{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,24]],"date-time":"2026-10-24T01:15:54Z","timestamp":1792804554388,"version":"4.5.0"},"reference-count":27,"publisher":"American Chemical Society (ACS)","issue":"14","license":[{"start":{"date-parts":[[2020,7,2]],"date-time":"2020-07-02T00:00:00Z","timestamp":1593648000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-001"},{"start":{"date-parts":[[2020,7,2]],"date-time":"2020-07-02T00:00:00Z","timestamp":1593648000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-009"},{"start":{"date-parts":[[2020,7,2]],"date-time":"2020-07-02T00:00:00Z","timestamp":1593648000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"}],"funder":[{"DOI":"10.13039\/100007219","name":"Natural Science Foundation of Shanghai","doi-asserted-by":"publisher","award":["12ZR1401700"],"award-info":[{"award-number":["12ZR1401700"]}],"id":[{"id":"10.13039\/100007219","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100007219","name":"Natural Science Foundation of Shanghai","doi-asserted-by":"publisher","award":["17JC1400100"],"award-info":[{"award-number":["17JC1400100"]}],"id":[{"id":"10.13039\/100007219","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100007219","name":"Natural Science Foundation of Shanghai","doi-asserted-by":"publisher","award":["19441903900"],"award-info":[{"award-number":["19441903900"]}],"id":[{"id":"10.13039\/100007219","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002855","name":"Ministry of Science and Technology of the People's Republic of China","doi-asserted-by":"publisher","award":["2017YFA0205100"],"award-info":[{"award-number":["2017YFA0205100"]}],"id":[{"id":"10.13039\/501100002855","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["21974028"],"award-info":[{"award-number":["21974028"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2020,7,21]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>The outbreak of SARS-CoV-2 is posing serious global public health problems. Facing the emergence of this pandemic, we established a portable microfluidic immunoassay system for easy-to-use, sensitive, rapid (&amp;lt;15 min), multiple, and on-site detection of IgG\/IgM\/Antigen of SARS-CoV-2 simultaneously. This integrated method was successfully applied for detecting SARS-CoV-2 IgM and IgG antibodies in clinical human serum as well as SARS-CoV-2 antigen in pharyngeal swabs from 26 patients with COVID-19 infection and 28 uninfected people. The assay demonstrated high sensitivity and specificity, which is promising for the diagnosis and monitoring as well as control of SARS-CoV-2 worldwide.<\/jats:p>","DOI":"10.1021\/acs.analchem.0c01635","type":"journal-article","created":{"date-parts":[[2020,7,2]],"date-time":"2020-07-02T18:03:47Z","timestamp":1593713027000},"page":"9454-9458","source":"Crossref","is-referenced-by-count":195,"title":["Microfluidic Immunoassays for Sensitive and Simultaneous\nDetection of IgG\/IgM\/Antigen of SARS-CoV\u20112 within 15 min"],"prefix":"10.1021","volume":"92","author":[{"given":"Qiuyuan","family":"Lin","sequence":"first","affiliation":[{"name":"Shanghai Suxin Biotechnology Co. Ltd. , ,","place":["Shanghai, P. R. China, 201318"]},{"name":"NingBo iGeneTec Technology Co. Ltd. , ,","place":["Ningbo, P. R. China, 315000"]},{"name":"Fudan University , , ,","place":["Shanghai, P. R. China, 200433"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Donghua","family":"Wen","sequence":"additional","affiliation":[{"name":"Tongji University School of Medicine , , ,","place":["Shanghai, P. R. China, 200123"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jing","family":"Wu","sequence":"additional","affiliation":[{"name":"Shanghai Suxin Biotechnology Co. Ltd. , ,","place":["Shanghai, P. R. China, 201318"]},{"name":"NingBo iGeneTec Technology Co. Ltd. , ,","place":["Ningbo, P. R. China, 315000"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Liling","family":"Liu","sequence":"additional","affiliation":[{"name":"Shanghai Suxin Biotechnology Co. Ltd. , ,","place":["Shanghai, P. R. China, 201318"]},{"name":"NingBo iGeneTec Technology Co. Ltd. , ,","place":["Ningbo, P. R. China, 315000"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wenjuan","family":"Wu","sequence":"additional","affiliation":[{"name":"Tongji University School of Medicine , , ,","place":["Shanghai, P. R. China, 200123"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3266-7868","authenticated-orcid":true,"given":"Xueen","family":"Fang","sequence":"additional","affiliation":[{"name":"Shanghai Suxin Biotechnology Co. Ltd. , ,","place":["Shanghai, P. R. China, 201318"]},{"name":"NingBo iGeneTec Technology Co. Ltd. , ,","place":["Ningbo, P. R. China, 315000"]},{"name":"Fudan University , , ,","place":["Shanghai, P. R. China, 200433"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jilie","family":"Kong","sequence":"additional","affiliation":[{"name":"Shanghai Suxin Biotechnology Co. Ltd. , ,","place":["Shanghai, P. R. China, 201318"]},{"name":"NingBo iGeneTec Technology Co. Ltd. , ,","place":["Ningbo, P. R. China, 315000"]},{"name":"Fudan University , , ,","place":["Shanghai, P. R. China, 200433"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2020,7,2]]},"reference":[{"key":"2026081803310609800_cit1","doi-asserted-by":"publisher","first-page":"470","DOI":"10.1016\/S0140-6736(20)30185-9","article-title":"A novel coronavirus\noutbreak of global health concern","volume":"395","author":"Wang","year":"2020","journal-title":"Lancet"},{"key":"2026081803310609800_cit2","doi-asserted-by":"publisher","first-page":"264","DOI":"10.1016\/j.ijid.2020.01.009","article-title":"The continuing 2019-nCoV epidemic\nthreat of novel coronaviruses to global health - The latest 2019 novel\ncoronavirus outbreak in Wuhan, China","volume":"91","author":"Hui","year":"2020","journal-title":"Int. J.\nInfect. 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Infect. Dis."},{"key":"2026081803310609800_cit18","doi-asserted-by":"publisher","DOI":"10.1002\/jmv.25727","article-title":"Development\nand Clinical Application of A Rapid IgM-IgG Combined Antibody Test\nfor SARS-CoV-2 Infection Diagnosis","author":"Li","year":"2020","journal-title":"J. Med.\nVirol."},{"key":"2026081803310609800_cit19","doi-asserted-by":"publisher","DOI":"10.1016\/j.cmi.2020.05.023","article-title":"Diagnostic performance of 7 rapid\nIgG\/IgM antibody tests and the Euroimmun IgA\/IgG ELISA in COVID-19\npatients","author":"Van\nElslande","year":"2020","journal-title":"Clin. Microbiol. Infect."},{"key":"2026081803310609800_cit20","doi-asserted-by":"publisher","DOI":"10.1016\/j.cmi.2020.05.028","article-title":"Comparison of\ndiagnostic accuracies of rapid serological tests and ELISA to molecular\ndiagnostics in patients with suspected coronavirus disease 2019 presenting\nto the hospital","author":"Ong","year":"2020","journal-title":"Clin. Microbiol. 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