{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,4]],"date-time":"2026-10-04T19:25:35Z","timestamp":1791141935070,"version":"4.1.0"},"reference-count":40,"publisher":"American Chemical Society (ACS)","issue":"8","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Anal. Chem."],"published-print":{"date-parts":[[2008,4,15]]},"DOI":"10.1021\/ac702350g","type":"journal-article","created":{"date-parts":[[2008,3,4]],"date-time":"2008-03-04T10:01:10Z","timestamp":1204624870000},"page":"2780-2788","source":"Crossref","is-referenced-by-count":142,"title":["Imaging MALDI Mass Spectrometry Using an Oscillating Capillary Nebulizer Matrix Coating System and Its Application to Analysis of Lipids in Brain from a Mouse Model of Tay\u2212Sachs\/Sandhoff Disease"],"prefix":"10.1021","volume":"80","author":[{"given":"Yanfeng","family":"Chen","sequence":"first","affiliation":[{"name":"Schools of Chemistry and Biochemistry and Biology, The Parker H. Petit Institute for Bioengineering and Bioscience, 315 Ferst Drive, Georgia Institute of Technology, Atlanta, Georgia 30332-0363, and Department of Medicine, University of Cambridge, Level 5, BOX 157, Addenbrooke's Hospital, Hills Road, Cambridge CB2QQ, United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeremy","family":"Allegood","sequence":"additional","affiliation":[{"name":"Schools of Chemistry and Biochemistry and Biology, The Parker H. Petit Institute for Bioengineering and Bioscience, 315 Ferst Drive, Georgia Institute of Technology, Atlanta, Georgia 30332-0363, and Department of Medicine, University of Cambridge, Level 5, BOX 157, Addenbrooke's Hospital, Hills Road, Cambridge CB2QQ, United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ying","family":"Liu","sequence":"additional","affiliation":[{"name":"Schools of Chemistry and Biochemistry and Biology, The Parker H. Petit Institute for Bioengineering and Bioscience, 315 Ferst Drive, Georgia Institute of Technology, Atlanta, Georgia 30332-0363, and Department of Medicine, University of Cambridge, Level 5, BOX 157, Addenbrooke's Hospital, Hills Road, Cambridge CB2QQ, United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elaine","family":"Wang","sequence":"additional","affiliation":[{"name":"Schools of Chemistry and Biochemistry and Biology, The Parker H. Petit Institute for Bioengineering and Bioscience, 315 Ferst Drive, Georgia Institute of Technology, Atlanta, Georgia 30332-0363, and Department of Medicine, University of Cambridge, Level 5, BOX 157, Addenbrooke's Hospital, Hills Road, Cambridge CB2QQ, United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bego\u00f1a","family":"Cach\u00f3n-Gonz\u00e1lez","sequence":"additional","affiliation":[{"name":"Schools of Chemistry and Biochemistry and Biology, The Parker H. Petit Institute for Bioengineering and Bioscience, 315 Ferst Drive, Georgia Institute of Technology, Atlanta, Georgia 30332-0363, and Department of Medicine, University of Cambridge, Level 5, BOX 157, Addenbrooke's Hospital, Hills Road, Cambridge CB2QQ, United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Timothy M.","family":"Cox","sequence":"additional","affiliation":[{"name":"Schools of Chemistry and Biochemistry and Biology, The Parker H. Petit Institute for Bioengineering and Bioscience, 315 Ferst Drive, Georgia Institute of Technology, Atlanta, Georgia 30332-0363, and Department of Medicine, University of Cambridge, Level 5, BOX 157, Addenbrooke's Hospital, Hills Road, Cambridge CB2QQ, United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alfred H.","family":"Merrill,","sequence":"additional","affiliation":[{"name":"Schools of Chemistry and Biochemistry and Biology, The Parker H. Petit Institute for Bioengineering and Bioscience, 315 Ferst Drive, Georgia Institute of Technology, Atlanta, Georgia 30332-0363, and Department of Medicine, University of Cambridge, Level 5, BOX 157, Addenbrooke's Hospital, Hills Road, Cambridge CB2QQ, United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M. Cameron","family":"Sullards","sequence":"additional","affiliation":[{"name":"Schools of Chemistry and Biochemistry and Biology, The Parker H. Petit Institute for Bioengineering and Bioscience, 315 Ferst Drive, Georgia Institute of Technology, Atlanta, Georgia 30332-0363, and Department of Medicine, University of Cambridge, Level 5, BOX 157, Addenbrooke's Hospital, Hills Road, Cambridge CB2QQ, United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2008,3,4]]},"reference":[{"key":"ac702350gb00001\/ac702350gb00001_1","doi-asserted-by":"crossref","first-page":"4751","DOI":"10.1021\/ac970888i","volume":"69","author":"Caprioli R. M.","year":"1997","journal-title":"Anal. Chem."},{"key":"ac702350gb00002\/ac702350gb00002_1","doi-asserted-by":"crossref","first-page":"86A","DOI":"10.1021\/ac0415197","volume":"76","author":"Chaurand P.","year":"2004","journal-title":"Anal. Chem."},{"key":"ac702350gb00003\/ac702350gb00003_1","doi-asserted-by":"crossref","first-page":"5374","DOI":"10.1021\/ac034498+","volume":"75","author":"Rubakhin S. S.","year":"2003","journal-title":"Anal. Chem."},{"key":"ac702350gb00004\/ac702350gb00004_1","doi-asserted-by":"crossref","first-page":"606","DOI":"10.1002\/mas.20124","volume":"26","author":"McDonnell L. A.","year":"2007","journal-title":"Mass Spectrom. Rev."},{"key":"ac702350gb00005\/ac702350gb00005_1","doi-asserted-by":"crossref","first-page":"699","DOI":"10.1002\/jms.505","volume":"38","author":"Schwartz S. A.","year":"2003","journal-title":"J. Mass Spectrom."},{"key":"ac702350gb00006\/ac702350gb00006_1","doi-asserted-by":"crossref","first-page":"827","DOI":"10.1021\/ac051534r","volume":"78","author":"Aerni H. R.","year":"2006","journal-title":"Anal. Chem."},{"key":"ac702350gb00007\/ac702350gb00007_1","doi-asserted-by":"crossref","first-page":"6862","DOI":"10.1021\/ac070958d","volume":"79","author":"Baluya D. L.","year":"2007","journal-title":"Anal. Chem."},{"key":"ac702350gb00008\/ac702350gb00008_1","doi-asserted-by":"crossref","first-page":"1785","DOI":"10.1002\/(SICI)1097-0231(19971030)11:16<1785::AID-RCM78>3.0.CO;2-Q","volume":"11","author":"Hensel R. R.","year":"1997","journal-title":"Rapid Commun. Mass Spectrom."},{"key":"ac702350gb00009\/ac702350gb00009_1","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1002\/(SICI)1097-0231(19970131)11:2<209::AID-RCM734>3.0.CO;2-E","volume":"11","author":"Axelsson J.","year":"1997","journal-title":"J. Rapid Commun. Mass Spectrom."},{"key":"ac702350gb00010\/ac702350gb00010_1","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1016\/j.chroma.2007.01.045","volume":"1153","author":"Canas B.","year":"2007","journal-title":"J. Chromatogr., A"},{"key":"ac702350gb00011\/ac702350gb00011_1","doi-asserted-by":"crossref","first-page":"1654","DOI":"10.1016\/j.jasms.2005.06.006","volume":"16","author":"Jurchen J. C.","year":"2005","journal-title":"J. Am. Soc. Mass Spectrom."},{"key":"ac702350gb00012\/ac702350gb00012_1","doi-asserted-by":"crossref","first-page":"1399","DOI":"10.1021\/ac001440b","volume":"73","author":"Stockle R.","year":"2001","journal-title":"Anal. Chem."},{"key":"ac702350gb00013\/ac702350gb00013_1","doi-asserted-by":"crossref","first-page":"735","DOI":"10.1016\/S1044-0305(02)00376-8","volume":"13","author":"Spengler B.","year":"2002","journal-title":"J. Am. Soc. Mass Spectrom."},{"key":"ac702350gb00014\/ac702350gb00014_1","doi-asserted-by":"crossref","first-page":"476","DOI":"10.1002\/jms.1180","volume":"42","author":"Chaurand P.","year":"2007","journal-title":"J. Mass Spectrom."},{"key":"ac702350gb00015\/ac702350gb00015_1","doi-asserted-by":"crossref","first-page":"2373","DOI":"10.1021\/ac062251h","volume":"79","author":"Cha S.","year":"2007","journal-title":"Anal. Chem."},{"key":"ac702350gb00016\/ac702350gb00016_1","doi-asserted-by":"crossref","first-page":"166","DOI":"10.1016\/j.ijms.2006.09.019","volume":"260","author":"Garrett T. J.","year":"2007","journal-title":"Int. J. Mass Spectrom."},{"key":"ac702350gb00017\/ac702350gb00017_1","doi-asserted-by":"crossref","first-page":"735","DOI":"10.1021\/ac048329g","volume":"77","author":"Altelaar A. F. M.","year":"2005","journal-title":"Anal. Chem."},{"key":"ac702350gb00018\/ac702350gb00018_1","doi-asserted-by":"crossref","first-page":"7094","DOI":"10.1002\/anie.200502362","volume":"44","author":"Wiseman J. M.","year":"2005","journal-title":"Angew. Chem., Int. Ed."},{"key":"ac702350gb00019\/ac702350gb00019_1","doi-asserted-by":"crossref","first-page":"1137","DOI":"10.1039\/JA9961101137","volume":"11","author":"Wang L.","year":"1996","journal-title":"J. Anal. At. Spectrom."},{"key":"ac702350gb00020\/ac702350gb00020_1","doi-asserted-by":"crossref","first-page":"223","DOI":"10.3109\/10837459609022590","volume":"1","author":"Reyderman L.","year":"1996","journal-title":"Pharm. Dev. Technol."},{"key":"ac702350gb00021\/ac702350gb00021_1","doi-asserted-by":"crossref","first-page":"1105","DOI":"10.1016\/S1044-0305(99)00084-7","volume":"10","author":"Perez J.","year":"1999","journal-title":"J. Am. Soc. Mass Spectrom."},{"key":"ac702350gb00022\/ac702350gb00022_1","doi-asserted-by":"crossref","first-page":"1008","DOI":"10.1002\/(SICI)1097-0231(20000615)14:11<1008::AID-RCM979>3.0.CO;2-T","volume":"14","author":"Lake D. A.","year":"2000","journal-title":"Rapid Commun. Mass Spectrom."},{"key":"ac702350gb00023\/ac702350gb00023_1","doi-asserted-by":"crossref","first-page":"3121","DOI":"10.1002\/pmic.200300843","volume":"4","author":"Fung K. Y. C.","year":"2004","journal-title":"Proteomics"},{"key":"ac702350gb00024\/ac702350gb00024_1","doi-asserted-by":"crossref","first-page":"3008","DOI":"10.1021\/ac048391d","volume":"77","author":"Basile F.","year":"2005","journal-title":"Anal. Chem."},{"key":"ac702350gb00025\/ac702350gb00025_1","doi-asserted-by":"crossref","first-page":"770","DOI":"10.1366\/0003702981944210","volume":"52","author":"Kirlew P. W.","year":"1998","journal-title":"Appl. Spectrosc."},{"key":"ac702350gb00026\/ac702350gb00026_1","doi-asserted-by":"crossref","first-page":"10373","DOI":"10.1073\/pnas.0603765103","volume":"103","author":"Cachon-Gonzalez M. B.","year":"2006","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"ac702350gb00027\/ac702350gb00027_1","doi-asserted-by":"crossref","first-page":"64","DOI":"10.1016\/S0076-6879(00)12900-3","volume-title":"Sphingolipid Metabolism and Cell Signaling, Part B","volume":"312","author":"van Echten-Deckert G.","year":"2000"},{"key":"ac702350gb00028\/ac702350gb00028_1","doi-asserted-by":"crossref","first-page":"2745","DOI":"10.1021\/ac062129i","volume":"79","author":"Ng K. M.","year":"2007","journal-title":"Anal. Chem."},{"key":"ac702350gb00029\/ac702350gb00029_1","doi-asserted-by":"crossref","first-page":"490","DOI":"10.1016\/j.jasms.2005.12.007","volume":"17","author":"Zhang X.","year":"2006","journal-title":"J. Am. Soc. Mass Spectrom."},{"key":"ac702350gb00030\/ac702350gb00030_1","doi-asserted-by":"crossref","first-page":"94","DOI":"10.1111\/j.1399-3011.2005.00277.x","volume":"66","author":"Jagannadham M. V.","year":"2005","journal-title":"J. Pept. Res."},{"key":"ac702350gb00031\/ac702350gb00031_1","doi-asserted-by":"crossref","first-page":"254","DOI":"10.1002\/jms.1177","volume":"42","author":"Groseclose M. R.","year":"2007","journal-title":"J. Mass Spectrom."},{"key":"ac702350gb00032\/ac702350gb00032_1","doi-asserted-by":"crossref","first-page":"466","DOI":"10.1002\/pmic.200300567","volume":"4","author":"Padliya N. D.","year":"2004","journal-title":"Proteomics"},{"key":"ac702350gb00033\/ac702350gb00033_1","volume-title":"Anal. Technol. Biomed. Life Sci","author":"Fujiwaki T.","year":"2002"},{"key":"ac702350gb00034\/ac702350gb00034_1","doi-asserted-by":"crossref","first-page":"1646","DOI":"10.1016\/j.jasms.2007.06.010","volume":"18","author":"Hankin J. A.","year":"2007","journal-title":"J. Am. Soc. Mass Spectrom."},{"key":"ac702350gb00035\/ac702350gb00035_1","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1194\/jlr.M300331-JLR200","volume":"45","author":"Colsch B.","year":"2004","journal-title":"J. Lipid Res."},{"key":"ac702350gb00036\/ac702350gb00036_1","doi-asserted-by":"crossref","first-page":"3979","DOI":"10.1073\/pnas.75.8.3979","volume":"75","author":"Conzelmann E.","year":"1978","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"ac702350gb00037\/ac702350gb00037_1","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1016\/j.ymeth.2005.01.009","volume":"36","author":"Merrill A. H.","year":"2005","journal-title":"Methods"},{"key":"ac702350gb00038\/ac702350gb00038_1","volume-title":"Basic Neurochemistry","author":"Benjamins J. A.","year":"2006","edition":"7"},{"key":"ac702350gb00039\/ac702350gb00039_1","doi-asserted-by":"crossref","first-page":"2463","DOI":"10.1021\/ac061768q","volume":"79","author":"Dreisewerd K.","year":"2007","journal-title":"Anal. Chem."},{"key":"ac702350gb00040\/ac702350gb00040_1","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1016\/j.jasms.2006.08.015","volume":"18","author":"Jackson S. N.","year":"2007","journal-title":"J. Am. Soc. Mass Spectrom."}],"container-title":["Analytical Chemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/ac702350g","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,3,16]],"date-time":"2023-03-16T07:58:25Z","timestamp":1678953505000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/ac702350g"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,3,4]]},"references-count":40,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2008,4,15]]}},"alternative-id":["10.1021\/ac702350g"],"URL":"https:\/\/doi.org\/10.1021\/ac702350g","relation":{},"ISSN":["0003-2700","1520-6882"],"issn-type":[{"value":"0003-2700","type":"print"},{"value":"1520-6882","type":"electronic"}],"subject":[],"published":{"date-parts":[[2008,3,4]]}}}