{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,4]],"date-time":"2026-07-04T18:24:48Z","timestamp":1783189488516,"version":"3.54.6"},"reference-count":48,"publisher":"American Chemical Society (ACS)","issue":"42","license":[{"start":{"date-parts":[[2022,10,12]],"date-time":"2022-10-12T00:00:00Z","timestamp":1665532800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2022,10,12]],"date-time":"2022-10-12T00:00:00Z","timestamp":1665532800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2022,10,12]],"date-time":"2022-10-12T00:00:00Z","timestamp":1665532800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-045"}],"funder":[{"DOI":"10.13039\/501100000925","name":"National Health and Medical Research Council","doi-asserted-by":"publisher","award":["APP1111216"],"award-info":[{"award-number":["APP1111216"]}],"id":[{"id":"10.13039\/501100000925","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000925","name":"National Health and Medical Research Council","doi-asserted-by":"publisher","award":["APP1173669"],"award-info":[{"award-number":["APP1173669"]}],"id":[{"id":"10.13039\/501100000925","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000923","name":"Australian Research Council","doi-asserted-by":"publisher","award":["DP160102836"],"award-info":[{"award-number":["DP160102836"]}],"id":[{"id":"10.13039\/501100000923","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000923","name":"Australian Research Council","doi-asserted-by":"publisher","award":["DP210103151"],"award-info":[{"award-number":["DP210103151"]}],"id":[{"id":"10.13039\/501100000923","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100022712","name":"Mark Hughes Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100022712","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100015539","name":"Australian Government","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100015539","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100008018","name":"Victorian Cancer Agency","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100008018","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["12074069"],"award-info":[{"award-number":["12074069"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["22204055"],"award-info":[{"award-number":["22204055"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100013026","name":"Hunter Cancer Research Alliance","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100013026","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Anal. Chem."],"published-print":{"date-parts":[[2022,10,25]]},"DOI":"10.1021\/acs.analchem.2c02398","type":"journal-article","created":{"date-parts":[[2022,10,12]],"date-time":"2022-10-12T10:18:22Z","timestamp":1665569902000},"page":"14573-14582","source":"Crossref","is-referenced-by-count":43,"title":["SERS Multiplex Profiling of Melanoma Circulating Tumor Cells for Predicting the Response to Immune Checkpoint Blockade Therapy"],"prefix":"10.1021","volume":"94","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3777-2245","authenticated-orcid":true,"given":"Junrong","family":"Li","sequence":"first","affiliation":[{"name":"Key Laboratory of Pesticide and Chemical Biology, Ministry of Education, College of Chemistry, Central China Normal University, Wuhan430079, P. R. China"},{"name":"Centre for Personalized Nanomedicine, Australian Institute for Bioengineering and Nanotechnology, The University of Queensland, Brisbane, QLD4072, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9569-0478","authenticated-orcid":true,"given":"Alain","family":"Wuethrich","sequence":"additional","affiliation":[{"name":"Centre for Personalized Nanomedicine, Australian Institute for Bioengineering and Nanotechnology, The University of Queensland, Brisbane, QLD4072, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5766-3468","authenticated-orcid":true,"given":"Zhen","family":"Zhang","sequence":"additional","affiliation":[{"name":"Centre for Personalized Nanomedicine, Australian Institute for Bioengineering and Nanotechnology, The University of Queensland, Brisbane, QLD4072, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jing","family":"Wang","sequence":"additional","affiliation":[{"name":"Key Laboratory of OptoElectronic Science and Technology for Medicine of Ministry of Education, Fujian Provincial Key Laboratory of Photonics Technology, Fujian Normal University, Fuzhou350007, P. R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lynlee L.","family":"Lin","sequence":"additional","affiliation":[{"name":"Dermatology Research Centre, The University of Queensland Diamantina Institute, The University of Queensland, Brisbane, QLD4102, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andreas","family":"Behren","sequence":"additional","affiliation":[{"name":"Oliva Newton-John Cancer Research Institute, School of Cancer Medicine, La Trobe University, Heidelberg, VIC3086, Australia"},{"name":"Department of Medicine, University of Melbourne, Heidelberg, VIC3010, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3627-7397","authenticated-orcid":true,"given":"Yuling","family":"Wang","sequence":"additional","affiliation":[{"name":"School of Natural Sciences, Faculty of Science and Engineering, Macquarie University, Sydney, NSW2109, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5516-1280","authenticated-orcid":true,"given":"Matt","family":"Trau","sequence":"additional","affiliation":[{"name":"Centre for Personalized Nanomedicine, Australian Institute for Bioengineering and Nanotechnology, The University of Queensland, Brisbane, QLD4072, Australia"},{"name":"School of Chemistry and Molecular Biosciences, The University of Queensland, Brisbane, QLD4072, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2022,10,12]]},"reference":[{"key":"ref1\/cit1","doi-asserted-by":"publisher","DOI":"10.1126\/science.aar4060"},{"key":"ref2\/cit2","doi-asserted-by":"publisher","DOI":"10.3390\/cancers12030738"},{"key":"ref3\/cit3","doi-asserted-by":"publisher","DOI":"10.1016\/j.ccell.2015.03.001"},{"key":"ref4\/cit4","doi-asserted-by":"publisher","DOI":"10.1016\/j.ctrv.2015.11.001"},{"key":"ref5\/cit5","doi-asserted-by":"publisher","DOI":"10.1038\/ncomms10582"},{"key":"ref6\/cit6","doi-asserted-by":"publisher","DOI":"10.1186\/s13073-020-00743-4"},{"key":"ref7\/cit7","doi-asserted-by":"publisher","DOI":"10.1038\/nature13954"},{"key":"ref8\/cit8","doi-asserted-by":"publisher","DOI":"10.1038\/s41588-018-0312-8"},{"key":"ref9\/cit9","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1406498"},{"key":"ref10\/cit10","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1604958"},{"key":"ref11\/cit11","doi-asserted-by":"publisher","DOI":"10.1177\/1758834017749748"},{"key":"ref12\/cit12","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1500596"},{"key":"ref13\/cit13","doi-asserted-by":"publisher","DOI":"10.1126\/science.aaf8399"},{"key":"ref14\/cit14","doi-asserted-by":"publisher","DOI":"10.1634\/theoncologist.2019-0557"},{"key":"ref15\/cit15","doi-asserted-by":"publisher","DOI":"10.1021\/acs.chemrev.5b00265"},{"key":"ref16\/cit16","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-018-03725-8"},{"key":"ref17\/cit17","doi-asserted-by":"publisher","DOI":"10.1038\/nature14011"},{"key":"ref18\/cit18","doi-asserted-by":"publisher","DOI":"10.1038\/nrclinonc.2017.88"},{"key":"ref19\/cit19","doi-asserted-by":"publisher","DOI":"10.1016\/j.critrevonc.2016.02.001"},{"key":"ref20\/cit20","doi-asserted-by":"publisher","DOI":"10.1002\/onco.13981"},{"key":"ref21\/cit21","doi-asserted-by":"publisher","DOI":"10.1080\/2162402X.2018.1438111"},{"key":"ref22\/cit22","doi-asserted-by":"publisher","DOI":"10.3390\/cancers11060835"},{"key":"ref23\/cit23","doi-asserted-by":"publisher","DOI":"10.1186\/1476-4598-9-301"},{"key":"ref24\/cit24","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2016.08.069"},{"key":"ref25\/cit25","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2017.01.017"},{"key":"ref26\/cit26","doi-asserted-by":"publisher","DOI":"10.1158\/1078-0432.CCR-17-2483"},{"key":"ref27\/cit27","doi-asserted-by":"publisher","DOI":"10.1002\/smll.201704433"},{"key":"ref28\/cit28","doi-asserted-by":"publisher","DOI":"10.1007\/s00216-015-9049-8"},{"key":"ref29\/cit29","doi-asserted-by":"publisher","DOI":"10.1039\/D1LC00516B"},{"key":"ref30\/cit30","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-021-21431-w"},{"key":"ref31\/cit31","doi-asserted-by":"publisher","DOI":"10.1038\/srep04752"},{"key":"ref32\/cit32","doi-asserted-by":"publisher","DOI":"10.1021\/am404406c"},{"key":"ref33\/cit33","doi-asserted-by":"publisher","DOI":"10.1016\/j.talanta.2019.01.085"},{"key":"ref34\/cit34","doi-asserted-by":"publisher","DOI":"10.1021\/acsami.8b10112"},{"key":"ref35\/cit35","doi-asserted-by":"publisher","DOI":"10.1021\/am500506j"},{"key":"ref36\/cit36","doi-asserted-by":"publisher","DOI":"10.1039\/c7cs00158d"},{"key":"ref37\/cit37","doi-asserted-by":"publisher","DOI":"10.1007\/s12274-013-0400-0"},{"key":"ref38\/cit38","doi-asserted-by":"publisher","DOI":"10.1021\/ac503404u"},{"key":"ref39\/cit39","doi-asserted-by":"publisher","DOI":"10.1021\/acs.analchem.9b01191"},{"key":"ref40\/cit40","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcis.2018.11.035"},{"key":"ref41\/cit41","doi-asserted-by":"publisher","DOI":"10.1111\/pcmr.12097"},{"key":"ref42\/cit42","doi-asserted-by":"crossref","DOI":"10.1007\/978-3-642-57049-0","volume-title":"In living color: Protocols in flow cytometry and cell sorting","author":"Diamond R. A.","year":"2000"},{"key":"ref43\/cit43","doi-asserted-by":"publisher","DOI":"10.1002\/smtd.201800474"},{"key":"ref44\/cit44","doi-asserted-by":"publisher","DOI":"10.1021\/acsami.9b18410"},{"key":"ref45\/cit45","doi-asserted-by":"publisher","DOI":"10.1002\/advs.202001581"},{"key":"ref46\/cit46","doi-asserted-by":"publisher","DOI":"10.1038\/nprot.2014.044"},{"key":"ref47\/cit47","doi-asserted-by":"publisher","DOI":"10.1039\/D1LC00546D"},{"key":"ref48\/cit48","doi-asserted-by":"publisher","DOI":"10.1039\/C9LC01122F"}],"container-title":["Analytical Chemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acs.analchem.2c02398","content-type":"application\/pdf","content-version":"vor","intended-application":"unspecified"},{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acs.analchem.2c02398","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,4,28]],"date-time":"2023-04-28T02:31:25Z","timestamp":1682649085000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/acs.analchem.2c02398"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,10,12]]},"references-count":48,"journal-issue":{"issue":"42","published-print":{"date-parts":[[2022,10,25]]}},"alternative-id":["10.1021\/acs.analchem.2c02398"],"URL":"https:\/\/doi.org\/10.1021\/acs.analchem.2c02398","relation":{},"ISSN":["0003-2700","1520-6882"],"issn-type":[{"value":"0003-2700","type":"print"},{"value":"1520-6882","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,10,12]]}}}