{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T18:41:12Z","timestamp":1791916872032,"version":"4.3.4"},"reference-count":36,"publisher":"American Chemical Society (ACS)","issue":"13","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Anal. Chem."],"published-print":{"date-parts":[[2010,7,1]]},"DOI":"10.1021\/ac100649b","type":"journal-article","created":{"date-parts":[[2010,6,8]],"date-time":"2010-06-08T13:04:19Z","timestamp":1276002259000},"page":"5669-5678","source":"Crossref","is-referenced-by-count":34,"title":["Dual-Domain Microchip-Based Process for Volume Reduction Solid Phase Extraction of Nucleic Acids from Dilute, Large Volume Biological Samples"],"prefix":"10.1021","volume":"82","author":[{"given":"Carmen R.","family":"Reedy","sequence":"first","affiliation":[{"name":"Departments of Chemistry and Mechanical Engineering, University of Virginia, Charlottesville, Virginia 22904, Department of Pathology, University of Virginia Health Science Center, Charlottesville, Virginia 22908, Lockheed Martin Corp, Rockville, Maryland 20850, and Virginia Department of Forensic Science, Richmond, Virginia 23219"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kristin A.","family":"Hagan","sequence":"additional","affiliation":[{"name":"Departments of Chemistry and Mechanical Engineering, University of Virginia, Charlottesville, Virginia 22904, Department of Pathology, University of Virginia Health Science Center, Charlottesville, Virginia 22908, Lockheed Martin Corp, Rockville, Maryland 20850, and Virginia Department of Forensic Science, Richmond, Virginia 23219"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Briony C.","family":"Strachan","sequence":"additional","affiliation":[{"name":"Departments of Chemistry and Mechanical Engineering, University of Virginia, Charlottesville, Virginia 22904, Department of Pathology, University of Virginia Health Science Center, Charlottesville, Virginia 22908, Lockheed Martin Corp, Rockville, Maryland 20850, and Virginia Department of Forensic Science, Richmond, Virginia 23219"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joshua J.","family":"Higginson","sequence":"additional","affiliation":[{"name":"Departments of Chemistry and Mechanical Engineering, University of Virginia, Charlottesville, Virginia 22904, Department of Pathology, University of Virginia Health Science Center, Charlottesville, Virginia 22908, Lockheed Martin Corp, Rockville, Maryland 20850, and Virginia Department of Forensic Science, Richmond, Virginia 23219"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joan M.","family":"Bienvenue","sequence":"additional","affiliation":[{"name":"Departments of Chemistry and Mechanical Engineering, University of Virginia, Charlottesville, Virginia 22904, Department of Pathology, University of Virginia Health Science Center, Charlottesville, Virginia 22908, Lockheed Martin Corp, Rockville, Maryland 20850, and Virginia Department of Forensic Science, Richmond, Virginia 23219"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Susan A.","family":"Greenspoon","sequence":"additional","affiliation":[{"name":"Departments of Chemistry and Mechanical Engineering, University of Virginia, Charlottesville, Virginia 22904, Department of Pathology, University of Virginia Health Science Center, Charlottesville, Virginia 22908, Lockheed Martin Corp, Rockville, Maryland 20850, and Virginia Department of Forensic Science, Richmond, Virginia 23219"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jerome P.","family":"Ferrance","sequence":"additional","affiliation":[{"name":"Departments of Chemistry and Mechanical Engineering, University of Virginia, Charlottesville, Virginia 22904, Department of Pathology, University of Virginia Health Science Center, Charlottesville, Virginia 22908, Lockheed Martin Corp, Rockville, Maryland 20850, and Virginia Department of Forensic Science, Richmond, Virginia 23219"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James P.","family":"Landers","sequence":"additional","affiliation":[{"name":"Departments of Chemistry and Mechanical Engineering, University of Virginia, Charlottesville, Virginia 22904, Department of Pathology, University of Virginia Health Science Center, Charlottesville, Virginia 22908, Lockheed Martin Corp, Rockville, Maryland 20850, and Virginia Department of Forensic Science, Richmond, Virginia 23219"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2010,6,8]]},"reference":[{"key":"ref1\/cit1","volume-title":"Forensic DNA Typing: Biology, Technology, and Genetics of STR Markers","author":"Butler J. M.","year":"2005","edition":"2"},{"key":"ref2\/cit2","doi-asserted-by":"crossref","first-page":"635","DOI":"10.1006\/jcis.1996.0421","volume":"181","author":"Melzak K. A.","year":"1996","journal-title":"J. Colloid Interface Sci."},{"key":"ref3\/cit3","volume-title":"Forensic DNA Typing: Biology & Technology behind STR Markers","author":"Butler J. M.","year":"2001","edition":"2"},{"key":"ref4\/cit4","doi-asserted-by":"crossref","first-page":"266","DOI":"10.1111\/j.1556-4029.2006.00054.x","volume":"51","author":"Bienvenue J. M.","year":"2006","journal-title":"J. Forensic Sci."},{"key":"ref5\/cit5","doi-asserted-by":"crossref","first-page":"178","DOI":"10.1016\/j.fsigen.2009.02.010","volume":"4","author":"Bienvenue J. M.","year":"2010","journal-title":"Forensic Sci. Int.: Genet."},{"key":"ref6\/cit6","doi-asserted-by":"crossref","first-page":"495","DOI":"10.1128\/jcm.28.3.495-503.1990","volume":"28","author":"Boom R.","year":"1990","journal-title":"J. Clin. Microbiol."},{"key":"ref7\/cit7","doi-asserted-by":"crossref","first-page":"1804","DOI":"10.1128\/jcm.29.9.1804-1811.1991","volume":"29","author":"Boom R.","year":"1991","journal-title":"J. Clin. Microbiol."},{"key":"ref8\/cit8","doi-asserted-by":"crossref","first-page":"1880","DOI":"10.1021\/ac0204855","volume":"75","author":"Breadmore M. C.","year":"2003","journal-title":"Anal. Chem."},{"key":"ref9\/cit9","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1016\/S0956-5663(03)00123-4","volume":"19","author":"Cady N. C.","year":"2003","journal-title":"Biosens. Bioelectron."},{"key":"ref10\/cit10","doi-asserted-by":"crossref","first-page":"7222","DOI":"10.1021\/ac060391l","volume":"78","author":"Cao W.","year":"2006","journal-title":"Anal. Chem."},{"key":"ref11\/cit11","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1115\/1.2798037","volume":"121","author":"Christel L. A.","year":"1999","journal-title":"J. Biomechanical Eng."},{"key":"ref12\/cit12","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1039\/b310849j","volume":"4","author":"Chung Y.","year":"2004","journal-title":"Lab Chip"},{"key":"ref13\/cit13","doi-asserted-by":"crossref","first-page":"19272","DOI":"10.1073\/pnas.0604663103","volume":"103","author":"Easley C. J.","year":"2006","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"ref14\/cit14","doi-asserted-by":"crossref","first-page":"8453","DOI":"10.1021\/ac8011945","volume":"80","author":"Hagan K. A.","year":"2008","journal-title":"Anal. Chem."},{"key":"ref15\/cit15","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1016\/j.jbiotec.2004.08.018","volume":"116","author":"Nakagawa T.","year":"2005","journal-title":"J. Biotechnol."},{"key":"ref16\/cit16","doi-asserted-by":"crossref","first-page":"2484","DOI":"10.1039\/b907652m","volume":"9","author":"Price C. W.","year":"2009","journal-title":"Lab Chip"},{"key":"ref17\/cit17","doi-asserted-by":"crossref","unstructured":"Reedy, C. R., Bienvenue, J. M., Coletta, L., Strachan, B. C., Bhatri, N., Greenspoon, S., and Landers, J. P.2010,4, 206\u2212212.","DOI":"10.1016\/j.fsigen.2009.09.005"},{"key":"ref18\/cit18","doi-asserted-by":"crossref","first-page":"6135","DOI":"10.1021\/ac0703698","volume":"79","author":"Wen J.","year":"2007","journal-title":"Anal. Chem."},{"key":"ref19\/cit19","doi-asserted-by":"crossref","first-page":"6472","DOI":"10.1021\/ac8014998","volume":"80","author":"Wen J.","year":"2008","journal-title":"Anal. Chem."},{"key":"ref20\/cit20","doi-asserted-by":"crossref","first-page":"8453","DOI":"10.1021\/ac8011945","volume":"80","author":"Hagan K. A.","year":"2008","journal-title":"Anal. Chem."},{"key":"ref21\/cit21","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1016\/S0379-0738(03)00197-X","volume":"135","author":"Juusola J. B., J.","year":"2003","journal-title":"Forensic Sci. Int."},{"key":"ref22\/cit22","doi-asserted-by":"crossref","first-page":"5249","DOI":"10.1021\/ac900820z","volume":"81","author":"Hagan K. A.","year":"2009","journal-title":"Anal. Chem."},{"key":"ref23\/cit23","doi-asserted-by":"crossref","first-page":"1444","DOI":"10.1021\/ac0516988","volume":"78","author":"Legendre L. A.","year":"2006","journal-title":"Anal. Chem."},{"key":"ref24\/cit24","volume-title":"Poster presentation at the 15th International Symposium on Human Identification","author":"Covert V. M.","year":"2004"},{"key":"ref25\/cit25","doi-asserted-by":"crossref","first-page":"206","DOI":"10.1016\/j.fsigen.2009.09.005","volume":"4","author":"Reedy C. R.","year":"2010","journal-title":"Forensic Sci. Int.: Genet."},{"key":"ref26\/cit26","volume-title":"AAFS Annual Meeting","author":"Wang D. Y.","year":"2007"},{"key":"ref27\/cit27","doi-asserted-by":"crossref","first-page":"647","DOI":"10.1126\/science.1066238","volume":"295","author":"Stroock A. D.","year":"2002","journal-title":"Science"},{"key":"ref28\/cit28","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1520\/JFS2002195","volume":"49","author":"Collins P. J.","year":"2004","journal-title":"J. Forensic Sci."},{"key":"ref29\/cit29","doi-asserted-by":"crossref","first-page":"1294","DOI":"10.1021\/ac0613277","volume":"79","author":"Roper M. G.","year":"2007","journal-title":"Anal. Chem."},{"key":"ref30\/cit30","unstructured":"Lovrich, N., Gaffney, M. J., Traivs, C., Pratt, P., Johson, C. L., and Lane, S. A.U.S. Department of Justice, 2004."},{"key":"ref31\/cit31","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1385\/MB:26:2:133","volume":"26","author":"Radstrom P.","year":"2004","journal-title":"Mol. Biotechnol."},{"key":"ref32\/cit32","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1016\/S0379-0738(03)00197-X","volume":"135","author":"Juusola J.","year":"2003","journal-title":"Forensic Sci. Int."},{"key":"ref33\/cit33","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1016\/j.forsciint.2005.10.009","volume":"157","author":"Nussbaumer C.","year":"2006","journal-title":"Forensic Sci. Int."},{"key":"ref34\/cit34","first-page":"2821","volume":"7","author":"Silva J. M.","year":"2001","journal-title":"Clin. Cancer Res."},{"key":"ref35\/cit35","doi-asserted-by":"crossref","first-page":"1261","DOI":"10.1373\/clinchem.2005.050666","volume":"51","author":"Masuzaki H.","year":"2005","journal-title":"Clin. Chem."},{"key":"ref36\/cit36","doi-asserted-by":"crossref","first-page":"204","DOI":"10.1196\/annals.1368.028","volume":"1075","author":"Dasi F.","year":"2006","journal-title":"Ann. N.Y. Acad. Sci."}],"container-title":["Analytical Chemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/ac100649b","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,4,3]],"date-time":"2023-04-03T18:32:58Z","timestamp":1680546778000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/ac100649b"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,6,8]]},"references-count":36,"journal-issue":{"issue":"13","published-print":{"date-parts":[[2010,7,1]]}},"alternative-id":["10.1021\/ac100649b"],"URL":"https:\/\/doi.org\/10.1021\/ac100649b","relation":{},"ISSN":["0003-2700","1520-6882"],"issn-type":[{"value":"0003-2700","type":"print"},{"value":"1520-6882","type":"electronic"}],"subject":[],"published":{"date-parts":[[2010,6,8]]}}}