{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,10]],"date-time":"2026-10-10T18:05:15Z","timestamp":1791655515799,"version":"4.3.4"},"reference-count":100,"publisher":"American Chemical Society (ACS)","issue":"4","license":[{"start":{"date-parts":[[2024,12,21]],"date-time":"2024-12-21T00:00:00Z","timestamp":1734739200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2024,12,21]],"date-time":"2024-12-21T00:00:00Z","timestamp":1734739200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2024,12,21]],"date-time":"2024-12-21T00:00:00Z","timestamp":1734739200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-045"}],"funder":[{"DOI":"10.13039\/501100001843","name":"Science and Engineering Research Board","doi-asserted-by":"publisher","award":["IPA\/2020\/000054"],"award-info":[{"award-number":["IPA\/2020\/000054"]}],"id":[{"id":"10.13039\/501100001843","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004541","name":"Ministry of Education, India","doi-asserted-by":"publisher","award":["STARS2\/2023-0209"],"award-info":[{"award-number":["STARS2\/2023-0209"]}],"id":[{"id":"10.13039\/501100004541","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Biochemistry"],"published-print":{"date-parts":[[2025,2,18]]},"DOI":"10.1021\/acs.biochem.4c00536","type":"journal-article","created":{"date-parts":[[2024,12,21]],"date-time":"2024-12-21T10:50:21Z","timestamp":1734778221000},"page":"823-840","source":"Crossref","is-referenced-by-count":12,"title":["Disruption of Molecular Interactions between the G3BP1 Stress Granule Host Protein and the Nucleocapsid (NTD-N) Protein Impedes SARS-CoV-2 Virus Replication"],"prefix":"10.1021","volume":"64","author":[{"given":"Preeti","family":"Dhaka","sequence":"first","affiliation":[{"name":"Department of Biosciences and Bioengineering","place":["Roorkee, India"]},{"name":"Indian Institute of Technology Roorkee","place":["Roorkee, India"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ankur","family":"Singh","sequence":"additional","affiliation":[{"name":"Department of Biosciences and Bioengineering","place":["Roorkee, India"]},{"name":"Indian Institute of Technology Roorkee","place":["Roorkee, India"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sanketkumar","family":"Nehul","sequence":"additional","affiliation":[{"name":"Department of Biosciences and Bioengineering","place":["Roorkee, India"]},{"name":"Indian Institute of Technology Roorkee","place":["Roorkee, India"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shweta","family":"Choudhary","sequence":"additional","affiliation":[{"name":"Department of Biosciences and Bioengineering","place":["Roorkee, India"]},{"name":"Indian Institute of Technology Roorkee","place":["Roorkee, India"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Prasan Kumar","family":"Panda","sequence":"additional","affiliation":[{"name":"Department of Medicine","place":["Rishikesh, India"]},{"name":"All India Institute of Medical Sciences (AIIMS)","place":["Rishikesh, India"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gaurav Kumar","family":"Sharma","sequence":"additional","affiliation":[{"name":"Indian Veterinary Research Institute, Izatnagar, Bareilly, Uttar Pradesh 243122, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2128-7736","authenticated-orcid":true,"given":"Pravindra","family":"Kumar","sequence":"additional","affiliation":[{"name":"Department of Biosciences and Bioengineering","place":["Roorkee, India"]},{"name":"Indian Institute of Technology Roorkee","place":["Roorkee, India"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1730-003X","authenticated-orcid":true,"given":"Shailly","family":"Tomar","sequence":"additional","affiliation":[{"name":"Department of Biosciences and Bioengineering","place":["Roorkee, India"]},{"name":"Indian Institute of Technology Roorkee","place":["Roorkee, India"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2024,12,21]]},"reference":[{"key":"ref1\/cit1","doi-asserted-by":"publisher","DOI":"10.1038\/nri.2017.63"},{"key":"ref2\/cit2","doi-asserted-by":"publisher","DOI":"10.1016\/j.it.2014.07.006"},{"key":"ref3\/cit3","doi-asserted-by":"publisher","DOI":"10.1016\/j.virol.2022.08.008"},{"key":"ref4\/cit4","doi-asserted-by":"publisher","DOI":"10.3389\/fviro.2022.959586"},{"key":"ref5\/cit5","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.00017-08"},{"key":"ref6\/cit6","doi-asserted-by":"publisher","DOI":"10.1371\/journal.ppat.1002433"},{"key":"ref7\/cit7","doi-asserted-by":"publisher","DOI":"10.1038\/nsmb.1680"},{"key":"ref8\/cit8","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.02472-07"},{"key":"ref9\/cit9","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.00195-11"},{"key":"ref10\/cit10","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.01546-09"},{"key":"ref11\/cit11","doi-asserted-by":"publisher","DOI":"10.1016\/j.isci.2021.103562"},{"key":"ref12\/cit12","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.03612-14"},{"key":"ref13\/cit13","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.01506-12"},{"key":"ref14\/cit14","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.00477-18"},{"key":"ref15\/cit15","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.00520-19"},{"key":"ref16\/cit16","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pntd.0005775"},{"key":"ref17\/cit17","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0703348104"},{"key":"ref18\/cit18","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.01606-16"},{"key":"ref19\/cit19","doi-asserted-by":"publisher","DOI":"10.1371\/journal.ppat.1004242"},{"key":"ref20\/cit20","doi-asserted-by":"publisher","DOI":"10.3892\/ijmm.2015.2169"},{"key":"ref21\/cit21","doi-asserted-by":"publisher","DOI":"10.1111\/j.1462-5822.2007.00951.x"},{"key":"ref22\/cit22","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.01634-06"},{"key":"ref23\/cit23","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.07101-11"},{"key":"ref24\/cit24","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.02418-10"},{"key":"ref25\/cit25","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.01517-07"},{"key":"ref26\/cit26","doi-asserted-by":"publisher","DOI":"10.1091\/mbc.e12-08-0619"},{"key":"ref27\/cit27","doi-asserted-by":"publisher","DOI":"10.1371\/journal.ppat.1004659"},{"key":"ref28\/cit28","doi-asserted-by":"publisher","DOI":"10.1091\/mbc.e05-02-0124"},{"key":"ref29\/cit29","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.01011-08"},{"key":"ref30\/cit30","doi-asserted-by":"publisher","DOI":"10.1186\/1476-4598-9-37"},{"key":"ref31\/cit31","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.01983-09"},{"key":"ref32\/cit32","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.80.8.4122-4134.2006"},{"key":"ref33\/cit33","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.03248-12"},{"key":"ref34\/cit34","doi-asserted-by":"publisher","DOI":"10.1186\/1475-2867-10-12"},{"key":"ref35\/cit35","doi-asserted-by":"publisher","DOI":"10.1016\/j.virol.2013.10.009"},{"key":"ref36\/cit36","doi-asserted-by":"publisher","DOI":"10.1016\/j.chom.2007.08.006"},{"key":"ref37\/cit37","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.01320-09"},{"key":"ref38\/cit38","doi-asserted-by":"publisher","DOI":"10.1159\/000503030"},{"key":"ref39\/cit39","doi-asserted-by":"publisher","DOI":"10.1083\/jcb.201609081"},{"key":"ref40\/cit40","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2020.03.046"},{"key":"ref41\/cit41","doi-asserted-by":"publisher","DOI":"10.1038\/s41421-021-00275-0"},{"key":"ref42\/cit42","doi-asserted-by":"publisher","DOI":"10.1016\/j.virol.2019.01.007"},{"key":"ref43\/cit43","doi-asserted-by":"publisher","DOI":"10.1128\/mBio.02486-14"},{"key":"ref44\/cit44","doi-asserted-by":"publisher","DOI":"10.3390\/pathogens10111459"},{"key":"ref45\/cit45","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-021-26498-z"},{"key":"ref46\/cit46","doi-asserted-by":"publisher","DOI":"10.1096\/fj.202001351"},{"key":"ref47\/cit47","doi-asserted-by":"publisher","DOI":"10.3389\/fmicb.2023.1138864"},{"key":"ref48\/cit48","doi-asserted-by":"publisher","DOI":"10.1038\/s41587-022-01474-0"},{"key":"ref49\/cit49","doi-asserted-by":"publisher","DOI":"10.15252\/msb.202110396"},{"key":"ref50\/cit50","doi-asserted-by":"publisher","DOI":"10.1016\/j.jmb.2022.167516"},{"key":"ref51\/cit51","doi-asserted-by":"publisher","DOI":"10.1038\/s41586-021-03493-4"},{"key":"ref52\/cit52","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-024-44958-0"},{"key":"ref53\/cit53","doi-asserted-by":"publisher","DOI":"10.1098\/rsob.160078"},{"key":"ref54\/cit54","doi-asserted-by":"publisher","unstructured":"Mahajan, S.; Kumar, R.; Singh, A.; Pareek, A.; Long, S.; McInerney, G.; Tomar, S.Targeting host protein G3BP1 for the discovery of novel antiviral inhibitors against the Chikungunya virus\n                      bioRxiv\n                      2022 10.1101\/2022.11.11.516135.","DOI":"10.1101\/2022.11.11.516135"},{"key":"ref55\/cit55","doi-asserted-by":"publisher","DOI":"10.1038\/s41392-020-00315-3"},{"key":"ref56\/cit56","doi-asserted-by":"publisher","DOI":"10.1016\/j.apsb.2023.07.016"},{"key":"ref57\/cit57","doi-asserted-by":"publisher","DOI":"10.1038\/s41586-020-2008-3"},{"key":"ref58\/cit58","doi-asserted-by":"publisher","DOI":"10.3389\/fmolb.2020.605236"},{"key":"ref59\/cit59","doi-asserted-by":"publisher","DOI":"10.3390\/vaccines10040608"},{"key":"ref60\/cit60","doi-asserted-by":"publisher","DOI":"10.1038\/s41577-022-00762-9"},{"key":"ref61\/cit61","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijbiomac.2021.02.071"},{"key":"ref62\/cit62","doi-asserted-by":"publisher","DOI":"10.1128\/spectrum.01186-23"},{"key":"ref63\/cit63","doi-asserted-by":"publisher","DOI":"10.1128\/CMR.00168-19"},{"key":"ref64\/cit64","doi-asserted-by":"publisher","DOI":"10.1038\/s41586-020-2286-9"},{"key":"ref65\/cit65","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2020.01664"},{"key":"ref66\/cit66","doi-asserted-by":"publisher","DOI":"10.1016\/j.csbj.2020.08.006"},{"key":"ref67\/cit67","doi-asserted-by":"publisher","DOI":"10.1016\/j.antiviral.2020.104808"},{"key":"ref68\/cit68","doi-asserted-by":"publisher","DOI":"10.1016\/j.celrep.2024.113965"},{"key":"ref69\/cit69","doi-asserted-by":"publisher","DOI":"10.1016\/j.jmb.2007.02.069"},{"key":"ref70\/cit70","doi-asserted-by":"publisher","DOI":"10.1016\/j.abb.2023.109820"},{"key":"ref71\/cit71","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkac1179"},{"key":"ref72\/cit72","doi-asserted-by":"publisher","DOI":"10.1128\/jvi.00412-22"},{"key":"ref73\/cit73","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.02011-09"},{"key":"ref74\/cit74","doi-asserted-by":"publisher","DOI":"10.1038\/s41392-021-00742-w"},{"key":"ref75\/cit75","doi-asserted-by":"publisher","DOI":"10.1016\/j.virol.2017.12.020"},{"key":"ref76\/cit76","doi-asserted-by":"publisher","DOI":"10.1016\/j.apsb.2020.04.009"},{"key":"ref77\/cit77","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0080947"},{"key":"ref78\/cit78","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/28.1.235"},{"key":"ref79\/cit79","doi-asserted-by":"publisher","DOI":"10.3389\/fmolb.2021.729513"},{"key":"ref80\/cit80","doi-asserted-by":"publisher","DOI":"10.1002\/jcc.21334"},{"key":"ref81\/cit81","first-page":"82","volume":"40","author":"Delano W. L.","year":"2002","journal-title":"CCP4 Newsl. Protein Crystallogr."},{"key":"ref82\/cit82","doi-asserted-by":"publisher","DOI":"10.1016\/j.antiviral.2017.08.015"},{"key":"ref83\/cit83","doi-asserted-by":"publisher","DOI":"10.1002\/prot.20955"},{"key":"ref84\/cit84","doi-asserted-by":"publisher","DOI":"10.1016\/j.jsb.2023.108034"},{"key":"ref85\/cit85","series-title":"Methods in Molecular Biology","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1007\/978-1-4939-2425-7_11","volume-title":"Protein-Protein InteractionsMethods and Applications","volume":"1278","author":"Velazquez-Campoy A.","year":"2015","edition":"2"},{"key":"ref86\/cit86","doi-asserted-by":"publisher","DOI":"10.1007\/978-1-0716-1197-5_5"},{"key":"ref87\/cit87","doi-asserted-by":"publisher","DOI":"10.1007\/s00249-021-01509-5"},{"key":"ref88\/cit88","doi-asserted-by":"publisher","DOI":"10.1016\/j.ab.2019.01.010"},{"key":"ref89\/cit89","doi-asserted-by":"publisher","DOI":"10.1038\/ja.2013.106"},{"key":"ref90\/cit90","doi-asserted-by":"publisher","DOI":"10.1177\/2472555217712001"},{"key":"ref91\/cit91","doi-asserted-by":"publisher","DOI":"10.1021\/ci960402j"},{"key":"ref92\/cit92","doi-asserted-by":"publisher","DOI":"10.1016\/j.biochi.2018.04.004"},{"key":"ref93\/cit93","doi-asserted-by":"publisher","DOI":"10.1016\/j.virol.2021.05.013"},{"key":"ref94\/cit94","doi-asserted-by":"publisher","DOI":"10.1002\/iub.2793"},{"key":"ref95\/cit95","doi-asserted-by":"publisher","DOI":"10.1128\/mbio.02388-23"},{"key":"ref96\/cit96","doi-asserted-by":"publisher","DOI":"10.1038\/s41419-018-0504-2"},{"key":"ref97\/cit97","doi-asserted-by":"publisher","DOI":"10.3390\/v15020449"},{"key":"ref98\/cit98","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2021.718548"},{"key":"ref99\/cit99","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0132072"},{"key":"ref100\/cit100","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.01218-20"}],"container-title":["Biochemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acs.biochem.4c00536","content-type":"application\/pdf","content-version":"vor","intended-application":"unspecified"},{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acs.biochem.4c00536","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,2,18]],"date-time":"2025-02-18T04:10:46Z","timestamp":1739851846000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/acs.biochem.4c00536"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,12,21]]},"references-count":100,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2025,2,18]]}},"alternative-id":["10.1021\/acs.biochem.4c00536"],"URL":"https:\/\/doi.org\/10.1021\/acs.biochem.4c00536","relation":{"has-preprint":[{"id-type":"doi","id":"10.1101\/2024.10.27.620470","asserted-by":"object"}]},"ISSN":["0006-2960","1520-4995"],"issn-type":[{"value":"0006-2960","type":"print"},{"value":"1520-4995","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,12,21]]}}}