{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,29]],"date-time":"2026-10-29T20:19:06Z","timestamp":1793305146175,"version":"4.5.0"},"reference-count":49,"publisher":"American Chemical Society (ACS)","issue":"32","license":[{"start":{"date-parts":[[2026,8,4]],"date-time":"2026-08-04T00:00:00Z","timestamp":1785801600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,8,4]],"date-time":"2026-08-04T00:00:00Z","timestamp":1785801600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,8,4]],"date-time":"2026-08-04T00:00:00Z","timestamp":1785801600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-045"}],"funder":[{"name":"Key Project of Science and Technology Plan of Beijing Education Commission","award":["KZ20231002807"],"award-info":[{"award-number":["KZ20231002807"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,8,18]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Most studies focus on improving the activity of nanozymes to build a nanozyme-based \u201cchemical tongue\u201d for the sensitive discrimination of multiple analytes. However, the construction of sensing units with multidimensional signals is often overlooked, which greatly limits the ultrasensitive identification of antibiotics and even their subtypes. Herein, we have for the first time designed the high performance of a \u201cchemical tongue\u201d by integrating high peroxidase (POD)-like activity Prussian blue analogues (PBAs) with multidimensional information from multiple oxidation products of 3,3\u2032,5,5\u2032-tetramethylbenzidine (TMB) as sensing units. Initially, the bimetallic PBA with boosted POD-like activity is achieved via combining FeRu metal doping with an acid-etching morphological reconstruction strategy. More importantly, the catalytic activity for this hollow-structure nanozyme with a specific activity of 73.3 U\/mg is increased by approximately 10 times compared to the pristine Prussian blue (PB) through the synergistic reconstruction of redox couples and exposure of more active sites. And then, the one-electron, one\/two-electron, and two-electron oxidation products of TMB are achieved by rationally controlling the concentration of the nanozyme, yielding three chromogenic products as three sensing units with six-wavelength channels. Therefore, the developed array is successfully applied to the ultrasensitive detection of seven antibiotics with down to 0.1 \u03bcM and even the discrimination of three subtypes including aminoglycosides, penicillins, and tetracyclines. The sensing mechanism depends on the variable inhibition efficiency of multiple antibiotics on the nanozyme catalytic activity. Furthermore, it enables identification of molar ratios in binary mixtures and also exhibits quantitative analysis of individual antibiotics over a broad concentration range from 0.1 to 200 \u03bcM. Moreover, with the assistance of optimizing various machine learning, the concentration-independent recognition model is built against this array, which enormously improves the discrimination accuracy of seven antibiotics from 73.03% by Decision Tree (DT) to 96.63% by the Gaussian Process Classification (GPC) algorithm. The outstanding discrimination capability of this array enables accurate identification of seven antibiotics in three real food samples (honey, milk, and chicken breast). This study provides a new perspective for configuring high-feature sensor arrays in the application of food and environmental samples.<\/jats:p>","DOI":"10.1021\/acs.analchem.6c02885","type":"journal-article","created":{"date-parts":[[2026,8,5]],"date-time":"2026-08-05T13:02:28Z","timestamp":1785934948000},"page":"23736-23749","source":"Crossref","is-referenced-by-count":2,"title":["An Ultrasensitive Multiplexing Approach via Integrating\nBoosted Nanozyme Activity with Multidimensional Information for Antibiotic\nRecognition"],"prefix":"10.1021","volume":"98","author":[{"given":"Nan","family":"Wang","sequence":"first","affiliation":[{"name":"Capital Normal University , , ,","place":["Beijing, China, 100048"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaoyan","family":"Su","sequence":"additional","affiliation":[{"name":"Capital Normal University , , ,","place":["Beijing, China, 100048"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuan","family":"Nie","sequence":"additional","affiliation":[{"name":"Capital Normal University , , ,","place":["Beijing, China, 100048"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Huashuo","family":"Dou","sequence":"additional","affiliation":[{"name":"Capital Normal University , , ,","place":["Beijing, China, 100048"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiaxi","family":"Wang","sequence":"additional","affiliation":[{"name":"Capital Normal University , , ,","place":["Beijing, China, 100048"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Minglang","family":"Rui","sequence":"additional","affiliation":[{"name":"Capital Normal University , , ,","place":["Beijing, China, 100048"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5335-3334","authenticated-orcid":true,"given":"Yueying","family":"Liu","sequence":"additional","affiliation":[{"name":"Capital Normal University , , ,","place":["Beijing, China, 100048"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2026,8,4]]},"reference":[{"key":"2026081809071831900_cit1","doi-asserted-by":"publisher","first-page":"142349","DOI":"10.1016\/j.foodchem.2024.142349","article-title":"pH-regulated CQDs@Eu\/GMP ICP sensor\narray and its fingerprinting on 96-well plates: toward point-of-use\/specific\nidentification and quantitation of six tetracyclines in animal farm\nwastewater, milks and milk-derivative products","volume":"468","author":"Gao","year":"2025","journal-title":"Food Chem."},{"key":"2026081809071831900_cit2","doi-asserted-by":"publisher","first-page":"143722","DOI":"10.1016\/j.foodchem.2025.143722","article-title":"Machine learning-assisted\nratiometric fluorescence sensor array for\nrecognition of multiple quinolones antibiotics","volume":"478","author":"Li","year":"2025","journal-title":"Food Chem."},{"key":"2026081809071831900_cit3","doi-asserted-by":"publisher","first-page":"128311","DOI":"10.1016\/j.talanta.2025.128311","article-title":"A novel sensor array\ncombined with machine learning for the effective\ndifferentiation of multiple classes of antibiotics based on copper-based\nnanozymes with laccase-like activity","volume":"295","author":"Zhen","year":"2025","journal-title":"Talanta"},{"key":"2026081809071831900_cit4","doi-asserted-by":"publisher","first-page":"18299","DOI":"10.1021\/acs.analchem.5c03414","article-title":"Single-component dual-emissive\nMOF\nsensor array for fingerprint identification of multiplex antibiotics","volume":"97","author":"Chi","year":"2025","journal-title":"Anal. Chem."},{"key":"2026081809071831900_cit5","doi-asserted-by":"publisher","first-page":"12550","DOI":"10.1021\/acs.analchem.3c02911","article-title":"Enhancement of the\nperoxidase activity of g-C3N4 with different\nmorphologies for simultaneous detection\nof multiple antibiotics","volume":"95","author":"Che","year":"2023","journal-title":"Anal. Chem."},{"key":"2026081809071831900_cit6","doi-asserted-by":"publisher","first-page":"18742","DOI":"10.1021\/acs.analchem.5c03462","article-title":"Smartphone-integrated\nfluorescent sensing array assembled from lanthanide metal-organic\nframeworks for rapid identification and differentiation of antibiotics\nin daily foods","volume":"97","author":"Zhang","year":"2025","journal-title":"Anal. Chem."},{"key":"2026081809071831900_cit7","doi-asserted-by":"publisher","first-page":"167711","DOI":"10.1016\/j.cej.2025.167711","article-title":"A three-channel nanozyme sensor array\ncombined with machine learning\nalgorithm for the differentiation and detection of aminoglycoside\nantibiotics","volume":"522","author":"Zhen","year":"2025","journal-title":"Chem. Eng. J."},{"key":"2026081809071831900_cit8","doi-asserted-by":"publisher","first-page":"15969","DOI":"10.1021\/acs.analchem.5c02680","article-title":"Automatic\nimage processing-assisted ratiometric afterglow sensor\narray for the discrimination and detection of fluoroquinolones enabled\nby a universal host-guest strategy","volume":"97","author":"Chen","year":"2025","journal-title":"Anal. Chem."},{"key":"2026081809071831900_cit9","doi-asserted-by":"publisher","first-page":"117831","DOI":"10.1016\/j.trac.2024.117831","article-title":"Recent developments\nin sample pretreatment techniques\nfor the determination of fluoroquinolones in foods","volume":"178","author":"Timofeeva","year":"2024","journal-title":"TrAC-Trend. Anal. Chem."},{"key":"2026081809071831900_cit10","doi-asserted-by":"publisher","first-page":"468","DOI":"10.1002\/jrs.6509","article-title":"Rapid detection\nand whole class control of quinolone antibiotics in pork based on\nsurface-enhanced Raman spectroscopy","volume":"54","author":"Zheng","year":"2023","journal-title":"J. Raman\nSpectrosc."},{"key":"2026081809071831900_cit11","doi-asserted-by":"publisher","first-page":"116726","DOI":"10.1016\/j.trac.2022.116726","article-title":"Current advances\nin immunoassays for quinolones in\nfood and environmental samples","volume":"157","author":"Pan","year":"2022","journal-title":"TrAC-Trend.\nAnal. Chem."},{"key":"2026081809071831900_cit12","doi-asserted-by":"publisher","first-page":"1353","DOI":"10.1016\/j.cclet.2021.08.095","article-title":"A new Eu-MOF for ratiometrically\nfluorescent detection toward quinolone antibiotics and selective detection\ntoward tetracycline antibiotics","volume":"33","author":"Wang","year":"2022","journal-title":"Chin. Chem.\nLett."},{"key":"2026081809071831900_cit13","doi-asserted-by":"publisher","first-page":"130074","DOI":"10.1016\/j.foodchem.2021.130074","article-title":"Microbiological\ninhibition-based method for screening and identifying of antibiotic\nresidues in milk, chicken egg and honey","volume":"363","author":"Wu","year":"2021","journal-title":"Food\nChem."},{"key":"2026081809071831900_cit14","doi-asserted-by":"publisher","first-page":"127524","DOI":"10.1016\/j.talanta.2025.127524","article-title":"Prospects for the\nuse of nanozyme-based electrochemical\nand colorimetric sensors for antibiotic detection","volume":"286","author":"Guliy","year":"2025","journal-title":"Talanta"},{"key":"2026081809071831900_cit15","doi-asserted-by":"publisher","first-page":"130560","DOI":"10.1016\/j.foodchem.2021.130560","article-title":"G-quadruplex DNAzyme\nas peroxidase mimetic in a colorimetric biosensor\nfor ultrasensitive and selective detection of trace tetracyclines\nin foods","volume":"366","author":"Tang","year":"2022","journal-title":"Food Chem."},{"key":"2026081809071831900_cit16","doi-asserted-by":"publisher","first-page":"122894","DOI":"10.1016\/j.jhazmat.2020.122894","article-title":"A dual-response\nratiometric fluorescent\nsensor by europium-doped CdTe quantum dots for visual and colorimetric\ndetection of tetracycline","volume":"398","author":"Han","year":"2020","journal-title":"J. Hazard. Mater."},{"key":"2026081809071831900_cit17","doi-asserted-by":"publisher","first-page":"1021","DOI":"10.1039\/C7NJ03124F","article-title":"Construction of a sensitive non-enzymatic\nfructose\ncarbon paste electrode-CuO nanoflower: designing the experiments by\nresponse surface methodology","volume":"42","author":"Amani-Beni","year":"2018","journal-title":"New J. Chem."},{"key":"2026081809071831900_cit18","doi-asserted-by":"publisher","first-page":"186","DOI":"10.1016\/j.jcis.2017.05.049","article-title":"A novel non-enzymatic glucose sensor based on the modification\nof carbon paste electrode with CuO nanoflower: designing the experiments\nby response surface methodology (RSM)","volume":"504","author":"Amani-Beni","year":"2017","journal-title":"J. Colloid\nInterface Sci."},{"key":"2026081809071831900_cit19","doi-asserted-by":"publisher","first-page":"1747","DOI":"10.1021\/acs.analchem.5c06795","article-title":"Gold nanocluster-based sensor array\nwith PCA-assisted pattern recognition for discriminating multiple\nantibiotics in different complex biological samples","volume":"98","author":"Liu","year":"2026","journal-title":"Anal. Chem."},{"key":"2026081809071831900_cit20","doi-asserted-by":"publisher","first-page":"115754","DOI":"10.1016\/j.trac.2019.115754","article-title":"Colorimetric sensor\narray based on gold nanoparticles:\ndesign principles and recent advances","volume":"122","author":"Sun","year":"2020","journal-title":"TrAC-Trend.\nAnal. Chem."},{"key":"2026081809071831900_cit21","doi-asserted-by":"publisher","first-page":"3354","DOI":"10.1021\/ac504587h","article-title":"Multidimensional\nsensor for pattern recognition of\nproteins based on DNA-gold nanoparticles conjugates","volume":"87","author":"Sun","year":"2015","journal-title":"Anal. Chem."},{"key":"2026081809071831900_cit22","doi-asserted-by":"publisher","first-page":"9983","DOI":"10.1021\/acs.analchem.8b02428","article-title":"2D-metal-organic-framework-nanozyme\nsensor arrays for probing phosphates and their enzymatic hydrolysis","volume":"90","author":"Qin","year":"2018","journal-title":"Anal. Chem."},{"key":"2026081809071831900_cit23","doi-asserted-by":"publisher","first-page":"8221","DOI":"10.1021\/acs.analchem.4c00670","article-title":"Construction\nand application of nanozyme sensor arrays","volume":"96","author":"Xia","year":"2024","journal-title":"Anal.\nChem."},{"key":"2026081809071831900_cit24","doi-asserted-by":"publisher","DOI":"10.1002\/adfm.202519764","article-title":"Dual-axial chlorine\ncoordination engineering of Fe-Fe dual single atoms boosts the ascorbate\noxidase-like activity","volume":"36","author":"Guo","year":"2025","journal-title":"Adv. Funct. Mater."},{"key":"2026081809071831900_cit25","doi-asserted-by":"publisher","first-page":"9107","DOI":"10.1021\/acs.analchem.3c01594","article-title":"Visual sensor\narrays for distinction of phenolic acids based on two single-atom\nnanozymes","volume":"95","author":"Huang","year":"2023","journal-title":"Anal. Chem."},{"key":"2026081809071831900_cit26","doi-asserted-by":"publisher","first-page":"17552","DOI":"10.1021\/acs.analchem.5c02558","article-title":"Machine learning-enhanced\nnanozyme sensor array for accurate multiple quinolone antibiotics\nrecognition","volume":"97","author":"Shi","year":"2025","journal-title":"Anal. Chem."},{"key":"2026081809071831900_cit27","doi-asserted-by":"publisher","first-page":"172753","DOI":"10.1016\/j.cej.2026.172753","article-title":"Histidine-engineered\nCu-HAc nanozyme with boosted peroxidase-like activity for accurate\nintelligent identification of \u03b2-lactam antibiotics through machine\nlearning","volume":"529","author":"Xu","year":"2026","journal-title":"Chem. Eng. J."},{"key":"2026081809071831900_cit28","doi-asserted-by":"publisher","first-page":"157234","DOI":"10.1016\/j.cej.2024.157234","article-title":"A colorimetric sensor\narray based on bimetallic CeCo-MOF with triple-enzyme-mimic\nactivities for highly sensitive detection of tetracycline antibiotics","volume":"500","author":"Ran","year":"2024","journal-title":"Chem. Eng. J."},{"key":"2026081809071831900_cit29","doi-asserted-by":"publisher","DOI":"10.1002\/adma.202209633","article-title":"Effect of phosphorus\nmodulation in iron single-atom\ncatalysts for peroxidase mimicking","volume":"36","author":"Ding","year":"2024","journal-title":"Adv. Mater."},{"key":"2026081809071831900_cit30","doi-asserted-by":"publisher","first-page":"2928","DOI":"10.1007\/s12598-023-02309-w","article-title":"Metal nanozymes\nwith multiple catalytic activities: regulating strategies and biological\napplications","volume":"42","author":"Yang","year":"2023","journal-title":"Rare Metals"},{"key":"2026081809071831900_cit31","doi-asserted-by":"publisher","first-page":"15","DOI":"10.1016\/j.actbio.2021.02.036","article-title":"Chemical design of nanozymes for biomedical applications","volume":"126","author":"Wei","year":"2021","journal-title":"Acta Biomater."},{"key":"2026081809071831900_cit32","doi-asserted-by":"publisher","first-page":"6060","DOI":"10.1039\/c3cs35486e","article-title":"Nanomaterials with\nenzyme-like characteristics (nanozymes): next-generation\nartificial enzymes","volume":"42","author":"Wei","year":"2013","journal-title":"Chem. Soc. Rev."},{"key":"2026081809071831900_cit33","doi-asserted-by":"publisher","first-page":"1004","DOI":"10.1039\/C8CS00457A","article-title":"Nanomaterials with\nenzyme-like characteristics (nanozymes): next-generation artificial\nenzymes (II)","volume":"48","author":"Wu","year":"2019","journal-title":"Chem. Soc. Rev."},{"key":"2026081809071831900_cit34","doi-asserted-by":"publisher","first-page":"15338","DOI":"10.1021\/acs.analchem.4c02995","article-title":"Structure remodeling strategy for\nopen-cage NiFe@Fe-bis-PBA with enhanced peroxidase-like activity to\nmonitor tumor markers","volume":"96","author":"Liu","year":"2024","journal-title":"Anal. Chem."},{"key":"2026081809071831900_cit35","doi-asserted-by":"publisher","first-page":"11697","DOI":"10.1021\/acs.nanolett.4c03314","article-title":"Ultrasmall\nprussian blue nanozyme\nattenuates osteoarthritis by scavenging reactive oxygen species and\nregulating macrophage phenotype","volume":"24","author":"Qin","year":"2024","journal-title":"Nano Lett."},{"key":"2026081809071831900_cit36","doi-asserted-by":"publisher","first-page":"138766","DOI":"10.1016\/j.ijbiomac.2024.138766","article-title":"Etched\nCoFe prussian blue analog nanozymes with superior peroxidase activity\nfor colorimetric biosensing of hydrogen peroxide and dopamine","volume":"288","author":"Ramgopal","year":"2025","journal-title":"Int. J. Biol. Macromol."},{"key":"2026081809071831900_cit37","doi-asserted-by":"publisher","first-page":"4382","DOI":"10.1021\/acs.analchem.5c08080","article-title":"DNA-encoded bimetallic\nPtAg nanocluster-zyme with programmable POD-mimicking\nactivity for accurate trimodal biosensing and cascade logic circuit-empowered\ntarget recognition","volume":"98","author":"Wang","year":"2026","journal-title":"Anal. Chem."},{"key":"2026081809071831900_cit38","doi-asserted-by":"publisher","first-page":"2401607","DOI":"10.1002\/adhm.202401607","article-title":"Mitochondria-targeting\nbimetallic cluster nanozymes alleviate neuropathic pain through scavenging\nROS and reducing inflammation","volume":"14","author":"Cheng","year":"2025","journal-title":"Adv. Healthc.\nMater."},{"key":"2026081809071831900_cit39","doi-asserted-by":"publisher","DOI":"10.1002\/adma.202409840","article-title":"Engineering mild-photothermal\nresponsive\nand NO donor prussian blue nanozymes using mild synthesis for inflammation\nregulation and bacterial eradication in periodontal disease","volume":"37","author":"Li","year":"2025","journal-title":"Adv. Mater."},{"key":"2026081809071831900_cit40","doi-asserted-by":"publisher","DOI":"10.1002\/advs.202515765","article-title":"DFT-guided design of a multi-enzyme mimetic high-entropy nanozyme\nfor cascaded glutathione detection and point-of-care testing","volume":"13","author":"Lin","year":"2026","journal-title":"Adv. Sci."},{"key":"2026081809071831900_cit41","doi-asserted-by":"publisher","DOI":"10.1002\/ange.202414650","article-title":"Spiral-concave prussian\nblue crystals with rich steps: growth mechanism and coordination regulation","volume":"137","author":"Zhang","year":"2025","journal-title":"Angew. Chem."},{"key":"2026081809071831900_cit42","doi-asserted-by":"publisher","first-page":"585","DOI":"10.1021\/accountsmr.3c00289","article-title":"Prussian blue\nanalogues and their derivatives: from elaborate microstructure design\nto boosted fenton-like application","volume":"5","author":"Zhang","year":"2024","journal-title":"Acc. Mater.\nRes."},{"key":"2026081809071831900_cit43","doi-asserted-by":"publisher","first-page":"161080","DOI":"10.1016\/j.cej.2025.161080","article-title":"Hollow FeNi prussian\nblue nanocages with enhanced peroxidase-mimicking activity for colorimetric\ndetection of mercury ions and L-cysteine","volume":"508","author":"Lu","year":"2025","journal-title":"Chem.\nEng. J."},{"key":"2026081809071831900_cit44","doi-asserted-by":"publisher","first-page":"164583","DOI":"10.1016\/j.cej.2025.164583","article-title":"Precursor ratio-modulated\nenzyme-mimicking ZIF-67 nanoflower array: a colorimetric \u2033electronic\ntongue\u2033 for antioxidant monitoring","volume":"518","author":"Yu","year":"2025","journal-title":"Chem.\nEng. J."},{"key":"2026081809071831900_cit45","doi-asserted-by":"publisher","first-page":"139326","DOI":"10.1016\/j.foodchem.2024.139326","article-title":"Nanozymes\nsensor array for discrimination\nand intelligent sensing of phenolic acids in food","volume":"450","author":"Jing","year":"2024","journal-title":"Food Chem."},{"key":"2026081809071831900_cit46","doi-asserted-by":"publisher","first-page":"10842","DOI":"10.1039\/D5SC01799H","article-title":"Multi-site\norbital\ncoupling in Ru-based high-entropy alloy-enabled hydroxyl spillover\nfor enhanced peroxidase-like activity","volume":"16","author":"Yang","year":"2025","journal-title":"Chem.\nSci."},{"key":"2026081809071831900_cit47","doi-asserted-by":"publisher","first-page":"1506","DOI":"10.1038\/s41596-018-0001-1","article-title":"Standardized assays for determining\nthe catalytic activity and kinetics of peroxidase-like nanozymes","volume":"13","author":"Jiang","year":"2018","journal-title":"Nat. Commun."},{"key":"2026081809071831900_cit48","doi-asserted-by":"publisher","first-page":"5189","DOI":"10.1021\/acsnano.0c10388","article-title":"Platinum-doped prussian\nblue nanozymes for multiwavelength bioimaging guided photothermal\ntherapy of tumor and anti-inflammation","volume":"15","author":"Li","year":"2021","journal-title":"ACS\nNano"},{"key":"2026081809071831900_cit49","doi-asserted-by":"publisher","first-page":"160553","DOI":"10.1016\/j.cej.2025.160553","article-title":"Ru nanoclusters engineer prussian blue analog nanocubes\nfor multiple active sites synergistic catalysis enabling high-performance\nbacterial detection","volume":"507","author":"Ma","year":"2025","journal-title":"Chem. Eng. J."}],"container-title":["Analytical Chemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acs.analchem.6c02885","content-type":"application\/pdf","content-version":"vor","intended-application":"unspecified"},{"URL":"https:\/\/pubs.acs.org\/ancham\/article-pdf\/98\/32\/23736\/66378741\/acs.analchem.6c02885.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/pubs.acs.org\/ancham\/article-pdf\/98\/32\/23736\/66378741\/acs.analchem.6c02885.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T15:57:04Z","timestamp":1787068624000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/ancham\/article\/98\/32\/23736\/5242158\/An-Ultrasensitive-Multiplexing-Approach-via"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,8,4]]},"references-count":49,"journal-issue":{"issue":"32","published-online":{"date-parts":[[2026,8,4]]},"published-print":{"date-parts":[[2026,8,18]]}},"URL":"https:\/\/doi.org\/10.1021\/acs.analchem.6c02885","relation":{},"ISSN":["0003-2700","1520-6882"],"issn-type":[{"value":"0003-2700","type":"print"},{"value":"1520-6882","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,8,4]]}}}