{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,8]],"date-time":"2026-08-08T13:09:28Z","timestamp":1786194568582,"version":"build-2736575974"},"reference-count":57,"publisher":"American Chemical Society (ACS)","issue":"19","license":[{"start":{"date-parts":[[2026,5,6]],"date-time":"2026-05-06T00:00:00Z","timestamp":1778025600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100020581","name":"Fondazione AIRC per la ricerca sul cancro ETS","doi-asserted-by":"publisher","award":["31092"],"award-info":[{"award-number":["31092"]}],"id":[{"id":"10.13039\/100020581","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100013456","name":"Anthem Foundation","doi-asserted-by":"publisher","award":["PNC0000003"],"award-info":[{"award-number":["PNC0000003"]}],"id":[{"id":"10.13039\/100013456","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Anal. Chem."],"published-print":{"date-parts":[[2026,5,19]]},"DOI":"10.1021\/acs.analchem.6c01243","type":"journal-article","created":{"date-parts":[[2026,5,6]],"date-time":"2026-05-06T20:24:07Z","timestamp":1778099047000},"page":"14503-14515","source":"Crossref","is-referenced-by-count":2,"title":["Sequential MALDI-MSI-Based Multiomics Reveals Spatial Lipid, Glycan, and Tryptic Peptide Signatures in Breast Tumor Histopathology"],"prefix":"10.1021","volume":"98","author":[{"given":"Seyed M. J. Seyed","family":"Golestan","sequence":"first","affiliation":[{"name":"Medicinal Plants and Drug Research Institute","place":["Tehran, Iran"]},{"name":"Shahid Beheshti University","place":["Tehran, Iran"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0003-9392-8069","authenticated-orcid":true,"given":"Nicole","family":"Monza","sequence":"additional","affiliation":[{"name":"University of Milano Bicocca","place":["Vedano al Lambro, Italy"]},{"name":"Department of Medicine and Surgery, Proteomics and Metabolomics Unit","place":["Vedano al Lambro, Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Farnaz","family":"Fatahian","sequence":"additional","affiliation":[{"name":"Medicinal Plants and Drug Research Institute","place":["Tehran, Iran"]},{"name":"Shahid Beheshti University","place":["Tehran, Iran"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lisa","family":"Pagani","sequence":"additional","affiliation":[{"name":"University of Milano Bicocca","place":["Vedano al Lambro, Italy"]},{"name":"Department of Medicine and Surgery, Proteomics and Metabolomics Unit","place":["Vedano al Lambro, Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohammad Ali","family":"AS\u2018habi","sequence":"additional","affiliation":[{"name":"Medicinal Plants and Drug Research Institute","place":["Tehran, Iran"]},{"name":"Shahid Beheshti University","place":["Tehran, Iran"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6613-3936","authenticated-orcid":true,"given":"Hossein","family":"Behboudi","sequence":"additional","affiliation":[{"name":"Medicinal Plants and Drug Research Institute","place":["Tehran, Iran"]},{"name":"Shahid Beheshti University","place":["Tehran, Iran"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6530-6113","authenticated-orcid":true,"given":"Andrew","family":"Smith","sequence":"additional","affiliation":[{"name":"University of Milano Bicocca","place":["Vedano al Lambro, Italy"]},{"name":"Department of Medicine and Surgery, Proteomics and Metabolomics Unit","place":["Vedano al Lambro, Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alireza","family":"Ghassempour","sequence":"additional","affiliation":[{"name":"Medicinal Plants and Drug Research Institute","place":["Tehran, Iran"]},{"name":"Shahid Beheshti University","place":["Tehran, Iran"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6373-689X","authenticated-orcid":true,"given":"Vanna","family":"Denti","sequence":"additional","affiliation":[{"name":"University of Milano Bicocca","place":["Vedano al Lambro, Italy"]},{"name":"Department of Medicine and Surgery, Proteomics and Metabolomics Unit","place":["Vedano al Lambro, Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2026,5,6]]},"reference":[{"key":"ref1\/cit1","doi-asserted-by":"publisher","DOI":"10.1172\/JCI60534"},{"key":"ref2\/cit2","doi-asserted-by":"publisher","DOI":"10.1007\/s10549-022-06629-w"},{"key":"ref3\/cit3","doi-asserted-by":"publisher","DOI":"10.21614\/chirurgia.116.5.suppl.S105"},{"key":"ref4\/cit4","doi-asserted-by":"publisher","DOI":"10.1002\/cam4.5071"},{"key":"ref5\/cit5","doi-asserted-by":"publisher","DOI":"10.1007\/s10549-025-07729-z"},{"key":"ref6\/cit6","doi-asserted-by":"publisher","DOI":"10.5146\/tjpath.2021.01559"},{"key":"ref7\/cit7","doi-asserted-by":"publisher","DOI":"10.1007\/s10549-022-06749-3"},{"key":"ref8\/cit8","doi-asserted-by":"publisher","DOI":"10.1016\/j.jsbmb.2019.02.004"},{"key":"ref9\/cit9","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-030-15950-4_26"},{"key":"ref10\/cit10","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2020.10.036"},{"key":"ref11\/cit11","doi-asserted-by":"publisher","DOI":"10.3390\/ijms21103611"},{"key":"ref12\/cit12","doi-asserted-by":"publisher","DOI":"10.1016\/j.talanta.2020.121676"},{"key":"ref13\/cit13","doi-asserted-by":"publisher","DOI":"10.1007\/s10719-021-10001-3"},{"key":"ref14\/cit14","doi-asserted-by":"publisher","DOI":"10.1158\/0008-5472.CAN-03-3829"},{"key":"ref15\/cit15","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-020-61283-w"},{"key":"ref16\/cit16","doi-asserted-by":"publisher","DOI":"10.1016\/j.jsps.2021.04.022"},{"key":"ref17\/cit17","doi-asserted-by":"publisher","DOI":"10.3390\/ijms232012074"},{"key":"ref18\/cit18","doi-asserted-by":"publisher","DOI":"10.1158\/0008-5472.CAN-10-3894"},{"key":"ref19\/cit19","doi-asserted-by":"publisher","DOI":"10.3390\/ijms251810216"},{"key":"ref20\/cit20","doi-asserted-by":"publisher","DOI":"10.1016\/j.celrep.2019.06.046"},{"key":"ref21\/cit21","doi-asserted-by":"publisher","DOI":"10.3390\/jcm10112243"},{"key":"ref22\/cit22","doi-asserted-by":"publisher","DOI":"10.1186\/s13058-022-01513-3"},{"key":"ref23\/cit23","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-024-54145-w"},{"key":"ref24\/cit24","doi-asserted-by":"publisher","DOI":"10.1186\/s13058-025-02038-1"},{"key":"ref25\/cit25","doi-asserted-by":"publisher","DOI":"10.1101\/2023.11.04.565590"},{"key":"ref26\/cit26","doi-asserted-by":"publisher","DOI":"10.1039\/C4MB00716F"},{"key":"ref27\/cit27","doi-asserted-by":"publisher","DOI":"10.1007\/s00216-019-02296-x"},{"key":"ref28\/cit28","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jproteome.2c00601"},{"key":"ref29\/cit29","doi-asserted-by":"publisher","DOI":"10.3390\/metabo15080531"},{"key":"ref30\/cit30","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jproteome.5c00432"},{"key":"ref31\/cit31","doi-asserted-by":"publisher","DOI":"10.3390\/ijms24054410"},{"key":"ref32\/cit32","doi-asserted-by":"publisher","DOI":"10.3390\/ijms241411756"},{"key":"ref33\/cit33","doi-asserted-by":"publisher","DOI":"10.1007\/s10875-024-01793-8"},{"key":"ref34\/cit34","doi-asserted-by":"publisher","DOI":"10.1038\/nmeth.4072"},{"key":"ref35\/cit35","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0283155"},{"key":"ref36\/cit36","doi-asserted-by":"publisher","DOI":"10.3390\/cancers13174349"},{"key":"ref37\/cit37","doi-asserted-by":"publisher","DOI":"10.1038\/onc.2013.408"},{"key":"ref38\/cit38","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2407-11-465"},{"key":"ref39\/cit39","doi-asserted-by":"publisher","DOI":"10.18565\/aig.2017.4.119-25"},{"key":"ref40\/cit40","doi-asserted-by":"publisher","DOI":"10.1016\/j.jss.2016.05.022"},{"key":"ref41\/cit41","doi-asserted-by":"publisher","DOI":"10.3390\/ijms21124568"},{"key":"ref42\/cit42","doi-asserted-by":"publisher","DOI":"10.1074\/mcp.m110.002717"},{"key":"ref43\/cit43","doi-asserted-by":"publisher","DOI":"10.3892\/ol.2017.7384"},{"key":"ref44\/cit44","doi-asserted-by":"publisher","DOI":"10.1172\/jci.insight.146945"},{"key":"ref45\/cit45","doi-asserted-by":"publisher","DOI":"10.3390\/cancers14061552"},{"key":"ref46\/cit46","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijms.2018.01.002"},{"key":"ref47\/cit47","doi-asserted-by":"publisher","DOI":"10.1002\/1878-0261.12312"},{"key":"ref48\/cit48","doi-asserted-by":"publisher","DOI":"10.1016\/j.breast.2017.06.005"},{"key":"ref49\/cit49","doi-asserted-by":"publisher","DOI":"10.1002\/cyto.990120107"},{"key":"ref50\/cit50","doi-asserted-by":"publisher","DOI":"10.1007\/s00018-010-0595-0"},{"key":"ref51\/cit51","doi-asserted-by":"publisher","DOI":"10.1038\/nrc3982"},{"key":"ref52\/cit52","doi-asserted-by":"publisher","DOI":"10.15252\/msb.20178124"},{"key":"ref53\/cit53","doi-asserted-by":"publisher","DOI":"10.1186\/s13059-020-02015-1"},{"key":"ref54\/cit54","doi-asserted-by":"publisher","DOI":"10.1093\/bioinformatics\/bty1054"},{"key":"ref55\/cit55","doi-asserted-by":"publisher","DOI":"10.1021\/pr500253j"},{"key":"ref56\/cit56","doi-asserted-by":"publisher","DOI":"10.1038\/srep21043"},{"key":"ref57\/cit57","doi-asserted-by":"publisher","DOI":"10.1002\/prca.201700152"}],"container-title":["Analytical Chemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acs.analchem.6c01243","content-type":"application\/pdf","content-version":"vor","intended-application":"unspecified"},{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acs.analchem.6c01243","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,19]],"date-time":"2026-05-19T08:11:29Z","timestamp":1779178289000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/acs.analchem.6c01243"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,5,6]]},"references-count":57,"journal-issue":{"issue":"19","published-print":{"date-parts":[[2026,5,19]]}},"alternative-id":["10.1021\/acs.analchem.6c01243"],"URL":"https:\/\/doi.org\/10.1021\/acs.analchem.6c01243","relation":{},"ISSN":["0003-2700","1520-6882"],"issn-type":[{"value":"0003-2700","type":"print"},{"value":"1520-6882","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,5,6]]}}}