{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,27]],"date-time":"2026-10-27T00:46:58Z","timestamp":1793062018904,"version":"4.5.0"},"reference-count":53,"publisher":"American Chemical Society (ACS)","issue":"16","license":[{"start":{"date-parts":[[2025,8,6]],"date-time":"2025-08-06T00:00:00Z","timestamp":1754438400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2025,8,6]],"date-time":"2025-08-06T00:00:00Z","timestamp":1754438400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2025,8,6]],"date-time":"2025-08-06T00:00:00Z","timestamp":1754438400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-045"}],"funder":[{"DOI":"10.13039\/100009455","name":"West Virginia University","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100009455","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Biochemistry"],"published-print":{"date-parts":[[2025,8,19]]},"DOI":"10.1021\/acs.biochem.5c00290","type":"journal-article","created":{"date-parts":[[2025,8,6]],"date-time":"2025-08-06T09:30:46Z","timestamp":1754472646000},"page":"3610-3622","source":"Crossref","is-referenced-by-count":2,"title":["Amyloidogenic SARS-CoV-2 Spike Protein-Derived Peptides Form Oligomers and Selectively Damage Lipid Membranes"],"prefix":"10.1021","volume":"64","author":[{"given":"Anjola","family":"Adewoye","sequence":"first","affiliation":[{"name":"The C. Eugene Bennett Department of Chemistry, West Virginia University, 217 Clark Hall, Morgantown, West Virginia 26506, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ephraim","family":"Ezeigbo","sequence":"additional","affiliation":[{"name":"The C. Eugene Bennett Department of Chemistry, West Virginia University, 217 Clark Hall, Morgantown, West Virginia 26506, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Quan H.","family":"Vo","sequence":"additional","affiliation":[{"name":"Department of Biochemistry and Molecular Biology, University of Nevada, 1664 N. Virginia Street, Reno, Nevada 89557, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5262-1867","authenticated-orcid":true,"given":"Justin","family":"Legleiter","sequence":"additional","affiliation":[{"name":"Department of Biochemistry and Molecular Biology, University of Nevada, 1664 N. Virginia Street, Reno, Nevada 89557, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2025,8,6]]},"reference":[{"key":"ref1\/cit1","doi-asserted-by":"publisher","DOI":"10.1016\/j.arcmed.2020.05.012"},{"key":"ref2\/cit2","doi-asserted-by":"publisher","DOI":"10.1038\/s41580-021-00418-x"},{"key":"ref3\/cit3","doi-asserted-by":"publisher","DOI":"10.1038\/s41564-021-00908-w"},{"key":"ref4\/cit4","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.2c03925"},{"key":"ref5\/cit5","doi-asserted-by":"publisher","DOI":"10.1039\/D4NR03030C"},{"key":"ref6\/cit6","doi-asserted-by":"publisher","DOI":"10.1021\/acsnano.1c10658"},{"key":"ref7\/cit7","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-022-30932-1"},{"key":"ref8\/cit8","doi-asserted-by":"publisher","DOI":"10.1101\/2023.09.01.555834"},{"key":"ref9\/cit9","doi-asserted-by":"publisher","DOI":"10.1039\/C9SC06501F"},{"key":"ref10\/cit10","doi-asserted-by":"publisher","DOI":"10.1101\/2023.09.01.555834"},{"key":"ref11\/cit11","doi-asserted-by":"publisher","DOI":"10.1007\/s00109-013-1025-1"},{"key":"ref12\/cit12","doi-asserted-by":"publisher","DOI":"10.3934\/biophy.2019.1.1"},{"key":"ref13\/cit13","doi-asserted-by":"publisher","DOI":"10.1021\/acs.chemrev.0c01122"},{"key":"ref14\/cit14","doi-asserted-by":"publisher","DOI":"10.1016\/j.bpc.2024.107202"},{"key":"ref15\/cit15","doi-asserted-by":"publisher","DOI":"10.3389\/fneur.2013.00017"},{"key":"ref16\/cit16","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1219059110"},{"key":"ref17\/cit17","doi-asserted-by":"publisher","DOI":"10.1002\/anie.202215785"},{"key":"ref18\/cit18","doi-asserted-by":"publisher","DOI":"10.1021\/bi500792f"},{"key":"ref19\/cit19","doi-asserted-by":"publisher","DOI":"10.1016\/j.bpc.2023.107091"},{"key":"ref20\/cit20","doi-asserted-by":"publisher","DOI":"10.1016\/j.bpj.2012.06.045"},{"key":"ref21\/cit21","doi-asserted-by":"publisher","DOI":"10.3233\/JPD-171103"},{"key":"ref22\/cit22","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbamem.2021.183663"},{"key":"ref23\/cit23","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jpcb.1c10254"},{"key":"ref24\/cit24","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbamem.2020.183497"},{"key":"ref25\/cit25","doi-asserted-by":"publisher","DOI":"10.1021\/acs.biochem.6b01016"},{"key":"ref26\/cit26","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1305517110"},{"key":"ref27\/cit27","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbamem.2007.09.018"},{"key":"ref28\/cit28","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jpclett.3c02613"},{"key":"ref29\/cit29","author":"Sedighi F.","year":"2023","journal-title":"bioRxiv"},{"key":"ref30\/cit30","doi-asserted-by":"publisher","DOI":"10.1038\/srep32721"},{"key":"ref31\/cit31","doi-asserted-by":"publisher","DOI":"10.1021\/acsnano.3c10889"},{"key":"ref32\/cit32","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M210207200"},{"key":"ref33\/cit33","doi-asserted-by":"publisher","DOI":"10.1016\/j.ymeth.2010.12.028"},{"key":"ref34\/cit34","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcis.2004.05.009"},{"key":"ref35\/cit35","doi-asserted-by":"publisher","DOI":"10.1016\/j.bpj.2009.08.034"},{"key":"ref36\/cit36","doi-asserted-by":"publisher","DOI":"10.1021\/cn2000475"},{"key":"ref37\/cit37","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbamem.2013.04.025"},{"key":"ref38\/cit38","doi-asserted-by":"publisher","DOI":"10.1021\/acsomega.7b01472"},{"key":"ref39\/cit39","doi-asserted-by":"publisher","DOI":"10.3390\/ph17060788"},{"key":"ref40\/cit40","doi-asserted-by":"publisher","DOI":"10.1080\/19336896.2023.2194212"},{"key":"ref41\/cit41","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2023.1117464"},{"key":"ref42\/cit42","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbi.2023.01.010"},{"key":"ref43\/cit43","doi-asserted-by":"publisher","DOI":"10.3390\/biomedicines11041215"},{"key":"ref44\/cit44","doi-asserted-by":"publisher","DOI":"10.1021\/acschemneuro.4c00636"},{"key":"ref45\/cit45","doi-asserted-by":"publisher","DOI":"10.1021\/acsami.3c09815"},{"key":"ref46\/cit46","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijbiomac.2024.137930"},{"key":"ref47\/cit47","doi-asserted-by":"publisher","DOI":"10.7717\/peerj.5"},{"key":"ref48\/cit48","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbamem.2018.02.022"},{"key":"ref49\/cit49","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbamem.2018.03.015"},{"key":"ref50\/cit50","doi-asserted-by":"publisher","DOI":"10.1038\/ncb1830"},{"key":"ref51\/cit51","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-018-03509-0"},{"key":"ref52\/cit52","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M116.761189"},{"key":"ref53\/cit53","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-019-40483-z"}],"container-title":["Biochemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acs.biochem.5c00290","content-type":"application\/pdf","content-version":"vor","intended-application":"unspecified"},{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acs.biochem.5c00290","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,19]],"date-time":"2025-08-19T08:10:42Z","timestamp":1755591042000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/acs.biochem.5c00290"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,8,6]]},"references-count":53,"journal-issue":{"issue":"16","published-print":{"date-parts":[[2025,8,19]]}},"alternative-id":["10.1021\/acs.biochem.5c00290"],"URL":"https:\/\/doi.org\/10.1021\/acs.biochem.5c00290","relation":{},"ISSN":["0006-2960","1520-4995"],"issn-type":[{"value":"0006-2960","type":"print"},{"value":"1520-4995","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,8,6]]}}}