{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,17]],"date-time":"2026-09-17T02:11:59Z","timestamp":1789611119851,"version":"build-2803163510"},"reference-count":60,"publisher":"American Chemical Society (ACS)","issue":"11","funder":[{"DOI":"10.13039\/501100003329","name":"Ministerio de Econom?a y Competitividad","doi-asserted-by":"publisher","award":["CTQ2014-56777-R"],"award-info":[{"award-number":["CTQ2014-56777-R"]}],"id":[{"id":"10.13039\/501100003329","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003176","name":"Ministerio de Educaci?n, Cultura y Deporte","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003176","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Anal. Chem."],"published-print":{"date-parts":[[2018,6,5]]},"DOI":"10.1021\/acs.analchem.8b00405","type":"journal-article","created":{"date-parts":[[2018,5,7]],"date-time":"2018-05-07T05:10:12Z","timestamp":1525669812000},"page":"6618-6625","source":"Crossref","is-referenced-by-count":35,"title":["Analysis of Circulating microRNAs and Their Post-Transcriptional Modifications in Cancer Serum by On-Line Solid-Phase Extraction\u2013Capillary Electrophoresis\u2013Mass Spectrometry"],"prefix":"10.1021","volume":"90","author":[{"given":"Roger","family":"Pero-Gascon","sequence":"first","affiliation":[{"name":"Department of Chemical Engineering and Analytical Chemistry, Institute for Research on Nutrition and Food Safety (INSA\u00b7UB), University of Barcelona, Barcelona 08028, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Victoria","family":"Sanz-Nebot","sequence":"additional","affiliation":[{"name":"Department of Chemical Engineering and Analytical Chemistry, Institute for Research on Nutrition and Food Safety (INSA\u00b7UB), University of Barcelona, Barcelona 08028, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0514-599X","authenticated-orcid":true,"given":"Maxim V.","family":"Berezovski","sequence":"additional","affiliation":[{"name":"Department of Chemistry and Biomolecular Sciences, University of Ottawa, Ottawa, Ontario K1N 6N5, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1688-1477","authenticated-orcid":true,"given":"Fernando","family":"Benavente","sequence":"additional","affiliation":[{"name":"Department of Chemical Engineering and Analytical Chemistry, Institute for Research on Nutrition and Food Safety (INSA\u00b7UB), University of Barcelona, Barcelona 08028, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2018,5,7]]},"reference":[{"key":"ref1\/cit1","doi-asserted-by":"publisher","DOI":"10.1038\/nrg2843"},{"key":"ref2\/cit2","doi-asserted-by":"publisher","DOI":"10.4110\/in.2011.11.3.135"},{"key":"ref3\/cit3","doi-asserted-by":"publisher","DOI":"10.1016\/j.molcel.2010.06.010"},{"key":"ref4\/cit4","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkq601"},{"key":"ref5\/cit5","doi-asserted-by":"publisher","DOI":"10.1161\/ATVBAHA.112.300741"},{"key":"ref6\/cit6","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0804549105"},{"key":"ref7\/cit7","doi-asserted-by":"publisher","DOI":"10.1186\/1476-4598-9-306"},{"key":"ref8\/cit8","doi-asserted-by":"publisher","DOI":"10.1038\/cr.2008.282"},{"key":"ref9\/cit9","doi-asserted-by":"publisher","DOI":"10.1038\/nrclinonc.2014.5"},{"key":"ref10\/cit10","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2141.2008.07077.x"},{"key":"ref11\/cit11","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkp1235"},{"key":"ref12\/cit12","doi-asserted-by":"publisher","DOI":"10.1007\/978-1-62703-357-2_21"},{"key":"ref13\/cit13","doi-asserted-by":"crossref","DOI":"10.1007\/978-1-60761-629-0","volume-title":"RT-PCR Protocols","author":"King N.","year":"2010","edition":"2"},{"key":"ref14\/cit14","doi-asserted-by":"crossref","first-page":"409","DOI":"10.1007\/978-3-319-22671-2_21","volume-title":"microRNA: Medical Evidence","volume":"888","author":"Roden C.","year":"2015"},{"key":"ref15\/cit15","doi-asserted-by":"publisher","DOI":"10.1101\/gr.118059.110"},{"key":"ref16\/cit16","doi-asserted-by":"publisher","DOI":"10.1002\/elps.201600366"},{"key":"ref17\/cit17","doi-asserted-by":"publisher","DOI":"10.1007\/s00604-017-2084-8"},{"key":"ref18\/cit18","doi-asserted-by":"publisher","DOI":"10.1002\/jssc.201500973"},{"key":"ref19\/cit19","doi-asserted-by":"publisher","DOI":"10.1002\/elps.201600370"},{"key":"ref20\/cit20","doi-asserted-by":"publisher","DOI":"10.1016\/j.tig.2014.07.001"},{"key":"ref21\/cit21","doi-asserted-by":"publisher","DOI":"10.1007\/s00216-015-9277-y"},{"key":"ref22\/cit22","doi-asserted-by":"publisher","DOI":"10.1002\/elps.201600331"},{"key":"ref23\/cit23","doi-asserted-by":"publisher","DOI":"10.1002\/elps.201600292"},{"key":"ref24\/cit24","doi-asserted-by":"publisher","DOI":"10.1002\/elps.201600289"},{"key":"ref25\/cit25","doi-asserted-by":"publisher","DOI":"10.1002\/elps.201500401"},{"key":"ref26\/cit26","doi-asserted-by":"publisher","DOI":"10.1002\/elps.201100017"},{"key":"ref27\/cit27","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1007\/978-1-4939-4014-1_6","volume-title":"Capillary Electrophoresis of Proteins and Peptides: Methods and Protocols","author":"Benavente F.","year":"2016"},{"key":"ref28\/cit28","doi-asserted-by":"publisher","DOI":"10.1016\/j.chroma.2006.11.092"},{"key":"ref29\/cit29","doi-asserted-by":"publisher","DOI":"10.1002\/elps.200700872"},{"key":"ref30\/cit30","doi-asserted-by":"publisher","DOI":"10.1002\/elps.201400293"},{"key":"ref31\/cit31","doi-asserted-by":"publisher","DOI":"10.1002\/elps.201400119"},{"key":"ref32\/cit32","doi-asserted-by":"publisher","DOI":"10.1002\/elps.201500495"},{"key":"ref33\/cit33","doi-asserted-by":"publisher","DOI":"10.1016\/j.talanta.2017.03.104"},{"key":"ref34\/cit34","doi-asserted-by":"publisher","DOI":"10.1038\/srep19529"},{"key":"ref35\/cit35","doi-asserted-by":"publisher","DOI":"10.3389\/fgene.2013.00083"},{"key":"ref36\/cit36","doi-asserted-by":"publisher","DOI":"10.1016\/j.molimm.2012.02.001"},{"key":"ref37\/cit37","doi-asserted-by":"publisher","DOI":"10.1016\/j.jgo.2017.04.004"},{"key":"ref38\/cit38","volume-title":"High Performance Capillary Electrophoresis","author":"Lauer H. H.","year":"2014","edition":"2"},{"key":"ref39\/cit39","doi-asserted-by":"publisher","DOI":"10.1016\/j.aca.2011.11.057"},{"key":"ref40\/cit40","doi-asserted-by":"publisher","DOI":"10.1016\/j.aca.2013.06.030"},{"key":"ref41\/cit41","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/22.19.3895"},{"key":"ref42\/cit42","doi-asserted-by":"publisher","DOI":"10.1007\/s13361-013-0759-x"},{"key":"ref43\/cit43","doi-asserted-by":"publisher","DOI":"10.1002\/rcm.7596"},{"key":"ref44\/cit44","unstructured":"Lam, B.; Elmogy, M.; Geng, S.S.; Roberts, P.; Rghei, N.; Haj-Ahmad, Y. Silicon Carbide as a Novel RNA Affinity Medium with Improved Sensitivity and Size Diversity. https:\/\/norgenbiotek.com\/sites\/default\/files\/resources\/Poster-13-Silicon-Carbide-as-a-Novel-RNA-Affinity-Medium-with-Improved-Sensitivity-and-Size-Diversity.pdf (accessed May 2, 2018)."},{"key":"ref45\/cit45","unstructured":"Norgen Biotek\nCorporation.  microRNA Purification\nKit. https:\/\/norgenbiotek.com\/sites\/default\/files\/resources\/MicroRNA-Purification-Kit-Insert-PI21300-22-M14_0.pdf (accessed May 2, 2018)."},{"key":"ref46\/cit46","doi-asserted-by":"publisher","DOI":"10.1007\/s00216-013-7178-5"},{"key":"ref47\/cit47","doi-asserted-by":"publisher","DOI":"10.1016\/0003-2697(80)90477-7"},{"key":"ref48\/cit48","doi-asserted-by":"publisher","DOI":"10.1271\/bbb.120767"},{"key":"ref49\/cit49","doi-asserted-by":"publisher","DOI":"10.1373\/clinchem.2011.172767"},{"key":"ref50\/cit50","doi-asserted-by":"publisher","DOI":"10.3892\/ijo.2014.2743"},{"key":"ref51\/cit51","doi-asserted-by":"publisher","DOI":"10.1186\/s12957-016-0842-4"},{"key":"ref52\/cit52","doi-asserted-by":"publisher","DOI":"10.18632\/oncotarget.12028"},{"key":"ref53\/cit53","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2013-08-514117"},{"key":"ref54\/cit54","doi-asserted-by":"publisher","DOI":"10.1186\/1476-4598-9-123"},{"key":"ref55\/cit55","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkq1027"},{"key":"ref56\/cit56","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1019557108"},{"key":"ref57\/cit57","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa050995"},{"key":"ref58\/cit58","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2006-12-062398"},{"key":"ref59\/cit59","doi-asserted-by":"publisher","DOI":"10.1053\/j.seminoncol.2016.02.015"},{"key":"ref60\/cit60","doi-asserted-by":"publisher","DOI":"10.3892\/br.2016.747"}],"container-title":["Analytical Chemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acs.analchem.8b00405","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,4,26]],"date-time":"2023-04-26T11:54:17Z","timestamp":1682510057000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/acs.analchem.8b00405"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,5,7]]},"references-count":60,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2018,6,5]]}},"alternative-id":["10.1021\/acs.analchem.8b00405"],"URL":"https:\/\/doi.org\/10.1021\/acs.analchem.8b00405","relation":{},"ISSN":["0003-2700","1520-6882"],"issn-type":[{"value":"0003-2700","type":"print"},{"value":"1520-6882","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,5,7]]}}}