{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,7]],"date-time":"2026-11-07T07:14:18Z","timestamp":1794035658661,"version":"4.8.0"},"reference-count":46,"publisher":"American Chemical Society (ACS)","issue":"2","license":[{"start":{"date-parts":[[2021,12,28]],"date-time":"2021-12-28T00:00:00Z","timestamp":1640649600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2021,12,28]],"date-time":"2021-12-28T00:00:00Z","timestamp":1640649600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2021,12,28]],"date-time":"2021-12-28T00:00:00Z","timestamp":1640649600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-045"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["22077112"],"award-info":[{"award-number":["22077112"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81603104"],"award-info":[{"award-number":["81603104"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81673417"],"award-info":[{"award-number":["81673417"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"name":"National Science and Technology Major Project ???Key New Drug Creation and Manufacturing Program???","award":["2018ZX09711002-010-004"],"award-info":[{"award-number":["2018ZX09711002-010-004"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Anal. Chem."],"published-print":{"date-parts":[[2022,1,18]]},"DOI":"10.1021\/acs.analchem.1c04520","type":"journal-article","created":{"date-parts":[[2021,12,28]],"date-time":"2021-12-28T19:56:22Z","timestamp":1640721382000},"page":"1308-1317","source":"Crossref","is-referenced-by-count":38,"title":["In Situ Imaging of Formaldehyde in Live Mice with High Spatiotemporal Resolution Reveals Aldehyde Dehydrogenase-2 as a Potential Target for Alzheimer\u2019s Disease Treatment"],"prefix":"10.1021","volume":"94","author":[{"given":"Rongrong","family":"Tao","sequence":"first","affiliation":[{"name":"Medical College of Acupuncture-Moxibustion and Rehabilitation, Guangzhou University of Chinese Medicine, Guangzhou 510006 Guangdong, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Meihua","family":"Liao","sequence":"additional","affiliation":[{"name":"Medical College of Acupuncture-Moxibustion and Rehabilitation, Guangzhou University of Chinese Medicine, Guangzhou 510006 Guangdong, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuxiang","family":"Wang","sequence":"additional","affiliation":[{"name":"College of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310058 Zhejiang, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Huan","family":"Wang","sequence":"additional","affiliation":[{"name":"College of Life Science and Technology, Dalian University, Dalian 116622 Liaoning, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuhang","family":"Tan","sequence":"additional","affiliation":[{"name":"Medical College of Acupuncture-Moxibustion and Rehabilitation, Guangzhou University of Chinese Medicine, Guangzhou 510006 Guangdong, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Siyao","family":"Qin","sequence":"additional","affiliation":[{"name":"Department of Chemistry, Zhejiang Sci-Tech University, Hangzhou 310018 Zhejiang, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wenjing","family":"Wei","sequence":"additional","affiliation":[{"name":"Medical College of Acupuncture-Moxibustion and Rehabilitation, Guangzhou University of Chinese Medicine, Guangzhou 510006 Guangdong, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chunzhi","family":"Tang","sequence":"additional","affiliation":[{"name":"Medical College of Acupuncture-Moxibustion and Rehabilitation, Guangzhou University of Chinese Medicine, Guangzhou 510006 Guangdong, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xingguang","family":"Liang","sequence":"additional","affiliation":[{"name":"College of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310058 Zhejiang, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yifeng","family":"Han","sequence":"additional","affiliation":[{"name":"Department of Chemistry, Zhejiang Sci-Tech University, Hangzhou 310018 Zhejiang, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5154-2115","authenticated-orcid":true,"given":"Xin","family":"Li","sequence":"additional","affiliation":[{"name":"College of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310058 Zhejiang, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2021,12,28]]},"reference":[{"key":"ref1\/cit1","doi-asserted-by":"publisher","DOI":"10.1038\/s41586-018-0622-0"},{"key":"ref2\/cit2","doi-asserted-by":"publisher","DOI":"10.1038\/s41590-020-0666-9"},{"key":"ref3\/cit3","doi-asserted-by":"publisher","DOI":"10.1016\/j.cmet.2018.02.003"},{"key":"ref4\/cit4","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2015.08.012"},{"key":"ref5\/cit5","doi-asserted-by":"publisher","DOI":"10.1016\/j.cbpa.2017.04.010"},{"key":"ref6\/cit6","doi-asserted-by":"publisher","DOI":"10.1016\/j.cotox.2018.07.001"},{"key":"ref7\/cit7","doi-asserted-by":"publisher","DOI":"10.2903\/j.efsa.2014.3550"},{"key":"ref8\/cit8","doi-asserted-by":"publisher","DOI":"10.1007\/bf02163668"},{"key":"ref9\/cit9","doi-asserted-by":"publisher","DOI":"10.1038\/nature23481"},{"key":"ref10\/cit10","doi-asserted-by":"publisher","DOI":"10.1016\/s1570-9639(03)00043-8"},{"key":"ref11\/cit11","doi-asserted-by":"publisher","DOI":"10.1016\/j.cbpa.2005.08.017"},{"key":"ref12\/cit12","doi-asserted-by":"publisher","DOI":"10.1016\/j.cbpa.2012.09.015"},{"key":"ref13\/cit13","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.nutr.012809.104810"},{"key":"ref14\/cit14","doi-asserted-by":"publisher","DOI":"10.1093\/emboj\/cdg395"},{"key":"ref15\/cit15","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.m114.599589"},{"key":"ref16\/cit16","doi-asserted-by":"publisher","DOI":"10.1038\/nature25460"},{"key":"ref17\/cit17","doi-asserted-by":"publisher","DOI":"10.1158\/0008-5472.can-15-2527"},{"key":"ref18\/cit18","doi-asserted-by":"publisher","DOI":"10.1016\/j.molcel.2015.08.020"},{"key":"ref19\/cit19","doi-asserted-by":"publisher","DOI":"10.1186\/s41021-020-00160-4"},{"key":"ref20\/cit20","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-017-11289-8"},{"key":"ref21\/cit21","doi-asserted-by":"publisher","DOI":"10.1111\/jnc.12356"},{"key":"ref22\/cit22","doi-asserted-by":"publisher","DOI":"10.1126\/sciadv.abd7197"},{"key":"ref23\/cit23","doi-asserted-by":"publisher","DOI":"10.1016\/j.molcel.2020.10.012"},{"key":"ref24\/cit24","doi-asserted-by":"publisher","DOI":"10.1038\/170976a0"},{"key":"ref25\/cit25","doi-asserted-by":"publisher","DOI":"10.1146\/annurev-physiol-022516-034055"},{"key":"ref26\/cit26","doi-asserted-by":"publisher","DOI":"10.1021\/acs.accounts.9b00386"},{"key":"ref27\/cit27","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.5b05340"},{"key":"ref28\/cit28","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.5b05339"},{"key":"ref29\/cit29","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.6b12460"},{"key":"ref30\/cit30","doi-asserted-by":"publisher","DOI":"10.1039\/c7sc00748e"},{"key":"ref31\/cit31","doi-asserted-by":"publisher","DOI":"10.1039\/c6sc01503d"},{"key":"ref32\/cit32","doi-asserted-by":"publisher","DOI":"10.1002\/anie.201802143"},{"key":"ref33\/cit33","doi-asserted-by":"publisher","DOI":"10.1002\/anie.201705264"},{"key":"ref34\/cit34","doi-asserted-by":"publisher","DOI":"10.1038\/nchem.2645"},{"key":"ref35\/cit35","doi-asserted-by":"publisher","DOI":"10.1038\/srep01807"},{"key":"ref36\/cit36","doi-asserted-by":"publisher","DOI":"10.1021\/ac00258a001"},{"key":"ref37\/cit37","first-page":"266","volume":"29","author":"Deitrich R.","year":"2006","journal-title":"Alcohol Res. Health"},{"key":"ref38\/cit38","doi-asserted-by":"publisher","DOI":"10.2174\/156720205774962647"},{"key":"ref39\/cit39","doi-asserted-by":"publisher","DOI":"10.1007\/s12035-014-8752-3"},{"key":"ref40\/cit40","doi-asserted-by":"publisher","DOI":"10.2174\/1871527319666200303121016"},{"key":"ref41\/cit41","doi-asserted-by":"publisher","DOI":"10.1016\/j.freeradbiomed.2020.12.002"},{"key":"ref42\/cit42","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbrc.2005.02.121"},{"key":"ref43\/cit43","doi-asserted-by":"publisher","DOI":"10.1016\/0006-2952(84)90526-4"},{"key":"ref44\/cit44","doi-asserted-by":"publisher","DOI":"10.3109\/10408449009029329"},{"key":"ref45\/cit45","doi-asserted-by":"publisher","DOI":"10.1126\/science.1158554"},{"key":"ref46\/cit46","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-019-09897-1"}],"container-title":["Analytical Chemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acs.analchem.1c04520","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,4,25]],"date-time":"2023-04-25T16:50:45Z","timestamp":1682441445000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/acs.analchem.1c04520"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,12,28]]},"references-count":46,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2022,1,18]]}},"alternative-id":["10.1021\/acs.analchem.1c04520"],"URL":"https:\/\/doi.org\/10.1021\/acs.analchem.1c04520","relation":{},"ISSN":["0003-2700","1520-6882"],"issn-type":[{"value":"0003-2700","type":"print"},{"value":"1520-6882","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,12,28]]}}}