{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,21]],"date-time":"2026-07-21T16:42:30Z","timestamp":1784652150701,"version":"3.55.0"},"reference-count":56,"publisher":"American Chemical Society (ACS)","issue":"16","funder":[{"DOI":"10.13039\/100000050","name":"National Heart, Lung, and Blood Institute","doi-asserted-by":"publisher","award":["R01 HL096971"],"award-info":[{"award-number":["R01 HL096971"]}],"id":[{"id":"10.13039\/100000050","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000050","name":"National Heart, Lung, and Blood Institute","doi-asserted-by":"publisher","award":["R01 HL109810"],"award-info":[{"award-number":["R01 HL109810"]}],"id":[{"id":"10.13039\/100000050","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Anal. Chem."],"published-print":{"date-parts":[[2015,8,18]]},"DOI":"10.1021\/acs.analchem.5b01745","type":"journal-article","created":{"date-parts":[[2015,7,19]],"date-time":"2015-07-19T19:29:18Z","timestamp":1437334158000},"page":"8399-8406","source":"Crossref","is-referenced-by-count":30,"title":["Effective Top-Down LC\/MS+ Method for Assessing Actin Isoforms as a Potential Cardiac Disease Marker"],"prefix":"10.1021","volume":"87","author":[{"given":"Yi-Chen","family":"Chen","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Serife","family":"Ayaz-Guner","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ying","family":"Peng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicole M.","family":"Lane","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matthew R.","family":"Locher","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takushi","family":"Kohmoto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lars","family":"Larsson","sequence":"additional","affiliation":[{"name":"Department\rof Physiology and Pharmacology, Department of Clinical Neuroscience, Karolinska Institutet, SE-171 77 Stockholm, Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Richard L.","family":"Moss","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ying","family":"Ge","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2015,7,31]]},"reference":[{"key":"ref1\/cit1","doi-asserted-by":"publisher","DOI":"10.1161\/01.RES.74.4.740"},{"key":"ref2\/cit2","doi-asserted-by":"publisher","DOI":"10.1161\/01.RES.0000127125.61647.4F"},{"key":"ref3\/cit3","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.bb.21.060192.000405"},{"key":"ref4\/cit4","doi-asserted-by":"crossref","first-page":"1838","DOI":"10.1016\/S0021-9258(17)36017-9","volume":"261","author":"Vandekerckhove J.","year":"1986","journal-title":"J. Biol. Chem."},{"key":"ref5\/cit5","doi-asserted-by":"publisher","DOI":"10.1007\/s10974-010-9224-7"},{"key":"ref6\/cit6","doi-asserted-by":"publisher","DOI":"10.1161\/01.RES.85.10.e51"},{"key":"ref7\/cit7","doi-asserted-by":"publisher","DOI":"10.1002\/path.1311"},{"key":"ref8\/cit8","doi-asserted-by":"publisher","DOI":"10.1002\/rcm.1075"},{"key":"ref9\/cit9","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-2828(86)80013-X"},{"key":"ref10\/cit10","doi-asserted-by":"publisher","DOI":"10.1152\/ajpheart.01057.2008"},{"key":"ref11\/cit11","doi-asserted-by":"publisher","DOI":"10.1172\/JCI115295"},{"key":"ref12\/cit12","doi-asserted-by":"publisher","DOI":"10.1111\/j.1582-4934.2008.00523.x"},{"key":"ref13\/cit13","doi-asserted-by":"publisher","DOI":"10.1016\/j.nmd.2008.09.010"},{"key":"ref14\/cit14","doi-asserted-by":"publisher","DOI":"10.1111\/j.1432-0436.1979.tb01021.x"},{"key":"ref15\/cit15","doi-asserted-by":"publisher","DOI":"10.1016\/j.febslet.2009.10.036"},{"key":"ref16\/cit16","doi-asserted-by":"crossref","first-page":"1720","DOI":"10.1128\/MCB.19.3.1720","volume":"19","author":"Gygi S. P.","year":"1999","journal-title":"Mol. Cell. Biol."},{"key":"ref17\/cit17","doi-asserted-by":"publisher","DOI":"10.1113\/expphysiol.2005.032607"},{"key":"ref18\/cit18","doi-asserted-by":"publisher","DOI":"10.1016\/j.ymeth.2005.11.007"},{"key":"ref19\/cit19","doi-asserted-by":"publisher","DOI":"10.1007\/s12033-013-9672-6"},{"key":"ref20\/cit20","doi-asserted-by":"publisher","DOI":"10.1146\/annurev-biochem-110810-095744"},{"key":"ref21\/cit21","doi-asserted-by":"publisher","DOI":"10.1038\/nbt0303-255"},{"key":"ref22\/cit22","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.biochem.70.1.437"},{"key":"ref23\/cit23","doi-asserted-by":"publisher","DOI":"10.1586\/14789450.2014.976559"},{"key":"ref24\/cit24","doi-asserted-by":"publisher","DOI":"10.1002\/pmic.201300432"},{"key":"ref25\/cit25","doi-asserted-by":"publisher","DOI":"10.1038\/nmeth1097"},{"key":"ref26\/cit26","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCGENETICS.110.957829"},{"key":"ref27\/cit27","doi-asserted-by":"publisher","DOI":"10.1021\/pr301054n"},{"key":"ref28\/cit28","doi-asserted-by":"publisher","DOI":"10.1074\/mcp.M114.040675"},{"key":"ref29\/cit29","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M111.293258"},{"key":"ref30\/cit30","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0813369106"},{"key":"ref31\/cit31","doi-asserted-by":"publisher","DOI":"10.1021\/pr200258m"},{"key":"ref32\/cit32","doi-asserted-by":"publisher","DOI":"10.1126\/science.1200729"},{"key":"ref33\/cit33","doi-asserted-by":"publisher","DOI":"10.1074\/mcp.M900516-MCP200"},{"key":"ref34\/cit34","doi-asserted-by":"publisher","DOI":"10.1038\/nature10575"},{"key":"ref35\/cit35","doi-asserted-by":"publisher","DOI":"10.1161\/01.RES.13.3.187"},{"key":"ref36\/cit36","doi-asserted-by":"crossref","first-page":"164","DOI":"10.1016\/0076-6879(82)85020-9","volume":"85","author":"Pardee J. D.","year":"1982","journal-title":"Methods Enzymol."},{"key":"ref37\/cit37","doi-asserted-by":"publisher","DOI":"10.1007\/s10974-015-9404-6"},{"key":"ref38\/cit38","doi-asserted-by":"publisher","DOI":"10.1007\/s13361-013-0789-4"},{"key":"ref39\/cit39","doi-asserted-by":"publisher","DOI":"10.1016\/S1044-0305(99)00157-9"},{"key":"ref40\/cit40","doi-asserted-by":"publisher","DOI":"10.1016\/0006-291X(67)90229-X"},{"key":"ref41\/cit41","doi-asserted-by":"publisher","DOI":"10.1042\/bj1050361"},{"key":"ref42\/cit42","doi-asserted-by":"publisher","DOI":"10.1006\/jmbi.2002.5436"},{"key":"ref43\/cit43","doi-asserted-by":"publisher","DOI":"10.1016\/j.stem.2014.11.009"},{"key":"ref44\/cit44","doi-asserted-by":"publisher","DOI":"10.1016\/j.jasms.2010.02.005"},{"key":"ref45\/cit45","doi-asserted-by":"publisher","DOI":"10.1038\/nchembio736"},{"key":"ref46\/cit46","doi-asserted-by":"publisher","DOI":"10.1242\/jcs.03340"},{"key":"ref47\/cit47","doi-asserted-by":"publisher","DOI":"10.1074\/mcp.M200045-MCP200"},{"key":"ref48\/cit48","doi-asserted-by":"publisher","DOI":"10.1002\/pmic.201000190"},{"key":"ref49\/cit49","doi-asserted-by":"publisher","DOI":"10.1007\/s13361-012-0480-1"},{"key":"ref50\/cit50","doi-asserted-by":"publisher","DOI":"10.1016\/j.jasms.2009.01.005"},{"key":"ref51\/cit51","doi-asserted-by":"publisher","DOI":"10.1074\/mcp.M700524-MCP200"},{"key":"ref52\/cit52","doi-asserted-by":"publisher","DOI":"10.1021\/ac0600050"},{"key":"ref53\/cit53","doi-asserted-by":"publisher","DOI":"10.1016\/S0735-1097(01)01509-1"},{"key":"ref54\/cit54","doi-asserted-by":"publisher","DOI":"10.1007\/s10741-007-9034-1"},{"key":"ref55\/cit55","doi-asserted-by":"publisher","DOI":"10.1126\/science.1139089"},{"key":"ref56\/cit56","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.85.2.339"}],"container-title":["Analytical Chemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acs.analchem.5b01745","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,4,14]],"date-time":"2023-04-14T14:53:34Z","timestamp":1681484014000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/acs.analchem.5b01745"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,7,31]]},"references-count":56,"journal-issue":{"issue":"16","published-print":{"date-parts":[[2015,8,18]]}},"alternative-id":["10.1021\/acs.analchem.5b01745"],"URL":"https:\/\/doi.org\/10.1021\/acs.analchem.5b01745","relation":{},"ISSN":["0003-2700","1520-6882"],"issn-type":[{"value":"0003-2700","type":"print"},{"value":"1520-6882","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,7,31]]}}}