{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,23]],"date-time":"2025-10-23T16:39:15Z","timestamp":1761237555406},"reference-count":21,"publisher":"American Chemical Society (ACS)","issue":"8","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Chem. Inf. Model."],"published-print":{"date-parts":[[2008,8,1]]},"DOI":"10.1021\/ci800051h","type":"journal-article","created":{"date-parts":[[2008,7,19]],"date-time":"2008-07-19T08:01:03Z","timestamp":1216454463000},"page":"1558-1570","source":"Crossref","is-referenced-by-count":25,"title":["Evolving Interpretable Structure\u2212Activity Relationship Models. 2. Using Multiobjective Optimization To Derive Multiple Models"],"prefix":"10.1021","volume":"48","author":[{"given":"Kristian","family":"Birchall","sequence":"first","affiliation":[{"name":"Department of Information Studies, University of Sheffield, Regent Court, 211 Portobello Street, Sheffield S1 4DP, United Kingdom, and GlaxoSmithKline, Medicines Research Centre, Gunnels Wood Road, Stevenage SG1 2NY, United Kingdom"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Valerie J.","family":"Gillet","sequence":"additional","affiliation":[{"name":"Department of Information Studies, University of Sheffield, Regent Court, 211 Portobello Street, Sheffield S1 4DP, United Kingdom, and GlaxoSmithKline, Medicines Research Centre, Gunnels Wood Road, Stevenage SG1 2NY, United Kingdom"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gavin","family":"Harper","sequence":"additional","affiliation":[{"name":"Department of Information Studies, University of Sheffield, Regent Court, 211 Portobello Street, Sheffield S1 4DP, United Kingdom, and GlaxoSmithKline, Medicines Research Centre, Gunnels Wood Road, Stevenage SG1 2NY, United Kingdom"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stephen D.","family":"Pickett","sequence":"additional","affiliation":[{"name":"Department of Information Studies, University of Sheffield, Regent Court, 211 Portobello Street, Sheffield S1 4DP, United Kingdom, and GlaxoSmithKline, Medicines Research Centre, Gunnels Wood Road, Stevenage SG1 2NY, United Kingdom"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"316","published-online":{"date-parts":[[2008,7,19]]},"reference":[{"key":"ref1\/cit1","doi-asserted-by":"crossref","first-page":"694","DOI":"10.1016\/j.drudis.2006.06.006","volume":"11","author":"Harper G.","year":"2006","journal-title":"Drug Discovery Today"},{"key":"ref2\/cit2","doi-asserted-by":"crossref","first-page":"1122","DOI":"10.1021\/ci049732r","volume":"45","author":"Saeh J. C.","year":"2005","journal-title":"J. Chem. Inf. Model."},{"key":"ref3\/cit3","doi-asserted-by":"crossref","first-page":"469","DOI":"10.1021\/ci025586i","volume":"43","author":"Wilton D.","year":"2003","journal-title":"J. Chem. Inf. Comput. Sci."},{"key":"ref4\/cit4","doi-asserted-by":"crossref","first-page":"682","DOI":"10.1177\/1087057105281365","volume":"10","author":"Rogers D.","year":"2005","journal-title":"J. Biomol. Screening"},{"key":"ref5\/cit5","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1021\/ci600332j","volume":"47","author":"Bruce C. L.","year":"2007","journal-title":"J. Chem. Inf. Model."},{"key":"ref6\/cit6","doi-asserted-by":"crossref","first-page":"1543","DOI":"10.1021\/ci8000502","volume":"48","author":"Birchall K.","year":"2008","journal-title":"J. Chem. Inf. Model."},{"key":"ref7\/cit7","volume-title":"Information retrieval","author":"van Rijsbergen C. J.","year":"1979"},{"key":"ref8\/cit8","volume-title":"Daylight theory manual 4.82","author":"James C. A.","year":"2003"},{"key":"ref9\/cit9","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1145\/1143844.1143874","volume-title":"Proceedings of the 23rd International Conference on Machine Learning","author":"Davis J.","year":"2006"},{"key":"ref10\/cit10","doi-asserted-by":"crossref","first-page":"2534","DOI":"10.1021\/jm049092j","volume":"48","author":"Triballeau N.","year":"2005","journal-title":"J. Med. Chem."},{"key":"ref11\/cit11","doi-asserted-by":"crossref","first-page":"2145","DOI":"10.1021\/ci049860f","volume":"44","author":"Harper G.","year":"2004","journal-title":"J. Chem. Inf. Comput. Sci."},{"key":"ref12\/cit12","doi-asserted-by":"crossref","first-page":"503","DOI":"10.1021\/ci050347r","volume":"46","author":"Barker E. J.","year":"2006","journal-title":"J. Chem. Inf. Model."},{"key":"ref13\/cit13","doi-asserted-by":"crossref","first-page":"338","DOI":"10.1021\/ci025592e","volume":"43","author":"Gillet V. J.","year":"2003","journal-title":"J. Chem. Inf. Comput. Sci."},{"key":"ref14\/cit14","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1109\/3468.650319","volume":"28","author":"Fonseca C. M.","year":"1998","journal-title":"IEEE Trans. Systems, Man, Cybernetics"},{"key":"ref15\/cit15","volume-title":"Genetic algorithms in search, optimization and machine learning","author":"Goldberg D. E.","year":"1989"},{"key":"ref16\/cit16","doi-asserted-by":"crossref","first-page":"747","DOI":"10.1021\/ci9803381","volume":"39","author":"Butina D.","year":"1999","journal-title":"J. Chem. Inf. Comput. Sci."},{"key":"ref17\/cit17","unstructured":"MDL Information Systems Inc. 2440 Camino Ramon, Suite 300, San Ramon, CA 94583."},{"key":"ref18\/cit18","doi-asserted-by":"crossref","first-page":"3256","DOI":"10.1039\/b409865j","volume":"2","author":"Hert J.","year":"2004","journal-title":"Org. Biomol. Chem."},{"key":"ref19\/cit19","doi-asserted-by":"crossref","first-page":"463","DOI":"10.1038\/nature04710","volume":"440","author":"Sanguinetti M. C.","year":"2006","journal-title":"Nature"},{"key":"ref20\/cit20","doi-asserted-by":"crossref","first-page":"392","DOI":"10.1021\/ci050308f","volume":"46","author":"Song M.","year":"2006","journal-title":"J. Chem. Inf. Model."},{"key":"ref21\/cit21","doi-asserted-by":"crossref","first-page":"2307","DOI":"10.1016\/j.bmc.2004.02.003","volume":"12","author":"Aronov A. M.","year":"2004","journal-title":"Bioorg. Med. Chem."}],"container-title":["Journal of Chemical Information and Modeling"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/ci800051h","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,3,21]],"date-time":"2023-03-21T15:59:13Z","timestamp":1679414353000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/ci800051h"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,7,19]]},"references-count":21,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2008,8,1]]}},"alternative-id":["10.1021\/ci800051h"],"URL":"https:\/\/doi.org\/10.1021\/ci800051h","relation":{},"ISSN":["1549-9596","1549-960X"],"issn-type":[{"value":"1549-9596","type":"print"},{"value":"1549-960X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2008,7,19]]}}}