{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,19]],"date-time":"2026-05-19T09:07:02Z","timestamp":1779181622658,"version":"3.51.4"},"reference-count":67,"publisher":"American Chemical Society (ACS)","issue":"19","license":[{"start":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T00:00:00Z","timestamp":1777852800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T00:00:00Z","timestamp":1777852800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T00:00:00Z","timestamp":1777852800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-045"}],"funder":[{"DOI":"10.13039\/501100002979","name":"Dalian Institute of Chemical Physics, Chinese Academy of Sciences","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100002979","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100005047","name":"Natural Science Foundation of Liaoning Province","doi-asserted-by":"publisher","award":["2024-MSBA-59"],"award-info":[{"award-number":["2024-MSBA-59"]}],"id":[{"id":"10.13039\/501100005047","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100007620","name":"Department of Education of Liaoning Province","doi-asserted-by":"publisher","award":["LJ212410161028"],"award-info":[{"award-number":["LJ212410161028"]}],"id":[{"id":"10.13039\/501100007620","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100019532","name":"Science Fund for Distinguished Young Scholars of Dalian Province","doi-asserted-by":"publisher","award":["2022RJ04"],"award-info":[{"award-number":["2022RJ04"]}],"id":[{"id":"10.13039\/501100019532","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["22374148"],"award-info":[{"award-number":["22374148"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002367","name":"Chinese Academy of Sciences","doi-asserted-by":"publisher","award":["028GJHZ2023079FN"],"award-info":[{"award-number":["028GJHZ2023079FN"]}],"id":[{"id":"10.13039\/501100002367","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Liaoning Provincial Science and Technology Plan Joint Fund Project","award":["2024-MSLH-104"],"award-info":[{"award-number":["2024-MSLH-104"]}]},{"name":"Second Hospital of Dalian Medical University","award":["YJ20250007"],"award-info":[{"award-number":["YJ20250007"]}]},{"name":"Liaoning Province Science Foundation for Distinguished Young Scholars","award":["2024JH3\/50100009"],"award-info":[{"award-number":["2024JH3\/50100009"]}]},{"name":"?Xingliao Talent Plan? Medical Master Project of Liaoning Province","award":["YXMJ-QN-16"],"award-info":[{"award-number":["YXMJ-QN-16"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Anal. Chem."],"published-print":{"date-parts":[[2026,5,19]]},"DOI":"10.1021\/acs.analchem.5c08045","type":"journal-article","created":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T14:56:38Z","timestamp":1777906598000},"page":"14115-14127","source":"Crossref","is-referenced-by-count":0,"title":["Small Molecule Guided Photocatalytic Proteomics Profiling of Amyloid Deposits in Hippocampal and Cortical Alzheimer\u2019s Disease Tissues"],"prefix":"10.1021","volume":"98","author":[{"given":"Jing","family":"Yan","sequence":"first","affiliation":[{"name":"The Second Hospital of Dalian Medical University","place":["Dalian, China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Huan","family":"Feng","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Medical Proteomics, National Chromatographic R. & A. Center","place":["Dalian, China"]},{"name":"Dalian Institute of Chemical Physics, Chinese Academy of Sciences","place":["Dalian, China"]},{"name":"Institute of Natural Sciences","place":["Hangzhou, China"]},{"name":"Westlake Institute for Advanced Study","place":["Hangzhou, China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qiuxuan","family":"Xia","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Medical Proteomics, National Chromatographic R. & A. Center","place":["Dalian, China"]},{"name":"Dalian Institute of Chemical Physics, Chinese Academy of Sciences","place":["Dalian, China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Di","family":"Shen","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Medical Proteomics, National Chromatographic R. & A. Center","place":["Dalian, China"]},{"name":"Dalian Institute of Chemical Physics, Chinese Academy of Sciences","place":["Dalian, China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hao","family":"Jin","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Medical Proteomics, National Chromatographic R. & A. Center","place":["Dalian, China"]},{"name":"Dalian Institute of Chemical Physics, Chinese Academy of Sciences","place":["Dalian, China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rui","family":"Sun","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Medical Proteomics, National Chromatographic R. & A. Center","place":["Dalian, China"]},{"name":"Dalian Institute of Chemical Physics, Chinese Academy of Sciences","place":["Dalian, China"]},{"name":"University of Chinese Academy of Sciences","place":["Beijing, China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jialu","family":"Sun","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Medical Proteomics, National Chromatographic R. & A. Center","place":["Dalian, China"]},{"name":"Dalian Institute of Chemical Physics, Chinese Academy of Sciences","place":["Dalian, China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wei","family":"Tang","sequence":"additional","affiliation":[{"name":"Dalian Medical University","place":["Dalian, China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xintong","family":"Yu","sequence":"additional","affiliation":[{"name":"Dalian Medical University","place":["Dalian, China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fangliang","family":"Guo","sequence":"additional","affiliation":[{"name":"The Second Hospital of Dalian Medical University","place":["Dalian, China"]},{"name":"State Key Laboratory of Medical Proteomics, National Chromatographic R. & A. Center","place":["Dalian, China"]},{"name":"Dalian Institute of Chemical Physics, Chinese Academy of Sciences","place":["Dalian, China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hengke","family":"Guo","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Medical Proteomics, National Chromatographic R. & A. Center","place":["Dalian, China"]},{"name":"Dalian Institute of Chemical Physics, Chinese Academy of Sciences","place":["Dalian, China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yanan","family":"Huang","sequence":"additional","affiliation":[{"name":"Institute of Natural Sciences","place":["Hangzhou, China"]},{"name":"Westlake Institute for Advanced Study","place":["Hangzhou, China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yusong","family":"Ge","sequence":"additional","affiliation":[{"name":"The Second Hospital of Dalian Medical University","place":["Dalian, China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0779-1488","authenticated-orcid":true,"given":"Yu","family":"Liu","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Medical Proteomics, National Chromatographic R. & A. Center","place":["Dalian, China"]},{"name":"Dalian Institute of Chemical Physics, Chinese Academy of Sciences","place":["Dalian, China"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"316","published-online":{"date-parts":[[2026,5,4]]},"reference":[{"key":"ref1\/cit1","doi-asserted-by":"publisher","DOI":"10.1038\/nrneurol.2017.162"},{"key":"ref2\/cit2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jalz.2011.10.007"},{"key":"ref3\/cit3","doi-asserted-by":"publisher","DOI":"10.1186\/s13024-019-0333-5"},{"key":"ref4\/cit4","doi-asserted-by":"publisher","DOI":"10.1038\/s41593-020-0687-6"},{"key":"ref5\/cit5","doi-asserted-by":"publisher","DOI":"10.1038\/s41589-023-01370-x"},{"key":"ref6\/cit6","doi-asserted-by":"publisher","DOI":"10.1021\/acs.chemrev.9b00404"},{"key":"ref7\/cit7","doi-asserted-by":"publisher","DOI":"10.1038\/s41596-022-00789-1"},{"key":"ref8\/cit8","doi-asserted-by":"publisher","DOI":"10.1002\/cctc.202200077"},{"key":"ref9\/cit9","doi-asserted-by":"publisher","DOI":"10.1002\/anie.202312519"},{"key":"ref10\/cit10","doi-asserted-by":"publisher","DOI":"10.1021\/acs.analchem.4c00909"},{"key":"ref11\/cit11","doi-asserted-by":"publisher","DOI":"10.1038\/s41592-024-02507-z"},{"key":"ref12\/cit12","doi-asserted-by":"publisher","DOI":"10.1039\/C9SC04730A"},{"key":"ref13\/cit13","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejmech.2014.10.012"},{"key":"ref14\/cit14","doi-asserted-by":"publisher","DOI":"10.1002\/smll.202205634"},{"key":"ref15\/cit15","doi-asserted-by":"publisher","DOI":"10.1002\/cmdc.201900181"},{"key":"ref16\/cit16","doi-asserted-by":"publisher","DOI":"10.1002\/slct.201902281"},{"key":"ref17\/cit17","doi-asserted-by":"publisher","DOI":"10.1016\/j.immuni.2024.09.014"},{"key":"ref18\/cit18","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuron.2019.12.015"},{"key":"ref19\/cit19","doi-asserted-by":"publisher","DOI":"10.1016\/j.jalz.2018.10.006"},{"key":"ref20\/cit20","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M403672200"},{"key":"ref21\/cit21","doi-asserted-by":"publisher","DOI":"10.1007\/978-1-4939-7558-7_18"},{"key":"ref22\/cit22","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpba.2016.07.008"},{"key":"ref23\/cit23","doi-asserted-by":"publisher","DOI":"10.2165\/00007256-199520030-00004"},{"key":"ref24\/cit24","doi-asserted-by":"publisher","DOI":"10.1002\/1615-9861(200110)1:10<1200::AID-PROT1200>3.0.CO;2-Q"},{"key":"ref25\/cit25","doi-asserted-by":"publisher","DOI":"10.1038\/s41586-023-05914-y"},{"key":"ref26\/cit26","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-023-38565-8"},{"key":"ref27\/cit27","doi-asserted-by":"publisher","DOI":"10.1126\/science.adl5763"},{"key":"ref28\/cit28","doi-asserted-by":"publisher","DOI":"10.1021\/acschembio.4c00680"},{"key":"ref29\/cit29","doi-asserted-by":"publisher","DOI":"10.1016\/j.actbio.2024.12.002"},{"key":"ref30\/cit30","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-024-46985-3"},{"key":"ref31\/cit31","doi-asserted-by":"publisher","DOI":"10.1002\/anie.202303014"},{"key":"ref32\/cit32","doi-asserted-by":"publisher","DOI":"10.1039\/D2CC02263J"},{"key":"ref33\/cit33","doi-asserted-by":"publisher","DOI":"10.1021\/acscentsci.5c00520"},{"key":"ref34\/cit34","doi-asserted-by":"publisher","DOI":"10.3389\/fchbi.2023.1288188"},{"key":"ref35\/cit35","doi-asserted-by":"publisher","DOI":"10.1021\/acs.chemrev.4c00554"},{"key":"ref36\/cit36","doi-asserted-by":"publisher","DOI":"10.1002\/cbic.202200745"},{"key":"ref37\/cit37","doi-asserted-by":"publisher","DOI":"10.1111\/acel.14137"},{"key":"ref38\/cit38","doi-asserted-by":"publisher","DOI":"10.1111\/acel.14231"},{"key":"ref39\/cit39","doi-asserted-by":"publisher","DOI":"10.1006\/jsbi.2000.4221"},{"key":"ref40\/cit40","doi-asserted-by":"publisher","DOI":"10.1093\/jnen\/61.9.797"},{"key":"ref41\/cit41","doi-asserted-by":"publisher","DOI":"10.1002\/cssc.202201323"},{"key":"ref42\/cit42","doi-asserted-by":"publisher","DOI":"10.1155\/2022\/7211485"},{"key":"ref43\/cit43","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.4c00414"},{"key":"ref44\/cit44","doi-asserted-by":"publisher","DOI":"10.1002\/anie.202011108"},{"key":"ref45\/cit45","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.4c17933"},{"key":"ref46\/cit46","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-022-32689-z"},{"key":"ref47\/cit47","doi-asserted-by":"publisher","DOI":"10.1002\/anie.202108961"},{"key":"ref48\/cit48","doi-asserted-by":"publisher","DOI":"10.1038\/s41589-019-0368-5"},{"key":"ref49\/cit49","doi-asserted-by":"publisher","DOI":"10.1021\/acs.analchem.4c06453"},{"key":"ref50\/cit50","doi-asserted-by":"publisher","DOI":"10.1016\/j.cclet.2024.110127"},{"key":"ref51\/cit51","doi-asserted-by":"publisher","DOI":"10.1039\/D4CB00111G"},{"key":"ref52\/cit52","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.1836-13.2013"},{"key":"ref53\/cit53","doi-asserted-by":"publisher","DOI":"10.1038\/s41593-018-0332-9"},{"key":"ref54\/cit54","doi-asserted-by":"publisher","DOI":"10.1038\/s43587-021-00098-4"},{"key":"ref55\/cit55","doi-asserted-by":"publisher","DOI":"10.3390\/cells14120911"},{"key":"ref56\/cit56","doi-asserted-by":"publisher","DOI":"10.1038\/s41556-018-0235-8"},{"key":"ref57\/cit57","doi-asserted-by":"publisher","DOI":"10.1016\/j.nbas.2022.100056"},{"key":"ref58\/cit58","doi-asserted-by":"publisher","DOI":"10.1038\/s41580-024-00757-5"},{"key":"ref59\/cit59","doi-asserted-by":"publisher","DOI":"10.3390\/cells9061541"},{"key":"ref60\/cit60","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-022-13683-3"},{"key":"ref61\/cit61","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2202-15-73"},{"key":"ref62\/cit62","doi-asserted-by":"publisher","DOI":"10.1080\/15548627.2016.1239003"},{"key":"ref63\/cit63","doi-asserted-by":"publisher","DOI":"10.1186\/1750-1326-7-59"},{"key":"ref64\/cit64","doi-asserted-by":"publisher","DOI":"10.4103\/0366-6999.220311"},{"key":"ref65\/cit65","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0182895"},{"key":"ref66\/cit66","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-025-68017-4"},{"key":"ref67\/cit67","doi-asserted-by":"publisher","DOI":"10.1021\/acssensors.5c03211"}],"container-title":["Analytical Chemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acs.analchem.5c08045","content-type":"application\/pdf","content-version":"vor","intended-application":"unspecified"},{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acs.analchem.5c08045","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,19]],"date-time":"2026-05-19T08:11:53Z","timestamp":1779178313000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/acs.analchem.5c08045"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,5,4]]},"references-count":67,"journal-issue":{"issue":"19","published-print":{"date-parts":[[2026,5,19]]}},"alternative-id":["10.1021\/acs.analchem.5c08045"],"URL":"https:\/\/doi.org\/10.1021\/acs.analchem.5c08045","relation":{},"ISSN":["0003-2700","1520-6882"],"issn-type":[{"value":"0003-2700","type":"print"},{"value":"1520-6882","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,5,4]]}}}