{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,14]],"date-time":"2026-02-14T03:51:21Z","timestamp":1771041081528,"version":"3.50.1"},"reference-count":77,"publisher":"American Chemical Society (ACS)","issue":"6","funder":[{"DOI":"10.13039\/100000051","name":"National Human Genome Research Institute","doi-asserted-by":"publisher","award":["U41HG006941"],"award-info":[{"award-number":["U41HG006941"]}],"id":[{"id":"10.13039\/100000051","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004410","name":"T?rkiye Bilimsel ve Teknolojik Arastirma Kurumu","doi-asserted-by":"publisher","award":["110T624"],"award-info":[{"award-number":["110T624"]}],"id":[{"id":"10.13039\/501100004410","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001321","name":"National Research Foundation","doi-asserted-by":"publisher","award":["93690"],"award-info":[{"award-number":["93690"]}],"id":[{"id":"10.13039\/501100001321","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Chem. Inf. Model."],"published-print":{"date-parts":[[2017,6,26]]},"DOI":"10.1021\/acs.jcim.6b00775","type":"journal-article","created":{"date-parts":[[2017,5,15]],"date-time":"2017-05-15T22:13:56Z","timestamp":1494886436000},"page":"1359-1374","source":"Crossref","is-referenced-by-count":71,"title":["Perturbation\u2013Response Scanning Reveals Key Residues for Allosteric Control in Hsp70"],"prefix":"10.1021","volume":"57","author":[{"given":"David","family":"Penkler","sequence":"first","affiliation":[{"name":"Research\rUnit in Bioinformatics (RUBi), Department of Biochemistry and Microbiology, Rhodes University, Grahamstown 6140, South Africa"}]},{"given":"\u00d6zge","family":"Sensoy","sequence":"additional","affiliation":[{"name":"School\rof Engineering and Natural Sciences, Istanbul Medipol University, Beykoz 34810, Istanbul, Turkey"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0557-6044","authenticated-orcid":true,"given":"Canan","family":"Atilgan","sequence":"additional","affiliation":[{"name":"Faculty\rof Engineering and Natural Sciences, Sabanci University, Tuzla 34956, Istanbul, Turkey"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6861-7849","authenticated-orcid":true,"given":"\u00d6zlem","family":"Tastan Bishop","sequence":"additional","affiliation":[{"name":"Research\rUnit in Bioinformatics (RUBi), Department of Biochemistry and Microbiology, Rhodes University, Grahamstown 6140, South Africa"}]}],"member":"316","published-online":{"date-parts":[[2017,6,12]]},"reference":[{"key":"ref1\/cit1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tibs.2013.08.001"},{"key":"ref2\/cit2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.96.10.5452"},{"key":"ref3\/cit3","doi-asserted-by":"publisher","DOI":"10.1016\/j.molcel.2005.12.017"},{"key":"ref4\/cit4","doi-asserted-by":"publisher","DOI":"10.1038\/ncomms9308"},{"key":"ref5\/cit5","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.271.19.11236"},{"key":"ref6\/cit6","doi-asserted-by":"publisher","DOI":"10.1007\/128_2012_323"},{"key":"ref7\/cit7","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2012.11.002"},{"key":"ref8\/cit8","doi-asserted-by":"publisher","DOI":"10.1126\/science.272.5268.1606"},{"key":"ref9\/cit9","doi-asserted-by":"publisher","DOI":"10.1016\/j.molcel.2012.09.023"},{"key":"ref10\/cit10","doi-asserted-by":"publisher","DOI":"10.1038\/nsmb.2583"},{"key":"ref11\/cit11","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0903503106"},{"key":"ref12\/cit12","doi-asserted-by":"publisher","DOI":"10.1016\/j.molcel.2007.02.020"},{"key":"ref13\/cit13","doi-asserted-by":"publisher","DOI":"10.1006\/jmbi.1998.2514"},{"key":"ref14\/cit14","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M609020200"},{"key":"ref15\/cit15","doi-asserted-by":"publisher","DOI":"10.1038\/msb.2010.65"},{"key":"ref16\/cit16","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1506692112"},{"key":"ref17\/cit17","doi-asserted-by":"publisher","DOI":"10.1515\/BC.2000.109"},{"key":"ref18\/cit18","doi-asserted-by":"publisher","DOI":"10.1006\/jmbi.1998.1815"},{"key":"ref19\/cit19","doi-asserted-by":"publisher","DOI":"10.1126\/science.8310296"},{"key":"ref20\/cit20","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1504625112"},{"key":"ref21\/cit21","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.270.28.16903"},{"key":"ref22\/cit22","doi-asserted-by":"publisher","DOI":"10.1038\/srep23474"},{"key":"ref23\/cit23","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pcbi.1003379"},{"key":"ref24\/cit24","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pcbi.1003279"},{"key":"ref25\/cit25","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0401313101"},{"key":"ref26\/cit26","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.93.20.10632"},{"key":"ref27\/cit27","doi-asserted-by":"publisher","DOI":"10.1016\/j.jmb.2015.02.004"},{"key":"ref28\/cit28","doi-asserted-by":"publisher","DOI":"10.1021\/ct1002169"},{"key":"ref29\/cit29","doi-asserted-by":"publisher","DOI":"10.1021\/ct200680g"},{"key":"ref30\/cit30","doi-asserted-by":"publisher","DOI":"10.1080\/07391102.2012.726190"},{"key":"ref31\/cit31","doi-asserted-by":"publisher","DOI":"10.1038\/nature10317"},{"key":"ref32\/cit32","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pcbi.1002844"},{"key":"ref33\/cit33","doi-asserted-by":"publisher","DOI":"10.1126\/science.291.5512.2429"},{"key":"ref34\/cit34","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pcbi.1003624"},{"key":"ref35\/cit35","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0143752"},{"key":"ref36\/cit36","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jcim.5b00755"},{"key":"ref37\/cit37","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pcbi.1000544"},{"key":"ref38\/cit38","doi-asserted-by":"publisher","DOI":"10.1016\/j.bpj.2010.05.020"},{"key":"ref39\/cit39","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pcbi.1002154"},{"key":"ref40\/cit40","doi-asserted-by":"publisher","DOI":"10.3109\/14756366.2014.979345"},{"key":"ref41\/cit41","doi-asserted-by":"publisher","DOI":"10.1039\/C5CP05107J"},{"key":"ref42\/cit42","doi-asserted-by":"publisher","DOI":"10.1016\/S0006-3495(01)76033-X"},{"key":"ref43\/cit43","doi-asserted-by":"publisher","DOI":"10.1063\/1.1288512"},{"key":"ref44\/cit44","doi-asserted-by":"publisher","DOI":"10.1103\/PhysRevLett.94.078102"},{"key":"ref45\/cit45","doi-asserted-by":"publisher","DOI":"10.1002\/prot.22843"},{"key":"ref46\/cit46","doi-asserted-by":"publisher","DOI":"10.1146\/annurev-biophys-050511-102305"},{"key":"ref47\/cit47","doi-asserted-by":"publisher","DOI":"10.1016\/j.bpj.2009.07.036"},{"key":"ref48\/cit48","doi-asserted-by":"publisher","DOI":"10.1107\/S0567739476001873"},{"key":"ref49\/cit49","doi-asserted-by":"publisher","DOI":"10.1002\/prot.20836"},{"key":"ref50\/cit50","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1097-0134(19990215)34:3<369::AID-PROT9>3.0.CO;2-F"},{"key":"ref51\/cit51","doi-asserted-by":"publisher","DOI":"10.1016\/0010-4655(95)00042-E"},{"key":"ref52\/cit52","doi-asserted-by":"publisher","DOI":"10.1093\/bioinformatics\/btt055"},{"key":"ref53\/cit53","doi-asserted-by":"publisher","DOI":"10.1016\/j.softx.2015.06.001"},{"key":"ref54\/cit54","doi-asserted-by":"publisher","DOI":"10.1021\/ct300400x"},{"key":"ref55\/cit55","doi-asserted-by":"publisher","DOI":"10.1021\/jp973084f"},{"key":"ref56\/cit56","doi-asserted-by":"publisher","DOI":"10.1002\/jcc.20065"},{"key":"ref57\/cit57","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkm423"},{"key":"ref58\/cit58","doi-asserted-by":"publisher","DOI":"10.1016\/j.bpj.2010.12.2217"},{"key":"ref59\/cit59","doi-asserted-by":"publisher","DOI":"10.1016\/j.molcel.2007.08.022"},{"key":"ref60\/cit60","doi-asserted-by":"publisher","DOI":"10.1016\/j.jmb.2011.07.001"},{"key":"ref61\/cit61","doi-asserted-by":"publisher","DOI":"10.1038\/emboj.2013.89"},{"key":"ref62\/cit62","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M600847200"},{"key":"ref63\/cit63","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.95.26.15229"},{"key":"ref64\/cit64","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.95.26.15223"},{"key":"ref65\/cit65","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M111.294728"},{"key":"ref66\/cit66","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/28.8.1665"},{"key":"ref67\/cit67","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkj046"},{"key":"ref68\/cit68","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0124563"},{"key":"ref69\/cit69","doi-asserted-by":"publisher","DOI":"10.1002\/prot.24925"},{"key":"ref70\/cit70","doi-asserted-by":"publisher","DOI":"10.1038\/nsb0597-342"},{"key":"ref71\/cit71","doi-asserted-by":"publisher","DOI":"10.1016\/j.molcel.2010.03.010"},{"key":"ref72\/cit72","doi-asserted-by":"publisher","DOI":"10.1016\/j.molcel.2010.07.012"},{"key":"ref73\/cit73","doi-asserted-by":"publisher","DOI":"10.1038\/76819"},{"key":"ref74\/cit74","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M400921200"},{"key":"ref75\/cit75","doi-asserted-by":"publisher","DOI":"10.1021\/bi034126v"},{"key":"ref76\/cit76","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M114.623371"},{"key":"ref77\/cit77","doi-asserted-by":"publisher","DOI":"10.1146\/annurev-biophys-050511-102319"}],"container-title":["Journal of Chemical Information and Modeling"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acs.jcim.6b00775","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,4,13]],"date-time":"2023-04-13T22:11:28Z","timestamp":1681423888000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/acs.jcim.6b00775"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,6,12]]},"references-count":77,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2017,6,26]]}},"alternative-id":["10.1021\/acs.jcim.6b00775"],"URL":"https:\/\/doi.org\/10.1021\/acs.jcim.6b00775","relation":{},"ISSN":["1549-9596","1549-960X"],"issn-type":[{"value":"1549-9596","type":"print"},{"value":"1549-960X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,6,12]]}}}