{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,23]],"date-time":"2025-10-23T16:44:54Z","timestamp":1761237894601},"reference-count":31,"publisher":"American Chemical Society (ACS)","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Chem. Inf. Model."],"published-print":{"date-parts":[[2012,5,25]]},"DOI":"10.1021\/ci300094e","type":"journal-article","created":{"date-parts":[[2012,4,24]],"date-time":"2012-04-24T23:23:19Z","timestamp":1335309799000},"page":"1376-1390","source":"Crossref","is-referenced-by-count":18,"title":["Toward the Identification of a Reliable 3D QSAR Pharmacophore Model for the CCK2 Receptor Antagonism"],"prefix":"10.1021","volume":"52","author":[{"given":"Amit K.","family":"Gupta","sequence":"first","affiliation":[{"name":"Medicinal and Process Chemistry Division, C.S.I.R.-Central Drug Research Institute, Lucknow 226001,\rIndia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kanika","family":"Varshney","sequence":"additional","affiliation":[{"name":"Medicinal and Process Chemistry Division, C.S.I.R.-Central Drug Research Institute, Lucknow 226001,\rIndia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anil K.","family":"Saxena","sequence":"additional","affiliation":[{"name":"Medicinal and Process Chemistry Division, C.S.I.R.-Central Drug Research Institute, Lucknow 226001,\rIndia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"316","published-online":{"date-parts":[[2012,5,4]]},"reference":[{"key":"ref1\/cit1a","first-page":"1377","volume":"57","author":"Reubi J. C.","year":"1997","journal-title":"Cancer Res."},{"key":"ref1\/cit1b","doi-asserted-by":"crossref","first-page":"1075","DOI":"10.1023\/B:DDAS.0000037790.11724.70","volume":"49","author":"Konturek P. C.","year":"2004","journal-title":"Dig. Dis. Sci."},{"key":"ref1\/cit1c","doi-asserted-by":"crossref","first-page":"559","DOI":"10.1002\/med.10042","volume":"23","author":"Herranz R.","year":"2003","journal-title":"Med. Res. Rev."},{"key":"ref2\/cit2","doi-asserted-by":"crossref","first-page":"338","DOI":"10.1038\/sj.bjp.0706053","volume":"144","author":"Colucci R.","year":"2005","journal-title":"Br. J. Pharmacol."},{"key":"ref3\/cit3","doi-asserted-by":"crossref","first-page":"8164","DOI":"10.1016\/S0021-9258(18)53076-3","volume":"268","author":"Lee Y. M.","year":"1993","journal-title":"J. Biol. Chem."},{"key":"ref4\/cit4","doi-asserted-by":"crossref","first-page":"513","DOI":"10.1111\/j.1432-1033.1993.tb18061.x","volume":"215","author":"Poirot S. S.","year":"1993","journal-title":"Eur. J. Biochem."},{"key":"ref5\/cit5","first-page":"628","volume":"269","author":"Wank S. A.","year":"1995","journal-title":"Am. J. Physiol."},{"key":"ref6\/cit6","doi-asserted-by":"crossref","first-page":"731","DOI":"10.1016\/0196-9781(94)90104-X","volume":"15","author":"Crawley J. N.","year":"1994","journal-title":"Peptides"},{"key":"ref7\/cit7","doi-asserted-by":"crossref","first-page":"445","DOI":"10.1517\/13543776.11.3.445","volume":"11","author":"McDonald I. M.","year":"2001","journal-title":"Expert Opin. Ther. Pat."},{"key":"ref8\/cit8","doi-asserted-by":"crossref","first-page":"583","DOI":"10.1016\/j.coph.2007.09.011","volume":"7","author":"Berna M. J.","year":"2007","journal-title":"Curr. Opin. Pharmacol."},{"key":"ref9\/cit9","doi-asserted-by":"crossref","first-page":"6376","DOI":"10.1016\/j.bmcl.2009.09.065","volume":"19","author":"Pippel M.","year":"2009","journal-title":"Bioorg. Med. Chem. Lett."},{"key":"ref10\/cit10","doi-asserted-by":"crossref","first-page":"3101","DOI":"10.1021\/jm070139l","volume":"50","author":"McDonald I. M.","year":"2007","journal-title":"J. Med. Chem."},{"key":"ref11\/cit11","doi-asserted-by":"crossref","first-page":"1510","DOI":"10.1021\/ci100180e","volume":"50","author":"Gupta A. K.","year":"2010","journal-title":"J. Chem. Inf. Model."},{"key":"ref12\/cit12","doi-asserted-by":"crossref","first-page":"409","DOI":"10.1016\/j.jmgm.2008.07.003","volume":"27","author":"Kaur K.","year":"2008","journal-title":"J. Mol. Graphics Modell."},{"key":"ref13\/cit13","doi-asserted-by":"crossref","first-page":"1934","DOI":"10.1021\/ci050257m","volume":"45","author":"Chopra M.","year":"2005","journal-title":"J. Chem. Inf. Model."},{"key":"ref14\/cit14","doi-asserted-by":"crossref","first-page":"6373","DOI":"10.1016\/j.bmcl.2009.09.064","volume":"19","author":"Pippel M.","year":"2009","journal-title":"Bioorg. Med. Chem. Lett."},{"key":"ref15\/cit15","doi-asserted-by":"crossref","first-page":"2974","DOI":"10.1016\/j.bmc.2007.12.047","volume":"16","author":"John Spencer J.","year":"2008","journal-title":"Bioorg. Med. Chem."},{"key":"ref16\/cit16","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1016\/S0968-0896(99)00246-1","volume":"8","author":"Kim S. G.","year":"2000","journal-title":"Bioorg. Med. Chem."},{"key":"ref18\/cit18","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1002\/jcc.540160205","volume":"16","author":"Smellie A.","year":"1995","journal-title":"J. Comput. Chem."},{"key":"ref19\/cit19","unstructured":"Gund, P.InPharmacophore Perception, Development, and Drug Design;Gunner, O. F., Ed.International University Line:California, U.S.A. 2000; pp3\u201311."},{"key":"ref20\/cit20","volume-title":"The principle of experimentation, illustrated by a psycho-physical experiment. the design of experiments","author":"Fischer R.","year":"1966","edition":"8"},{"key":"ref21\/cit21","doi-asserted-by":"crossref","first-page":"4779","DOI":"10.1016\/j.bmcl.2010.06.120","volume":"20","author":"Gupta A. K.","year":"2010","journal-title":"Bioorg. Med. Chem. Lett."},{"key":"ref22\/cit22","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1016\/0014-2999(95)00676-1","volume":"296","author":"Jagerschmidt A.","year":"1996","journal-title":"Eur. J. Pharmacol."},{"key":"ref23\/cit23","doi-asserted-by":"crossref","first-page":"381","DOI":"10.1007\/BF01886795","volume":"14","author":"Joseph M. P.","year":"1995","journal-title":"J. Protein. Chem."},{"key":"ref24\/cit24","doi-asserted-by":"crossref","first-page":"680","DOI":"10.1124\/mol.105.019992","volume":"69","author":"Foucaud M.","year":"2006","journal-title":"Mol. Pharmacol."},{"key":"ref25\/cit25","doi-asserted-by":"crossref","first-page":"508","DOI":"10.1529\/biophysj.106.082313","volume":"91","author":"Forrest L. R.","year":"2006","journal-title":"Biophys. J."},{"key":"ref26\/cit26","unstructured":"Swiss-prot.http:\/\/www.uniprot.org\/uniprot\/p32239(accessed December 12, 2011)."},{"key":"ref27\/cit27","unstructured":"Prime, version 2.2;Schr\u00f6dinger, LLC:New York, NY, 2010."},{"key":"ref28\/cit28","unstructured":"Schr\u00f6dinger, version 9.1;Schrodinger, LLC:New York, 2005."},{"key":"ref29\/cit29","unstructured":"MacroModel, version 9.8;Schr\u00f6dinger, LLC:New York, NY, 2010."},{"key":"ref30\/cit30","unstructured":"The PyMOL Molecular Graphics System, version 1.3r1;Schrodinger, LLC:Portland, OR, 2010."}],"container-title":["Journal of Chemical Information and Modeling"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/ci300094e","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,4,17]],"date-time":"2023-04-17T13:18:34Z","timestamp":1681737514000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/ci300094e"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,5,4]]},"references-count":31,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2012,5,25]]}},"alternative-id":["10.1021\/ci300094e"],"URL":"https:\/\/doi.org\/10.1021\/ci300094e","relation":{},"ISSN":["1549-9596","1549-960X"],"issn-type":[{"value":"1549-9596","type":"print"},{"value":"1549-960X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,5,4]]}}}