{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,21]],"date-time":"2026-08-21T09:39:46Z","timestamp":1787305186937,"version":"build-2736575974"},"reference-count":74,"publisher":"American Chemical Society (ACS)","issue":"14","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Anal. Chem."],"published-print":{"date-parts":[[2001,7,1]]},"DOI":"10.1021\/ac010042l","type":"journal-article","created":{"date-parts":[[2002,7,26]],"date-time":"2002-07-26T04:39:39Z","timestamp":1027658379000},"page":"3263-3273","source":"Crossref","is-referenced-by-count":16,"title":["Matrix-Assisted Laser Desorption\/Ionization Mass Spectrometry for Locating Abasic Sites and Determining the Rates of Enzymatic Hydrolysis of Model Oligodeoxynucleotides"],"prefix":"10.1021","volume":"73","author":[{"given":"Li-Kang","family":"Zhang","sequence":"first","affiliation":[{"name":"Department of Chemistry, Washington University, 1 Brookings Drive, St. Louis, Missouri 63130"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Don","family":"Rempel","sequence":"additional","affiliation":[{"name":"Department of Chemistry, Washington University, 1 Brookings Drive, St. Louis, Missouri 63130"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael L.","family":"Gross","sequence":"additional","affiliation":[{"name":"Department of Chemistry, Washington University, 1 Brookings Drive, St. Louis, Missouri 63130"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2001,6,19]]},"reference":[{"key":"ac010042lb00001\/ac010042lb00001_1","first-page":"336","volume":"15","author":"Limbach P. A.","year":"1997","journal-title":"Mass Spectrom. Rev."},{"key":"ac010042lb00002\/ac010042lb00002_1","first-page":"138","volume":"15","author":"Nordhoff E.","year":"1997","journal-title":"Mass Spectrom. Rev."},{"key":"ac010042lb00003\/ac010042lb00003_1","doi-asserted-by":"crossref","first-page":"1203","DOI":"10.1016\/0731-7085(95)01534-R","volume":"13","author":"Schuette J. M.","year":"1995","journal-title":"J. Pharm. Biomed. Anal."},{"key":"ac010042lb00004\/ac010042lb00004_1","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1515\/REVAC.1998.17.1.1","volume":"17","author":"Muddiman D. C.","year":"1998","journal-title":"Rev. Anal. Chem."},{"key":"ac010042lb00005\/ac010042lb00005_1","doi-asserted-by":"crossref","first-page":"1964","DOI":"10.1093\/nar\/25.10.1957","volume":"25","author":"Hahner S.","year":"1997","journal-title":"Nucleic Acids Res."},{"key":"ac010042lb00006\/ac010042lb00006_1","doi-asserted-by":"crossref","first-page":"6129","DOI":"10.1073\/pnas.78.10.6126","volume":"78","author":"Randerath K.","year":"1981","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"ac010042lb00007\/ac010042lb00007_1","first-page":"2232","volume":"73","author":"Sun H. B.","year":"2001","journal-title":"Anal. Chem."},{"key":"ac010042lb00008\/ac010042lb00008_1","doi-asserted-by":"crossref","first-page":"2930","DOI":"10.1021\/ac00113a029","volume":"67","author":"Stemmler E. A.","year":"1995","journal-title":"Anal. Chem."},{"key":"ac010042lb00009\/ac010042lb00009_1","first-page":"496","volume":"165","author":"Vollmer D.","year":"1997","journal-title":"Int. J. Mass Spectrom. Ion Processes"},{"key":"ac010042lb00010\/ac010042lb00010_1","first-page":"691","volume":"9","author":"Wang Z.","year":"1998","journal-title":"J. Am. Soc. Mass Spectrom."},{"key":"ac010042lb00011\/ac010042lb00011_1","first-page":"338","volume":"10","author":"Wang Y.","year":"1999","journal-title":"J. Am. Soc. Mass Spectrom."},{"key":"ac010042lb00012\/ac010042lb00012_1","doi-asserted-by":"crossref","first-page":"3196","DOI":"10.1093\/nar\/21.14.3191","volume":"21","author":"Pieles U.","year":"1993","journal-title":"Nucleic Acids Res."},{"key":"ac010042lb00013\/ac010042lb00013_1","doi-asserted-by":"crossref","first-page":"3412","DOI":"10.1021\/ac9602985","volume":"68","author":"Keough T.","year":"1996","journal-title":"Anal. Chem."},{"key":"ac010042lb00014\/ac010042lb00014_1","doi-asserted-by":"crossref","first-page":"4164","DOI":"10.1093\/nar\/25.20.4162","volume":"25","author":"Tamura T.","year":"1997","journal-title":"Nucleic Acids Res."},{"key":"ac010042lb00015\/ac010042lb00015_1","first-page":"138","volume":"263","author":"Wu H.","year":"1998","journal-title":"Anal. Biochem."},{"key":"ac010042lb00016\/ac010042lb00016_1","first-page":"135","volume":"287","author":"Wu H.","year":"2000","journal-title":"Anal. Biochem."},{"key":"ac010042lb00017\/ac010042lb00017_1","first-page":"352","volume":"290","author":"Wu H.","year":"2001","journal-title":"Anal. Biochem."},{"key":"ac010042lb00018\/ac010042lb00018_1","first-page":"865","volume":"11","author":"Zhang L. K.","year":"2000","journal-title":"J. Am. Soc. Mass Spectrom."},{"key":"ac010042lb00019\/ac010042lb00019_1","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1021\/ja992800j","volume":"122","author":"Asara J. M.","year":"2000","journal-title":"J. Am. Chem. Soc."},{"key":"ac010042lb00020\/ac010042lb00020_1","doi-asserted-by":"crossref","first-page":"466","DOI":"10.1021\/tx980235c","volume":"12","author":"Tretyakova N. Y.","year":"1999","journal-title":"Chem. Res. Toxicol."},{"key":"ac010042lb00021\/ac010042lb00021_1","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1016\/S0027-5107(99)00004-4","volume":"424","author":"Cadet J.","year":"1999","journal-title":"Mutat. Res."},{"key":"ac010042lb00022\/ac010042lb00022_1","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1016\/S0300-9084(00)00347-3","volume":"82","author":"Gasparutto D.","year":"2000","journal-title":"Biochimie"},{"key":"ac010042lb00023\/ac010042lb00023_1","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1021\/jo00175a011","volume":"49","author":"Romieu A.","year":"1984","journal-title":"Eur. J. Org. Chem."},{"key":"ac010042lb00024\/ac010042lb00024_1","doi-asserted-by":"crossref","first-page":"3344","DOI":"10.1021\/bi981982b","volume":"38","author":"D'Ham C.","year":"1999","journal-title":"Biochemistry"},{"key":"ac010042lb00025\/ac010042lb00025_1","doi-asserted-by":"crossref","first-page":"10942","DOI":"10.1073\/pnas.94.20.10937","volume":"94","author":"Cavalieri E. L.","year":"1997","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"ac010042lb00026\/ac010042lb00026_1","first-page":"347","volume":"38","author":"Loeb L. A.","year":"1986","journal-title":"Basic Life Sci."},{"key":"ac010042lb00027\/ac010042lb00027_1","first-page":"230","volume":"20","author":"Loeb L. A.","year":"1986","journal-title":"Annu. Rev. Genet."},{"key":"ac010042lb00028\/ac010042lb00028_1","first-page":"6605","volume":"90","author":"Zhou W.","year":"1993","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"ac010042lb00029\/ac010042lb00029_1","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1016\/0921-8777(90)90004-O","volume":"236","author":"Doetsch P. W.","year":"1990","journal-title":"Mutat. Res."},{"key":"ac010042lb00030\/ac010042lb00030_1","first-page":"110","volume":"302","author":"Doetsch P. W.","year":"1999","journal-title":"NATO ASI Ser., Ser. A"},{"key":"ac010042lb00031\/ac010042lb00031_1","doi-asserted-by":"crossref","first-page":"354","DOI":"10.1111\/j.1749-6632.1994.tb52849.x","volume":"726","author":"Zhou W.","year":"1994","journal-title":"Ann. N.Y. Acad. Sci."},{"key":"ac010042lb00032\/ac010042lb00032_1","doi-asserted-by":"crossref","first-page":"16386","DOI":"10.1016\/S0021-9258(18)55309-6","volume":"266","author":"Nutter L. M.","year":"1991","journal-title":"J. Biol. Chem."},{"key":"ac010042lb00033\/ac010042lb00033_1","first-page":"102","volume":"10","author":"Smith L. A.","year":"1983","journal-title":"Biomed. Mass Spectrom."},{"key":"ac010042lb00034\/ac010042lb00034_1","doi-asserted-by":"crossref","first-page":"479","DOI":"10.1093\/nar\/25.3.474","volume":"25","author":"Karakaya A.","year":"1997","journal-title":"Nucleic Acids Res."},{"key":"ac010042lb00035\/ac010042lb00035_1","first-page":"364","volume":"329","author":"Simpson F. B.","year":"2000","journal-title":"Mass Spectrom. Biol. Med."},{"key":"ac010042lb00036\/ac010042lb00036_1","doi-asserted-by":"crossref","first-page":"644","DOI":"10.1016\/S0968-0896(97)00020-5","volume":"5","author":"Northrop D. B.","year":"1997","journal-title":"Bioorg. Med. Chem."},{"key":"ac010042lb00037\/ac010042lb00037_1","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1006\/abio.1998.2569","volume":"258","author":"Bentzley C. M.","year":"1998","journal-title":"Anal. Biochem."},{"key":"ac010042lb00038\/ac010042lb00038_1","volume-title":"Nucleases","author":"Linn S. M.","year":"1993","edition":"2"},{"key":"ac010042lb00039\/ac010042lb00039_1","doi-asserted-by":"crossref","first-page":"9103","DOI":"10.1021\/bi00449a021","volume":"28","author":"Nordlund T. M.","year":"1989","journal-title":"Biochemistry"},{"key":"ac010042lb00040\/ac010042lb00040_1","doi-asserted-by":"crossref","first-page":"626","DOI":"10.1093\/nar\/21.3.621","volume":"21","author":"Weinfeld M.","year":"1993","journal-title":"Nucleic Acids Res."},{"key":"ac010042lb00041\/ac010042lb00041_1","doi-asserted-by":"crossref","first-page":"26","DOI":"10.2307\/3578166","volume":"126","author":"Maccubbin A.","year":"1991","journal-title":"Radiat. Res."},{"key":"ac010042lb00042\/ac010042lb00042_1","first-page":"1924","volume":"66","author":"Wang B. H.","year":"1994","journal-title":"Anal. Chem."},{"key":"ac010042lb00043\/ac010042lb00043_1","volume-title":"The Art of Scientific Computing","author":"Press W. H.","year":"1992","edition":"2"},{"key":"ac010042lb00044\/ac010042lb00044_1","volume-title":"Mathcad 8 Professional","author":"MathSoft","year":"1998"},{"key":"ac010042lb00045\/ac010042lb00045_1","doi-asserted-by":"crossref","first-page":"1902","DOI":"10.1093\/nar\/22.10.1897","volume":"22","author":"Takeshita M.","year":"1994","journal-title":"Nucleic Acids Res."},{"key":"ac010042lb00046\/ac010042lb00046_1","doi-asserted-by":"crossref","first-page":"10179","DOI":"10.1016\/S0021-9258(18)61093-2","volume":"262","author":"Takeshita M.","year":"1987","journal-title":"J. Biol. Chem."},{"key":"ac010042lb00047\/ac010042lb00047_1","doi-asserted-by":"crossref","first-page":"931","DOI":"10.1021\/bi00403a014","volume":"27","author":"Kalnik M. W.","year":"1988","journal-title":"J. Biochemistry"},{"key":"ac010042lb00048\/ac010042lb00048_1","doi-asserted-by":"crossref","first-page":"3745","DOI":"10.1093\/nar\/17.10.3735","volume":"17","author":"Weinfeld M.","year":"1989","journal-title":"Nucleic Acids Res."},{"key":"ac010042lb00049\/ac010042lb00049_1","first-page":"257","volume":"26","author":"Yum Y. N.","year":"1993","journal-title":"Han'guk Saenghwa Hakhoechi"},{"key":"ac010042lb00050\/ac010042lb00050_1","first-page":"263","volume":"26","author":"Yum Y. N.","year":"1993","journal-title":"Han'guk Saenghwa Hakhoechi"},{"key":"ac010042lb00051\/ac010042lb00051_1","doi-asserted-by":"crossref","first-page":"8659","DOI":"10.1016\/S0021-9258(19)75271-5","volume":"252","author":"Pritchard A. E.","year":"1977","journal-title":"J. Biol. Chem."},{"key":"ac010042lb00052\/ac010042lb00052_1","first-page":"1024","volume":"27","author":"Bourdat A.-G.","year":"1999","journal-title":"Nucleic Acids Res."},{"key":"ac010042lb00053\/ac010042lb00053_1","volume-title":"Chemical Kinetics and Dynamics","author":"Steinfeld J. I.","year":"1995"},{"key":"ac010042lb00054\/ac010042lb00054_1","doi-asserted-by":"crossref","first-page":"1301","DOI":"10.1021\/cr960435y","volume":"97","author":"Mader M. M.","year":"1997","journal-title":"Chem. Rev."},{"key":"ac010042lb00055\/ac010042lb00055_1","doi-asserted-by":"crossref","first-page":"304","DOI":"10.1002\/ange.19770890505","volume":"89","author":"Albery W. J.","year":"1977","journal-title":"Angew. Chem."},{"key":"ac010042lb00056\/ac010042lb00056_1","volume-title":"Biochemistry","author":"Stryer L.","year":"1996","edition":"4"},{"key":"ac010042lb00057\/ac010042lb00057_1","doi-asserted-by":"crossref","first-page":"364","DOI":"10.1021\/ed073p359","volume":"73","author":"Kahley M. J.","year":"1996","journal-title":"J. Chem. Educ."},{"key":"ac010042lb00058\/ac010042lb00058_1","doi-asserted-by":"crossref","first-page":"118","DOI":"10.1016\/0040-6031(95)02628-2","volume":"273","author":"Reich L.","year":"1996","journal-title":"Thermochim. Acta"},{"key":"ac010042lb00059\/ac010042lb00059_1","doi-asserted-by":"crossref","first-page":"1081","DOI":"10.1023\/A:1018964227041","volume":"11","author":"Teraoka R.","year":"1994","journal-title":"Pharm. Res."},{"key":"ac010042lb00060\/ac010042lb00060_1","first-page":"201","volume":"28","author":"Aboul-Seoud A.","year":"1993","journal-title":"Chem. Eng. World"},{"key":"ac010042lb00061\/ac010042lb00061_1","doi-asserted-by":"crossref","first-page":"106","DOI":"10.1016\/0097-8485(93)80035-C","volume":"17","author":"Chrastil J.","year":"1993","journal-title":"Comput. Chem."},{"key":"ac010042lb00062\/ac010042lb00062_1","doi-asserted-by":"crossref","first-page":"292","DOI":"10.1016\/0097-8485(88)80002-0","volume":"12","author":"Chrastil J.","year":"1988","journal-title":"Comput. Chem."},{"key":"ac010042lb00063\/ac010042lb00063_1","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1002\/(SICI)1097-4601(1998)30:2<151::AID-KIN7>3.0.CO;2-R","volume":"30","author":"Tadi M.","year":"1998","journal-title":"Int. J. Chem. Kinet."},{"key":"ac010042lb00064\/ac010042lb00064_1","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1021\/a1960002k","volume":"68","author":"Mottola H. A.","year":"1996","journal-title":"Anal. Chem."},{"key":"ac010042lb00065\/ac010042lb00065_1","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1021\/a1000004b","volume":"72","author":"Crouch S. R.","year":"2000","journal-title":"Anal. Chem."},{"key":"ac010042lb00066\/ac010042lb00066_1","doi-asserted-by":"crossref","first-page":"106R","DOI":"10.1021\/a1980005s","volume":"70","author":"Crouch S. R.","year":"1998","journal-title":"Anal. Chem."},{"key":"ac010042lb00067\/ac010042lb00067_1","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1016\/S0968-0004(97)01062-1","volume":"22","author":"Dang Q.","year":"1997","journal-title":"Trends Biochem. Sci."},{"key":"ac010042lb00068\/ac010042lb00068_1","doi-asserted-by":"crossref","first-page":"387","DOI":"10.1042\/bj2580381","volume":"258","author":"Zimmerle C. T.","year":"1989","journal-title":"Biochem. J."},{"key":"ac010042lb00069\/ac010042lb00069_1","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1016\/0003-2697(83)90660-7","volume":"130","author":"Barshop B. A.","year":"1983","journal-title":"Anal. Biochem."},{"key":"ac010042lb00070\/ac010042lb00070_1","volume-title":"Methods and Applications of Linear Models:\u2009 Regression and the Analysis of Variance","author":"Hocking R. R.","year":"1996"},{"key":"ac010042lb00071\/ac010042lb00071_1","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1006\/abio.1994.1539","volume":"223","author":"Gutheil W. G.","year":"1994","journal-title":"Anal. Biochem."},{"key":"ac010042lb00072\/ac010042lb00072_1","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1016\/0005-2787(68)90180-9","volume":"155","author":"Bernardi A.","year":"1968","journal-title":"Biochim. Biophys. Acta"},{"key":"ac010042lb00073\/ac010042lb00073_1","doi-asserted-by":"crossref","first-page":"370","DOI":"10.1016\/0005-2787(68)90180-9","volume":"155","author":"Bernardi A.","year":"1968","journal-title":"Biochim. Biophys. Acta"},{"key":"ac010042lb00074\/ac010042lb00074_1","first-page":"105","volume":"18","author":"Pluskal M. G.","year":"2000","journal-title":"Usa Nat. Biotechnol."}],"container-title":["Analytical Chemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/ac010042l","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,10,17]],"date-time":"2021-10-17T09:23:43Z","timestamp":1634462623000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/ac010042l"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2001,6,19]]},"references-count":74,"journal-issue":{"issue":"14","published-print":{"date-parts":[[2001,7,1]]}},"alternative-id":["10.1021\/ac010042l"],"URL":"https:\/\/doi.org\/10.1021\/ac010042l","relation":{},"ISSN":["0003-2700","1520-6882"],"issn-type":[{"value":"0003-2700","type":"print"},{"value":"1520-6882","type":"electronic"}],"subject":[],"published":{"date-parts":[[2001,6,19]]}}}