{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,3]],"date-time":"2026-06-03T22:57:37Z","timestamp":1780527457320,"version":"3.54.1"},"reference-count":47,"publisher":"American Chemical Society (ACS)","issue":"29","license":[{"start":{"date-parts":[[2021,7,19]],"date-time":"2021-07-19T00:00:00Z","timestamp":1626652800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2021,7,19]],"date-time":"2021-07-19T00:00:00Z","timestamp":1626652800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2021,7,19]],"date-time":"2021-07-19T00:00:00Z","timestamp":1626652800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-045"}],"funder":[{"DOI":"10.13039\/100000055","name":"National Institute on Deafness and Other Communication Disorders","doi-asserted-by":"publisher","award":["R15DC016462"],"award-info":[{"award-number":["R15DC016462"]}],"id":[{"id":"10.13039\/100000055","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100013085","name":"Barnard College","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100013085","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100011756","name":"Sherman Fairchild Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100011756","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Biochemistry"],"published-print":{"date-parts":[[2021,7,27]]},"DOI":"10.1021\/acs.biochem.1c00170","type":"journal-article","created":{"date-parts":[[2021,7,19]],"date-time":"2021-07-19T12:00:28Z","timestamp":1626696028000},"page":"2320-2329","source":"Crossref","is-referenced-by-count":16,"title":["Variable Autoinhibition among Deafness-Associated Variants of Diaphanous 1 (DIAPH1)"],"prefix":"10.1021","volume":"60","author":[{"given":"Rabina","family":"Lakha","sequence":"first","affiliation":[{"name":"Department of Chemistry, Barnard College, New York, New York 10027, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Angela M.","family":"Montero","sequence":"additional","affiliation":[{"name":"Department of Chemistry, Barnard College, New York, New York 10027, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tayyaba","family":"Jabeen","sequence":"additional","affiliation":[{"name":"Department of Chemistry, Barnard College, New York, New York 10027, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christina C.","family":"Costeas","sequence":"additional","affiliation":[{"name":"Department of Chemistry, Barnard College, New York, New York 10027, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jia","family":"Ma","sequence":"additional","affiliation":[{"name":"Department of Chemistry, Columbia University, New York, New York 10027, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0564-9776","authenticated-orcid":true,"given":"Christina L.","family":"Vizcarra","sequence":"additional","affiliation":[{"name":"Department of Chemistry, Barnard College, New York, New York 10027, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2021,7,19]]},"reference":[{"key":"ref1\/cit1","doi-asserted-by":"publisher","DOI":"10.1016\/j.heares.2018.12.012"},{"key":"ref2\/cit2","doi-asserted-by":"publisher","DOI":"10.1002\/bdrc.21098"},{"key":"ref3\/cit3","doi-asserted-by":"publisher","DOI":"10.1016\/j.joto.2016.01.003"},{"key":"ref4\/cit4","doi-asserted-by":"publisher","DOI":"10.1016\/j.heares.2011.12.003"},{"key":"ref5\/cit5","doi-asserted-by":"publisher","DOI":"10.1126\/science.278.5341.1315"},{"key":"ref6\/cit6","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.124.6.699"},{"key":"ref7\/cit7","doi-asserted-by":"publisher","DOI":"10.1016\/S0960-9822(03)00540-2"},{"key":"ref8\/cit8","doi-asserted-by":"publisher","DOI":"10.1091\/mbc.e11-07-0616"},{"key":"ref9\/cit9","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0012896"},{"key":"ref10\/cit10","doi-asserted-by":"publisher","DOI":"10.1021\/bi026520j"},{"key":"ref11\/cit11","doi-asserted-by":"publisher","DOI":"10.1038\/nature03251"},{"key":"ref12\/cit12","doi-asserted-by":"publisher","DOI":"10.1083\/jcb.200709029"},{"key":"ref13\/cit13","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M805634200"},{"key":"ref14\/cit14","doi-asserted-by":"publisher","DOI":"10.1038\/sj.emboj.7600879"},{"key":"ref15\/cit15","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M411605200"},{"key":"ref16\/cit16","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M510277200"},{"key":"ref17\/cit17","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1003027107"},{"key":"ref18\/cit18","doi-asserted-by":"publisher","DOI":"10.1523\/ENEURO.0295-16.2016"},{"key":"ref19\/cit19","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2015-10-675629"},{"key":"ref20\/cit20","doi-asserted-by":"publisher","DOI":"10.15252\/emmm.201606609"},{"key":"ref21\/cit21","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.a.38411"},{"key":"ref22\/cit22","doi-asserted-by":"publisher","DOI":"10.1266\/ggs.16-00041"},{"key":"ref23\/cit23","doi-asserted-by":"publisher","DOI":"10.1111\/cge.12915"},{"key":"ref24\/cit24","doi-asserted-by":"publisher","DOI":"10.1136\/jmedgenet-2019-106282"},{"key":"ref25\/cit25","doi-asserted-by":"publisher","DOI":"10.1182\/bloodadvances.2018020370"},{"key":"ref26\/cit26","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2014-03-564328"},{"key":"ref27\/cit27","doi-asserted-by":"publisher","DOI":"10.1038\/ejhg.2014.82"},{"key":"ref28\/cit28","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.a.37422"},{"key":"ref29\/cit29","doi-asserted-by":"publisher","DOI":"10.1158\/0008-5472.CAN-07-1467"},{"key":"ref30\/cit30","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M703243200"},{"key":"ref31\/cit31","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0405902101"},{"key":"ref32\/cit32","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M808587200"},{"key":"ref33\/cit33","doi-asserted-by":"publisher","DOI":"10.1007\/s12551-018-0468-6"},{"key":"ref34\/cit34","doi-asserted-by":"publisher","DOI":"10.1038\/s41419-020-02743-z"},{"key":"ref35\/cit35","doi-asserted-by":"publisher","DOI":"10.1091\/mbc.E19-08-0463"},{"key":"ref36\/cit36","doi-asserted-by":"publisher","DOI":"10.1021\/bi980093l"},{"key":"ref37\/cit37","doi-asserted-by":"publisher","DOI":"10.1091\/mbc.12.4.1161"},{"key":"ref38\/cit38","doi-asserted-by":"publisher","DOI":"10.1007\/978-1-59745-353-0_15"},{"key":"ref39\/cit39","doi-asserted-by":"publisher","DOI":"10.1007\/BF00712034"},{"key":"ref40\/cit40","doi-asserted-by":"publisher","DOI":"10.1016\/j.cub.2011.01.047"},{"key":"ref41\/cit41","doi-asserted-by":"publisher","DOI":"10.1007\/978-1-62703-538-5_16"},{"key":"ref42\/cit42","doi-asserted-by":"publisher","DOI":"10.1016\/j.ab.2016.02.007"},{"key":"ref43\/cit43","doi-asserted-by":"publisher","DOI":"10.1126\/science.252.5009.1162"},{"key":"ref44\/cit44","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1017010108"},{"key":"ref45\/cit45","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijporl.2020.109947"},{"key":"ref46\/cit46","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajhg.2018.08.006"},{"key":"ref47\/cit47","doi-asserted-by":"publisher","DOI":"10.1186\/1472-6815-14-9"}],"container-title":["Biochemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acs.biochem.1c00170","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,4,27]],"date-time":"2023-04-27T04:48:14Z","timestamp":1682570894000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/acs.biochem.1c00170"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,7,19]]},"references-count":47,"journal-issue":{"issue":"29","published-print":{"date-parts":[[2021,7,27]]}},"alternative-id":["10.1021\/acs.biochem.1c00170"],"URL":"https:\/\/doi.org\/10.1021\/acs.biochem.1c00170","relation":{"has-preprint":[{"id-type":"doi","id":"10.1101\/2021.03.10.434847","asserted-by":"object"}]},"ISSN":["0006-2960","1520-4995"],"issn-type":[{"value":"0006-2960","type":"print"},{"value":"1520-4995","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,7,19]]}}}