{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,2]],"date-time":"2026-04-02T02:32:00Z","timestamp":1775097120877,"version":"3.50.1"},"reference-count":94,"publisher":"American Chemical Society (ACS)","issue":"5","license":[{"start":{"date-parts":[[2025,2,17]],"date-time":"2025-02-17T00:00:00Z","timestamp":1739750400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100009252","name":"Hamilton College","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100009252","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000057","name":"National Institute of General Medical Sciences","doi-asserted-by":"publisher","award":["GM127079"],"award-info":[{"award-number":["GM127079"]}],"id":[{"id":"10.13039\/100000057","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000057","name":"National Institute of General Medical Sciences","doi-asserted-by":"publisher","award":["GM141284"],"award-info":[{"award-number":["GM141284"]}],"id":[{"id":"10.13039\/100000057","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000057","name":"National Institute of General Medical Sciences","doi-asserted-by":"publisher","award":["GM55365"],"award-info":[{"award-number":["GM55365"]}],"id":[{"id":"10.13039\/100000057","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Biochemistry"],"published-print":{"date-parts":[[2025,3,4]]},"DOI":"10.1021\/acs.biochem.4c00692","type":"journal-article","created":{"date-parts":[[2025,2,17]],"date-time":"2025-02-17T17:16:36Z","timestamp":1739812596000},"page":"1157-1167","source":"Crossref","is-referenced-by-count":3,"title":["Structural Elucidation of the Reduced Mn(III)\/Fe(III) Intermediate of the Radical-Initiating Metallocofactor in <i>Chlamydia trachomatis<\/i> Ribonucleotide Reductase"],"prefix":"10.1021","volume":"64","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1257-2850","authenticated-orcid":true,"given":"Ryan J.","family":"Martinie","sequence":"first","affiliation":[{"name":"Department of Chemistry","place":["Clinton, United States"]},{"name":"Hamilton College","place":["Clinton, United States"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jovan","family":"Livada","sequence":"additional","affiliation":[{"name":"Department of Chemistry","place":["University Park, United States"]},{"name":"The Pennsylvania State University","place":["University Park, United States"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nyaari","family":"Kothiya","sequence":"additional","affiliation":[{"name":"Department of Chemistry","place":["Clinton, United States"]},{"name":"Hamilton College","place":["Clinton, United States"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0751-8585","authenticated-orcid":true,"suffix":"Jr.","given":"J. Martin","family":"Bollinger","sequence":"additional","affiliation":[{"name":"Department of Chemistry","place":["University Park, United States"]},{"name":"The Pennsylvania State University","place":["University Park, United States"]},{"name":"Department of Biochemistry and Molecular Biology","place":["University Park, United States"]},{"name":"The Pennsylvania State University","place":["University Park, United States"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3302-7053","authenticated-orcid":true,"given":"Carsten","family":"Krebs","sequence":"additional","affiliation":[{"name":"Department of Chemistry","place":["University Park, United States"]},{"name":"The Pennsylvania State University","place":["University Park, United States"]},{"name":"Department of Biochemistry and Molecular Biology","place":["University Park, United States"]},{"name":"The Pennsylvania State University","place":["University Park, United States"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9285-1253","authenticated-orcid":true,"given":"Alexey","family":"Silakov","sequence":"additional","affiliation":[{"name":"Department of Chemistry","place":["University Park, United States"]},{"name":"The Pennsylvania State University","place":["University Park, United States"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"316","published-online":{"date-parts":[[2025,2,17]]},"reference":[{"key":"ref1\/cit1","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.biochem.75.103004.142443"},{"key":"ref2\/cit2","doi-asserted-by":"publisher","DOI":"10.1146\/annurev-biochem-061408-095817"},{"key":"ref3\/cit3","doi-asserted-by":"publisher","DOI":"10.1146\/annurev-biochem-013118-111843"},{"key":"ref4\/cit4","doi-asserted-by":"publisher","DOI":"10.1021\/cr9400875"},{"key":"ref5\/cit5","doi-asserted-by":"publisher","DOI":"10.1021\/bi00155a029"},{"key":"ref6\/cit6","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9258(19)70598-5"},{"key":"ref7\/cit7","doi-asserted-by":"publisher","DOI":"10.1126\/science.271.5248.477"},{"key":"ref8\/cit8","doi-asserted-by":"publisher","DOI":"10.1021\/cr020421u"},{"key":"ref9\/cit9","doi-asserted-by":"publisher","DOI":"10.1021\/ar4000407"},{"key":"ref10\/cit10","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1220691110"},{"key":"ref11\/cit11","doi-asserted-by":"publisher","DOI":"10.1126\/science.aba6794"},{"key":"ref12\/cit12","doi-asserted-by":"publisher","DOI":"10.1021\/bi00725a005"},{"key":"ref13\/cit13","doi-asserted-by":"publisher","DOI":"10.1038\/nsb774"},{"key":"ref14\/cit14","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.271.12.6827"},{"key":"ref15\/cit15","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.271.34.20770"},{"key":"ref16\/cit16","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.272.39.24216"},{"key":"ref17\/cit17","doi-asserted-by":"publisher","DOI":"10.1016\/B978-0-12-409547-2.14865-6"},{"key":"ref18\/cit18","doi-asserted-by":"publisher","DOI":"10.1016\/j.jbc.2021.101137"},{"key":"ref19\/cit19","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9258(19)45166-1"},{"key":"ref20\/cit20","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9258(19)43313-9"},{"key":"ref21\/cit21","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9258(17)32750-3"},{"key":"ref22\/cit22","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9258(17)37999-1"},{"key":"ref23\/cit23","doi-asserted-by":"publisher","DOI":"10.1002\/j.1460-2075.1986.tb04461.x"},{"key":"ref24\/cit24","doi-asserted-by":"publisher","DOI":"10.1021\/ja401342s"},{"key":"ref25\/cit25","doi-asserted-by":"publisher","DOI":"10.1126\/science.1141179"},{"key":"ref26\/cit26","doi-asserted-by":"publisher","DOI":"10.1021\/acs.biochem.8b00247"},{"key":"ref27\/cit27","doi-asserted-by":"publisher","DOI":"10.1126\/science.1098419"},{"key":"ref28\/cit28","doi-asserted-by":"publisher","DOI":"10.1021\/ja072528a"},{"key":"ref29\/cit29","doi-asserted-by":"publisher","DOI":"10.1016\/j.febslet.2007.06.023"},{"key":"ref30\/cit30","doi-asserted-by":"publisher","DOI":"10.1021\/bi8017625"},{"key":"ref31\/cit31","doi-asserted-by":"publisher","DOI":"10.1016\/j.sbi.2008.11.007"},{"key":"ref32\/cit32","doi-asserted-by":"publisher","DOI":"10.1021\/bi400819x"},{"key":"ref33\/cit33","doi-asserted-by":"publisher","DOI":"10.1002\/jcc.20084"},{"key":"ref34\/cit34","doi-asserted-by":"publisher","DOI":"10.1021\/ja00067a086"},{"key":"ref35\/cit35","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9258(20)80579-1"},{"key":"ref36\/cit36","doi-asserted-by":"publisher","DOI":"10.1126\/science.275.5299.515"},{"key":"ref37\/cit37","doi-asserted-by":"publisher","DOI":"10.1038\/nature14160"},{"key":"ref38\/cit38","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.7b09560"},{"key":"ref39\/cit39","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.8b10313"},{"key":"ref40\/cit40","doi-asserted-by":"publisher","DOI":"10.1021\/ja9718230"},{"key":"ref41\/cit41","doi-asserted-by":"publisher","DOI":"10.1021\/ja407438p"},{"key":"ref42\/cit42","doi-asserted-by":"publisher","DOI":"10.1021\/ja070909i"},{"key":"ref43\/cit43","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.5b10763"},{"key":"ref44\/cit44","doi-asserted-by":"publisher","DOI":"10.1126\/science.1650033"},{"key":"ref45\/cit45","doi-asserted-by":"publisher","DOI":"10.1021\/ja960399k"},{"key":"ref46\/cit46","doi-asserted-by":"publisher","DOI":"10.1021\/ja952651e"},{"key":"ref47\/cit47","doi-asserted-by":"publisher","DOI":"10.1021\/ja9709942"},{"key":"ref48\/cit48","doi-asserted-by":"publisher","DOI":"10.1021\/ja9824270"},{"key":"ref49\/cit49","doi-asserted-by":"publisher","DOI":"10.1021\/ja809223s"},{"key":"ref50\/cit50","doi-asserted-by":"publisher","DOI":"10.1021\/ja036556e"},{"key":"ref51\/cit51","doi-asserted-by":"publisher","DOI":"10.1038\/370533a0"},{"key":"ref52\/cit52","doi-asserted-by":"publisher","DOI":"10.1021\/ja054991y"},{"key":"ref53\/cit53","doi-asserted-by":"publisher","DOI":"10.1021\/ja076459b"},{"key":"ref54\/cit54","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1112715108"},{"key":"ref55\/cit55","doi-asserted-by":"publisher","DOI":"10.1021\/bi034374r"},{"key":"ref56\/cit56","doi-asserted-by":"publisher","DOI":"10.1021\/ja055927j"},{"key":"ref57\/cit57","doi-asserted-by":"publisher","DOI":"10.1021\/ja057776q"},{"key":"ref58\/cit58","doi-asserted-by":"publisher","DOI":"10.1021\/ja076043y"},{"key":"ref59\/cit59","doi-asserted-by":"publisher","DOI":"10.1021\/ja1069344"},{"key":"ref60\/cit60","doi-asserted-by":"publisher","DOI":"10.1021\/ja201640n"},{"key":"ref61\/cit61","doi-asserted-by":"publisher","DOI":"10.1021\/ja510513z"},{"key":"ref62\/cit62","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.7b08192"},{"key":"ref63\/cit63","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.1c01359"},{"key":"ref64\/cit64","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.2c11483"},{"key":"ref65\/cit65","doi-asserted-by":"publisher","DOI":"10.1021\/ja211314p"},{"key":"ref66\/cit66","doi-asserted-by":"publisher","DOI":"10.1021\/bi700906g"},{"key":"ref67\/cit67","doi-asserted-by":"publisher","DOI":"10.1021\/bi800881m"},{"key":"ref68\/cit68","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.6b11563"},{"key":"ref69\/cit69","doi-asserted-by":"publisher","DOI":"10.1002\/anie.201807366"},{"key":"ref70\/cit70","doi-asserted-by":"publisher","DOI":"10.1021\/ja804365e"},{"key":"ref71\/cit71","doi-asserted-by":"publisher","DOI":"10.1021\/ja409510d"},{"key":"ref72\/cit72","doi-asserted-by":"publisher","DOI":"10.1021\/ja00140a003"},{"key":"ref73\/cit73","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jpcb.5b04067"},{"key":"ref74\/cit74","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0812971106"},{"key":"ref75\/cit75","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1304368110"},{"key":"ref76\/cit76","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.3c03419"},{"key":"ref77\/cit77","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.3c12131"},{"key":"ref78\/cit78","doi-asserted-by":"publisher","DOI":"10.1021\/ja507435t"},{"key":"ref79\/cit79","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M115.675223"},{"key":"ref80\/cit80","doi-asserted-by":"publisher","DOI":"10.1021\/acs.biochem.7b00403"},{"key":"ref81\/cit81","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.RA119.010570"},{"key":"ref82\/cit82","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.0c00333"},{"key":"ref83\/cit83","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.1c13738"},{"key":"ref84\/cit84","doi-asserted-by":"publisher","DOI":"10.1021\/bi100037b"},{"key":"ref85\/cit85","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jpcb.5b04614"},{"key":"ref86\/cit86","doi-asserted-by":"publisher","DOI":"10.1021\/ja073179n"},{"key":"ref87\/cit87","doi-asserted-by":"publisher","DOI":"10.1021\/acs.inorgchem.1c00684"},{"key":"ref88\/cit88","doi-asserted-by":"publisher","DOI":"10.1016\/j.jinorgbio.2016.04.019"},{"key":"ref89\/cit89","doi-asserted-by":"publisher","DOI":"10.1016\/S0009-2614(97)00293-5"},{"key":"ref90\/cit90","doi-asserted-by":"publisher","DOI":"10.1021\/ic902051t"},{"key":"ref91\/cit91","doi-asserted-by":"publisher","DOI":"10.1021\/bi030011f"},{"key":"ref92\/cit92","doi-asserted-by":"publisher","DOI":"10.1109\/TMTT.2009.2015028"},{"key":"ref93\/cit93","doi-asserted-by":"publisher","DOI":"10.1016\/j.jmr.2011.11.011"},{"key":"ref94\/cit94","doi-asserted-by":"publisher","DOI":"10.1016\/j.jmr.2005.08.013"}],"container-title":["Biochemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acs.biochem.4c00692","content-type":"application\/pdf","content-version":"vor","intended-application":"unspecified"},{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acs.biochem.4c00692","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,3,4]],"date-time":"2025-03-04T09:11:25Z","timestamp":1741079485000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/acs.biochem.4c00692"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,2,17]]},"references-count":94,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2025,3,4]]}},"alternative-id":["10.1021\/acs.biochem.4c00692"],"URL":"https:\/\/doi.org\/10.1021\/acs.biochem.4c00692","relation":{},"ISSN":["0006-2960","1520-4995"],"issn-type":[{"value":"0006-2960","type":"print"},{"value":"1520-4995","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,2,17]]}}}