{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,6]],"date-time":"2026-11-06T09:07:49Z","timestamp":1793956069926,"version":"4.8.0"},"reference-count":15,"publisher":"American Chemical Society (ACS)","issue":"13","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Anal. Chem."],"published-print":{"date-parts":[[2003,7,1]]},"DOI":"10.1021\/ac020361s","type":"journal-article","created":{"date-parts":[[2003,6,30]],"date-time":"2003-06-30T04:29:45Z","timestamp":1056947385000},"page":"3019-3030","source":"Crossref","is-referenced-by-count":5009,"title":["Strategies for the Assessment of Matrix Effect in Quantitative Bioanalytical Methods Based on HPLC\u2212MS\/MS"],"prefix":"10.1021","volume":"75","author":[{"given":"B. K.","family":"Matuszewski","sequence":"first","affiliation":[{"name":"Merck Research Laboratories, West Point, Pennsylvania 19486"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M. L.","family":"Constanzer","sequence":"additional","affiliation":[{"name":"Merck Research Laboratories, West Point, Pennsylvania 19486"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C. M.","family":"Chavez-Eng","sequence":"additional","affiliation":[{"name":"Merck Research Laboratories, West Point, Pennsylvania 19486"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2003,6,4]]},"reference":[{"key":"ac020361sb00001\/ac020361sb00001_1","first-page":"357","volume":"18","author":"Fu I.","year":"1998","journal-title":"J. Pharm. Biomed. Anal."},{"issue":"5","key":"ac020361sb00002\/ac020361sb00002_1","doi-asserted-by":"crossref","first-page":"889","DOI":"10.1021\/ac971078+","volume":"70","author":"Matuszewski B. K.","year":"1998","journal-title":"Anal. Chem."},{"key":"ac020361sb00003\/ac020361sb00003_1","first-page":"207","volume":"2","author":"Clarke S. D.","year":"1996","journal-title":"Pharm. Sci."},{"key":"ac020361sb00004\/ac020361sb00004_1","first-page":"129","volume":"693","author":"Constanzer M. L.","year":"1997","journal-title":"J. Chromatogr., B"},{"key":"ac020361sb00005\/ac020361sb00005_1","doi-asserted-by":"crossref","first-page":"208","DOI":"10.1016\/S0378-4347(98)00317-X","volume":"716","author":"Matuszewski B. K.","year":"1998","journal-title":"J. Chromatogr., B"},{"key":"ac020361sb00006\/ac020361sb00006_1","first-page":"106","volume":"13","author":"Jemal M.","year":"1999","journal-title":"Rapid Commun. Mass Spectrom."},{"key":"ac020361sb00007\/ac020361sb00007_1","doi-asserted-by":"crossref","first-page":"1105","DOI":"10.1016\/S1044-0305(96)00072-4","volume":"7","author":"Buhrman D.","year":"1996","journal-title":"J. Am. Soc. Mass Spectrom."},{"key":"ac020361sb00008\/ac020361sb00008_1","doi-asserted-by":"crossref","first-page":"986A","DOI":"10.1021\/ac00070a716","volume":"65","author":"Kebarle P.","year":"1993","journal-title":"Anal. Chem."},{"issue":"100","key":"ac020361sb00009\/ac020361sb00009_1","first-page":"28526","volume":"66","author":"Department of Health and Human Services, Food and Drug Administration, Guidance for Industry on Bioanalytical Method Validation.","year":"2001","journal-title":"Fed. Regist."},{"issue":"12","key":"ac020361sb00010\/ac020361sb00010_1","first-page":"1557","volume":"17","author":"Shah V. P.","year":"2000","journal-title":"Pharm. Res."},{"key":"ac020361sb00011\/ac020361sb00011_1","doi-asserted-by":"crossref","first-page":"1185","DOI":"10.1002\/(SICI)1097-0231(19990630)13:12<1175::AID-RCM639>3.0.CO;2-0","volume":"13","author":"Bonfiglio R.","year":"1999","journal-title":"Rapid Commun. Mass Spectrom."},{"issue":"11","key":"ac020361sb00012\/ac020361sb00012_1","doi-asserted-by":"crossref","first-page":"950","DOI":"10.1016\/S1044-0305(00)00163-X","volume":"11","author":"King R.","year":"2000","journal-title":"J. Am. Soc. Mass Spectrom."},{"key":"ac020361sb00013\/ac020361sb00013_1","first-page":"342","volume":"907","author":"Choi B. K.","year":"2001","journal-title":"J. Chromatogr., A"},{"key":"ac020361sb00014\/ac020361sb00014_1","first-page":"377","volume":"369","author":"Choi B. K.","year":"2001","journal-title":"Fresenius' J. Anal. Chem."},{"key":"ac020361sb00015\/ac020361sb00015_1","first-page":"129","volume":"767","author":"Chavez-Eng C. M.","year":"2002","journal-title":"J. Chromatogr., B"}],"container-title":["Analytical Chemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/ac020361s","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,10,3]],"date-time":"2021-10-03T07:37:00Z","timestamp":1633246620000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/ac020361s"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2003,6,4]]},"references-count":15,"journal-issue":{"issue":"13","published-print":{"date-parts":[[2003,7,1]]}},"alternative-id":["10.1021\/ac020361s"],"URL":"https:\/\/doi.org\/10.1021\/ac020361s","relation":{},"ISSN":["0003-2700","1520-6882"],"issn-type":[{"value":"0003-2700","type":"print"},{"value":"1520-6882","type":"electronic"}],"subject":[],"published":{"date-parts":[[2003,6,4]]}}}