{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,29]],"date-time":"2026-05-29T21:14:04Z","timestamp":1780089244974,"version":"3.54.0"},"reference-count":37,"publisher":"American Chemical Society (ACS)","issue":"3","license":[{"start":{"date-parts":[[2023,1,19]],"date-time":"2023-01-19T00:00:00Z","timestamp":1674086400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2023,1,19]],"date-time":"2023-01-19T00:00:00Z","timestamp":1674086400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2023,1,19]],"date-time":"2023-01-19T00:00:00Z","timestamp":1674086400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-045"}],"funder":[{"DOI":"10.13039\/100000060","name":"National Institute of Allergy and Infectious Diseases","doi-asserted-by":"publisher","award":["AI090048"],"award-info":[{"award-number":["AI090048"]}],"id":[{"id":"10.13039\/100000060","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100005815","name":"Firland Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100005815","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100019888","name":"College of Pharmacy, University of Kentucky","doi-asserted-by":"crossref","id":[{"id":"10.13039\/100019888","id-type":"DOI","asserted-by":"crossref"}]},{"name":"Center for Chemical Genomics, University of Michigan"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Biochemistry"],"published-print":{"date-parts":[[2023,2,7]]},"DOI":"10.1021\/acs.biochem.2c00658","type":"journal-article","created":{"date-parts":[[2023,1,19]],"date-time":"2023-01-19T20:55:20Z","timestamp":1674161720000},"page":"710-721","source":"Crossref","is-referenced-by-count":8,"title":["Discovery and Mechanistic Analysis of Structurally Diverse Inhibitors of Acetyltransferase Eis among FDA-Approved Drugs"],"prefix":"10.1021","volume":"62","author":[{"given":"Allan H.","family":"Pang","sequence":"first","affiliation":[{"name":"Department of Pharmaceutical Sciences, College of Pharmacy, University of Kentucky, 789 South Limestone Street, Lexington, Kentucky40536-0596, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Keith D.","family":"Green","sequence":"additional","affiliation":[{"name":"Department of Pharmaceutical Sciences, College of Pharmacy, University of Kentucky, 789 South Limestone Street, Lexington, Kentucky40536-0596, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2845-5459","authenticated-orcid":true,"given":"Ankita","family":"Punetha","sequence":"additional","affiliation":[{"name":"Department of Pharmaceutical Sciences, College of Pharmacy, University of Kentucky, 789 South Limestone Street, Lexington, Kentucky40536-0596, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3605-169X","authenticated-orcid":true,"given":"Nishad","family":"Thamban Chandrika","sequence":"additional","affiliation":[{"name":"Department of Pharmaceutical Sciences, College of Pharmacy, University of Kentucky, 789 South Limestone Street, Lexington, Kentucky40536-0596, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kaitlind C.","family":"Howard","sequence":"additional","affiliation":[{"name":"Department of Pharmaceutical Sciences, College of Pharmacy, University of Kentucky, 789 South Limestone Street, Lexington, Kentucky40536-0596, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7961-5555","authenticated-orcid":true,"given":"Sylvie","family":"Garneau-Tsodikova","sequence":"additional","affiliation":[{"name":"Department of Pharmaceutical Sciences, College of Pharmacy, University of Kentucky, 789 South Limestone Street, Lexington, Kentucky40536-0596, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7094-4216","authenticated-orcid":true,"given":"Oleg V.","family":"Tsodikov","sequence":"additional","affiliation":[{"name":"Department of Pharmaceutical Sciences, College of Pharmacy, University of Kentucky, 789 South Limestone Street, Lexington, Kentucky40536-0596, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2023,1,19]]},"reference":[{"key":"ref1\/cit1","unstructured":"World Health\nOrganization Fact Sheet 2022 (Tuberculosis). https:\/\/www.who.int\/news-room\/fact-sheets\/detail\/tuberculosis."},{"key":"ref2\/cit2","doi-asserted-by":"publisher","DOI":"10.15585\/mmwr.mm7012a1"},{"key":"ref3\/cit3","doi-asserted-by":"publisher","DOI":"10.3201\/eid2610.202782"},{"key":"ref4\/cit4","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijtb.2015.11.001"},{"key":"ref5\/cit5","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1105379108"},{"key":"ref6\/cit6","doi-asserted-by":"publisher","DOI":"10.1021\/bi3004473"},{"key":"ref7\/cit7","doi-asserted-by":"publisher","DOI":"10.1002\/cbic.201300359"},{"key":"ref8\/cit8","doi-asserted-by":"publisher","DOI":"10.1021\/acs.biochem.5b00244"},{"key":"ref9\/cit9","doi-asserted-by":"publisher","DOI":"10.1021\/acsinfecdis.5b00036"},{"key":"ref10\/cit10","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/dks497"},{"key":"ref11\/cit11","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0907925106"},{"key":"ref12\/cit12","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.01550-10"},{"key":"ref13\/cit13","doi-asserted-by":"crossref","first-page":"1857","DOI":"10.1128\/AAC.02191-12","volume":"57","author":"Reeves A. Z.","year":"2013","journal-title":"Antimicrob. Agents Chemother."},{"key":"ref14\/cit14","doi-asserted-by":"publisher","DOI":"10.1002\/cmdc.201100332"},{"key":"ref15\/cit15","doi-asserted-by":"publisher","DOI":"10.1021\/acschembio.6b00110"},{"key":"ref16\/cit16","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jmedchem.6b01161"},{"key":"ref17\/cit17","doi-asserted-by":"publisher","DOI":"10.1021\/acsmedchemlett.6b00261"},{"key":"ref18\/cit18","doi-asserted-by":"publisher","DOI":"10.1021\/acsinfecdis.6b00193"},{"key":"ref19\/cit19","doi-asserted-by":"publisher","DOI":"10.1021\/acsinfecdis.8b00074"},{"key":"ref20\/cit20","doi-asserted-by":"publisher","DOI":"10.1021\/acschembio.0c00184"},{"key":"ref21\/cit21","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejmech.2022.114698"},{"key":"ref22\/cit22","doi-asserted-by":"publisher","DOI":"10.1039\/D1MD00239B"},{"key":"ref23\/cit23","doi-asserted-by":"publisher","DOI":"10.1038\/nrd1468"},{"key":"ref24\/cit24","doi-asserted-by":"publisher","DOI":"10.3332\/ecancer.2014.485"},{"key":"ref25\/cit25","doi-asserted-by":"publisher","DOI":"10.1021\/acsinfecdis.9b00228"},{"key":"ref26\/cit26","doi-asserted-by":"publisher","DOI":"10.1016\/S0076-6879(97)76066-X"},{"key":"ref27\/cit27","doi-asserted-by":"publisher","DOI":"10.1107\/S0021889807021206"},{"key":"ref28\/cit28","doi-asserted-by":"publisher","DOI":"10.1107\/S0907444904019158"},{"key":"ref29\/cit29","doi-asserted-by":"publisher","DOI":"10.1107\/S0907444996012255"},{"key":"ref30\/cit30","doi-asserted-by":"publisher","DOI":"10.1002\/pro.3330"},{"key":"ref31\/cit31","doi-asserted-by":"publisher","DOI":"10.1002\/cbic.200900584"},{"key":"ref32\/cit32","unstructured":"British National Formulary: BNF 76, 76th ed. Pharmaceutical Press, 2018; p 1169. 9780857113382."},{"key":"ref33\/cit33","doi-asserted-by":"publisher","DOI":"10.1177\/0960327111400104"},{"key":"ref34\/cit34","doi-asserted-by":"publisher","DOI":"10.1016\/j.vaccine.2006.05.097"},{"key":"ref35\/cit35","doi-asserted-by":"publisher","DOI":"10.1183\/13993003.00321-2015"},{"key":"ref36\/cit36","doi-asserted-by":"publisher","DOI":"10.1099\/mic.0.2006\/002642-0"},{"key":"ref37\/cit37","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejmech.2020.112175"}],"container-title":["Biochemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acs.biochem.2c00658","content-type":"application\/pdf","content-version":"vor","intended-application":"unspecified"},{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acs.biochem.2c00658","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,4,25]],"date-time":"2023-04-25T19:57:25Z","timestamp":1682452645000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/acs.biochem.2c00658"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,1,19]]},"references-count":37,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2023,2,7]]}},"alternative-id":["10.1021\/acs.biochem.2c00658"],"URL":"https:\/\/doi.org\/10.1021\/acs.biochem.2c00658","relation":{},"ISSN":["0006-2960","1520-4995"],"issn-type":[{"value":"0006-2960","type":"print"},{"value":"1520-4995","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,1,19]]}}}