{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T00:43:35Z","timestamp":1791852215253,"version":"4.3.4"},"reference-count":45,"publisher":"American Chemical Society (ACS)","issue":"5","license":[{"start":{"date-parts":[[2018,2,12]],"date-time":"2018-02-12T00:00:00Z","timestamp":1518393600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2018,2,12]],"date-time":"2018-02-12T00:00:00Z","timestamp":1518393600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2018,2,12]],"date-time":"2018-02-12T00:00:00Z","timestamp":1518393600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-045"}],"funder":[{"DOI":"10.13039\/501100002338","name":"Ministry of Education of the People's Republic of China","doi-asserted-by":"publisher","award":["buctrc201706"],"award-info":[{"award-number":["buctrc201706"]}],"id":[{"id":"10.13039\/501100002338","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002338","name":"Ministry of Education of the People's Republic of China","doi-asserted-by":"publisher","award":["buctrc201720"],"award-info":[{"award-number":["buctrc201720"]}],"id":[{"id":"10.13039\/501100002338","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100007302","name":"Beijing University of Chemical Technology","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100007302","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["21475007"],"award-info":[{"award-number":["21475007"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["21505003"],"award-info":[{"award-number":["21505003"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["21675009"],"award-info":[{"award-number":["21675009"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["21725501"],"award-info":[{"award-number":["21725501"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2018,3,6]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>The sensitive and selective detection of hydrogen sulfide is of great importance due to its crucial role in pathological and physiological processes. Herein, we report a novel fluorescent platform, AuNCs@GC, for selective detection of hydrogen sulfide in living cells by impregnating the Au nanoclusters (AuNCs) into a biocompatible cationic polymer matrix, glycol-chitosan (GC) nanogel. The confinement effect significantly increased the emissive Au\u00ad(I) units, resulting in a 6-fold enhancement of quantum yield (from 6.38% to 36.42%). In addition, the prepared positively charged AuNCs@GC nanogel exhibits excellent selectivity and improved sensitivity to aqueous sulfides. Moreover, the as-fabricated AuNCs@GC showed very good biocompatibility and super fluorescence stability across the full pH range and good salt tolerance, which demonstrated excellent adaptability toward intracellular sulfide imaging.<\/jats:p>","DOI":"10.1021\/acs.analchem.7b04785","type":"journal-article","created":{"date-parts":[[2018,2,12]],"date-time":"2018-02-12T05:12:58Z","timestamp":1518412378000},"page":"3270-3275","source":"Crossref","is-referenced-by-count":95,"title":["Full-Range pH Stable Au-Clusters in Nanogel for Confinement-Enhanced\nEmission and Improved Sulfide Sensing in Living Cells"],"prefix":"10.1021","volume":"90","author":[{"given":"Xilin","family":"Bai","sequence":"first","affiliation":[{"name":"Beijing University of Chemical Technology , , ,","place":["Beijing, P. R. China, 100029"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6638-0040","authenticated-orcid":true,"given":"Suying","family":"Xu","sequence":"additional","affiliation":[{"name":"Beijing University of Chemical Technology , , ,","place":["Beijing, P. R. China, 100029"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5961-7764","authenticated-orcid":true,"given":"Leyu","family":"Wang","sequence":"additional","affiliation":[{"name":"Beijing University of Chemical Technology , , ,","place":["Beijing, P. R. China, 100029"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2018,2,12]]},"reference":[{"key":"2026081803235700000_cit1","doi-asserted-by":"publisher","first-page":"457","DOI":"10.1038\/nchembio.1834","volume":"11","author":"Mishanina","year":"2015","journal-title":"Nat. Chem. Biol."},{"key":"2026081803235700000_cit2","doi-asserted-by":"publisher","first-page":"329","DOI":"10.1038\/nrd4433","volume":"14","author":"Wallace","year":"2015","journal-title":"Nat.\nRev. Drug Discovery"},{"key":"2026081803235700000_cit3","doi-asserted-by":"publisher","first-page":"518","DOI":"10.1126\/science.1108581","volume":"308","author":"Blackstone","year":"2005","journal-title":"Science"},{"key":"2026081803235700000_cit4","doi-asserted-by":"publisher","first-page":"587","DOI":"10.1126\/science.1162667","volume":"322","author":"Yang","year":"2008","journal-title":"Science"},{"key":"2026081803235700000_cit5","doi-asserted-by":"publisher","first-page":"15560","DOI":"10.1073\/pnas.0705891104","volume":"104","author":"Elrod","year":"2007","journal-title":"Proc. Natl. Acad.\nSci. U. S. A."},{"key":"2026081803235700000_cit6","doi-asserted-by":"publisher","first-page":"1125","DOI":"10.1089\/ars.2009.2900","volume":"12","author":"Wallace","year":"2010","journal-title":"Antioxid. Redox\nSignaling"},{"key":"2026081803235700000_cit7","doi-asserted-by":"publisher","first-page":"1485","DOI":"10.1016\/S0006-291X(02)00422-9","volume":"293","author":"Eto","year":"2002","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"2026081803235700000_cit8","doi-asserted-by":"publisher","first-page":"459","DOI":"10.1042\/CS20110267","volume":"121","author":"Whiteman","year":"2011","journal-title":"Clin. Sci."},{"key":"2026081803235700000_cit9","doi-asserted-by":"publisher","first-page":"233","DOI":"10.1016\/j.bios.2017.05.006","volume":"96","author":"Manibalan","year":"2017","journal-title":"Biosens. Bioelectron."},{"key":"2026081803235700000_cit10","doi-asserted-by":"publisher","first-page":"5382","DOI":"10.1021\/acs.analchem.7b00069","volume":"89","author":"Wang","year":"2017","journal-title":"Anal. Chem."},{"key":"2026081803235700000_cit11","doi-asserted-by":"publisher","first-page":"311","DOI":"10.1002\/adfm.201670014","volume":"26","author":"Peng","year":"2016","journal-title":"Adv. Funct. Mater."},{"key":"2026081803235700000_cit12","doi-asserted-by":"publisher","first-page":"505","DOI":"10.1248\/cpb.c13-00988","volume":"62","author":"Zhang","year":"2014","journal-title":"Chem.\nPharm. Bull."},{"key":"2026081803235700000_cit13","doi-asserted-by":"publisher","first-page":"12234","DOI":"10.1039\/C4CC03312D","volume":"50","author":"Yu","year":"2014","journal-title":"Chem.\nCommun."},{"key":"2026081803235700000_cit14","doi-asserted-by":"publisher","first-page":"4596","DOI":"10.1039\/C4CS00298A","volume":"44","author":"Lin","year":"2015","journal-title":"Chem. Soc. Rev."},{"key":"2026081803235700000_cit15","doi-asserted-by":"publisher","first-page":"1801","DOI":"10.1021\/acs.analchem.6b04114","volume":"89","author":"Gong","year":"2017","journal-title":"Anal. Chem."},{"key":"2026081803235700000_cit16","doi-asserted-by":"publisher","first-page":"9365","DOI":"10.1002\/anie.201603813","volume":"55","author":"Sarkar","year":"2016","journal-title":"Angew. Chem., Int. Ed."},{"key":"2026081803235700000_cit17","doi-asserted-by":"publisher","first-page":"5320","DOI":"10.1021\/nn4011686","volume":"7","author":"Lin","year":"2013","journal-title":"ACS Nano"},{"key":"2026081803235700000_cit18","doi-asserted-by":"publisher","first-page":"11459","DOI":"10.1021\/ac503622n","volume":"86","author":"Ma","year":"2014","journal-title":"Anal. Chem."},{"key":"2026081803235700000_cit19","doi-asserted-by":"publisher","first-page":"2551","DOI":"10.1039\/c3sc50369k","volume":"4","author":"Wang","year":"2013","journal-title":"Chem. Sci."},{"key":"2026081803235700000_cit20","doi-asserted-by":"publisher","first-page":"1123","DOI":"10.1021\/ac402894z","volume":"86","author":"Yuan","year":"2014","journal-title":"Anal. Chem."},{"key":"2026081803235700000_cit21","doi-asserted-by":"publisher","first-page":"6210","DOI":"10.1021\/acs.analchem.7b01175","volume":"89","author":"Zhang","year":"2017","journal-title":"Anal. Chem."},{"key":"2026081803235700000_cit22","doi-asserted-by":"publisher","first-page":"502","DOI":"10.1039\/C2CC37725J","volume":"49","author":"Wan","year":"2013","journal-title":"Chem. Commun."},{"key":"2026081803235700000_cit23","doi-asserted-by":"publisher","first-page":"21461","DOI":"10.1021\/am5064603","volume":"6","author":"Zhu","year":"2014","journal-title":"ACS Appl. Mater. Interfaces"},{"key":"2026081803235700000_cit24","doi-asserted-by":"publisher","first-page":"371","DOI":"10.1103\/RevModPhys.77.371","volume":"77","author":"Baletto","year":"2005","journal-title":"Rev. Mod. Phys."},{"key":"2026081803235700000_cit25","doi-asserted-by":"publisher","first-page":"5006","DOI":"10.1002\/adfm.201501433","volume":"25","author":"Tian","year":"2015","journal-title":"Adv. Funct. Mater."},{"key":"2026081803235700000_cit26","doi-asserted-by":"publisher","first-page":"10275","DOI":"10.1021\/acs.analchem.6b03011","volume":"88","author":"Zang","year":"2016","journal-title":"Anal.\nChem."},{"key":"2026081803235700000_cit27","doi-asserted-by":"publisher","first-page":"9496","DOI":"10.1021\/ja9037017","volume":"131","author":"Ai","year":"2009","journal-title":"J. Am.\nChem. Soc."},{"key":"2026081803235700000_cit28","doi-asserted-by":"publisher","first-page":"951","DOI":"10.1002\/adfm.200902062","volume":"20","author":"Liu","year":"2010","journal-title":"Adv. Funct. Mater."},{"key":"2026081803235700000_cit29","doi-asserted-by":"publisher","first-page":"2568","DOI":"10.1021\/nl101225f","volume":"10","author":"Wu","year":"2010","journal-title":"Nano\nLett."},{"key":"2026081803235700000_cit30","doi-asserted-by":"publisher","first-page":"4128","DOI":"10.1039\/C7NR00073A","volume":"9","author":"Cao","year":"2017","journal-title":"Nanoscale"},{"key":"2026081803235700000_cit31","doi-asserted-by":"publisher","first-page":"8676","DOI":"10.1021\/acs.chemmater.6b03838","volume":"28","author":"Oh","year":"2016","journal-title":"Chem. Mater."},{"key":"2026081803235700000_cit32","doi-asserted-by":"publisher","first-page":"5006","DOI":"10.1002\/adfm.201501433","volume":"25","author":"Tian","year":"2015","journal-title":"Adv. Funct. Mater."},{"key":"2026081803235700000_cit33","doi-asserted-by":"publisher","first-page":"2591","DOI":"10.1021\/acsnano.5b07596","volume":"10","author":"Yahia-Ammar","year":"2016","journal-title":"ACS Nano"},{"key":"2026081803235700000_cit34","doi-asserted-by":"publisher","first-page":"401","DOI":"10.1016\/j.nantod.2011.06.004","volume":"6","author":"Shang","year":"2011","journal-title":"Nano Today"},{"key":"2026081803235700000_cit35","doi-asserted-by":"publisher","first-page":"16662","DOI":"10.1021\/ja306199p","volume":"134","author":"Luo","year":"2012","journal-title":"J. Am. Chem. Soc."},{"key":"2026081803235700000_cit36","doi-asserted-by":"publisher","first-page":"8244","DOI":"10.1021\/jacs.5b04210","volume":"137","author":"Pyo","year":"2015","journal-title":"J.\nAm. Chem. Soc."},{"key":"2026081803235700000_cit37","doi-asserted-by":"publisher","first-page":"4009","DOI":"10.1021\/acs.chemmater.6b01431","volume":"28","author":"Goswami","year":"2016","journal-title":"Chem. Mater."},{"key":"2026081803235700000_cit38","doi-asserted-by":"publisher","first-page":"17799","DOI":"10.1021\/acsami.7b04576","volume":"9","author":"Wang","year":"2017","journal-title":"ACS\nAppl. Mater. Interfaces"},{"issue":"172","key":"2026081803235700000_cit39","doi-asserted-by":"publisher","first-page":"171","DOI":"10.1186\/s11671-015-0879-2","volume":"10","author":"Mansur","year":"2015","journal-title":"Nanoscale Res. Lett."},{"key":"2026081803235700000_cit40","doi-asserted-by":"publisher","first-page":"787","DOI":"10.1002\/jbm.a.31430","volume":"83A","author":"Knight","year":"2007","journal-title":"J. Biomed. Mater.\nRes., Part A"},{"key":"2026081803235700000_cit41","doi-asserted-by":"publisher","first-page":"10078","DOI":"10.1021\/ja203661j","volume":"133","author":"Lippert","year":"2011","journal-title":"J. Am. Chem. Soc."},{"key":"2026081803235700000_cit42","doi-asserted-by":"publisher","first-page":"10327","DOI":"10.1002\/anie.201104305","volume":"50","author":"Liu","year":"2011","journal-title":"Angew.\nChem., Int. Ed."},{"key":"2026081803235700000_cit43","doi-asserted-by":"publisher","first-page":"587","DOI":"10.1126\/science.1162667","volume":"322","author":"Yang","year":"2008","journal-title":"Science"},{"key":"2026081803235700000_cit44","doi-asserted-by":"publisher","first-page":"495","DOI":"10.1038\/ncomms1506","volume":"2","author":"Qian","year":"2011","journal-title":"Nat.\nCommun."},{"key":"2026081803235700000_cit45","doi-asserted-by":"publisher","first-page":"7505","DOI":"10.1039\/C5CC01184A","volume":"51","author":"Zhang","year":"2015","journal-title":"Chem.\nCommun."}],"container-title":["Analytical Chemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acs.analchem.7b04785","content-type":"application\/pdf","content-version":"vor","intended-application":"unspecified"},{"URL":"https:\/\/pubs.acs.org\/ancham\/article-pdf\/90\/5\/3270\/17731282\/ac7b04785.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/pubs.acs.org\/ancham\/article-pdf\/90\/5\/3270\/17731282\/ac7b04785.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T08:59:38Z","timestamp":1787043578000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/ancham\/article\/90\/5\/3270\/818798\/Full-Range-pH-Stable-Au-Clusters-in-Nanogel-for"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,2,12]]},"references-count":45,"journal-issue":{"issue":"5","published-online":{"date-parts":[[2018,2,12]]},"published-print":{"date-parts":[[2018,3,6]]}},"URL":"https:\/\/doi.org\/10.1021\/acs.analchem.7b04785","relation":{},"ISSN":["0003-2700","1520-6882"],"issn-type":[{"value":"0003-2700","type":"print"},{"value":"1520-6882","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,2,12]]}}}