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Chem."},{"key":"ref20\/cit20","doi-asserted-by":"crossref","first-page":"5646","DOI":"10.1021\/ac0346510","volume":"75","author":"McClain M. A.","year":"2003","journal-title":"Anal. Chem."},{"key":"ref21\/cit21","doi-asserted-by":"crossref","first-page":"12809","DOI":"10.1073\/pnas.0405299101","volume":"101","author":"Wu H.","year":"2004","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"ref22\/cit22","doi-asserted-by":"crossref","first-page":"1798","DOI":"10.1021\/ac015640e","volume":"74","author":"Schilling E. A.","year":"2002","journal-title":"Anal. Chem."},{"key":"ref23\/cit23","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1039\/b310552k","volume":"4","author":"Gao J.","year":"2004","journal-title":"Lab Chip"},{"key":"ref24\/cit24","doi-asserted-by":"crossref","first-page":"158","DOI":"10.1021\/ac970642d","volume":"70","author":"Waters L. C.","year":"1998","journal-title":"Anal. 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