{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,11]],"date-time":"2026-03-11T05:33:04Z","timestamp":1773207184106,"version":"3.50.1"},"reference-count":45,"publisher":"American Chemical Society (ACS)","issue":"5","license":[{"start":{"date-parts":[[2026,2,19]],"date-time":"2026-02-19T00:00:00Z","timestamp":1771459200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,2,19]],"date-time":"2026-02-19T00:00:00Z","timestamp":1771459200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,2,19]],"date-time":"2026-02-19T00:00:00Z","timestamp":1771459200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-045"}],"funder":[{"name":"National Foreign Expert Human Project (Class H)","award":["H20240929"],"award-info":[{"award-number":["H20240929"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Chem. Inf. Model."],"published-print":{"date-parts":[[2026,3,9]]},"DOI":"10.1021\/acs.jcim.5c02963","type":"journal-article","created":{"date-parts":[[2026,2,20]],"date-time":"2026-02-20T04:53:57Z","timestamp":1771563237000},"page":"2929-2940","source":"Crossref","is-referenced-by-count":0,"title":["RCLG-PPIS: Structure-Aware Protein\u2013Protein Interaction Site Prediction with Cascaded Local and Global Information"],"prefix":"10.1021","volume":"66","author":[{"given":"Jing","family":"Chen","sequence":"first","affiliation":[{"name":"School of Artificial Intelligence and Computer Science","place":["Wuxi, China"]},{"name":"Jiangnan University","place":["Wuxi, China"]},{"name":"Jiangsu Provincial Engineering Laboratory of Pattern Recognition and Computing Intelligence","place":["Wuxi, China"]},{"name":"Jiangnan University","place":["Wuxi, China"]}]},{"ORCID":"https:\/\/orcid.org\/0009-0007-9649-0233","authenticated-orcid":true,"given":"Xiaobo","family":"Ge","sequence":"additional","affiliation":[{"name":"School of Artificial Intelligence and Computer Science","place":["Wuxi, China"]},{"name":"Jiangnan University","place":["Wuxi, China"]}]},{"given":"Qiuyao","family":"Qi","sequence":"additional","affiliation":[{"name":"School of Artificial Intelligence and Computer Science","place":["Wuxi, China"]},{"name":"Jiangnan University","place":["Wuxi, China"]}]},{"given":"Hengrui","family":"Zhang","sequence":"additional","affiliation":[{"name":"School of Artificial Intelligence and Computer Science","place":["Wuxi, China"]},{"name":"Jiangnan University","place":["Wuxi, China"]}]},{"given":"Tingbin","family":"Luo","sequence":"additional","affiliation":[{"name":"School of Artificial Intelligence and Computer Science","place":["Wuxi, China"]},{"name":"Jiangnan University","place":["Wuxi, China"]}]}],"member":"316","published-online":{"date-parts":[[2026,2,19]]},"reference":[{"key":"ref1\/cit1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.chemrev.3c00377"},{"key":"ref2\/cit2","doi-asserted-by":"publisher","DOI":"10.2174\/221279680901151109161126"},{"key":"ref3\/cit3","doi-asserted-by":"publisher","DOI":"10.1016\/j.jmb.2004.02.040"},{"key":"ref4\/cit4","doi-asserted-by":"publisher","DOI":"10.1021\/ja053565+"},{"key":"ref5\/cit5","doi-asserted-by":"publisher","DOI":"10.1155\/2010\/924529"},{"key":"ref6\/cit6","doi-asserted-by":"publisher","DOI":"10.1093\/bioinformatics\/btq302"},{"key":"ref7\/cit7","doi-asserted-by":"publisher","DOI":"10.1093\/bioinformatics\/btx585"},{"key":"ref8\/cit8","doi-asserted-by":"publisher","DOI":"10.3390\/ijms21072274"},{"key":"ref9\/cit9","doi-asserted-by":"publisher","DOI":"10.1109\/tcbb.2019.2953908"},{"key":"ref10\/cit10","doi-asserted-by":"publisher","DOI":"10.1093\/bioinformatics\/btaa750"},{"key":"ref11\/cit11","doi-asserted-by":"publisher","DOI":"10.1093\/bioinformatics\/btz699"},{"key":"ref12\/cit12","doi-asserted-by":"publisher","DOI":"10.1016\/j.neucom.2019.05.013"},{"key":"ref13\/cit13","doi-asserted-by":"publisher","DOI":"10.1093\/bioinformatics\/btab643"},{"key":"ref14\/cit14","doi-asserted-by":"publisher","DOI":"10.1093\/bib\/bbad122"},{"key":"ref15\/cit15","doi-asserted-by":"publisher","DOI":"10.1093\/bib\/bbad345"},{"key":"ref16\/cit16","doi-asserted-by":"publisher","DOI":"10.1016\/j.compbiomed.2023.107683"},{"key":"ref17\/cit17","doi-asserted-by":"publisher","DOI":"10.1093\/bib\/bbaf079"},{"key":"ref18\/cit18","doi-asserted-by":"publisher","DOI":"10.1016\/j.knosys.2024.112209"},{"key":"ref19\/cit19","doi-asserted-by":"crossref","unstructured":"Dai, H.; Song, H.; Han, T.; Yang, Q.; Meng, X.; Wang, X. AEG-PPIS: A Dual-Branch Protein-protein Interaction Site Predictor Based on Augmented Graph Attention Network and Equivariant Graph Neural Network. In\n                      IEEE International Conference on Bioinformatics and Biomedicine (BIBM)\n                      , 2024, pp 417\u2013422.","DOI":"10.1109\/BIBM62325.2024.10822268"},{"key":"ref20\/cit20","unstructured":"Satorras, V. G.; Hoogeboom, E.; Welling, M. E(n) equivariant graph neural networks. In\n                      International conference on machine learning\n                      , 2021, pp 9323\u20139332."},{"key":"ref21\/cit21","doi-asserted-by":"publisher","DOI":"10.48550\/arXiv.2202.07230"},{"key":"ref22\/cit22","doi-asserted-by":"publisher","DOI":"10.1093\/bib\/bbab502"},{"key":"ref23\/cit23","doi-asserted-by":"publisher","DOI":"10.1093\/bioinformatics\/btad340"},{"key":"ref24\/cit24","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijbiomac.2024.137272"},{"key":"ref25\/cit25","doi-asserted-by":"publisher","DOI":"10.1002\/prot.26763"},{"key":"ref26\/cit26","doi-asserted-by":"publisher","DOI":"10.1093\/bib\/bbaf290"},{"key":"ref27\/cit27","doi-asserted-by":"publisher","DOI":"10.1016\/j.jtbi.2014.01.028"},{"key":"ref28\/cit28","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-2836(05)80360-2"},{"key":"ref29\/cit29","doi-asserted-by":"publisher","DOI":"10.1002\/pro.3295"},{"key":"ref30\/cit30","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/25.17.3389"},{"key":"ref31\/cit31","doi-asserted-by":"publisher","DOI":"10.1038\/nmeth.1818"},{"key":"ref32\/cit32","doi-asserted-by":"publisher","DOI":"10.1002\/bip.360221211"},{"key":"ref33\/cit33","doi-asserted-by":"crossref","unstructured":"Liu, M.; Gao, H.; Ji, S. Towards deeper graph neural networks. In\n                      Proceedings of the 26th ACM SIGKDD international conference on knowledge discovery & data mining\n                      , 2020, pp 338\u2013348.","DOI":"10.1145\/3394486.3403076"},{"key":"ref34\/cit34","doi-asserted-by":"crossref","unstructured":"Ramp\u00e1\u0161ek, L.; Galkin, M.; Dwivedi, V. P.; Luu, A. T.; Wolf, G.; Beaini, D. Recipe for a general, powerful, scalable graph transformer. In\n                      Proceedings of the 36th International Conference on Neural Information Processing Systems\n                      , 2022, pp 14501\u201314515.","DOI":"10.52202\/068431-1054"},{"key":"ref35\/cit35","doi-asserted-by":"crossref","unstructured":"Dwivedi, V. P.; Ramp\u00e1\u0161ek, L.; Galkin, M.; Parviz, A.; Wolf, G.; Luu, A. T.; Beaini, D. Long range graph benchmark. In\n                      Proceedings of the 36th International Conference on Neural Information Processing Systems\n                      , 2022, pp 22326\u201322340.","DOI":"10.52202\/068431-1622"},{"key":"ref36\/cit36","doi-asserted-by":"publisher","DOI":"10.48550\/arXiv.2410.09737"},{"key":"ref37\/cit37","unstructured":"Rustamov, R. M. others Laplace-Beltrami eigenfunctions for deformation invariant shape representation. In\n                      Proceedings of the Fifth Eurographics Symposium on Geometry Processing\n                      , 2007, pp 225\u2013233."},{"key":"ref38\/cit38","doi-asserted-by":"publisher","DOI":"10.1002\/cem.1122"},{"key":"ref39\/cit39","doi-asserted-by":"publisher","DOI":"10.5555\/3648699.3648742"},{"key":"ref40\/cit40","doi-asserted-by":"publisher","DOI":"10.48550\/arXiv.2012.09699"},{"key":"ref41\/cit41","doi-asserted-by":"publisher","DOI":"10.48550\/arXiv.1609.02907"},{"key":"ref42\/cit42","doi-asserted-by":"publisher","DOI":"10.1016\/j.jmb.2020.02.026"},{"key":"ref43\/cit43","doi-asserted-by":"publisher","DOI":"10.1093\/bioinformatics\/btad718"},{"key":"ref44\/cit44","doi-asserted-by":"publisher","DOI":"10.1109\/TPAMI.2021.3095381"},{"key":"ref45\/cit45","doi-asserted-by":"publisher","DOI":"10.1126\/science.ade2574"}],"container-title":["Journal of Chemical Information and Modeling"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acs.jcim.5c02963","content-type":"application\/pdf","content-version":"vor","intended-application":"unspecified"},{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acs.jcim.5c02963","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,3,10]],"date-time":"2026-03-10T07:41:34Z","timestamp":1773128494000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/acs.jcim.5c02963"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,2,19]]},"references-count":45,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2026,3,9]]}},"alternative-id":["10.1021\/acs.jcim.5c02963"],"URL":"https:\/\/doi.org\/10.1021\/acs.jcim.5c02963","relation":{},"ISSN":["1549-9596","1549-960X"],"issn-type":[{"value":"1549-9596","type":"print"},{"value":"1549-960X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,2,19]]}}}