"Wu","sequence":"additional","affiliation":[{"name":"School of Computer Science and Engineering","place":["Changsha, China"]},{"name":"Central South University","place":["Changsha, China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shuhong","family":"Liu","sequence":"additional","affiliation":[{"name":"School of Computer Science and Engineering","place":["Changsha, China"]},{"name":"Central South University","place":["Changsha, China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Meng","family":"Chen","sequence":"additional","affiliation":[{"name":"School of Software","place":["Urumqi, China"]},{"name":"Xinjiang University","place":["Urumqi, China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hang","family":"Chen","sequence":"additional","affiliation":[{"name":"School of Computer Science and Engineering","place":["Changsha, China"]},{"name":"Central South University","place":["Changsha, China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuanpeng","family":"Zhang","sequence":"additional","affiliation":[{"name":"School of Computer Science and Engineering","place":["Changsha, China"]},{"name":"Central South University","place":["Changsha, China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jiangtao","family":"Xu","sequence":"additional","affiliation":[{"name":"School of Software","place":["Urumqi, China"]},{"name":"Xinjiang University","place":["Urumqi, China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lei","family":"Deng","sequence":"additional","affiliation":[{"name":"School of Computer Science and Engineering","place":["Changsha, China"]},{"name":"Central South University","place":["Changsha, China"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"316","published-online":{"date-parts":[[2026,2,26]]},"reference":[{"key":"ref1\/cit1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jcim.0c00174"},{"key":"ref2\/cit2","doi-asserted-by":"publisher","DOI":"10.1186\/1758-2946-1-8"},{"key":"ref3\/cit3","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhealeco.2016.01.012"},{"key":"ref4\/cit4","doi-asserted-by":"publisher","DOI":"10.21203\/rs.2.22597\/v1"},{"key":"ref5\/cit5","doi-asserted-by":"publisher","DOI":"10.1186\/s13321-024-00879-0"},{"key":"ref6\/cit6","doi-asserted-by":"publisher","DOI":"10.1186\/s13321-020-00472-1"},{"key":"ref7\/cit7","doi-asserted-by":"publisher","DOI":"10.1021\/acs.accounts.5c00155"},{"key":"ref8\/cit8","doi-asserted-by":"publisher","DOI":"10.1039\/D0SC05401A"},{"key":"ref9\/cit9","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jcim.7b00622"},{"key":"ref10\/cit10","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1186\/s13321-023-00678-z","volume":"15","author":"Skoraczy\u0144ski G.","year":"2023","journal-title":"J. Cheminf."},{"key":"ref11\/cit11","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jcim.2c00038"},{"key":"ref12\/cit12","doi-asserted-by":"publisher","DOI":"10.1186\/s13321-023-00771-3"},{"key":"ref13\/cit13","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jcim.3c01134"},{"key":"ref14\/cit14","doi-asserted-by":"publisher","DOI":"10.48550\/arXiv.2403.13005"},{"key":"ref15\/cit15","doi-asserted-by":"publisher","DOI":"10.1021\/ci034043l"},{"key":"ref16\/cit16","doi-asserted-by":"publisher","DOI":"10.1002\/cmtd.202400024"},{"key":"ref17\/cit17","first-page":"1180","author":"Ganin Y.","year":"2015","journal-title":"Proc. 32nd Int. Conf. Mach. Learn."},{"key":"ref18\/cit18","doi-asserted-by":"publisher","DOI":"10.48550\/arXiv.2006.15820"},{"key":"ref19\/cit19","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkw1074"},{"key":"ref20\/cit20","doi-asserted-by":"publisher","DOI":"10.3389\/fchem.2020.00046"},{"key":"ref21\/cit21","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jcim.5b00559"},{"key":"ref22\/cit22","doi-asserted-by":"publisher","DOI":"10.1186\/s13321-017-0206-2"},{"key":"ref23\/cit23","doi-asserted-by":"publisher","DOI":"10.1021\/jm9602928"},{"key":"ref24\/cit24","doi-asserted-by":"publisher","DOI":"10.1021\/ci300415d"},{"key":"ref25\/cit25","doi-asserted-by":"publisher","DOI":"10.1021\/ci100216g"},{"key":"ref26\/cit26","doi-asserted-by":"publisher","DOI":"10.1007\/s10822-006-9099-2"},{"key":"ref27\/cit27","doi-asserted-by":"publisher","DOI":"10.1021\/ci500568d"},{"key":"ref28\/cit28","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkv951"},{"key":"ref29\/cit29","doi-asserted-by":"publisher","DOI":"10.1021\/ci5001778"},{"key":"ref30\/cit30","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jcim.4c01663"},{"key":"ref31\/cit31","first-page":"1205","volume":"25","author":"Gretton A.","year":"2012","journal-title":"Adv. Neural Inf. Process. Syst."},{"key":"ref32\/cit32","doi-asserted-by":"publisher","DOI":"10.48550\/arXiv.1812.11806"},{"key":"ref33\/cit33","doi-asserted-by":"publisher","DOI":"10.3389\/fphar.2020.565644"},{"key":"ref34\/cit34","doi-asserted-by":"publisher","DOI":"10.1186\/s13321-020-00478-9"}],"container-title":["Journal of Chemical Information and Modeling"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acs.jcim.5c02935","content-type":"application\/pdf","content-version":"vor","intended-application":"unspecified"},{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acs.jcim.5c02935","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,3,10]],"date-time":"2026-03-10T07:39:32Z","timestamp":1773128372000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/acs.jcim.5c02935"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,2,26]]},"references-count":34,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2026,3,9]]}},"alternative-id":["10.1021\/acs.jcim.5c02935"],"URL":"https:\/\/doi.org\/10.1021\/acs.jcim.5c02935","relation":{},"ISSN":["1549-9596","1549-960X"],"issn-type":[{"value":"1549-9596","type":"print"},{"value":"1549-960X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,2,26]]}}}