{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T08:45:55Z","timestamp":1790671555995,"version":"4.1.0"},"reference-count":70,"publisher":"American Chemical Society (ACS)","issue":"24","license":[{"start":{"date-parts":[[2025,6,9]],"date-time":"2025-06-09T00:00:00Z","timestamp":1749427200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100000781","name":"European Research Council","doi-asserted-by":"publisher","award":["101003052"],"award-info":[{"award-number":["101003052"]}],"id":[{"id":"10.13039\/501100000781","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004836","name":"Danmarks Frie Forskningsfond","doi-asserted-by":"publisher","award":["0602-02100B"],"award-info":[{"award-number":["0602-02100B"]}],"id":[{"id":"10.13039\/501100004836","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004836","name":"Danmarks Frie Forskningsfond","doi-asserted-by":"publisher","award":["060202740B"],"award-info":[{"award-number":["060202740B"]}],"id":[{"id":"10.13039\/501100004836","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Anal. Chem."],"published-print":{"date-parts":[[2025,6,24]]},"DOI":"10.1021\/acs.analchem.4c06230","type":"journal-article","created":{"date-parts":[[2025,6,9]],"date-time":"2025-06-09T10:22:02Z","timestamp":1749464522000},"page":"12503-12512","source":"Crossref","is-referenced-by-count":7,"title":["Development of a Thiol\u2013ene Microfluidic Chip for Hydrogen\/Deuterium Exchange Mass Spectrometry (HDX-MS)"],"prefix":"10.1021","volume":"97","author":[{"ORCID":"https:\/\/orcid.org\/0009-0002-8123-5241","authenticated-orcid":true,"given":"Anton B.","family":"Hansen","sequence":"first","affiliation":[{"name":"Protein Analysis Group, Department of Pharmacy","place":["Copenhagen, Denmark"]},{"name":"University of Copenhagen","place":["Copenhagen, Denmark"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7665-7119","authenticated-orcid":true,"given":"Rasmus R.","family":"Svejdal","sequence":"additional","affiliation":[{"name":"Protein Analysis Group, Department of Pharmacy","place":["Copenhagen, Denmark"]},{"name":"University of Copenhagen","place":["Copenhagen, Denmark"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jordan T.","family":"Aerts","sequence":"additional","affiliation":[{"name":"Protein Analysis Group, Department of Pharmacy","place":["Copenhagen, Denmark"]},{"name":"University of Copenhagen","place":["Copenhagen, Denmark"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vanessa B. P.","family":"Stahlhut","sequence":"additional","affiliation":[{"name":"Protein Analysis Group, Department of Pharmacy","place":["Copenhagen, Denmark"]},{"name":"University of Copenhagen","place":["Copenhagen, Denmark"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daria","family":"Harmash","sequence":"additional","affiliation":[{"name":"Protein Analysis Group, Department of Pharmacy","place":["Copenhagen, Denmark"]},{"name":"University of Copenhagen","place":["Copenhagen, Denmark"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Minna","family":"Hamidi","sequence":"additional","affiliation":[{"name":"Protein Analysis Group, Department of Pharmacy","place":["Copenhagen, Denmark"]},{"name":"University of Copenhagen","place":["Copenhagen, Denmark"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Drago","family":"Sticker","sequence":"additional","affiliation":[{"name":"Department of Pharmacy","place":["Copenhagen, Denmark"]},{"name":"University of Copenhagen","place":["Copenhagen, Denmark"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1065-1985","authenticated-orcid":true,"given":"J\u00f6rg P.","family":"Kutter","sequence":"additional","affiliation":[{"name":"Department of Pharmacy","place":["Copenhagen, Denmark"]},{"name":"University of Copenhagen","place":["Copenhagen, Denmark"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6337-5489","authenticated-orcid":true,"given":"Kasper D.","family":"Rand","sequence":"additional","affiliation":[{"name":"Protein Analysis Group, Department of Pharmacy","place":["Copenhagen, Denmark"]},{"name":"University of Copenhagen","place":["Copenhagen, Denmark"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2025,6,9]]},"reference":[{"key":"ref1\/cit1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M110.180646"},{"key":"ref2\/cit2","doi-asserted-by":"publisher","DOI":"10.1038\/nsmb.2467"},{"key":"ref3\/cit3","doi-asserted-by":"publisher","DOI":"10.1007\/s13361-018-2087-7"},{"key":"ref4\/cit4","doi-asserted-by":"publisher","DOI":"10.1038\/s41596-019-0219-6"},{"key":"ref5\/cit5","doi-asserted-by":"publisher","DOI":"10.1016\/j.trac.2018.06.008"},{"key":"ref6\/cit6","doi-asserted-by":"publisher","DOI":"10.1021\/ac0518497"},{"key":"ref7\/cit7","doi-asserted-by":"publisher","DOI":"10.1007\/s13361-012-0476-x"},{"key":"ref8\/cit8","doi-asserted-by":"publisher","DOI":"10.1007\/s13361-013-0639-4"},{"key":"ref9\/cit9","doi-asserted-by":"publisher","DOI":"10.1002\/pro.5560020404"},{"key":"ref10\/cit10","doi-asserted-by":"publisher","DOI":"10.1038\/s41592-019-0459-y"},{"key":"ref11\/cit11","doi-asserted-by":"publisher","DOI":"10.1021\/acs.analchem.6b03951"},{"key":"ref12\/cit12","doi-asserted-by":"publisher","DOI":"10.1007\/s00216-013-7374-3"},{"key":"ref13\/cit13","doi-asserted-by":"publisher","DOI":"10.1021\/ac0710782"},{"key":"ref14\/cit14","doi-asserted-by":"publisher","DOI":"10.1021\/ac302488h"},{"key":"ref15\/cit15","doi-asserted-by":"publisher","DOI":"10.1021\/ac300268r"},{"key":"ref16\/cit16","doi-asserted-by":"publisher","DOI":"10.1021\/ja507880w"},{"key":"ref17\/cit17","doi-asserted-by":"publisher","DOI":"10.1016\/j.chroma.2017.05.067"},{"key":"ref18\/cit18","doi-asserted-by":"publisher","DOI":"10.1021\/acs.analchem.8b01864"},{"key":"ref19\/cit19","doi-asserted-by":"publisher","DOI":"10.1016\/j.str.2018.08.006"},{"key":"ref20\/cit20","doi-asserted-by":"publisher","DOI":"10.1016\/j.aca.2020.11.022"},{"key":"ref21\/cit21","doi-asserted-by":"publisher","DOI":"10.1021\/acs.analchem.2c03893"},{"key":"ref22\/cit22","doi-asserted-by":"publisher","DOI":"10.1021\/jasms.2c00096"},{"key":"ref23\/cit23","doi-asserted-by":"publisher","DOI":"10.1021\/jasms.3c00243"},{"key":"ref24\/cit24","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9673(01)82158-0"},{"key":"ref25\/cit25","doi-asserted-by":"publisher","DOI":"10.1016\/j.jasms.2005.10.009"},{"key":"ref26\/cit26","doi-asserted-by":"publisher","DOI":"10.1016\/j.chroma.2022.463742"},{"key":"ref27\/cit27","doi-asserted-by":"publisher","DOI":"10.1021\/acs.analchem.8b03050"},{"key":"ref28\/cit28","doi-asserted-by":"publisher","DOI":"10.1016\/j.chroma.2015.12.048"},{"key":"ref29\/cit29","doi-asserted-by":"publisher","DOI":"10.1039\/c3lc00007a"},{"key":"ref30\/cit30","doi-asserted-by":"publisher","DOI":"10.1021\/acs.analchem.5b01179"},{"key":"ref31\/cit31","doi-asserted-by":"publisher","DOI":"10.1021\/acs.analchem.2c00077"},{"key":"ref32\/cit32","doi-asserted-by":"publisher","DOI":"10.1007\/s00216-014-7988-0"},{"key":"ref33\/cit33","doi-asserted-by":"publisher","DOI":"10.1021\/acs.analchem.9b04711"},{"key":"ref34\/cit34","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1007\/128_2011_147","volume-title":"Microfluidics: Technologies and Applications","author":"Zhang C.","year":"2011"},{"key":"ref35\/cit35","doi-asserted-by":"publisher","DOI":"10.1016\/j.aca.2020.09.062"},{"key":"ref36\/cit36","doi-asserted-by":"publisher","DOI":"10.1021\/ac102437z"},{"key":"ref37\/cit37","doi-asserted-by":"publisher","DOI":"10.1021\/acs.analchem.9b05206"},{"key":"ref38\/cit38","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-019-09533-y"},{"key":"ref39\/cit39","doi-asserted-by":"publisher","DOI":"10.1021\/acs.analchem.6b05103"},{"key":"ref40\/cit40","doi-asserted-by":"publisher","DOI":"10.1039\/C5LC00224A"},{"key":"ref41\/cit41","doi-asserted-by":"publisher","DOI":"10.1002\/rcm.4391"},{"key":"ref42\/cit42","doi-asserted-by":"publisher","DOI":"10.1021\/acs.analchem.1c05232"},{"key":"ref43\/cit43","doi-asserted-by":"publisher","DOI":"10.1021\/ar300314s"},{"key":"ref44\/cit44","doi-asserted-by":"publisher","DOI":"10.1088\/0960-1317\/23\/3\/037002"},{"key":"ref45\/cit45","doi-asserted-by":"publisher","DOI":"10.1039\/c1lc20388f"},{"key":"ref46\/cit46","doi-asserted-by":"publisher","DOI":"10.1021\/acssensors.0c02704"},{"key":"ref47\/cit47","doi-asserted-by":"publisher","DOI":"10.1021\/acsami.9b22050"},{"key":"ref48\/cit48","doi-asserted-by":"publisher","DOI":"10.1088\/0960-1317\/26\/7\/075014"},{"key":"ref49\/cit49","doi-asserted-by":"publisher","DOI":"10.1039\/C8LC01260A"},{"key":"ref50\/cit50","doi-asserted-by":"publisher","DOI":"10.1186\/s40824-015-0041-3"},{"key":"ref51\/cit51","doi-asserted-by":"publisher","DOI":"10.1002\/elps.201300271"},{"key":"ref52\/cit52","doi-asserted-by":"publisher","DOI":"10.1016\/j.aca.2020.01.025"},{"key":"ref53\/cit53","doi-asserted-by":"publisher","DOI":"10.1016\/j.eurpolymj.2019.109456"},{"key":"ref54\/cit54","doi-asserted-by":"publisher","DOI":"10.1039\/C8AY00646F"},{"key":"ref55\/cit55","doi-asserted-by":"publisher","DOI":"10.1016\/j.chroma.2017.03.018"},{"key":"ref56\/cit56","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1232301100"},{"key":"ref57\/cit57","doi-asserted-by":"publisher","DOI":"10.1021\/ac501849n"},{"key":"ref58\/cit58","doi-asserted-by":"publisher","DOI":"10.1021\/acs.analchem.2c01446"},{"key":"ref62\/cit62","doi-asserted-by":"publisher","DOI":"10.1146\/annurev-anchem-062011-143113"},{"key":"ref63\/cit63","doi-asserted-by":"publisher","DOI":"10.1002\/prot.340170110"},{"key":"ref64\/cit64","doi-asserted-by":"publisher","DOI":"10.1021\/jasms.0c00260"},{"key":"ref65\/cit65","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9258(18)97115-2"},{"key":"ref66\/cit66","doi-asserted-by":"publisher","DOI":"10.1021\/bi00317a023"},{"key":"ref67\/cit67","doi-asserted-by":"publisher","DOI":"10.1021\/acs.biochem.0c00308"},{"key":"ref68\/cit68","doi-asserted-by":"publisher","DOI":"10.1007\/s13361-013-0647-4"},{"key":"ref69\/cit69","doi-asserted-by":"publisher","DOI":"10.1107\/S2059798316009049"},{"key":"ref70\/cit70","doi-asserted-by":"publisher","DOI":"10.1016\/0003-2697(85)90033-8"},{"key":"ref71\/cit71","doi-asserted-by":"publisher","DOI":"10.1021\/acs.analchem.5b00831"},{"key":"ref72\/cit72","doi-asserted-by":"publisher","DOI":"10.1021\/acs.analchem.9b00973"},{"key":"ref73\/cit73","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-024-46610-3"}],"container-title":["Analytical Chemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acs.analchem.4c06230","content-type":"application\/pdf","content-version":"vor","intended-application":"unspecified"},{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acs.analchem.4c06230","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,6,24]],"date-time":"2025-06-24T04:12:18Z","timestamp":1750738338000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/acs.analchem.4c06230"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,6,9]]},"references-count":70,"journal-issue":{"issue":"24","published-print":{"date-parts":[[2025,6,24]]}},"alternative-id":["10.1021\/acs.analchem.4c06230"],"URL":"https:\/\/doi.org\/10.1021\/acs.analchem.4c06230","relation":{},"ISSN":["0003-2700","1520-6882"],"issn-type":[{"value":"0003-2700","type":"print"},{"value":"1520-6882","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,6,9]]}}}