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Biol."},{"key":"ref15\/cit15","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1152\/physiol.00039.2009","volume":"25","author":"DeCoursey T. E.","year":"2010","journal-title":"Physiology"},{"key":"ref16\/cit16","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1002\/andp.18431340107","volume":"134","author":"Br\u00fccke E.","year":"1843","journal-title":"Annalen der Physik und Chemie"},{"key":"ref17\/cit17","doi-asserted-by":"crossref","first-page":"436","DOI":"10.1016\/0005-2736(78)90266-3","volume":"512","author":"Levitt D. G.","year":"1978","journal-title":"Biochim. Biophys. Acta"},{"key":"ref18\/cit18","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1113\/jphysiol.1955.sp005291","volume":"128","author":"Hodgkin A. L.","year":"1955","journal-title":"J. Physiol."},{"key":"ref19\/cit19","doi-asserted-by":"crossref","first-page":"1778","DOI":"10.1021\/bi701900x","volume":"47","author":"Slatin S. L.","year":"2008","journal-title":"Biochemistry"},{"key":"ref20\/cit20","volume-title":"Ion Channels of Excitable Membranes","author":"Hille B.","year":"2001","edition":"3"},{"key":"ref21\/cit21","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1016\/0005-2736(72)90179-4","volume":"274","author":"Myers V. B.","year":"1972","journal-title":"Biochim. Biophys. Acta"},{"key":"ref22\/cit22","doi-asserted-by":"crossref","first-page":"501","DOI":"10.1016\/S0006-3495(81)84805-9","volume":"35","author":"Dani J. A.","year":"1981","journal-title":"Biophys. J."},{"key":"ref23\/cit23","doi-asserted-by":"crossref","first-page":"20130799","DOI":"10.1098\/rsif.2013.0799","volume":"11","author":"DeCoursey T. E.","year":"2014","journal-title":"J. R. Soc., Interface"},{"key":"ref24\/cit24","doi-asserted-by":"crossref","first-page":"3190","DOI":"10.1021\/ja01359a511","volume":"53","author":"Huggins M. L.","year":"1931","journal-title":"J. Am. Chem. Soc."},{"key":"ref25\/cit25","doi-asserted-by":"crossref","first-page":"1419","DOI":"10.1021\/ja01452a015","volume":"42","author":"Latimer W. M.","year":"1920","journal-title":"J. Am. Chem. Soc."},{"key":"ref26\/cit26","first-page":"264","volume-title":"The Nature of the Chemical Bond and the Structure of Molecules and Crystals; An Introduction to Modern Structural Chemistry","author":"Pauling L.","year":"1939"},{"key":"ref27\/cit27","doi-asserted-by":"crossref","first-page":"415","DOI":"10.1085\/jgp.109.4.415","volume":"109","author":"DeCoursey T. E.","year":"1997","journal-title":"J. Gen. Physiol."},{"key":"ref28\/cit28","doi-asserted-by":"crossref","first-page":"503","DOI":"10.1085\/jgp.112.4.503","volume":"112","author":"DeCoursey T. E.","year":"1998","journal-title":"J. Gen. Physiol."},{"key":"ref29\/cit29","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1007\/BF00235130","volume":"141","author":"DeCoursey T. E.","year":"1994","journal-title":"J. Membr. 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A. (2014) inFunctional and structural studies of the human voltage-gated proton channel, pp209,MacKinnon Laboratory, Rockefeller University,New York."},{"key":"ref41\/cit41","doi-asserted-by":"crossref","first-page":"18162","DOI":"10.1073\/pnas.1115405108","volume":"108","author":"Smith S. M. E.","year":"2011","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"ref42\/cit42","doi-asserted-by":"crossref","first-page":"e1001085","DOI":"10.1371\/journal.pbio.1001085","volume":"9","author":"Taylor A. R.","year":"2011","journal-title":"PLoS Biol."},{"key":"ref43\/cit43","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1111\/nph.12225","volume":"199","author":"Bach L. T.","year":"2013","journal-title":"New Phytol."},{"key":"ref44\/cit44","doi-asserted-by":"crossref","first-page":"675","DOI":"10.1016\/j.tplants.2012.06.009","volume":"17","author":"Taylor A. R.","year":"2012","journal-title":"Trends Plant Sci."},{"key":"ref45\/cit45","doi-asserted-by":"publisher","DOI":"10.1089\/ars.2013.5806"},{"key":"ref46\/cit46","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1085\/jgp.200910379","volume":"136","author":"Iovannisci D.","year":"2010","journal-title":"J. Gen. Physiol."},{"key":"ref47\/cit47","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1038\/ni.1843","volume":"11","author":"Capasso M.","year":"2010","journal-title":"Nat. Immunol."},{"key":"ref48\/cit48","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1084\/jem.20091837","volume":"207","author":"El Chemaly A.","year":"2010","journal-title":"J. Exp. Med."},{"key":"ref49\/cit49","doi-asserted-by":"crossref","first-page":"18022","DOI":"10.1073\/pnas.0905565106","volume":"106","author":"Morgan D.","year":"2009","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"ref50\/cit50","doi-asserted-by":"crossref","first-page":"274","DOI":"10.1016\/j.bbrc.2009.03.036","volume":"382","author":"Okochi Y.","year":"2009","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"ref51\/cit51","doi-asserted-by":"crossref","first-page":"7642","DOI":"10.1073\/pnas.0902761106","volume":"106","author":"Ramsey I. S.","year":"2009","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"ref52\/cit52","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1042\/BJ20121188","volume":"450","author":"Sasaki M.","year":"2013","journal-title":"Biochem. J."},{"key":"ref53\/cit53","doi-asserted-by":"crossref","first-page":"18078","DOI":"10.1073\/pnas.1411390111","volume":"111","author":"Hondares E.","year":"2014","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"ref54\/cit54","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1113\/jphysiol.2002.028878","volume":"545","author":"Schilling T.","year":"2002","journal-title":"J. Physiol."},{"key":"ref55\/cit55","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1113\/jphysiol.1984.sp015241","volume":"351","author":"Byerly L.","year":"1984","journal-title":"J. Physiol."},{"key":"ref56\/cit56","first-page":"337","volume":"5","author":"Doroshenko P. A.","year":"1986","journal-title":"Gen. Physiol. Biophys."},{"key":"ref57\/cit57","doi-asserted-by":"crossref","first-page":"439","DOI":"10.1242\/jeb.145.1.439","volume":"145","author":"Mahaut-Smith M. P.","year":"1989","journal-title":"J. Exp. Biol."},{"key":"ref58\/cit58","doi-asserted-by":"crossref","first-page":"826","DOI":"10.1038\/299826a0","volume":"299","author":"Thomas R. C.","year":"1982","journal-title":"Nature"},{"key":"ref59\/cit59","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1113\/jphysiol.1984.sp015289","volume":"352","author":"Barish M. E.","year":"1984","journal-title":"J. Physiol."},{"key":"ref60\/cit60","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1007\/BF00233548","volume":"147","author":"Humez S.","year":"1995","journal-title":"J. Membr. Biol."},{"key":"ref61\/cit61","doi-asserted-by":"crossref","first-page":"1243","DOI":"10.1016\/S0006-3495(91)82158-0","volume":"60","author":"DeCoursey T. E.","year":"1991","journal-title":"Biophys. J."},{"key":"ref62\/cit62","doi-asserted-by":"crossref","first-page":"729","DOI":"10.1085\/jgp.102.4.729","volume":"102","author":"Kapus A.","year":"1993","journal-title":"J. Gen. Physiol."},{"key":"ref63\/cit63","doi-asserted-by":"crossref","first-page":"1590","DOI":"10.1016\/S0006-3495(93)81198-6","volume":"65","author":"DeCoursey T. E.","year":"1993","journal-title":"Biophys. J."},{"key":"ref64\/cit64","doi-asserted-by":"crossref","first-page":"526","DOI":"10.1007\/BF00373889","volume":"430","author":"Eder C.","year":"1995","journal-title":"Pfl\u00fcgers Arch."},{"key":"ref65\/cit65","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1113\/jphysiol.1993.sp019860","volume":"470","author":"Bernheim L.","year":"1993","journal-title":"J. Physiol."},{"key":"ref66\/cit66","doi-asserted-by":"crossref","first-page":"2203","DOI":"10.1074\/jbc.270.5.2203","volume":"270","author":"Nordstr\u00f6m T.","year":"1995","journal-title":"J. Biol. Chem."},{"key":"ref67\/cit67","first-page":"458","volume":"18","author":"Cherny V. V.","year":"2001","journal-title":"Biol. Membr."},{"key":"ref68\/cit68","doi-asserted-by":"crossref","first-page":"11020","DOI":"10.1073\/pnas.0800886105","volume":"105","author":"Musset B.","year":"2008","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"ref69\/cit69","doi-asserted-by":"crossref","first-page":"C736","DOI":"10.1152\/ajpcell.00369.2001","volume":"282","author":"Fischer H.","year":"2002","journal-title":"Am. J. Physiol."},{"key":"ref70\/cit70","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1113\/jphysiol.1996.sp021686","volume":"496","author":"Gordienko D. V.","year":"1996","journal-title":"J. Physiol."},{"key":"ref71\/cit71","doi-asserted-by":"crossref","first-page":"C1861","DOI":"10.1152\/ajpcell.1996.271.6.C1861","volume":"271","author":"Schrenzel J.","year":"1996","journal-title":"Am. J. Physiol."},{"key":"ref72\/cit72","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1186\/1471-2172-14-24","volume":"14","author":"Zhu X.","year":"2013","journal-title":"BMC Immunol."},{"key":"ref73\/cit73","doi-asserted-by":"crossref","first-page":"512","DOI":"10.1016\/j.bbrc.2005.12.038","volume":"340","author":"El Chemaly A.","year":"2006","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"ref74\/cit74","doi-asserted-by":"crossref","first-page":"C204","DOI":"10.1152\/ajpcell.00059.2012","volume":"303","author":"Szteyn K.","year":"2012","journal-title":"Am. J. Physiol."},{"key":"ref75\/cit75","doi-asserted-by":"crossref","first-page":"C286","DOI":"10.1152\/ajpcell.00335.2011","volume":"302","author":"Musset B.","year":"2012","journal-title":"Am. J. Physiol."},{"key":"ref76\/cit76","doi-asserted-by":"crossref","first-page":"21025","DOI":"10.1074\/jbc.M002386200","volume":"275","author":"Schapiro F. B.","year":"2000","journal-title":"J. Biol. Chem."},{"key":"ref77\/cit77","doi-asserted-by":"crossref","first-page":"996","DOI":"10.1016\/j.bbabio.2006.01.005","volume":"1757","author":"Murphy R.","year":"2006","journal-title":"Biochim. Biophys. Acta"},{"key":"ref78\/cit78","doi-asserted-by":"crossref","first-page":"e14081","DOI":"10.1371\/journal.pone.0014081","volume":"5","author":"Pethe\u0151 G. L.","year":"2010","journal-title":"PLoS One"},{"key":"ref79\/cit79","doi-asserted-by":"crossref","first-page":"1142","DOI":"10.1126\/science.147.3662.1142","volume":"147","author":"Eckert R.","year":"1965","journal-title":"Science"},{"key":"ref80\/cit80","doi-asserted-by":"crossref","first-page":"258","DOI":"10.1085\/jgp.52.2.258","volume":"52","author":"Eckert R.","year":"1968","journal-title":"J. Gen. Physiol."},{"key":"ref81\/cit81","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1002\/jcp.1030500105","volume":"50","author":"Hisada M.","year":"1957","journal-title":"J. Cell. Comp. Physiol."},{"key":"ref82\/cit82","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1007\/BF00610472","volume":"134","author":"Nawata T.","year":"1979","journal-title":"J. Comp. Physiol."},{"key":"ref83\/cit83","doi-asserted-by":"crossref","first-page":"723","DOI":"10.1083\/jcb.105.2.723","volume":"105","author":"Nicolas M. T.","year":"1987","journal-title":"J. Cell Biol."},{"issue":"14","key":"ref84\/cit84","first-page":"226","volume":"3","author":"de Quatrefages A.","year":"1850","journal-title":"Annales Des Sciences Naturelles Zoologie Series"},{"key":"ref85\/cit85","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1073\/pnas.3.1.15","volume":"3","author":"Harvey E. B.","year":"1917","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"ref86\/cit86","doi-asserted-by":"crossref","first-page":"1429","DOI":"10.1085\/jgp.50.5.1429","volume":"50","author":"Eckert R.","year":"1967","journal-title":"J. Gen. Physiol."},{"key":"ref87\/cit87","doi-asserted-by":"crossref","first-page":"690","DOI":"10.1073\/pnas.69.3.690","volume":"69","author":"Fogel M.","year":"1972","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"ref88\/cit88","doi-asserted-by":"crossref","first-page":"305","DOI":"10.1242\/jcs.11.1.305","volume":"11","author":"Fogel M.","year":"1972","journal-title":"J. Cell Sci."},{"key":"ref89\/cit89","doi-asserted-by":"crossref","first-page":"425a","DOI":"10.1016\/j.bpj.2014.11.2325","volume":"108","author":"Rodriguez J. D.","year":"2015","journal-title":"Biophys. J."},{"key":"ref90\/cit90","doi-asserted-by":"crossref","first-page":"12047","DOI":"10.1074\/jbc.M109.040360","volume":"285","author":"Li S. J.","year":"2010","journal-title":"J. Biol. Chem."},{"key":"ref91\/cit91","doi-asserted-by":"crossref","first-page":"352","DOI":"10.1038\/nsmb.2783","volume":"21","author":"Takeshita K.","year":"2014","journal-title":"Nat. Struct. Mol. Biol."},{"key":"ref92\/cit92","doi-asserted-by":"crossref","first-page":"816","DOI":"10.1038\/ncomms1823","volume":"3","author":"Fujiwara Y.","year":"2012","journal-title":"Nat. Commun."},{"key":"ref93\/cit93","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1085\/jgp.67.3.295","volume":"67","author":"Campbell D. T.","year":"1976","journal-title":"J. Gen. Physiol."},{"key":"ref94\/cit94","doi-asserted-by":"crossref","first-page":"788","DOI":"10.1113\/jphysiol.1965.sp007732","volume":"180","author":"Chandler W. K.","year":"1965","journal-title":"J. Physiol."},{"key":"ref95\/cit95","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1085\/jgp.68.3.327","volume":"68","author":"Ebert G. A.","year":"1976","journal-title":"J. Gen. Physiol."},{"key":"ref96\/cit96","doi-asserted-by":"crossref","first-page":"637","DOI":"10.1085\/jgp.59.6.637","volume":"59","author":"Hille B.","year":"1972","journal-title":"J. Gen. Physiol."},{"key":"ref97\/cit97","doi-asserted-by":"crossref","first-page":"494","DOI":"10.1016\/S0006-3495(92)81854-4","volume":"61","author":"Ravindran A.","year":"1992","journal-title":"Biophys. J."},{"key":"ref98\/cit98","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1085\/jgp.118.3.303","volume":"118","author":"LeMasurier M.","year":"2001","journal-title":"J. Gen. Physiol."},{"key":"ref99\/cit99","doi-asserted-by":"crossref","first-page":"599","DOI":"10.1152\/physrev.00011.2012","volume":"93","author":"DeCoursey T. E.","year":"2013","journal-title":"Physiol. Rev."},{"key":"ref100\/cit100","doi-asserted-by":"crossref","first-page":"861","DOI":"10.1085\/jgp.105.6.861","volume":"105","author":"Cherny V. V.","year":"1995","journal-title":"J. Gen. Physiol."},{"key":"ref101\/cit101","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1007\/s002329900092","volume":"152","author":"DeCoursey T. E.","year":"1996","journal-title":"J. Membr. Biol."},{"key":"ref102\/cit102","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1038\/nature10557","volume":"480","author":"Musset B.","year":"2011","journal-title":"Nature"},{"key":"ref103\/cit103","doi-asserted-by":"crossref","first-page":"469","DOI":"10.1085\/jgp.117.5.469","volume":"117","author":"Starace D. M.","year":"2001","journal-title":"J. Gen. Physiol."},{"key":"ref104\/cit104","doi-asserted-by":"crossref","first-page":"548","DOI":"10.1038\/nature02270","volume":"427","author":"Starace D. M.","year":"2004","journal-title":"Nature"},{"key":"ref105\/cit105","doi-asserted-by":"crossref","first-page":"1319","DOI":"10.1016\/S0896-6273(00)80422-5","volume":"19","author":"Starace D. M.","year":"1997","journal-title":"Neuron"},{"key":"ref106\/cit106","doi-asserted-by":"crossref","first-page":"1620","DOI":"10.1002\/pro.2158","volume":"21","author":"Hong M.","year":"2012","journal-title":"Protein Sci."},{"key":"ref107\/cit107","doi-asserted-by":"crossref","first-page":"11301","DOI":"10.1073\/pnas.94.21.11301","volume":"94","author":"Pinto L. H.","year":"1997","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"ref108\/cit108","doi-asserted-by":"crossref","first-page":"445","DOI":"10.1085\/jgp.201210856","volume":"141","author":"Kulleperuma K.","year":"2013","journal-title":"J. Gen. Physiol."},{"key":"ref109\/cit109","doi-asserted-by":"crossref","first-page":"180","DOI":"10.4161\/chan.28665","volume":"8","author":"Pupo A.","year":"2014","journal-title":"Channels"},{"key":"ref110\/cit110","doi-asserted-by":"crossref","first-page":"E273","DOI":"10.1073\/pnas.1318018111","volume":"111","author":"Chamberlin A.","year":"2014","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"ref111\/cit111","doi-asserted-by":"crossref","first-page":"625","DOI":"10.1085\/jgp.201311045","volume":"142","author":"Morgan D.","year":"2013","journal-title":"J. Gen. Physiol."},{"key":"ref112\/cit112","doi-asserted-by":"crossref","first-page":"286","DOI":"10.1016\/j.bbamem.2011.07.045","volume":"1818","author":"Wood M. L.","year":"2012","journal-title":"Biochim. Biophys. Acta"},{"key":"ref113\/cit113","doi-asserted-by":"crossref","first-page":"54153","DOI":"10.1074\/jbc.M410625200","volume":"279","author":"Carland J. E.","year":"2004","journal-title":"J. Biol. Chem."},{"key":"ref114\/cit114","doi-asserted-by":"crossref","first-page":"10977","DOI":"10.1074\/jbc.M009575200","volume":"276","author":"Gunthorpe M. J.","year":"2001","journal-title":"J. Biol. Chem."},{"key":"ref115\/cit115","doi-asserted-by":"crossref","first-page":"393","DOI":"10.1085\/jgp.20028552","volume":"119","author":"Keramidas A.","year":"2002","journal-title":"J. Gen. Physiol."},{"key":"ref116\/cit116","doi-asserted-by":"crossref","first-page":"4900","DOI":"10.1073\/pnas.87.13.4900","volume":"87","author":"Miller M. J.","year":"1990","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"ref117\/cit117","doi-asserted-by":"crossref","first-page":"3292","DOI":"10.1016\/S0021-9258(18)94065-2","volume":"264","author":"Cain B. D.","year":"1989","journal-title":"J. Biol. Chem."},{"key":"ref118\/cit118","first-page":"345","volume-title":"The Bacteria","author":"Fillingame R. H.","year":"1990"},{"key":"ref119\/cit119","doi-asserted-by":"crossref","first-page":"399","DOI":"10.1016\/0005-2728(87)90118-6","volume":"894","author":"Lightowlers R. N.","year":"1987","journal-title":"Biochim. Biophys. Acta"},{"key":"ref120\/cit120","doi-asserted-by":"crossref","first-page":"298","DOI":"10.1073\/pnas.75.1.298","volume":"75","author":"Nagle J. F.","year":"1978","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"ref121\/cit121","doi-asserted-by":"crossref","first-page":"1691","DOI":"10.1016\/S0006-3495(01)76140-1","volume":"80","author":"Brewer M. L.","year":"2001","journal-title":"Biophys. J."},{"key":"ref122\/cit122","doi-asserted-by":"crossref","first-page":"2489","DOI":"10.1016\/S0006-3495(97)78277-8","volume":"73","author":"Cukierman S.","year":"1997","journal-title":"Biophys. J."},{"key":"ref123\/cit123","doi-asserted-by":"crossref","first-page":"105902","DOI":"10.1103\/PhysRevLett.90.105902","volume":"90","author":"Dellago C.","year":"2003","journal-title":"Phys. Rev. Lett."},{"key":"ref124\/cit124","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1016\/S0006-3495(98)77492-2","volume":"75","author":"Pom\u00e8s R.","year":"1998","journal-title":"Biophys. J."},{"key":"ref125\/cit125","doi-asserted-by":"crossref","first-page":"2519","DOI":"10.1021\/jp9525752","volume":"100","author":"Pom\u00e8s R.","year":"1996","journal-title":"J. Phys. Chem."},{"key":"ref126\/cit126","doi-asserted-by":"crossref","first-page":"266","DOI":"10.1016\/j.abb.2004.09.018","volume":"433","author":"Guill\u00e9n Schlippe Y. V.","year":"2005","journal-title":"Arch. Biochem. Biophys."},{"key":"ref127\/cit127","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1126\/science.1117756","volume":"310","author":"Mohammed O. F.","year":"2005","journal-title":"Science"},{"key":"ref128\/cit128","doi-asserted-by":"crossref","first-page":"10320","DOI":"10.1038\/srep10320","volume":"5","author":"Dudev T.","year":"2015","journal-title":"Sci. Rep."},{"key":"ref129\/cit129","doi-asserted-by":"crossref","first-page":"35489","DOI":"10.1074\/jbc.M113.510909","volume":"288","author":"Luoto H. H.","year":"2013","journal-title":"J. Biol. Chem."},{"key":"ref130\/cit130","doi-asserted-by":"crossref","first-page":"399","DOI":"10.1038\/nature10963","volume":"484","author":"Lin S. M.","year":"2012","journal-title":"Nature"},{"key":"ref131\/cit131","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1038\/nature11524","volume":"490","author":"Sun L.","year":"2012","journal-title":"Nature"},{"key":"ref132\/cit132","first-page":"DOI: 10.1021\/jp","author":"Peng Y.","year":"2014","journal-title":"J. Phys. Chem. B"},{"key":"ref133\/cit133","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1085\/jgp.200910213","volume":"134","author":"Kuno M.","year":"2009","journal-title":"J. Gen. Physiol."},{"key":"ref134\/cit134","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1126\/science.280.5360.69","volume":"280","author":"Doyle D. A.","year":"1998","journal-title":"Science"},{"key":"ref135\/cit135","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1038\/415287a","volume":"415","author":"Dutzler R.","year":"2002","journal-title":"Nature"},{"key":"ref136\/cit136","doi-asserted-by":"crossref","first-page":"897","DOI":"10.1126\/science.1116269","volume":"309","author":"Long S. B.","year":"2005","journal-title":"Science"},{"key":"ref137\/cit137","doi-asserted-by":"crossref","first-page":"182","DOI":"10.1126\/science.2455344","volume":"241","author":"Wallace B. A.","year":"1988","journal-title":"Science"},{"key":"ref138\/cit138","doi-asserted-by":"crossref","first-page":"869","DOI":"10.1038\/nsmb.1826","volume":"17","author":"Ramsey I. S.","year":"2010","journal-title":"Nat. Struct. Mol. Biol."},{"key":"ref139\/cit139","doi-asserted-by":"crossref","first-page":"244","DOI":"10.1038\/nsmb.2768","volume":"21","author":"Li Q.","year":"2014","journal-title":"Nat. Struct. Mol. Biol."},{"key":"ref140\/cit140","doi-asserted-by":"crossref","first-page":"371","DOI":"10.1085\/jgp.200709745","volume":"129","author":"MacCallum J. L.","year":"2007","journal-title":"J. Gen. Physiol."},{"key":"ref141\/cit141","doi-asserted-by":"crossref","first-page":"424","DOI":"10.1113\/jphysiol.1952.sp004716","volume":"116","author":"Hodgkin A. L.","year":"1952","journal-title":"J. Physiol."},{"key":"ref142\/cit142","doi-asserted-by":"crossref","first-page":"1251","DOI":"10.1085\/jgp.97.6.1251","volume":"97","author":"Shapiro M. S.","year":"1991","journal-title":"J. Gen. Physiol."},{"key":"ref143\/cit143","doi-asserted-by":"crossref","first-page":"427","DOI":"10.1038\/291427a0","volume":"291","author":"Swenson R. P.","year":"1981","journal-title":"Nature"},{"key":"ref144\/cit144","first-page":"285","volume":"3","author":"Katz B.","year":"1949","journal-title":"Arch. Sci. Physiol."},{"key":"ref145\/cit145","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1113\/jphysiol.1979.sp012849","volume":"292","author":"Hagiwara S.","year":"1979","journal-title":"J. Physiol."},{"key":"ref146\/cit146","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1085\/jgp.108.4.237","volume":"108","author":"Chen T. Y.","year":"1996","journal-title":"J. Gen. Physiol."},{"key":"ref147\/cit147","doi-asserted-by":"crossref","first-page":"527","DOI":"10.1038\/373527a0","volume":"373","author":"Pusch M.","year":"1995","journal-title":"Nature"},{"key":"ref148\/cit148","doi-asserted-by":"crossref","first-page":"1564","DOI":"10.1016\/j.bpj.2014.08.017","volume":"107","author":"Villalba-Galea C. A.","year":"2014","journal-title":"Biophys. J."},{"key":"ref149\/cit149","first-page":"265","volume":"17","author":"Nawata T.","year":"1976","journal-title":"Plant Cell Physiol."},{"key":"ref150\/cit150","doi-asserted-by":"crossref","first-page":"586","DOI":"10.1126\/science.161.3841.586","volume":"161","author":"Krieger N.","year":"1968","journal-title":"Science"},{"key":"ref151\/cit151","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1002\/jcp.1040870115","volume":"87","author":"Schmitter R. E.","year":"1976","journal-title":"J. Cell. Physiol."},{"key":"ref152\/cit152","doi-asserted-by":"crossref","first-page":"310","DOI":"10.1016\/0003-9861(71)90289-X","volume":"142","author":"Fogel M.","year":"1971","journal-title":"Arch. Biochem. Biophys."},{"key":"ref153\/cit153","doi-asserted-by":"crossref","first-page":"1115","DOI":"10.1016\/B978-012656976-6\/50157-8","volume-title":"Cell Physiology Sourcebook: A Molecular Approach","author":"Hastings J. W.","year":"2001"},{"key":"ref154\/cit154","doi-asserted-by":"crossref","first-page":"6885","DOI":"10.1073\/pnas.100047297","volume":"97","author":"DeCoursey T. E.","year":"2000","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"ref155\/cit155","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1084\/jem.190.2.183","volume":"190","author":"B\u00e1nfi B.","year":"1999","journal-title":"J. Exp. Med."},{"key":"ref156\/cit156","doi-asserted-by":"crossref","first-page":"767","DOI":"10.1111\/j.1469-7793.2001.00767.x","volume":"535","author":"DeCoursey T. E.","year":"2001","journal-title":"J. Physiol."},{"key":"ref157\/cit157","doi-asserted-by":"crossref","first-page":"2069","DOI":"10.1359\/jbmr.2003.18.11.2069","volume":"18","author":"Mori H.","year":"2003","journal-title":"J. Bone Miner. Res."},{"key":"ref158\/cit158","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1113\/jphysiol.2006.124248","volume":"579","author":"Morgan D.","year":"2007","journal-title":"J. Physiol."},{"key":"ref159\/cit159","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1152\/ajplegacy.1932.103.1.235","volume":"103","author":"Baldridge C. W.","year":"1932","journal-title":"Am. J. Physiol."},{"key":"ref160\/cit160","doi-asserted-by":"crossref","first-page":"1355","DOI":"10.1016\/S0021-9258(18)70011-2","volume":"234","author":"Sbarra A. J.","year":"1959","journal-title":"J. Biol. Chem."},{"key":"ref161\/cit161","doi-asserted-by":"crossref","first-page":"1464","DOI":"10.1182\/blood.V93.5.1464","volume":"93","author":"Babior B. M.","year":"1999","journal-title":"Blood"},{"key":"ref162\/cit162","doi-asserted-by":"crossref","first-page":"401","DOI":"10.1042\/BJ20041835","volume":"386","author":"Groemping Y.","year":"2005","journal-title":"Biochem. J."},{"key":"ref163\/cit163","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1007\/s00418-004-0679-8","volume":"122","author":"Nauseef W. M.","year":"2004","journal-title":"Histochem. Cell Biol."},{"key":"ref164\/cit164","doi-asserted-by":"crossref","first-page":"677","DOI":"10.1002\/jlb.60.6.677","volume":"60","author":"DeLeo F. R.","year":"1996","journal-title":"J. Leukocyte Biol."},{"key":"ref165\/cit165","doi-asserted-by":"crossref","first-page":"4574","DOI":"10.4049\/jimmunol.163.8.4574","volume":"163","author":"Nixon J. B.","year":"1999","journal-title":"J. Immunol."},{"key":"ref166\/cit166","doi-asserted-by":"crossref","first-page":"2173","DOI":"10.1007\/s00018-005-5177-1","volume":"62","author":"DeCoursey T. E.","year":"2005","journal-title":"Cell. Mol. Life Sci."},{"key":"ref167\/cit167","doi-asserted-by":"crossref","first-page":"5911","DOI":"10.1016\/S0021-9258(19)67684-2","volume":"266","author":"Nauseef W. M.","year":"1991","journal-title":"J. Biol. Chem."},{"key":"ref168\/cit168","doi-asserted-by":"crossref","first-page":"325","DOI":"10.1042\/bj2460325","volume":"246","author":"Henderson L. M.","year":"1987","journal-title":"Biochem. J."},{"key":"ref169\/cit169","doi-asserted-by":"crossref","first-page":"563","DOI":"10.1042\/bj2510563","volume":"251","author":"Henderson L. M.","year":"1988","journal-title":"Biochem. J."},{"key":"ref170\/cit170","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1113\/jphysiol.1993.sp019723","volume":"466","author":"Demaurex N.","year":"1993","journal-title":"J. Physiol."},{"key":"ref171\/cit171","doi-asserted-by":"crossref","first-page":"531","DOI":"10.1038\/nature01523","volume":"422","author":"DeCoursey T. E.","year":"2003","journal-title":"Nature"},{"key":"ref172\/cit172","first-page":"285","volume":"255","author":"Henderson L. M.","year":"1988","journal-title":"Biochem. J."},{"key":"ref173\/cit173","doi-asserted-by":"crossref","first-page":"3221","DOI":"10.1242\/jcs.00627","volume":"116","author":"Bankers-Fulbright J. L.","year":"2003","journal-title":"J. Cell Sci."},{"key":"ref174\/cit174","doi-asserted-by":"crossref","first-page":"2315","DOI":"10.1098\/rstb.2005.1769","volume":"360","author":"Demaurex N.","year":"2005","journal-title":"Philos. Trans. R. Soc., B"},{"key":"ref175\/cit175","doi-asserted-by":"crossref","first-page":"2947","DOI":"10.1182\/blood-2004-03-1005","volume":"104","author":"Rada B. K.","year":"2004","journal-title":"Blood"},{"key":"ref176\/cit176","doi-asserted-by":"crossref","first-page":"565","DOI":"10.1038\/nn.3059","volume":"15","author":"Wu L. J.","year":"2012","journal-title":"Nat. Neurosci."},{"key":"ref177\/cit177","doi-asserted-by":"crossref","first-page":"541","DOI":"10.1161\/HYPERTENSIONAHA.114.03549","volume":"64","author":"Jin C.","year":"2014","journal-title":"Hypertension"},{"key":"ref178\/cit178","doi-asserted-by":"crossref","first-page":"306","DOI":"10.1002\/jcp.10022","volume":"189","author":"Bankers-Fulbright J. L.","year":"2001","journal-title":"J. Cell. Physiol."},{"key":"ref179\/cit179","doi-asserted-by":"crossref","first-page":"783","DOI":"10.1111\/j.1469-7793.2001.00783.x","volume":"535","author":"Cherny V. V.","year":"2001","journal-title":"J. Physiol."},{"key":"ref180\/cit180","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1042\/bj2830171","volume":"283","author":"Henderson L. M.","year":"1992","journal-title":"Biochem. J."},{"key":"ref181\/cit181","doi-asserted-by":"crossref","first-page":"5117","DOI":"10.1074\/jbc.C109.082727","volume":"285","author":"Musset B.","year":"2010","journal-title":"J. Biol. Chem."},{"key":"ref182\/cit182","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1016\/0008-8749(84)90066-2","volume":"88","author":"Bromberg Y.","year":"1984","journal-title":"Cell. Immunol."},{"key":"ref183\/cit183","doi-asserted-by":"crossref","first-page":"4736","DOI":"10.1016\/S0021-9258(17)37606-8","volume":"269","author":"Kapus A.","year":"1994","journal-title":"J. Biol. Chem."},{"key":"ref184\/cit184","doi-asserted-by":"crossref","first-page":"2477","DOI":"10.1113\/jphysiol.2007.149427","volume":"586","author":"Musset B.","year":"2008","journal-title":"J. Physiol."},{"key":"ref185\/cit185","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1016\/j.febslet.2008.12.005","volume":"583","author":"Musset B.","year":"2009","journal-title":"FEBS Lett."},{"key":"ref186\/cit186","doi-asserted-by":"crossref","first-page":"3447","DOI":"10.4049\/jimmunol.136.9.3447","volume":"136","author":"de Boer M.","year":"1986","journal-title":"J. Immunol."},{"key":"ref187\/cit187","doi-asserted-by":"crossref","first-page":"36063","DOI":"10.1074\/jbc.C100352200","volume":"276","author":"DeCoursey T. E.","year":"2001","journal-title":"J. Biol. Chem."},{"key":"ref188\/cit188","doi-asserted-by":"crossref","first-page":"475","DOI":"10.1152\/physrev.00028.2002","volume":"83","author":"DeCoursey T. E.","year":"2003","journal-title":"Physiol. Rev."},{"key":"ref189\/cit189","doi-asserted-by":"crossref","first-page":"734","DOI":"10.1038\/33725","volume":"392","author":"Schrenzel J.","year":"1998","journal-title":"Nature"},{"key":"ref190\/cit190","doi-asserted-by":"crossref","first-page":"419","DOI":"10.1113\/jphysiol.2005.094748","volume":"569","author":"Morgan D.","year":"2005","journal-title":"J. Physiol."},{"key":"ref191\/cit191","doi-asserted-by":"crossref","first-page":"371","DOI":"10.1113\/jphysiol.2001.013055","volume":"538","author":"Schwiening C. J.","year":"2002","journal-title":"J. Physiol."},{"key":"ref192\/cit192","doi-asserted-by":"crossref","first-page":"e10","DOI":"10.2500\/ajra.2009.23.3389","volume":"23","author":"Cho D. Y.","year":"2009","journal-title":"American Journal of Rhinology & Allergy"},{"key":"ref193\/cit193","first-page":"247","volume":"1","author":"Fischer H.","year":"2012","journal-title":"Wiley Interdiscip. Rev.: Membr. Transp. Signaling"},{"key":"ref194\/cit194","doi-asserted-by":"crossref","first-page":"9376","DOI":"10.1074\/jbc.M111.314955","volume":"287","author":"Musset B.","year":"2012","journal-title":"J. Biol. Chem."},{"key":"ref195\/cit195","doi-asserted-by":"crossref","first-page":"15041","DOI":"10.1016\/S0021-9258(18)48135-5","volume":"262","author":"Babcock D. F.","year":"1987","journal-title":"J. Biol. Chem."},{"key":"ref196\/cit196","doi-asserted-by":"crossref","first-page":"1327","DOI":"10.1073\/pnas.80.5.1327","volume":"80","author":"Babcock D. F.","year":"1983","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"ref197\/cit197","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1016\/j.cell.2009.12.053","volume":"140","author":"Lishko P. V.","year":"2010","journal-title":"Cell"},{"key":"ref198\/cit198","doi-asserted-by":"crossref","first-page":"696","DOI":"10.1042\/bj0550696","volume":"55","author":"Mawson C. A.","year":"1953","journal-title":"Biochem. J."},{"key":"ref199\/cit199","doi-asserted-by":"crossref","first-page":"475","DOI":"10.1093\/oxfordjournals.humrep.a136573","volume":"2","author":"Saaranen M.","year":"1987","journal-title":"Hum. Reprod."},{"key":"ref200\/cit200","doi-asserted-by":"crossref","first-page":"819","DOI":"10.1085\/jgp.114.6.819","volume":"114","author":"Cherny V. V.","year":"1999","journal-title":"J. Gen. Physiol."},{"key":"ref201\/cit201","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1016\/S0301-0082(00)00062-9","volume":"64","author":"Eder C.","year":"2001","journal-title":"Prog. Neurobiol."},{"key":"ref202\/cit202","doi-asserted-by":"crossref","first-page":"1804","DOI":"10.1016\/j.jprot.2010.03.010","volume":"73","author":"Boyd R. S.","year":"2010","journal-title":"J. Proteomics"},{"key":"ref203\/cit203","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1016\/j.tcb.2010.09.006","volume":"21","author":"Capasso M.","year":"2011","journal-title":"Trends Cell Biol."},{"key":"ref204\/cit204","doi-asserted-by":"crossref","first-page":"470","DOI":"10.1165\/rcmb.2011-0204OC","volume":"46","author":"Howden R.","year":"2012","journal-title":"Am. J. Respir. Cell Mol. Biol."},{"key":"ref205\/cit205","doi-asserted-by":"crossref","first-page":"e56989","DOI":"10.1371\/journal.pone.0056989","volume":"8","author":"Haglund S.","year":"2013","journal-title":"PLoS One"},{"key":"ref206\/cit206","doi-asserted-by":"crossref","first-page":"e104080","DOI":"10.1371\/journal.pone.0104080","volume":"9","author":"Conese M.","year":"2014","journal-title":"PLoS One"},{"key":"ref207\/cit207","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1016\/j.bbrc.2011.07.102","volume":"412","author":"Wang Y.","year":"2011","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"ref208\/cit208","doi-asserted-by":"crossref","first-page":"13877","DOI":"10.1074\/jbc.M112.345280","volume":"287","author":"Wang Y.","year":"2012","journal-title":"J. Biol. Chem."},{"key":"ref209\/cit209","doi-asserted-by":"crossref","first-page":"e70550","DOI":"10.1371\/journal.pone.0070550","volume":"8","author":"Wang Y.","year":"2013","journal-title":"PLoS One"},{"key":"ref210\/cit210","doi-asserted-by":"crossref","first-page":"587a","DOI":"10.1016\/j.bpj.2014.11.3200","volume":"108","author":"Morgan D.","year":"2015","journal-title":"Biophys. J."},{"key":"ref211\/cit211","first-page":"309","volume":"152","author":"Warburg O.","year":"1924","journal-title":"Biochem. Z."},{"key":"ref212\/cit212","doi-asserted-by":"crossref","first-page":"312","DOI":"10.1016\/j.bbrc.2013.07.067","volume":"438","author":"Wang Y.","year":"2013","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"ref213\/cit213","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1016\/B978-0-12-386931-9.00012-X","volume":"117","author":"Smith S. M. E.","year":"2013","journal-title":"Prog. Mol. Biol. Transl. Sci."},{"key":"ref214\/cit214","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1038\/nsmb.1739","volume":"17","author":"Gonzalez C.","year":"2010","journal-title":"Nat. Struct. Mol. Biol."},{"key":"ref215\/cit215","doi-asserted-by":"crossref","first-page":"274","DOI":"10.1016\/j.neuron.2012.11.013","volume":"77","author":"Hong L.","year":"2013","journal-title":"Neuron"},{"key":"ref216\/cit216","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1085\/jgp.201210857","volume":"141","author":"Gonzalez C.","year":"2013","journal-title":"J. Gen. Physiol."},{"key":"ref217\/cit217","doi-asserted-by":"crossref","first-page":"1190","DOI":"10.3109\/10715762.2014.938234","volume":"48","author":"Kov\u00e1cs I.","year":"2014","journal-title":"Free Radical Res."},{"key":"ref218\/cit218","first-page":"2400","volume":"13","author":"DeCoursey T. E.","year":"2007","journal-title":"Curr. Pharm. Des."},{"key":"ref219\/cit219","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1113\/jphysiol.1989.sp017642","volume":"413","author":"Byerly L.","year":"1989","journal-title":"J. Physiol."},{"key":"ref220\/cit220","doi-asserted-by":"crossref","first-page":"455","DOI":"10.1242\/jeb.145.1.455","volume":"145","author":"Mahaut-Smith M. P.","year":"1989","journal-title":"J. Exp. Biol."},{"key":"ref221\/cit221","doi-asserted-by":"crossref","first-page":"433","DOI":"10.1113\/jphysiol.1987.sp016710","volume":"390","author":"Meech R. W.","year":"1987","journal-title":"J. Physiol."},{"key":"ref222\/cit222","first-page":"F289","volume":"269","author":"Gu X.","year":"1995","journal-title":"Am. J. Physiol."},{"key":"ref223\/cit223","doi-asserted-by":"crossref","first-page":"575a","DOI":"10.1016\/j.bpj.2011.11.3133","volume":"102","author":"Morgan D.","year":"2012","journal-title":"Biophys. J."},{"key":"ref224\/cit224","doi-asserted-by":"crossref","first-page":"370","DOI":"10.1038\/nature06266","volume":"450","author":"Alabi A. A.","year":"2007","journal-title":"Nature"},{"key":"ref225\/cit225","doi-asserted-by":"crossref","first-page":"256","DOI":"10.1016\/j.ejphar.2014.05.049","volume":"738","author":"Shin H.","year":"2014","journal-title":"Eur. J. Pharmacol."},{"key":"ref226\/cit226","doi-asserted-by":"crossref","first-page":"755","DOI":"10.1085\/jgp.103.5.755","volume":"103","author":"DeCoursey T. E.","year":"1994","journal-title":"J. Gen. Physiol."},{"key":"ref227\/cit227","doi-asserted-by":"crossref","first-page":"827","DOI":"10.1113\/jphysiol.2011.218149","volume":"590","author":"Matsuura T.","year":"2012","journal-title":"J. Physiol."},{"key":"ref228\/cit228","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1016\/j.brainres.2011.11.041","volume":"1435","author":"Song J. H.","year":"2012","journal-title":"Brain Res."},{"key":"ref229\/cit229","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1016\/j.ejphar.2015.03.003","volume":"755","author":"Shin H.","year":"2015","journal-title":"Eur. J. Pharmacol."},{"key":"ref230\/cit230","doi-asserted-by":"crossref","first-page":"94","DOI":"10.1016\/j.neulet.2012.03.065","volume":"516","author":"Song J. H.","year":"2012","journal-title":"Neurosci. Lett."},{"key":"ref231\/cit231","doi-asserted-by":"crossref","first-page":"154","DOI":"10.1016\/j.ejphar.2012.11.036","volume":"698","author":"Jin S.","year":"2013","journal-title":"Eur. J. Pharmacol."},{"key":"ref232\/cit232","doi-asserted-by":"crossref","first-page":"745","DOI":"10.1085\/jgp.106.4.745","volume":"106","author":"DeCoursey T. E.","year":"1995","journal-title":"J. Gen. Physiol."},{"key":"ref233\/cit233","doi-asserted-by":"crossref","first-page":"475","DOI":"10.1085\/jgp.69.4.475","volume":"69","author":"Hille B.","year":"1977","journal-title":"J. Gen. Physiol."},{"key":"ref234\/cit234","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1016\/S0022-3565(25)28442-7","volume":"171","author":"Narahashi T.","year":"1970","journal-title":"J. Pharmacol. Exp. Ther."},{"key":"ref235\/cit235","doi-asserted-by":"crossref","first-page":"459","DOI":"10.1016\/S0022-3565(25)22916-0","volume":"255","author":"Jacobs E. R.","year":"1990","journal-title":"J. Pharmacol. Exp. Ther."},{"key":"ref236\/cit236","doi-asserted-by":"crossref","first-page":"9971","DOI":"10.1073\/pnas.1324012111","volume":"111","author":"Hong L.","year":"2014","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"ref237\/cit237","doi-asserted-by":"crossref","first-page":"5305","DOI":"10.1113\/jphysiol.2008.161703","volume":"586","author":"DeCoursey T. E.","year":"2008","journal-title":"J. Physiol."}],"container-title":["Biochemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acs.biochem.5b00353","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,5,27]],"date-time":"2025-05-27T23:22:00Z","timestamp":1748388120000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/acs.biochem.5b00353"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,5,20]]},"references-count":237,"journal-issue":{"issue":"21","published-print":{"date-parts":[[2015,6,2]]}},"alternative-id":["10.1021\/acs.biochem.5b00353"],"URL":"https:\/\/doi.org\/10.1021\/acs.biochem.5b00353","relation":{},"ISSN":["0006-2960","1520-4995"],"issn-type":[{"value":"0006-2960","type":"print"},{"value":"1520-4995","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,5,20]]}}}