{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,9]],"date-time":"2026-06-09T22:49:02Z","timestamp":1781045342898,"version":"3.54.1"},"reference-count":82,"publisher":"American Chemical Society (ACS)","issue":"10","license":[{"start":{"date-parts":[[2019,4,24]],"date-time":"2019-04-24T00:00:00Z","timestamp":1556064000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2019,4,24]],"date-time":"2019-04-24T00:00:00Z","timestamp":1556064000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2019,4,24]],"date-time":"2019-04-24T00:00:00Z","timestamp":1556064000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-045"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["21621003"],"award-info":[{"award-number":["21621003"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["21675097"],"award-info":[{"award-number":["21675097"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["21775084"],"award-info":[{"award-number":["21775084"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["21707079"],"award-info":[{"award-number":["21707079"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Anal. Chem."],"published-print":{"date-parts":[[2019,5,21]]},"DOI":"10.1021\/acs.analchem.9b00490","type":"journal-article","created":{"date-parts":[[2019,4,24]],"date-time":"2019-04-24T11:21:03Z","timestamp":1556104863000},"page":"6608-6615","source":"Crossref","is-referenced-by-count":33,"title":["Enhancing Catalytic Activity of Uranyl-Dependent DNAzyme by Flexible Linker Insertion for More Sensitive Detection of Uranyl Ion"],"prefix":"10.1021","volume":"91","author":[{"given":"Mengli","family":"Feng","sequence":"first","affiliation":[{"name":"Department of Chemistry, Beijing Key Laboratory for Microanalytical Methods and Instrumentation, Key Laboratory of Bioorganic Phosphorus Chemistry and Chemical Biology (Ministry of Education), Tsinghua University, Beijing 100084, People\u2019s Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chunmei","family":"Gu","sequence":"additional","affiliation":[{"name":"Department of Chemistry, Beijing Key Laboratory for Microanalytical Methods and Instrumentation, Key Laboratory of Bioorganic Phosphorus Chemistry and Chemical Biology (Ministry of Education), Tsinghua University, Beijing 100084, People\u2019s Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yanping","family":"Sun","sequence":"additional","affiliation":[{"name":"School of Chemistry and Biological Engineering, University of Science and Technology Beijing, Beijing 100083, People\u2019s Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shuyuan","family":"Zhang","sequence":"additional","affiliation":[{"name":"School of Chemistry and Biological Engineering, University of Science and Technology Beijing, Beijing 100083, People\u2019s Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0633-4098","authenticated-orcid":true,"given":"Aijun","family":"Tong","sequence":"additional","affiliation":[{"name":"Department of Chemistry, Beijing Key Laboratory for Microanalytical Methods and Instrumentation, Key Laboratory of Bioorganic Phosphorus Chemistry and Chemical Biology (Ministry of Education), Tsinghua University, Beijing 100084, People\u2019s Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5593-5773","authenticated-orcid":true,"given":"Yu","family":"Xiang","sequence":"additional","affiliation":[{"name":"Department of Chemistry, Beijing Key Laboratory for Microanalytical Methods and Instrumentation, Key Laboratory of Bioorganic Phosphorus Chemistry and Chemical Biology (Ministry of Education), Tsinghua University, Beijing 100084, People\u2019s Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2019,4,24]]},"reference":[{"key":"ref1\/cit1","doi-asserted-by":"publisher","DOI":"10.1016\/j.copbio.2005.10.006"},{"key":"ref2\/cit2","doi-asserted-by":"publisher","DOI":"10.1016\/j.chembiol.2009.01.008"},{"key":"ref3\/cit3","doi-asserted-by":"publisher","DOI":"10.1016\/j.tibs.2016.04.010"},{"key":"ref4\/cit4","doi-asserted-by":"publisher","DOI":"10.1021\/acs.accounts.7b00582"},{"key":"ref5\/cit5","doi-asserted-by":"publisher","DOI":"10.1038\/355564a0"},{"key":"ref6\/cit6","doi-asserted-by":"publisher","DOI":"10.1016\/S0959-440X(94)90227-5"},{"key":"ref7\/cit7","doi-asserted-by":"publisher","DOI":"10.1038\/nbt0597-427"},{"key":"ref8\/cit8","doi-asserted-by":"publisher","DOI":"10.1006\/jmbi.1997.1036"},{"key":"ref9\/cit9","doi-asserted-by":"publisher","DOI":"10.1007\/s00239-001-0066-1"},{"key":"ref10\/cit10","doi-asserted-by":"publisher","DOI":"10.1016\/1074-5521(94)90014-0"},{"key":"ref11\/cit11","doi-asserted-by":"publisher","DOI":"10.1016\/S1074-5521(96)90170-2"},{"key":"ref12\/cit12","doi-asserted-by":"publisher","DOI":"10.1038\/375611a0"},{"key":"ref13\/cit13","doi-asserted-by":"publisher","DOI":"10.1021\/ja028774y"},{"key":"ref14\/cit14","doi-asserted-by":"publisher","DOI":"10.1016\/S1074-5521(98)90006-0"},{"key":"ref15\/cit15","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.96.6.2746"},{"key":"ref16\/cit16","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1221946110"},{"key":"ref17\/cit17","doi-asserted-by":"publisher","DOI":"10.1021\/ja407586u"},{"key":"ref18\/cit18","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0305943101"},{"key":"ref19\/cit19","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/28.2.481"},{"key":"ref20\/cit20","doi-asserted-by":"publisher","DOI":"10.1021\/ja993688s"},{"key":"ref21\/cit21","doi-asserted-by":"publisher","DOI":"10.1016\/1074-5521(95)90028-4"},{"key":"ref22\/cit22","doi-asserted-by":"publisher","DOI":"10.1021\/ja0021316"},{"key":"ref23\/cit23","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0607875104"},{"key":"ref24\/cit24","doi-asserted-by":"publisher","DOI":"10.1002\/anie.200800960"},{"key":"ref25\/cit25","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1420361112"},{"key":"ref26\/cit26","doi-asserted-by":"publisher","DOI":"10.1016\/S1074-5521(02)00127-8"},{"key":"ref27\/cit27","doi-asserted-by":"publisher","DOI":"10.1021\/acs.analchem.6b00327"},{"key":"ref28\/cit28","doi-asserted-by":"publisher","DOI":"10.1021\/ac403762s"},{"key":"ref29\/cit29","doi-asserted-by":"publisher","DOI":"10.1016\/j.cbpa.2006.04.003"},{"key":"ref30\/cit30","doi-asserted-by":"publisher","DOI":"10.1039\/b718428j"},{"key":"ref31\/cit31","doi-asserted-by":"publisher","DOI":"10.1021\/cr030183i"},{"key":"ref32\/cit32","doi-asserted-by":"publisher","DOI":"10.1021\/ar900245u"},{"key":"ref33\/cit33","doi-asserted-by":"publisher","DOI":"10.1002\/asia.201000870"},{"key":"ref34\/cit34","doi-asserted-by":"publisher","DOI":"10.1039\/C3CS60264H"},{"key":"ref35\/cit35","doi-asserted-by":"publisher","DOI":"10.1039\/C4CC06855F"},{"key":"ref36\/cit36","doi-asserted-by":"publisher","DOI":"10.1039\/C5CS00586H"},{"key":"ref37\/cit37","doi-asserted-by":"publisher","DOI":"10.1021\/acs.chemrev.7b00063"},{"key":"ref38\/cit38","doi-asserted-by":"publisher","DOI":"10.1039\/b911431a"},{"key":"ref39\/cit39","doi-asserted-by":"publisher","DOI":"10.1021\/acs.analchem.7b04926"},{"key":"ref40\/cit40","doi-asserted-by":"publisher","DOI":"10.1002\/cbic.200800632"},{"key":"ref41\/cit41","doi-asserted-by":"publisher","DOI":"10.1023\/A:1026031224658"},{"key":"ref42\/cit42","first-page":"239","volume":"36","author":"Winde F.","year":"2010","journal-title":"Water SA"},{"key":"ref43\/cit43","doi-asserted-by":"publisher","DOI":"10.1021\/ja803607z"},{"key":"ref44\/cit44","doi-asserted-by":"publisher","DOI":"10.1021\/nl803887y"},{"key":"ref45\/cit45","doi-asserted-by":"publisher","DOI":"10.1038\/nchem.1092"},{"key":"ref46\/cit46","doi-asserted-by":"publisher","DOI":"10.1039\/c3an01182h"},{"key":"ref47\/cit47","doi-asserted-by":"publisher","DOI":"10.1016\/j.bios.2015.05.032"},{"key":"ref48\/cit48","doi-asserted-by":"publisher","DOI":"10.1038\/srep19646"},{"key":"ref49\/cit49","doi-asserted-by":"publisher","DOI":"10.1016\/j.bios.2016.05.008"},{"key":"ref50\/cit50","doi-asserted-by":"publisher","DOI":"10.1016\/j.bios.2015.11.024"},{"key":"ref51\/cit51","doi-asserted-by":"crossref","first-page":"389","DOI":"10.1007\/978-1-4939-6848-0_24","volume-title":"Biosensors and Biodetection: Methods and Protocols .","volume":"1","author":"Mazumdar D.","year":"2017","edition":"2"},{"key":"ref52\/cit52","doi-asserted-by":"publisher","DOI":"10.1007\/s00604-017-2472-0"},{"key":"ref53\/cit53","doi-asserted-by":"publisher","DOI":"10.1016\/j.aca.2016.12.021"},{"key":"ref54\/cit54","doi-asserted-by":"publisher","DOI":"10.3389\/fchem.2018.00332"},{"key":"ref55\/cit55","doi-asserted-by":"publisher","DOI":"10.1021\/ja400150v"},{"key":"ref56\/cit56","doi-asserted-by":"publisher","DOI":"10.1016\/j.copbio.2017.03.002"},{"key":"ref57\/cit57","doi-asserted-by":"publisher","DOI":"10.3390\/catal8110550"},{"key":"ref58\/cit58","doi-asserted-by":"publisher","DOI":"10.1021\/ja0276220"},{"key":"ref59\/cit59","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkg378"},{"key":"ref60\/cit60","doi-asserted-by":"publisher","DOI":"10.1016\/j.bmcl.2010.07.027"},{"key":"ref61\/cit61","doi-asserted-by":"publisher","DOI":"10.1039\/B611078A"},{"key":"ref62\/cit62","doi-asserted-by":"publisher","DOI":"10.1039\/c1ob05065f"},{"key":"ref63\/cit63","doi-asserted-by":"publisher","DOI":"10.1089\/nat.2012.0365"},{"key":"ref64\/cit64","doi-asserted-by":"publisher","DOI":"10.1016\/j.bmc.2014.05.070"},{"key":"ref65\/cit65","doi-asserted-by":"publisher","DOI":"10.1039\/C6OB00390G"},{"key":"ref66\/cit66","doi-asserted-by":"publisher","DOI":"10.1002\/chem.201504797"},{"key":"ref67\/cit67","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkw634"},{"key":"ref68\/cit68","doi-asserted-by":"publisher","DOI":"10.1039\/c2cc32919k"},{"key":"ref69\/cit69","doi-asserted-by":"publisher","DOI":"10.1039\/C4BM00256C"},{"key":"ref70\/cit70","doi-asserted-by":"publisher","DOI":"10.1021\/acs.bioconjchem.5b00608"},{"key":"ref71\/cit71","doi-asserted-by":"publisher","DOI":"10.1002\/chem.201100352"},{"key":"ref72\/cit72","doi-asserted-by":"publisher","DOI":"10.1016\/j.ica.2016.04.017"},{"key":"ref73\/cit73","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkt694"},{"key":"ref74\/cit74","doi-asserted-by":"crossref","first-page":"1262","DOI":"10.1002\/asia.200900660","volume":"5","author":"Li B. L.","year":"2010","journal-title":"Chem.\u2014Asian J."},{"key":"ref75\/cit75","doi-asserted-by":"publisher","DOI":"10.1021\/ar300011g"},{"key":"ref76\/cit76","doi-asserted-by":"publisher","DOI":"10.1021\/ac100244h"},{"key":"ref77\/cit77","doi-asserted-by":"publisher","DOI":"10.1021\/ja01197a048"},{"key":"ref78\/cit78","doi-asserted-by":"publisher","DOI":"10.1021\/ja992956j"},{"key":"ref79\/cit79","doi-asserted-by":"publisher","DOI":"10.1021\/ja029786m"},{"key":"ref80\/cit80","doi-asserted-by":"publisher","DOI":"10.1021\/ja905854a"},{"key":"ref81\/cit81","doi-asserted-by":"publisher","DOI":"10.1039\/b908345f"},{"key":"ref82\/cit82","doi-asserted-by":"publisher","DOI":"10.1039\/C4CC06170E"}],"container-title":["Analytical Chemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acs.analchem.9b00490","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,7,17]],"date-time":"2024-07-17T06:50:33Z","timestamp":1721199033000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/acs.analchem.9b00490"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,4,24]]},"references-count":82,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2019,5,21]]}},"alternative-id":["10.1021\/acs.analchem.9b00490"],"URL":"https:\/\/doi.org\/10.1021\/acs.analchem.9b00490","relation":{},"ISSN":["0003-2700","1520-6882"],"issn-type":[{"value":"0003-2700","type":"print"},{"value":"1520-6882","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,4,24]]}}}