{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,15]],"date-time":"2026-09-15T16:16:17Z","timestamp":1789488977765,"version":"build-2803163510"},"reference-count":52,"publisher":"American Chemical Society (ACS)","issue":"36","license":[{"start":{"date-parts":[[2026,9,2]],"date-time":"2026-09-02T00:00:00Z","timestamp":1788307200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,9,2]],"date-time":"2026-09-02T00:00:00Z","timestamp":1788307200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,9,2]],"date-time":"2026-09-02T00:00:00Z","timestamp":1788307200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-045"}],"funder":[{"DOI":"10.13039\/501100001700","name":"Ministry of Education, Culture, Sports, Science and Technology","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001700","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100009023","name":"Precursory Research for Embryonic Science and Technology","doi-asserted-by":"publisher","award":["JPMJPR20B8"],"award-info":[{"award-number":["JPMJPR20B8"]}],"id":[{"id":"10.13039\/501100009023","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,9,15]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>In regenerative medicine, cell therapy often relies on suspension cells, creating an urgent need for efficient delivery of multiple cargoes into these cells. Our previous nanotube (NT) stamping platform enabled efficient delivery into adherent cells, but delivery into suspension cells\u2500a major therapeutic target\u2500has not yet been realized. Here, we present a versatile NT stamping platform enabling high-efficiency, size-independent delivery into suspension cells without compromising viability. Our platform consists of a vertically aligned gold NT array integrated onto a glass stamp, allowing controlled interfaces with cells under microscopic observation. By optimizing NT geometry and insertion depth, we achieved efficient intracellular delivery of fluorescent dyes, proteins (GFP and LOx), and mitochondria into suspension cells immobilized by a temporary Cell-Tak adhesion strategy, with delivery efficiencies exceeding 90% and cell viability above 85%, respectively. Unlike electroporation, our approach maintains cellular functionality and enables precise, reagent-free delivery. Notably, the platform\u2019s ability to reversibly extract and inject intracellular fluid enabled the direct transfer of stem cell\u2013derived mitochondria into suspension cells, enhancing ATP production per cell by 2-fold for at least 1 week. These results establish NT stamping as a complementary intracellular delivery platform for applications requiring precise delivery of cargoes spanning from small molecules to intact organelles while maintaining high cell viability.<\/jats:p>","DOI":"10.1021\/acs.analchem.6c03151","type":"journal-article","created":{"date-parts":[[2026,9,3]],"date-time":"2026-09-03T16:20:56Z","timestamp":1788452456000},"page":"26680-26689","source":"Crossref","is-referenced-by-count":0,"title":["A Bidirectional\nNanotube Stamping Platform for Organelle-Scale\nIntracellular Delivery into Suspension Cells"],"prefix":"10.1021","volume":"98","author":[{"ORCID":"https:\/\/orcid.org\/0009-0009-3370-7655","authenticated-orcid":true,"given":"Kazuhiro","family":"Oyama","sequence":"first","affiliation":[{"name":"Waseda University , , 2-7 Hibikino , Wakamatsu-ku, , ,","place":["Kitakyushu-shi, Fukuoka-ken, Japan, 808-0135"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mizuha","family":"Takaoka","sequence":"additional","affiliation":[{"name":"Hynts Tech Corporation , 1-8 Hibikino , Wakamatsu-ku, , ,","place":["Kitakyushu-shi, Fukuoka-ken, Japan, 808-0135"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bingfu","family":"Liu","sequence":"additional","affiliation":[{"name":"Waseda University , , 2-7 Hibikino , Wakamatsu-ku, , ,","place":["Kitakyushu-shi, Fukuoka-ken, Japan, 808-0135"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2325-5084","authenticated-orcid":true,"given":"Tsutomu","family":"Mikawa","sequence":"additional","affiliation":[{"name":"RIKEN Center for Integrative Medical Science , 1-7-22 Suehiro-cho , Tsurumi-ku, , ,","place":["Yokohama-shi, Kanagawa-ken, Japan, 230-0045"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mutsuko","family":"Aoki","sequence":"additional","affiliation":[{"name":"Hynts Tech Corporation , 1-8 Hibikino , Wakamatsu-ku, , ,","place":["Kitakyushu-shi, Fukuoka-ken, Japan, 808-0135"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4859-1359","authenticated-orcid":true,"given":"Ga\u0301bor","family":"Me\u0301hes","sequence":"additional","affiliation":[{"name":"Waseda University , , 2-7 Hibikino , Wakamatsu-ku, , ,","place":["Kitakyushu-shi, Fukuoka-ken, Japan, 808-0135"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7445-633X","authenticated-orcid":true,"given":"Takeo","family":"Miyake","sequence":"additional","affiliation":[{"name":"Waseda University , , 2-7 Hibikino , Wakamatsu-ku, , ,","place":["Kitakyushu-shi, Fukuoka-ken, Japan, 808-0135"]},{"name":"Hynts Tech Corporation , 1-8 Hibikino , Wakamatsu-ku, , ,","place":["Kitakyushu-shi, Fukuoka-ken, Japan, 808-0135"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2026,9,2]]},"reference":[{"issue":"10","key":"2026091511065474300_cit1","doi-asserted-by":"publisher","first-page":"819","DOI":"10.1038\/s41565-020-0759-5","article-title":"A Framework\nfor Designing Delivery Systems","volume":"15","author":"Poon","year":"2020","journal-title":"Nat. Nanotechnol."},{"issue":"18","key":"2026091511065474300_cit2","doi-asserted-by":"publisher","first-page":"22958","DOI":"10.1021\/acsami.4c03013","article-title":"Chemical Plasma\nMembrane Perforation Generated by a\nMicrofluidic Probe for Single-Cell Intracellular Protein Delivery","volume":"16","author":"Song","year":"2024","journal-title":"ACS Appl. Mater. Interfaces"},{"issue":"7624","key":"2026091511065474300_cit3","doi-asserted-by":"publisher","first-page":"183","DOI":"10.1038\/nature19764","article-title":"In Vitro and Ex\nVivo Strategies for Intracellular Delivery","volume":"538","author":"Stewart","year":"2016","journal-title":"Nature"},{"issue":"22","key":"2026091511065474300_cit4","doi-asserted-by":"publisher","first-page":"4487","DOI":"10.1002\/smll.201401532","article-title":"Micro- and Nanotechnologies\nfor Intracellular Delivery","volume":"10","author":"Yan","year":"2014","journal-title":"Small"},{"issue":"12","key":"2026091511065474300_cit5","doi-asserted-by":"publisher","first-page":"125002","DOI":"10.1088\/1361-6439\/ac984a","article-title":"Micromechanical Valve-Operated Needle-on-a-Chip Microinjection\nModule for Microfluidic Large-Scale Integration","volume":"32","author":"Gray-Scherr","year":"2022","journal-title":"J. Micromech. Microeng."},{"issue":"8","key":"2026091511065474300_cit6","doi-asserted-by":"publisher","first-page":"686","DOI":"10.1016\/j.tibtech.2017.03.015","article-title":"How Does\nMembrane Oxidation Affect Cell Delivery and Cell Killing","volume":"35","author":"Libardo","year":"2017","journal-title":"Trends Biotechnol."},{"issue":"12","key":"2026091511065474300_cit7","doi-asserted-by":"publisher","first-page":"3127","DOI":"10.1088\/0957-0233\/17\/12\/S02","article-title":"Electroporation through\na Micro-Fabricated Orifice\nand Its Application to the Measurement of Cell Response to External\nStimuli","volume":"17","author":"Kurosawa","year":"2006","journal-title":"Meas. Sci. Technol."},{"issue":"7","key":"2026091511065474300_cit8","doi-asserted-by":"publisher","first-page":"841","DOI":"10.1002\/j.1460-2075.1982.tb01257.x","article-title":"Gene Transfer\ninto Mouse Lyoma Cells by Electroporation in High Electric Fields","volume":"1","author":"Neumann","year":"1982","journal-title":"EMBO J."},{"issue":"6","key":"2026091511065474300_cit9","doi-asserted-by":"publisher","first-page":"750","DOI":"10.1023\/A:1012198321879","article-title":"The Use of\nSonication for the Efficient\nDelivery of Plasmid DNA into Cells","volume":"14","author":"Wyber","year":"1997","journal-title":"Pharm. Res."},{"key":"2026091511065474300_cit10","doi-asserted-by":"publisher","first-page":"139","DOI":"10.1007\/978-981-99-6564-9_6","article-title":"Thermoporation Based Drug Delivery Systems","volume-title":"Advanced Drug Delivery; Methods and Applications","author":"Rohit","year":"2023"},{"key":"2026091511065474300_cit11","doi-asserted-by":"publisher","first-page":"9880","DOI":"10.1016\/j.apsusc.2009.04.111","article-title":"Gene delivery process\nin a single animal cell after\nfemtosecond laser microinjection","volume":"255","author":"Hosokawa","year":"2009","journal-title":"Appl. Surf.\nSci."},{"key":"2026091511065474300_cit12","doi-asserted-by":"publisher","first-page":"5417","DOI":"10.1038\/srep05417","article-title":"Microinjection-Free\nDelivery of miRNA Inhibitor into Zygotes","volume":"4","author":"Joo","year":"2014","journal-title":"Sci.\nRep."},{"issue":"2","key":"2026091511065474300_cit13","doi-asserted-by":"publisher","first-page":"378","DOI":"10.1016\/j.ijpharm.2011.12.030","article-title":"Novel Hyperbranched\nPolyamidoamine Nanoparticle-Based Gene Delivery: Transfection, Cytotoxicity,\nand in Vitro Evaluation","volume":"423","author":"Zhu","year":"2012","journal-title":"Int. J. Pharm."},{"issue":"1","key":"2026091511065474300_cit14","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1089\/oli.2010.0264","article-title":"Cell-Specific Aptamer-Mediated Targeted Drug Delivery","volume":"21","author":"Zhou","year":"2011","journal-title":"Oligonucleotides"},{"issue":"8","key":"2026091511065474300_cit15","doi-asserted-by":"publisher","DOI":"10.1126\/sciadv.aax0064","article-title":"A Prokaryotic-Eukaryotic\nHybrid Viral Vector for Delivery of Large\nCargos of Genes and Proteins into Human Cells","volume":"5","author":"Zhu","year":"2019","journal-title":"Sci. Adv."},{"key":"2026091511065474300_cit16","doi-asserted-by":"publisher","first-page":"108730","DOI":"10.1016\/j.jneumeth.2020.108730","article-title":"Methods for Mechanical\nDelivery of Viral Vectors into Rhesus Monkey Brain","volume":"339","author":"Fredericks","year":"2020","journal-title":"J. Neurosci. Methods"},{"key":"2026091511065474300_cit17","doi-asserted-by":"publisher","first-page":"2004595","DOI":"10.1002\/advs.202004595","article-title":"Microfluidic\nand Nanofluidic Intracellular Delivery","volume":"8","author":"Hur","year":"2021","journal-title":"Adv.\nSci."},{"key":"2026091511065474300_cit18","doi-asserted-by":"publisher","first-page":"2082","DOI":"10.1073\/pnas.1218705110","article-title":"A Vector-Free\nMicrofluidic Platform for Intracellular Delivery","volume":"110","author":"Sharei","year":"2013","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"2026091511065474300_cit19","doi-asserted-by":"publisher","first-page":"382","DOI":"10.1038\/s41467-023-44447-w","article-title":"High Throughput Intracellular\nDelivery by Viscoelastic Mechanoporation","volume":"15","author":"Sevenler","year":"2024","journal-title":"Nat.\nCommun."},{"key":"2026091511065474300_cit20","doi-asserted-by":"publisher","first-page":"2304122","DOI":"10.1002\/adma.202304122","article-title":"Engineering Efficient CAR-T Cells\nvia Electroactive\nNanoinjection","volume":"35","author":"Shokouhi","year":"2023","journal-title":"Adv. Mater."},{"issue":"3","key":"2026091511065474300_cit21","doi-asserted-by":"publisher","first-page":"2101","DOI":"10.1021\/acsnano.2c07852","article-title":"High-Throughput and Efficient Intracellular Delivery Method via a\nVibration-Assisted Nanoneedle\/Microfluidic Composite System","volume":"17","author":"Li","year":"2023","journal-title":"ACS Nano"},{"key":"2026091511065474300_cit22","doi-asserted-by":"publisher","first-page":"15991","DOI":"10.1021\/acs.analchem.5c02905","article-title":"A 3D Printed\nMeridian-Arrayed Microfluidic Device for Dual-Physical Fields Induced\nHighly Efficient Intracellular Delivery","volume":"97","author":"Li","year":"2025","journal-title":"Anal.\nChem."},{"issue":"14","key":"2026091511065474300_cit23","doi-asserted-by":"publisher","first-page":"1135","DOI":"10.1038\/sj.gt.3302071","article-title":"Gene Therapy Progress and Prospects: Adenoviral Vectors","volume":"10","author":"St Georget","year":"2003","journal-title":"Gene Ther."},{"issue":"16","key":"2026091511065474300_cit24","doi-asserted-by":"publisher","first-page":"3147","DOI":"10.1016\/j.biomaterials.2005.12.030","article-title":"Effective Transfection\nof Cells with Multi-Shell Calcium Phosphate\u2013DNA Nanoparticles","volume":"27","author":"Sokolova","year":"2006","journal-title":"Biomaterials"},{"issue":"8","key":"2026091511065474300_cit25","doi-asserted-by":"publisher","first-page":"1258","DOI":"10.1039\/b803212b","article-title":"Microfluidic Based\nSingle Cell Microinjection","volume":"8","author":"Adamo","year":"2008","journal-title":"Lab Chip"},{"issue":"3","key":"2026091511065474300_cit26","doi-asserted-by":"publisher","first-page":"035026","DOI":"10.1088\/0960-1317\/23\/3\/035026","article-title":"Microfluidic\nJet Injection for Delivering Macromolecules into Cells","volume":"23","author":"Adamo","year":"2013","journal-title":"J. Micromech. Microeng."},{"issue":"1","key":"2026091511065474300_cit27","doi-asserted-by":"publisher","first-page":"6806","DOI":"10.1038\/s41598-019-43340-1","article-title":"Nanostraw Membrane\nStamping for Direct Delivery of Molecules into Adhesive Cells","volume":"9","author":"Zhang","year":"2019","journal-title":"Sci. Rep."},{"issue":"21","key":"2026091511065474300_cit28","doi-asserted-by":"publisher","first-page":"8349","DOI":"10.1021\/acs.analchem.3c05331","article-title":"A Hybrid Nanotube\nStamp System in Intracellular Protein Delivery for Cancer Treatment\nand NMR Analytical Techniques","volume":"96","author":"Zhang","year":"2024","journal-title":"Anal. Chem."},{"issue":"12","key":"2026091511065474300_cit29","doi-asserted-by":"publisher","first-page":"2100069","DOI":"10.1002\/smsc.202100069","article-title":"High-Efficient\nand Dosage-Controllable Intracellular Cargo Delivery through Electrochemical\nMetal\u2013Organic Hybrid Nanogates","volume":"1","author":"Zhang","year":"2021","journal-title":"Small\nSci."},{"key":"2026091511065474300_cit30","doi-asserted-by":"publisher","DOI":"10.1002\/smsc.202500598","article-title":"A Nanotube Injector for Cytoplasmic Transfer and Enhanced\nMitochondrial Function","volume":"6","author":"Liu","year":"2026","journal-title":"Small Sci."},{"issue":"4498","key":"2026091511065474300_cit31","doi-asserted-by":"publisher","first-page":"1038","DOI":"10.1126\/science.212.4498.1038","article-title":"Polyphenolic Substance\nof Mytilus Edulis: Novel Adhesive\nContaining L-Dopa and Hydroxyproline","volume":"212","author":"Waite","year":"1981","journal-title":"Science"},{"issue":"5","key":"2026091511065474300_cit32","doi-asserted-by":"publisher","first-page":"2911","DOI":"10.1016\/S0021-9258(18)32805-9","article-title":"Evidence\nfor a Repeating 3,4-Dihydroxyphenylalanine- and Hydroxyproline-Containing\nDecapeptide in the Adhesive Protein of the Mussel, Mytilus Edulis\nL","volume":"258","author":"Waite","year":"1983","journal-title":"J. Biol. Chem."},{"issue":"4","key":"2026091511065474300_cit33","doi-asserted-by":"publisher","first-page":"393","DOI":"10.4139\/sfj.48.393","article-title":"Types and applications\nof electroless gold plating\nbaths","volume":"48","author":"Nishiyama","year":"1997","journal-title":"Hyo\u0305men Gijutsu"},{"issue":"2","key":"2026091511065474300_cit34","doi-asserted-by":"publisher","first-page":"92","DOI":"10.4139\/sfj.58.92","article-title":"Electroless\nGold Plating Process for Fine Pattern","volume":"58","author":"Watanabe","year":"2007","journal-title":"Hyo\u0305men\nGijutsu"},{"issue":"4","key":"2026091511065474300_cit35","doi-asserted-by":"publisher","first-page":"1739","DOI":"10.3390\/ma16041739","article-title":"Thermo-Compression\nBonding of Cu\/SnAg Pillar Bumps with Electroless\nPalladium Immersion Gold (EPIG) Surface Finish","volume":"16","author":"Jun","year":"2023","journal-title":"Materials"},{"issue":"7","key":"2026091511065474300_cit36","doi-asserted-by":"publisher","first-page":"2189","DOI":"10.1007\/s11696-020-01066-9","article-title":"Synthesis, Radical Scavenging, and\nAntimicrobial Activities of Core\u2013Shell Au\/Ni Microtubes","volume":"74","author":"Mashentseva","year":"2020","journal-title":"Chem. Pap."},{"issue":"6","key":"2026091511065474300_cit37","doi-asserted-by":"publisher","first-page":"1628","DOI":"10.1002\/bit.27326","article-title":"Cold Shock Proteins\nImprove E. coli Cell-free Synthesis in Terms of Soluble Yields of\nAggregation-prone Proteins","volume":"117","author":"Higuchi","year":"2020","journal-title":"Biotechnol. Bioeng."},{"issue":"6","key":"2026091511065474300_cit38","doi-asserted-by":"publisher","first-page":"2122","DOI":"10.1073\/pnas.94.6.2122","article-title":"Removal of a Cryptic\nIntron and Subcellular Localization of Green Fluorescent Protein Are\nRequired to Mark Transgenic Arabidopsis Plants Brightly","volume":"94","author":"Haseloff","year":"1997","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"issue":"1","key":"2026091511065474300_cit39","doi-asserted-by":"publisher","first-page":"22","DOI":"10.5685\/plmorphol.10.22","article-title":"Use of GFP\nin Higher Plants","volume":"10","author":"Niwa","year":"1998","journal-title":"Plant Morphol."},{"key":"2026091511065474300_cit40","doi-asserted-by":"publisher","first-page":"226844","DOI":"10.1016\/j.jpowsour.2019.226844","article-title":"High-Power Lactate\/O2 Enzymatic\nBiofuel Cell Based on Carbon Cloth Electrodes Modified with MgO-Templated\nCarbon","volume":"436","author":"Shitanda","year":"2019","journal-title":"J. Power Sources"},{"issue":"11","key":"2026091511065474300_cit41","first-page":"5726","article-title":"Increased Lactate in\nAML Blasts Upregulates TOX Expression, Leading to Exhaustion of CD8+\nCytolytic T Cells","volume":"11","author":"Chen","year":"2021","journal-title":"Am. J. Cancer Res."},{"key":"2026091511065474300_cit42","doi-asserted-by":"publisher","DOI":"10.1101\/2023.11.13.566874","article-title":"Elevated Lactate in Acute Myeloid\nLeukemia Bone Marrow Microenvironment Dysfunction, with a Dual Role\nof GPR81 in Macrophage Polarization and Leukemia Cell Growth","author":"Soto","year":"2023","journal-title":"bioRxiv"},{"issue":"4","key":"2026091511065474300_cit43","doi-asserted-by":"publisher","first-page":"1552","DOI":"10.1172\/JCI129204","article-title":"Immune Escape and Immunotherapy of Acute Myeloid Leukemia","volume":"130","author":"Vago","year":"2020","journal-title":"J. Clin. Invest."},{"issue":"18","key":"2026091511065474300_cit44","doi-asserted-by":"publisher","first-page":"8739","DOI":"10.1039\/D3NR05952A","article-title":"Recent Progress\nin Lactate Oxidase-Based Drug Delivery Systems for Enhanced Cancer\nTherapy","volume":"16","author":"Li","year":"2024","journal-title":"Nanoscale"},{"issue":"1","key":"2026091511065474300_cit45","doi-asserted-by":"publisher","first-page":"74","DOI":"10.1186\/s13046-017-0544-y","article-title":"Rapamycin\n(MTORC1 Inhibitor) Reduces the Production of Lactate and 2-Hydroxyglutarate\nOncometabolites in IDH1Mutant Fibrosarcoma Cells","volume":"36","author":"Hujber","year":"2017","journal-title":"J. Exp. Clin. Cancer Res."},{"issue":"3","key":"2026091511065474300_cit46","doi-asserted-by":"publisher","first-page":"1098","DOI":"10.1158\/1078-0432.CCR-18-1133","article-title":"Targeting\nCancer Cells and Tumor Microenvironment in Preclinical and Clinical\nModels of Hodgkin Lymphoma Using the Dual PI3K Delta\/Gamma Inhibitor\nRP6530","volume":"25","author":"Locatelli","year":"2019","journal-title":"Clin. Cancer Res."},{"issue":"3","key":"2026091511065474300_cit47","doi-asserted-by":"publisher","first-page":"973","DOI":"10.1039\/D2CS00479H","article-title":"Engineering Lactate-Modulating Nanomedicines\nfor Cancer Therapy","volume":"52","author":"Chen","year":"2023","journal-title":"Chem. Soc. Rev."},{"issue":"3","key":"2026091511065474300_cit48","doi-asserted-by":"publisher","first-page":"243","DOI":"10.4161\/cib.2.3.8165","article-title":"Tunneling\nnanotubes (TNT)","volume":"2","author":"Eugenin","year":"2009","journal-title":"Commun. Integr Biol."},{"issue":"5","key":"2026091511065474300_cit49","doi-asserted-by":"publisher","first-page":"313","DOI":"10.4264\/numa.79.5_313","article-title":"Intercellular\nMitochondrial Transfer via Tunneling Nanotubes","volume":"79","author":"Miki","year":"2020","journal-title":"J. Nihon Univ. Med. Assoc."},{"key":"2026091511065474300_cit50","doi-asserted-by":"publisher","first-page":"911","DOI":"10.1182\/blood-2019-125007","article-title":"Oxphos\nInhibition Induces Formation of Tunneling Nanotubes in AML Cells and\nFacilitates Mitochondrial Transfer from BM Stroma to AML That Contributes\nto Microenvironment-Mediated Drug-Resistance of AML","volume":"134","author":"Zhang","year":"2019","journal-title":"Blood"},{"issue":"10","key":"2026091511065474300_cit51","doi-asserted-by":"publisher","first-page":"1886","DOI":"10.1038\/s42255-024-01125-5","article-title":"Mitochondria Transfer-Based\nTherapies Reduce\nthe Morbidity and Mortality of Leigh Syndrome","volume":"6","author":"Nakai","year":"2024","journal-title":"Nat. Metab."},{"issue":"C","key":"2026091511065474300_cit52","doi-asserted-by":"publisher","first-page":"27","DOI":"10.1016\/j.ebiom.2017.05.016","article-title":"Mitochonic Acid 5 (MA-5) Facilitates ATP Synthase Oligomerization\nand Cell Survival in Various Mitochondrial Diseases","volume":"20","author":"Matsuhashi","year":"2017","journal-title":"EBioMedicine"}],"container-title":["Analytical Chemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acs.analchem.6c03151","content-type":"application\/pdf","content-version":"vor","intended-application":"unspecified"},{"URL":"https:\/\/pubs.acs.org\/ancham\/article-pdf\/98\/36\/26680\/68208028\/acs.analchem.6c03151.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/pubs.acs.org\/ancham\/article-pdf\/98\/36\/26680\/68208028\/acs.analchem.6c03151.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,15]],"date-time":"2026-09-15T15:52:08Z","timestamp":1789487528000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/ancham\/article\/98\/36\/26680\/5405766\/A-Bidirectional-Nanotube-Stamping-Platform-for"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,9,2]]},"references-count":52,"journal-issue":{"issue":"36","published-online":{"date-parts":[[2026,9,2]]},"published-print":{"date-parts":[[2026,9,15]]}},"URL":"https:\/\/doi.org\/10.1021\/acs.analchem.6c03151","relation":{},"ISSN":["0003-2700","1520-6882"],"issn-type":[{"value":"0003-2700","type":"print"},{"value":"1520-6882","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,9,2]]}}}