{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,26]],"date-time":"2026-01-26T00:29:53Z","timestamp":1769387393478,"version":"3.49.0"},"reference-count":78,"publisher":"American Chemical Society (ACS)","issue":"10","license":[{"start":{"date-parts":[[2019,4,25]],"date-time":"2019-04-25T00:00:00Z","timestamp":1556150400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2019,4,25]],"date-time":"2019-04-25T00:00:00Z","timestamp":1556150400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2019,4,25]],"date-time":"2019-04-25T00:00:00Z","timestamp":1556150400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-045"}],"funder":[{"DOI":"10.13039\/100000054","name":"National Cancer Institute","doi-asserted-by":"publisher","award":["P30CA033572"],"award-info":[{"award-number":["P30CA033572"]}],"id":[{"id":"10.13039\/100000054","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000050","name":"National Heart, Lung, and Blood Institute","doi-asserted-by":"publisher","award":["P01HL129941"],"award-info":[{"award-number":["P01HL129941"]}],"id":[{"id":"10.13039\/100000050","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Anal. Chem."],"published-print":{"date-parts":[[2019,5,21]]},"DOI":"10.1021\/acs.analchem.8b03828","type":"journal-article","created":{"date-parts":[[2019,4,25]],"date-time":"2019-04-25T16:31:45Z","timestamp":1556209905000},"page":"6440-6453","source":"Crossref","is-referenced-by-count":36,"title":["The Plethora of Angiotensin-Converting Enzyme-Processed Peptides in Mouse Plasma"],"prefix":"10.1021","volume":"91","author":[{"given":"Margarita","family":"Semis","sequence":"first","affiliation":[{"name":"Department of Molecular Imaging and Therapy, Diabetes and Metabolism Research Institute, Beckman Research Institute of the City of Hope, Duarte, California 91010, United States"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gabriel B.","family":"Gugiu","sequence":"additional","affiliation":[{"name":"Department of Molecular Imaging and Therapy, Diabetes and Metabolism Research Institute, Beckman Research Institute of the City of Hope, Duarte, California 91010, United States"},{"name":"Mass Spectrometry & Proteomics Core Facility, Beckman Research Institute of the City of Hope, Duarte, California 91010, United States"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ellen A.","family":"Bernstein","sequence":"additional","affiliation":[{"name":"Departments of Biomedical Sciences, Pathology and Laboratory Medicine, Cedars-Sinai Medical Center, Los Angeles, California 90048, United States"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kenneth E.","family":"Bernstein","sequence":"additional","affiliation":[{"name":"Departments of Biomedical Sciences, Pathology and Laboratory Medicine, Cedars-Sinai Medical Center, Los Angeles, California 90048, United States"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9506-671X","authenticated-orcid":true,"given":"Markus","family":"Kalkum","sequence":"additional","affiliation":[{"name":"Department of Molecular Imaging and Therapy, Diabetes and Metabolism Research Institute, Beckman Research Institute of the City of Hope, Duarte, California 91010, United States"},{"name":"Mass Spectrometry & Proteomics Core Facility, Beckman Research Institute of the City of Hope, Duarte, California 91010, United States"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"316","published-online":{"date-parts":[[2019,4,25]]},"reference":[{"key":"ref1\/cit1","doi-asserted-by":"publisher","DOI":"10.1002\/cphy.c130040"},{"key":"ref2\/cit2","doi-asserted-by":"publisher","DOI":"10.1007\/s40292-015-0120-5"},{"key":"ref3\/cit3","doi-asserted-by":"publisher","DOI":"10.2298\/SARH1412756I"},{"key":"ref4\/cit4","doi-asserted-by":"publisher","DOI":"10.1186\/s40885-016-0042-0"},{"key":"ref5\/cit5","doi-asserted-by":"publisher","DOI":"10.1016\/S0014-5793(02)03640-2"},{"key":"ref6\/cit6","doi-asserted-by":"publisher","DOI":"10.4149\/endo_2013_01_39"},{"key":"ref7\/cit7","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2164-6-172"},{"key":"ref8\/cit8","doi-asserted-by":"publisher","DOI":"10.1021\/bi9928905"},{"key":"ref9\/cit9","doi-asserted-by":"publisher","DOI":"10.1016\/j.coph.2010.11.001"},{"issue":"5","key":"ref10\/cit10","first-page":"953","volume":"74","author":"Esther C. R.","year":"1996","journal-title":"Lab. Invest."},{"key":"ref11\/cit11","doi-asserted-by":"publisher","DOI":"10.1038\/nm1105-1140"},{"key":"ref11.1\/ref11.1_1","doi-asserted-by":"publisher","DOI":"10.1038\/nm1105-1142"},{"key":"ref12\/cit12","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M110.163782"},{"key":"ref13\/cit13","doi-asserted-by":"publisher","DOI":"10.2353\/ajpath.2007.061205"},{"key":"ref14\/cit14","doi-asserted-by":"publisher","DOI":"10.1172\/JCI66541"},{"key":"ref15\/cit15","doi-asserted-by":"publisher","DOI":"10.1038\/ni.2107"},{"key":"ref16\/cit16","doi-asserted-by":"publisher","DOI":"10.1038\/labinvest.2017.32"},{"key":"ref17\/cit17","doi-asserted-by":"publisher","DOI":"10.1161\/ATVBAHA.113.301777"},{"key":"ref18\/cit18","doi-asserted-by":"publisher","DOI":"10.1161\/01.ATV.0000098653.74209.C6"},{"key":"ref19\/cit19","doi-asserted-by":"publisher","DOI":"10.1111\/ans.12670"},{"key":"ref20\/cit20","doi-asserted-by":"publisher","DOI":"10.1097\/MEG.0000000000000355"},{"key":"ref21\/cit21","doi-asserted-by":"publisher","DOI":"10.3389\/fphar.2015.00075"},{"key":"ref22\/cit22","doi-asserted-by":"publisher","DOI":"10.1152\/physiolgenomics.00145.2004"},{"key":"ref23\/cit23","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2016-11-752006"},{"key":"ref24\/cit24","doi-asserted-by":"publisher","DOI":"10.1152\/ajprenal.1998.274.1.F43"},{"key":"ref25\/cit25","doi-asserted-by":"publisher","DOI":"10.1016\/S0735-1097(02)01763-1"},{"key":"ref26\/cit26","doi-asserted-by":"publisher","DOI":"10.1172\/JCI116350"},{"key":"ref27\/cit27","first-page":"36E","volume":"16","author":"Vaughan D.","year":"2000","journal-title":"Can. J. Cardiol."},{"key":"ref28\/cit28","doi-asserted-by":"publisher","DOI":"10.1097\/00004872-200502000-00022"},{"key":"ref29\/cit29","doi-asserted-by":"publisher","DOI":"10.1038\/nrneph.2018.15"},{"key":"ref30\/cit30","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-4159.1972.tb01298.x"},{"key":"ref31\/cit31","doi-asserted-by":"publisher","DOI":"10.1124\/pr.112.006809"},{"key":"ref32\/cit32","doi-asserted-by":"publisher","DOI":"10.2174\/1381612033455459"},{"key":"ref33\/cit33","doi-asserted-by":"publisher","DOI":"10.1016\/j.peptides.2003.12.010"},{"key":"ref34\/cit34","doi-asserted-by":"crossref","first-page":"480","DOI":"10.1016\/B978-0-12-382219-2.00098-3","volume-title":"Handbook of Proteolytic Enzymes","author":"Sturrock E. D.","year":"2013"},{"key":"ref35\/cit35","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M212030200"},{"key":"ref36\/cit36","doi-asserted-by":"crossref","first-page":"1386","DOI":"10.1016\/B978-0-12-385095-9.00188-3","volume-title":"Handbook of Biologically Active Peptides","author":"Campbell D. J.","year":"2013","edition":"2"},{"key":"ref37\/cit37","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M400149200"},{"key":"ref38\/cit38","doi-asserted-by":"publisher","DOI":"10.1161\/HYPERTENSIONAHA.107.097865"},{"key":"ref39\/cit39","doi-asserted-by":"publisher","DOI":"10.1016\/0006-291X(90)91766-L"},{"issue":"7","key":"ref40\/cit40","doi-asserted-by":"crossref","first-page":"1399","DOI":"10.1093\/clinchem\/29.7.1399","volume":"29","author":"Neels H. M.","year":"1983","journal-title":"Clin. Chem."},{"key":"ref41\/cit41","doi-asserted-by":"publisher","DOI":"10.1016\/j.phymed.2004.07.002"},{"key":"ref42\/cit42","doi-asserted-by":"publisher","DOI":"10.1007\/BF02192855"},{"key":"ref43\/cit43","doi-asserted-by":"publisher","DOI":"10.1038\/nbt.2839"},{"key":"ref44\/cit44","doi-asserted-by":"publisher","DOI":"10.1101\/gr.849004"},{"key":"ref45\/cit45","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0045012"},{"key":"ref46\/cit46","doi-asserted-by":"publisher","DOI":"10.1016\/0076-6879(95)48020-X"},{"key":"ref47\/cit47","doi-asserted-by":"publisher","DOI":"10.1007\/978-1-4939-7057-5_6"},{"key":"ref48\/cit48","doi-asserted-by":"publisher","DOI":"10.1016\/j.dib.2018.04.018"},{"key":"ref49\/cit49","doi-asserted-by":"publisher","DOI":"10.1002\/rcm.8183"},{"key":"ref50\/cit50","doi-asserted-by":"publisher","DOI":"10.1002\/prca.201700163"},{"key":"ref51\/cit51","doi-asserted-by":"publisher","DOI":"10.1074\/mcp.RA117.000020"},{"key":"ref52\/cit52","doi-asserted-by":"publisher","DOI":"10.1002\/pmic.201700401"},{"key":"ref53\/cit53","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkt1251"},{"key":"ref54\/cit54","doi-asserted-by":"publisher","DOI":"10.1016\/0161-5890(89)90112-0"},{"key":"ref55\/cit55","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.1200856"},{"key":"ref56\/cit56","doi-asserted-by":"publisher","DOI":"10.1172\/JCI65861"},{"key":"ref57\/cit57","doi-asserted-by":"publisher","DOI":"10.1002\/art.22645"},{"key":"ref58\/cit58","doi-asserted-by":"publisher","DOI":"10.1002\/pmic.200900513"},{"key":"ref59\/cit59","doi-asserted-by":"publisher","DOI":"10.1016\/j.jprot.2013.04.029"},{"key":"ref60\/cit60","doi-asserted-by":"publisher","DOI":"10.1309\/AJCPG91UXBYFNRVO"},{"key":"ref61\/cit61","doi-asserted-by":"publisher","DOI":"10.1016\/S0009-8981(99)00221-1"},{"key":"ref62\/cit62","doi-asserted-by":"publisher","DOI":"10.1006\/bbrc.1998.8834"},{"key":"ref63\/cit63","doi-asserted-by":"publisher","DOI":"10.1016\/0024-3205(95)00217-T"},{"key":"ref64\/cit64","doi-asserted-by":"publisher","DOI":"10.1021\/pr050046x"},{"key":"ref65\/cit65","doi-asserted-by":"publisher","DOI":"10.1007\/s00005-013-0254-x"},{"key":"ref66\/cit66","doi-asserted-by":"publisher","DOI":"10.1016\/j.kint.2016.02.036"},{"key":"ref67\/cit67","doi-asserted-by":"publisher","DOI":"10.1016\/j.semnephrol.2013.08.005"},{"key":"ref68\/cit68","doi-asserted-by":"publisher","DOI":"10.1053\/j.ajkd.2015.03.040"},{"key":"ref69\/cit69","doi-asserted-by":"publisher","DOI":"10.1007\/s00467-015-3310-4"},{"key":"ref70\/cit70","doi-asserted-by":"publisher","DOI":"10.5527\/wjn.v4.i2.169"},{"key":"ref71\/cit71","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.176.3.1305"},{"key":"ref72\/cit72","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0158871"},{"key":"ref73\/cit73","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-017-03344-1"},{"key":"ref74\/cit74","doi-asserted-by":"publisher","DOI":"10.1053\/j.ajkd.2014.06.035"},{"key":"ref75\/cit75","doi-asserted-by":"publisher","DOI":"10.12659\/MSM.903102"},{"key":"ref76\/cit76","doi-asserted-by":"publisher","DOI":"10.3109\/08860229509037600"},{"issue":"6","key":"ref77\/cit77","first-page":"327","volume":"39","author":"Jacob C.","year":"1993","journal-title":"Clin. Nephrol."}],"container-title":["Analytical Chemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acs.analchem.8b03828","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,4,27]],"date-time":"2023-04-27T16:09:31Z","timestamp":1682611771000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/acs.analchem.8b03828"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,4,25]]},"references-count":78,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2019,5,21]]}},"alternative-id":["10.1021\/acs.analchem.8b03828"],"URL":"https:\/\/doi.org\/10.1021\/acs.analchem.8b03828","relation":{},"ISSN":["0003-2700","1520-6882"],"issn-type":[{"value":"0003-2700","type":"print"},{"value":"1520-6882","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,4,25]]}}}