{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,10]],"date-time":"2026-10-10T07:07:47Z","timestamp":1791616067271,"version":"4.3.4"},"reference-count":68,"publisher":"American Chemical Society (ACS)","issue":"5","license":[{"start":{"date-parts":[[2027,1,29]],"date-time":"2027-01-29T00:00:00Z","timestamp":1801180800000},"content-version":"vor","delay-in-days":365,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2026,1,29]],"date-time":"2026-01-29T00:00:00Z","timestamp":1769644800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,1,29]],"date-time":"2026-01-29T00:00:00Z","timestamp":1769644800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,1,29]],"date-time":"2026-01-29T00:00:00Z","timestamp":1769644800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-045"}],"funder":[{"DOI":"10.13039\/501100003246","name":"Nederlandse Organisatie voor Wetenschappelijk Onderzoek","doi-asserted-by":"publisher","award":["184.034.019"],"award-info":[{"award-number":["184.034.019"]}],"id":[{"id":"10.13039\/501100003246","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003246","name":"Nederlandse Organisatie voor Wetenschappelijk Onderzoek","doi-asserted-by":"publisher","award":["SPI.2017.028"],"award-info":[{"award-number":["SPI.2017.028"]}],"id":[{"id":"10.13039\/501100003246","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Anal. Chem."],"published-print":{"date-parts":[[2026,2,10]]},"DOI":"10.1021\/acs.analchem.5c04479","type":"journal-article","created":{"date-parts":[[2026,1,29]],"date-time":"2026-01-29T15:56:05Z","timestamp":1769702165000},"page":"3544-3556","source":"Crossref","is-referenced-by-count":3,"title":["Spectral Quality-Guided Optimization of Hybrid EAciD Fragmentation on the ZenoTOF 7600 System Enables Efficient Characterization of the Serum\n                    <i>N<\/i>\n                    -Glycoproteome"],"prefix":"10.1021","volume":"98","author":[{"given":"Shelley","family":"Jager","sequence":"first","affiliation":[{"name":"Biomolecular Mass Spectrometry and Proteomics, Bijvoet Centre for Biomolecular Research and Utrecht Institute for Pharmaceutical Sciences, Utrecht University, Padualaan 8, Utrecht 3584 CH, The Netherlands"},{"name":"Netherlands Proteomic Centre, Padualaan 8, Utrecht 3584 CH, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tatiana M.","family":"Shamorkina","sequence":"additional","affiliation":[{"name":"Biomolecular Mass Spectrometry and Proteomics, Bijvoet Centre for Biomolecular Research and Utrecht Institute for Pharmaceutical Sciences, Utrecht University, Padualaan 8, Utrecht 3584 CH, The Netherlands"},{"name":"Netherlands Proteomic Centre, Padualaan 8, Utrecht 3584 CH, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sibylle M.","family":"Heidelberger","sequence":"additional","affiliation":[{"name":"SCIEX, Alderley Park, Suite 21F18, 21 Mereside, Macclesfield SK10 4TG, United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patrick A.","family":"Pribil","sequence":"additional","affiliation":[{"name":"SCIEX, 71 Four Valley Dr, Concord, Ontario L4K 4 V8, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0594-0993","authenticated-orcid":true,"given":"Douwe","family":"Schulte","sequence":"additional","affiliation":[{"name":"Biomolecular Mass Spectrometry and Proteomics, Bijvoet Centre for Biomolecular Research and Utrecht Institute for Pharmaceutical Sciences, Utrecht University, Padualaan 8, Utrecht 3584 CH, The Netherlands"},{"name":"Netherlands Proteomic Centre, Padualaan 8, Utrecht 3584 CH, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karli R.","family":"Reiding","sequence":"additional","affiliation":[{"name":"Biomolecular Mass Spectrometry and Proteomics, Bijvoet Centre for Biomolecular Research and Utrecht Institute for Pharmaceutical Sciences, Utrecht University, Padualaan 8, Utrecht 3584 CH, The Netherlands"},{"name":"Netherlands Proteomic Centre, Padualaan 8, Utrecht 3584 CH, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2405-4404","authenticated-orcid":true,"given":"Albert J.R.","family":"Heck","sequence":"additional","affiliation":[{"name":"Biomolecular Mass Spectrometry and Proteomics, Bijvoet Centre for Biomolecular Research and Utrecht Institute for Pharmaceutical Sciences, Utrecht University, Padualaan 8, Utrecht 3584 CH, The Netherlands"},{"name":"Netherlands Proteomic Centre, Padualaan 8, Utrecht 3584 CH, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2026,1,29]]},"reference":[{"key":"ref1\/cit1","unstructured":"Varki, A.; Cummings, R. D.; Esko, J. D.; Stanley, P.; Hart, G. W.; Aebi, M.; Mohnen, D.; Kinoshita, T.; Packer, N. H.; Prestegard, J. H.\n                      Essentials of Glycobiology\n                      , 4th ed. ed. Cold Spring Harbor (NY), 2022, pp. 892."},{"key":"ref2\/cit2","doi-asserted-by":"publisher","DOI":"10.1038\/nrm3383"},{"key":"ref3\/cit3","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-024-50338-5"},{"key":"ref4\/cit4","doi-asserted-by":"publisher","DOI":"10.1016\/j.cbpa.2023.102272"},{"key":"ref5\/cit5","doi-asserted-by":"publisher","DOI":"10.1038\/s43586-022-00128-4"},{"key":"ref6\/cit6","doi-asserted-by":"publisher","DOI":"10.1002\/jms.5034"},{"key":"ref7\/cit7","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jproteome.0c00218"},{"key":"ref8\/cit8","doi-asserted-by":"publisher","DOI":"10.1021\/acs.analchem.4c01450"},{"key":"ref9\/cit9","doi-asserted-by":"publisher","DOI":"10.1093\/bfgp\/eln053"},{"key":"ref10\/cit10","doi-asserted-by":"publisher","DOI":"10.1021\/acs.analchem.3c05874"},{"key":"ref11\/cit11","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jproteome.2c00519"},{"key":"ref12\/cit12","doi-asserted-by":"publisher","DOI":"10.1021\/jasms.3c00375"},{"key":"ref13\/cit13","doi-asserted-by":"publisher","DOI":"10.1007\/s13361-015-1308-6"},{"key":"ref14\/cit14","doi-asserted-by":"publisher","DOI":"10.1016\/j.jasms.2007.10.022"},{"key":"ref15\/cit15","doi-asserted-by":"publisher","DOI":"10.1021\/acs.analchem.9b02125"},{"key":"ref16\/cit16","doi-asserted-by":"publisher","DOI":"10.1021\/acs.analchem.7b04810"},{"key":"ref17\/cit17","doi-asserted-by":"publisher","DOI":"10.1021\/acs.analchem.2c04027"},{"key":"ref18\/cit18","doi-asserted-by":"publisher","DOI":"10.1021\/acs.analchem.5c02832"},{"key":"ref19\/cit19","doi-asserted-by":"publisher","DOI":"10.1021\/acs.analchem.2c02215"},{"key":"ref20\/cit20","author":"Jager S.","year":"2024","journal-title":"arXiv"},{"key":"ref21\/cit21","doi-asserted-by":"publisher","DOI":"10.1038\/nbt.2377"},{"key":"ref22\/cit22","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jproteome.0c00544"},{"key":"ref23\/cit23","doi-asserted-by":"publisher","DOI":"10.1038\/s41592-020-0967-9"},{"key":"ref24\/cit24","doi-asserted-by":"publisher","DOI":"10.1016\/j.mcpro.2022.100205"},{"key":"ref25\/cit25","doi-asserted-by":"publisher","DOI":"10.1038\/nmeth.4256"},{"key":"ref26\/cit26","volume-title":"Human Protein Atlas.","author":"Proteinatlas.org","year":"2024"},{"key":"ref27\/cit27","doi-asserted-by":"publisher","DOI":"10.1126\/scisignal.aaz0274"},{"key":"ref28\/cit28","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkz995"},{"key":"ref29\/cit29","doi-asserted-by":"publisher","DOI":"10.1016\/j.trac.2018.09.007"},{"key":"ref30\/cit30","doi-asserted-by":"publisher","DOI":"10.1038\/S41594-025-01485-W"},{"key":"ref31\/cit31","doi-asserted-by":"publisher","DOI":"10.1021\/acs.analchem.3c04484"},{"key":"ref32\/cit32","doi-asserted-by":"publisher","DOI":"10.1021\/ac1027116"},{"key":"ref33\/cit33","doi-asserted-by":"publisher","DOI":"10.2217\/fon.14.202"},{"key":"ref34\/cit34","doi-asserted-by":"publisher","DOI":"10.1016\/S1357-2725(99)00005-9"},{"key":"ref35\/cit35","doi-asserted-by":"publisher","DOI":"10.3233\/CBM-160639"},{"key":"ref36\/cit36","doi-asserted-by":"publisher","DOI":"10.1177\/13.8.740"},{"key":"ref37\/cit37","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2020.00794"},{"key":"ref38\/cit38","doi-asserted-by":"publisher","DOI":"10.2174\/0929867328666210804085636"},{"key":"ref39\/cit39","doi-asserted-by":"publisher","DOI":"10.1016\/j.mcpro.2022.100486"},{"key":"ref40\/cit40","doi-asserted-by":"publisher","DOI":"10.1007\/s13361-018-1909-y"},{"key":"ref41\/cit41","doi-asserted-by":"publisher","DOI":"10.3389\/fchem.2022.920009"},{"key":"ref42\/cit42","doi-asserted-by":"publisher","DOI":"10.1016\/j.aca.2021.339232"},{"key":"ref43\/cit43","doi-asserted-by":"publisher","DOI":"10.1007\/s13361-017-1701-4"},{"key":"ref44\/cit44","doi-asserted-by":"publisher","DOI":"10.1074\/mcp.M000031-MCP201"},{"key":"ref45\/cit45","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jproteome.2c00378"},{"key":"ref46\/cit46","doi-asserted-by":"publisher","DOI":"10.1021\/acs.analchem.2c04581"},{"key":"ref47\/cit47","doi-asserted-by":"publisher","DOI":"10.1002\/elps.201800272"},{"key":"ref48\/cit48","doi-asserted-by":"publisher","DOI":"10.1007\/s13361-015-1183-1"},{"key":"ref49\/cit49","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-019-09222-w"},{"key":"ref50\/cit50","doi-asserted-by":"publisher","DOI":"10.1021\/acs.analchem.5b04218"},{"key":"ref51\/cit51","doi-asserted-by":"publisher","DOI":"10.1021\/acs.analchem.1c04874"},{"key":"ref52\/cit52","doi-asserted-by":"publisher","DOI":"10.1002\/prca.201600028"},{"key":"ref53\/cit53","doi-asserted-by":"publisher","DOI":"10.3390\/ijms25063435"},{"key":"ref54\/cit54","doi-asserted-by":"publisher","DOI":"10.3389\/fonc.2021.622076"},{"key":"ref55\/cit55","doi-asserted-by":"publisher","DOI":"10.1080\/14789450.2023.2265064"},{"key":"ref56\/cit56","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.v22.i42.9288"},{"key":"ref57\/cit57","doi-asserted-by":"publisher","DOI":"10.1084\/jem.20211505"},{"key":"ref58\/cit58","doi-asserted-by":"publisher","DOI":"10.1002\/elps.201700025"},{"key":"ref59\/cit59","doi-asserted-by":"publisher","DOI":"10.1021\/pr500128t"},{"key":"ref60\/cit60","doi-asserted-by":"publisher","DOI":"10.1007\/s00216-018-1418-7"},{"key":"ref61\/cit61","doi-asserted-by":"publisher","DOI":"10.1002\/prca.202300029"},{"key":"ref62\/cit62","doi-asserted-by":"publisher","DOI":"10.1002\/prca.200900150"},{"key":"ref63\/cit63","doi-asserted-by":"publisher","DOI":"10.1002\/elps.201300376"},{"key":"ref64\/cit64","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jproteome.5b01145"},{"key":"ref65\/cit65","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-019-48043-1"},{"key":"ref66\/cit66","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jproteome.1c00175"},{"key":"ref67\/cit67","doi-asserted-by":"publisher","DOI":"10.1002\/cam4.1107"},{"key":"ref68\/cit68","doi-asserted-by":"publisher","DOI":"10.1021\/pr070062p"}],"container-title":["Analytical Chemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acs.analchem.5c04479","content-type":"application\/pdf","content-version":"vor","intended-application":"unspecified"},{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acs.analchem.5c04479","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,2,10]],"date-time":"2026-02-10T09:31:23Z","timestamp":1770715883000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/acs.analchem.5c04479"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,1,29]]},"references-count":68,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2026,2,10]]}},"alternative-id":["10.1021\/acs.analchem.5c04479"],"URL":"https:\/\/doi.org\/10.1021\/acs.analchem.5c04479","relation":{},"ISSN":["0003-2700","1520-6882"],"issn-type":[{"value":"0003-2700","type":"print"},{"value":"1520-6882","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,1,29]]}}}