{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T03:54:08Z","timestamp":1790135648314,"version":"4.0.1"},"reference-count":39,"publisher":"American Chemical Society (ACS)","issue":"18","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Anal. Chem."],"published-print":{"date-parts":[[2012,9,18]]},"DOI":"10.1021\/ac301418f","type":"journal-article","created":{"date-parts":[[2012,8,15]],"date-time":"2012-08-15T19:07:37Z","timestamp":1345057657000},"page":"7926-7932","source":"Crossref","is-referenced-by-count":65,"title":["Immuno\u2013MS Based Targeted Proteomics: Highly Specific, Sensitive, and Reproducible Human Chorionic Gonadotropin Determination for Clinical Diagnostics and Doping Analysis"],"prefix":"10.1021","volume":"84","author":[{"given":"Hanne","family":"Lund","sequence":"first","affiliation":[{"name":"Department of Pharmaceutical\rChemistry, School of Pharmacy, University of Oslo, Oslo, Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karoline","family":"L\u00f8vsletten","sequence":"additional","affiliation":[{"name":"Department of Pharmaceutical\rChemistry, School of Pharmacy, University of Oslo, Oslo, Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elisabeth","family":"Paus","sequence":"additional","affiliation":[{"name":"Central\rLaboratory, Radiumhospitalet,\rRikshospitalet, Oslo University Hospital, Oslo, Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Trine Gr\u00f8nhaug","family":"Halvorsen","sequence":"additional","affiliation":[{"name":"Department of Pharmaceutical\rChemistry, School of Pharmacy, University of Oslo, Oslo, Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L\u00e9on","family":"Reubsaet","sequence":"additional","affiliation":[{"name":"Department of Pharmaceutical\rChemistry, School of Pharmacy, University of Oslo, Oslo, Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2012,8,30]]},"reference":[{"issue":"1","key":"ref1\/cit1","first-page":"6","volume":"3","author":"Palmblad M.","year":"2009","journal-title":"Proteomics: Clin. Appl."},{"issue":"11","key":"ref2\/cit2a","doi-asserted-by":"crossref","first-page":"1941","DOI":"10.1002\/cbic.200500151","volume":"6","author":"Want E. J.","year":"2005","journal-title":"ChemBioChem"},{"issue":"4","key":"ref2\/cit2b","doi-asserted-by":"crossref","first-page":"296","DOI":"10.1016\/j.clinbiochem.2005.01.017","volume":"38","author":"Chace D. H.","year":"2005","journal-title":"Clin. Biochem."},{"issue":"7","key":"ref3\/cit3","doi-asserted-by":"crossref","first-page":"633","DOI":"10.1038\/nbt.1546","volume":"27","author":"Addona T. A.","year":"2009","journal-title":"Nat. Biotechnol."},{"issue":"18","key":"ref4\/cit4a","doi-asserted-by":"crossref","first-page":"2211","DOI":"10.1001\/jama.286.18.2211","volume":"286","author":"Liotta L. A.","year":"2001","journal-title":"JAMA, J. Am. Med. Assoc."},{"issue":"7","key":"ref4\/cit4b","doi-asserted-by":"crossref","first-page":"622","DOI":"10.1038\/nbt0709-622","volume":"27","author":"McIntosh M.","year":"2009","journal-title":"Nat. Biotechnol."},{"issue":"6","key":"ref4\/cit4c","doi-asserted-by":"crossref","first-page":"631","DOI":"10.1586\/14789450.3.6.631","volume":"3","author":"Nedelkov D.","year":"2006","journal-title":"Expert Rev. Proteomics"},{"issue":"9","key":"ref4\/cit4d","doi-asserted-by":"crossref","first-page":"683","DOI":"10.1038\/nrd891","volume":"1","author":"Petricoin E. F.","year":"2002","journal-title":"Nat. Rev. Drug Discovry"},{"issue":"9306","key":"ref4\/cit4e","doi-asserted-by":"crossref","first-page":"572","DOI":"10.1016\/S0140-6736(02)07746-2","volume":"359","author":"Petricoin E. F.","year":"2002","journal-title":"The Lancet"},{"issue":"1","key":"ref5\/cit5","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1038\/nmeth.f.329","volume":"8","author":"Doerr A.","year":"2011","journal-title":"Nat. Methods"},{"issue":"11","key":"ref6\/cit6","doi-asserted-by":"crossref","first-page":"5241","DOI":"10.1021\/pr900580n","volume":"8","author":"Lund H.","year":"2009","journal-title":"J. Proteome Res."},{"issue":"3","key":"ref7\/cit7a","doi-asserted-by":"crossref","first-page":"644","DOI":"10.1021\/pr049963d","volume":"3","author":"Barnidge D. R.","year":"2004","journal-title":"J. Proteome Res."},{"issue":"12","key":"ref7\/cit7b","doi-asserted-by":"crossref","first-page":"2212","DOI":"10.1074\/mcp.M700354-MCP200","volume":"6","author":"Keshishian H.","year":"2007","journal-title":"Mol. Cell. Proteomics"},{"issue":"17","key":"ref8\/cit8","doi-asserted-by":"crossref","first-page":"2937","DOI":"10.1002\/jssc.200900233","volume":"32","author":"Winther B.","year":"2009","journal-title":"J. Sep. Sci."},{"issue":"3","key":"ref9\/cit9a","doi-asserted-by":"crossref","first-page":"497","DOI":"10.1677\/joe.0.1720497","volume":"172","author":"Kovalevskaya G.","year":"2002","journal-title":"J. Endocrinol."},{"issue":"12","key":"ref9\/cit9b","doi-asserted-by":"crossref","first-page":"2131","DOI":"10.1093\/clinchem\/47.12.2131","volume":"47","author":"Butler S. A.","year":"2001","journal-title":"Clin. Chem."},{"issue":"12","key":"ref9\/cit9c","doi-asserted-by":"crossref","first-page":"2233","DOI":"10.1093\/clinchem\/43.12.2233","volume":"43","author":"Cole L. A.","year":"1997","journal-title":"Clin. Chem."},{"issue":"8","key":"ref9\/cit9d","doi-asserted-by":"crossref","first-page":"647","DOI":"10.1016\/S0009-9120(03)00108-5","volume":"36","author":"Cole L. A.","year":"2003","journal-title":"Clin. Biochem."},{"issue":"6","key":"ref10\/cit10","doi-asserted-by":"crossref","first-page":"769","DOI":"10.1093\/humupd\/dml029","volume":"12","author":"Stenman U.-H.","year":"2006","journal-title":"Hum. Reprod. Update"},{"issue":"7","key":"ref11\/cit11","doi-asserted-by":"crossref","first-page":"549","DOI":"10.1016\/j.clinbiochem.2004.05.008","volume":"37","author":"Stenman U.-H.","year":"2004","journal-title":"Clin. Biochem."},{"issue":"2","key":"ref12\/cit12a","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1016\/j.ygyno.2005.12.045","volume":"102","author":"Cole L. A.","year":"2006","journal-title":"Gynecol. Oncol."},{"issue":"2","key":"ref12\/cit12b","doi-asserted-by":"crossref","first-page":"160","DOI":"10.1016\/j.ygyno.2005.12.046","volume":"102","author":"Cole L. A.","year":"2006","journal-title":"Gynecol. Oncol."},{"issue":"3","key":"ref12\/cit12c","doi-asserted-by":"crossref","first-page":"663","DOI":"10.1016\/j.ygyno.2008.09.030","volume":"112","author":"Muller C. Y.","year":"2009","journal-title":"Gynecol. Oncol."},{"issue":"11","key":"ref13\/cit13a","doi-asserted-by":"crossref","first-page":"1840","DOI":"10.1373\/clinchem.2008.108548","volume":"54","author":"Lempiainen A.","year":"2008","journal-title":"Clin. Chem."},{"issue":"8856","key":"ref13\/cit13b","doi-asserted-by":"crossref","first-page":"1354","DOI":"10.1016\/0140-6736(93)90872-E","volume":"341","author":"Marcillac I.","year":"1993","journal-title":"Lancet"},{"issue":"14","key":"ref13\/cit13c","first-page":"3901","volume":"52","author":"Marcillac I.","year":"1992","journal-title":"Cancer Res."},{"issue":"2","key":"ref13\/cit13d","doi-asserted-by":"crossref","first-page":"234","DOI":"10.1093\/clinchem\/36.2.234","volume":"36","author":"Saller B.","year":"1990","journal-title":"Clin. Chem."},{"issue":"4","key":"ref14\/cit14","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1053\/j.semperi.2005.05.006","volume":"29","author":"Wald N. J.","year":"2005","journal-title":"Semin. Perinatol."},{"issue":"3","key":"ref15\/cit15","doi-asserted-by":"crossref","first-page":"569","DOI":"10.1038\/bjp.2008.102","volume":"154","author":"Stenman U. H.","year":"2008","journal-title":"Br. J. Pharmacol."},{"key":"ref16\/cit16","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1586\/14737159.9.1.51","volume":"9","author":"Cole L. A.","year":"2009","journal-title":"Expert Rev. Mol. Diagn."},{"issue":"1","key":"ref17\/cit17","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1186\/1477-7827-7-8","volume":"7","author":"Cole L.","year":"2009","journal-title":"Reprod. Biol. Endocrinol."},{"issue":"6480","key":"ref18\/cit18a","doi-asserted-by":"crossref","first-page":"455","DOI":"10.1038\/369455a0","volume":"369","author":"Lapthorn A. J.","year":"1994","journal-title":"Nature"},{"issue":"1","key":"ref18\/cit18b","doi-asserted-by":"crossref","first-page":"465","DOI":"10.1146\/annurev.bi.50.070181.002341","volume":"50","author":"Pierce J. G.","year":"1981","journal-title":"Annu. Rev. Biochem."},{"issue":"1","key":"ref19\/cit19","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1159\/000048686","volume":"23","author":"Berger P.","year":"2002","journal-title":"Tumor Biol."},{"issue":"1","key":"ref20\/cit20","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1016\/j.cca.2011.09.037","volume":"413","author":"Cole L. A.","year":"2012","journal-title":"Clin. Chim. Acta"},{"issue":"2","key":"ref21\/cit21","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1016\/S1570-0232(03)00264-2","volume":"792","author":"Gam L.-H.","year":"2003","journal-title":"J. Chromatogr., B"},{"issue":"10","key":"ref22\/cit22","doi-asserted-by":"crossref","first-page":"2034","DOI":"10.1093\/clinchem\/35.10.2034","volume":"35","author":"Paus E.","year":"1989","journal-title":"Clin. Chem."},{"key":"ref23\/cit23","unstructured":"(EMEA). E. M. A. Guideline on Validation of Bioanalytical Methods, 2009.http:\/\/www.ema.europa.eu\/docs\/en_GB\/document_library\/Scientific_guideline\/2011\/08\/WC500109686.pdf(accessed April 20, 2012)."},{"issue":"1","key":"ref24\/cit24","doi-asserted-by":"crossref","first-page":"232","DOI":"10.1016\/j.cca.2011.09.038","volume":"413","author":"Lempi\u00e4inen A.","year":"2012","journal-title":"Clin. Chim. Acta"}],"container-title":["Analytical Chemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/ac301418f","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,4,2]],"date-time":"2023-04-02T16:17:34Z","timestamp":1680452254000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/ac301418f"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,8,30]]},"references-count":39,"journal-issue":{"issue":"18","published-print":{"date-parts":[[2012,9,18]]}},"alternative-id":["10.1021\/ac301418f"],"URL":"https:\/\/doi.org\/10.1021\/ac301418f","relation":{},"ISSN":["0003-2700","1520-6882"],"issn-type":[{"value":"0003-2700","type":"print"},{"value":"1520-6882","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,8,30]]}}}