{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T04:13:05Z","timestamp":1790741585587,"version":"4.1.0"},"reference-count":36,"publisher":"American Chemical Society (ACS)","issue":"31","license":[{"start":{"date-parts":[[2023,7,28]],"date-time":"2023-07-28T00:00:00Z","timestamp":1690502400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2023,7,28]],"date-time":"2023-07-28T00:00:00Z","timestamp":1690502400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2023,7,28]],"date-time":"2023-07-28T00:00:00Z","timestamp":1690502400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-045"}],"funder":[{"DOI":"10.13039\/501100011496","name":"Science and Technology Bureau, Changsha","doi-asserted-by":"publisher","award":["kq2001031"],"award-info":[{"award-number":["kq2001031"]}],"id":[{"id":"10.13039\/501100011496","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004735","name":"Natural Science Foundation of?Hunan Province","doi-asserted-by":"publisher","award":["2020JJ5698"],"award-info":[{"award-number":["2020JJ5698"]}],"id":[{"id":"10.13039\/501100004735","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004735","name":"Natural Science Foundation of?Hunan Province","doi-asserted-by":"publisher","award":["2020JJ9047"],"award-info":[{"award-number":["2020JJ9047"]}],"id":[{"id":"10.13039\/501100004735","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004735","name":"Natural Science Foundation of?Hunan Province","doi-asserted-by":"publisher","award":["2021JJ30800"],"award-info":[{"award-number":["2021JJ30800"]}],"id":[{"id":"10.13039\/501100004735","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003453","name":"Natural Science Foundation of Guangdong Province","doi-asserted-by":"publisher","award":["2021A1515010526"],"award-info":[{"award-number":["2021A1515010526"]}],"id":[{"id":"10.13039\/501100003453","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100016104","name":"Key Project of Research and Development Plan of Hunan Province","doi-asserted-by":"publisher","award":["2020SK2137"],"award-info":[{"award-number":["2020SK2137"]}],"id":[{"id":"10.13039\/100016104","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Stem Cell New Drug, Innovation Hunan Team","award":["2019RS1088"],"award-info":[{"award-number":["2019RS1088"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Anal. Chem."],"published-print":{"date-parts":[[2023,8,8]]},"DOI":"10.1021\/acs.analchem.3c01876","type":"journal-article","created":{"date-parts":[[2023,7,28]],"date-time":"2023-07-28T12:47:17Z","timestamp":1690548437000},"page":"11741-11750","source":"Crossref","is-referenced-by-count":20,"title":["A Rationally Designed CRISPR\/Cas12a Assay Using a Multimodal Reporter for Various Readouts"],"prefix":"10.1021","volume":"95","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7880-643X","authenticated-orcid":true,"given":"Jean","family":"de Dieu Habimana","sequence":"first","affiliation":[{"name":"CAS Key Laboratory of Regenerative Biology, Guangdong Provincial Key Laboratory of Stem Cell and Regenerative Medicine, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou 510530, China"},{"name":"University of Chinese Academy of Sciences, 19 Yuquan Road, Shijingshan District, Beijing 100049, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Omar","family":"Mukama","sequence":"additional","affiliation":[{"name":"CAS Key Laboratory of Regenerative Biology, Guangdong Provincial Key Laboratory of Stem Cell and Regenerative Medicine, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou 510530, China"},{"name":"University of Chinese Academy of Sciences, 19 Yuquan Road, Shijingshan District, Beijing 100049, China"},{"name":"Department of Biology, College of Science and Technology, University of Rwanda, Avenue de l\u2019arm\u00e9e, Kigali 3900, Rwanda"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7321-9121","authenticated-orcid":true,"given":"Obed Boadi","family":"Amissah","sequence":"additional","affiliation":[{"name":"CAS Key Laboratory of Regenerative Biology, Guangdong Provincial Key Laboratory of Stem Cell and Regenerative Medicine, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou 510530, China"},{"name":"University of Chinese Academy of Sciences, 19 Yuquan Road, Shijingshan District, Beijing 100049, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yirong","family":"Sun","sequence":"additional","affiliation":[{"name":"CAS Key Laboratory of Regenerative Biology, Guangdong Provincial Key Laboratory of Stem Cell and Regenerative Medicine, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou 510530, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eric","family":"Karangwa","sequence":"additional","affiliation":[{"name":"Research and Development, AAFUD Industry (Zhuhai) Co. Ltd., Zhuhai 519085, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yujie","family":"Liu","sequence":"additional","affiliation":[{"name":"CAS Key Laboratory of Regenerative Biology, Guangdong Provincial Key Laboratory of Stem Cell and Regenerative Medicine, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou 510530, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Samson","family":"Mugisha","sequence":"additional","affiliation":[{"name":"Department of Pathology, University of California, San Diego, 9500 Gilman, La Jolla, California 92093, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Na","family":"Cheng","sequence":"additional","affiliation":[{"name":"Department of Anatomy and Neurobiology, Xiangya School of Medicine, Central South University, Changsha 410013, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ling","family":"Wang","sequence":"additional","affiliation":[{"name":"CAS Key Laboratory of Regenerative Biology, Guangdong Provincial Key Laboratory of Stem Cell and Regenerative Medicine, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou 510530, China"},{"name":"Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei 230026, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jianlin","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Gynecology & Obstetrics, The Second Xiangya Hospital of Central South University, Changsha 410011, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sihao","family":"Deng","sequence":"additional","affiliation":[{"name":"Department of Anatomy and Neurobiology, Xiangya School of Medicine, Central South University, Changsha 410013, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rongqi","family":"Huang","sequence":"additional","affiliation":[{"name":"CAS Key Laboratory of Regenerative Biology, Guangdong Provincial Key Laboratory of Stem Cell and Regenerative Medicine, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou 510530, China"},{"name":"University of Chinese Academy of Sciences, 19 Yuquan Road, Shijingshan District, Beijing 100049, China"},{"name":"Guangzhou Qiyuan Biomedical Co., Ltd., Guangzhou 510530, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhiyuan","family":"Li","sequence":"additional","affiliation":[{"name":"CAS Key Laboratory of Regenerative Biology, Guangdong Provincial Key Laboratory of Stem Cell and Regenerative Medicine, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou 510530, China"},{"name":"University of Chinese Academy of Sciences, 19 Yuquan Road, Shijingshan District, Beijing 100049, China"},{"name":"Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei 230026, China"},{"name":"GZMU-GIBH Joint School of Life Sciences, Guangzhou Medical University, Guangzhou 511436, China"},{"name":"GIBH-HKU Guangdong-Hong Kong Stem Cell and Regenerative Medicine Research Centre, GIBH-CUHK Joint Research Laboratory on Stem Cell and Regenerative Medicine, Guangzhou 511436, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2023,7,28]]},"reference":[{"key":"ref1\/cit2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijfoodmicro.2021.109461"},{"key":"ref2\/cit3","doi-asserted-by":"publisher","DOI":"10.1016\/j.foodcont.2005.10.010"},{"key":"ref3\/cit4","doi-asserted-by":"publisher","DOI":"10.1016\/j.foodres.2021.110298"},{"key":"ref4\/cit5","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijfoodmicro.2021.109366"},{"key":"ref5\/cit6","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijfoodmicro.2021.109319"},{"key":"ref6\/cit7","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jafc.7b04820"},{"key":"ref7\/cit8","doi-asserted-by":"publisher","DOI":"10.1016\/j.talanta.2022.123330"},{"key":"ref8\/cit9","doi-asserted-by":"publisher","DOI":"10.1016\/j.vetmic.2016.08.012"},{"key":"ref9\/cit10","doi-asserted-by":"publisher","DOI":"10.3168\/jds.2016-11700"},{"key":"ref10\/cit11","doi-asserted-by":"publisher","DOI":"10.1111\/lam.12590"},{"key":"ref11\/cit12","doi-asserted-by":"publisher","DOI":"10.1016\/j.bios.2022.114033"},{"key":"ref12\/cit13","doi-asserted-by":"publisher","DOI":"10.1016\/j.aca.2022.339541"},{"key":"ref13\/cit14","doi-asserted-by":"publisher","DOI":"10.3390\/bios12010011"},{"key":"ref14\/cit15","doi-asserted-by":"publisher","DOI":"10.1007\/s40820-022-00888-4"},{"key":"ref15\/cit16","doi-asserted-by":"publisher","DOI":"10.1126\/science.aam9321"},{"key":"ref16\/cit17","doi-asserted-by":"publisher","DOI":"10.1126\/science.aar6245"},{"key":"ref17\/cit18","doi-asserted-by":"publisher","DOI":"10.1038\/s41422-018-0022-x"},{"key":"ref18\/cit19","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-020-18615-1"},{"key":"ref19\/cit20","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhazmat.2022.130234"},{"key":"ref20\/cit21","doi-asserted-by":"publisher","DOI":"10.1021\/acssensors.0c01984"},{"key":"ref21\/cit22","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-021-21996-6"},{"key":"ref22\/cit23","doi-asserted-by":"publisher","DOI":"10.1016\/j.bioactmat.2021.05.005"},{"key":"ref23\/cit24","doi-asserted-by":"publisher","DOI":"10.1016\/j.bios.2021.113646"},{"key":"ref24\/cit25","doi-asserted-by":"publisher","DOI":"10.1039\/D1CC02546E"},{"key":"ref25\/cit26","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhazmat.2023.131195"},{"key":"ref26\/cit27","doi-asserted-by":"publisher","DOI":"10.1021\/acs.analchem.1c02478"},{"key":"ref27\/cit28","doi-asserted-by":"publisher","DOI":"10.1038\/s41565-022-01179-0"},{"key":"ref28\/cit29","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.2c07625"},{"key":"ref29\/cit30","doi-asserted-by":"publisher","DOI":"10.1016\/j.bios.2021.113073"},{"key":"ref30\/cit31","doi-asserted-by":"publisher","DOI":"10.1016\/j.aca.2021.339180"},{"key":"ref31\/cit32","doi-asserted-by":"publisher","DOI":"10.1016\/j.bios.2020.112143"},{"key":"ref32\/cit33","doi-asserted-by":"publisher","DOI":"10.1016\/j.bios.2022.114939"},{"key":"ref33\/cit34","doi-asserted-by":"publisher","DOI":"10.1016\/j.snb.2020.128119"},{"key":"ref34\/cit35","doi-asserted-by":"publisher","DOI":"10.1016\/j.snb.2022.132301"},{"key":"ref35\/cit36","doi-asserted-by":"publisher","DOI":"10.1016\/j.bios.2022.114377"},{"key":"ref36\/cit37","doi-asserted-by":"publisher","DOI":"10.1016\/j.snb.2021.130630"}],"container-title":["Analytical Chemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acs.analchem.3c01876","content-type":"application\/pdf","content-version":"vor","intended-application":"unspecified"},{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acs.analchem.3c01876","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,8]],"date-time":"2023-08-08T08:15:20Z","timestamp":1691482520000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/acs.analchem.3c01876"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,7,28]]},"references-count":36,"journal-issue":{"issue":"31","published-print":{"date-parts":[[2023,8,8]]}},"alternative-id":["10.1021\/acs.analchem.3c01876"],"URL":"https:\/\/doi.org\/10.1021\/acs.analchem.3c01876","relation":{},"ISSN":["0003-2700","1520-6882"],"issn-type":[{"value":"0003-2700","type":"print"},{"value":"1520-6882","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,7,28]]}}}