{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,10]],"date-time":"2026-01-10T01:36:43Z","timestamp":1768009003861,"version":"3.49.0"},"reference-count":34,"publisher":"American Chemical Society (ACS)","issue":"21","funder":[{"DOI":"10.13039\/501100002749","name":"Federaal Wetenschapsbeleid","doi-asserted-by":"publisher","award":["IUAP 7\/10"],"award-info":[{"award-number":["IUAP 7\/10"]}],"id":[{"id":"10.13039\/501100002749","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003130","name":"Fonds Wetenschappelijk Onderzoek","doi-asserted-by":"publisher","award":["G.0433.12"],"award-info":[{"award-number":["G.0433.12"]}],"id":[{"id":"10.13039\/501100003130","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003130","name":"Fonds Wetenschappelijk Onderzoek","doi-asserted-by":"publisher","award":["G0E3414N"],"award-info":[{"award-number":["G0E3414N"]}],"id":[{"id":"10.13039\/501100003130","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Biochemistry"],"published-print":{"date-parts":[[2016,5,31]]},"DOI":"10.1021\/acs.biochem.6b00139","type":"journal-article","created":{"date-parts":[[2016,5,9]],"date-time":"2016-05-09T19:00:18Z","timestamp":1462820418000},"page":"2927-2935","source":"Crossref","is-referenced-by-count":6,"title":["Active Sites of Spinoxin, a Potassium Channel Scorpion Toxin, Elucidated by Systematic Alanine Scanning"],"prefix":"10.1021","volume":"55","author":[{"given":"Steve","family":"Peigneur","sequence":"first","affiliation":[{"name":"Toxicology and Pharmacology, University of Leuven, Campus Gasthuisberg O&N2, Herestraat 49, P.O. Box 922, Leuven 3000, Belgium"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yoko","family":"Yamaguchi","sequence":"additional","affiliation":[{"name":"Department of Environment Sciences, Fukuoka Women\u2019s University, Fukuoka 813-8529, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chihiro","family":"Kawano","sequence":"additional","affiliation":[{"name":"Department of Environment Sciences, Fukuoka Women\u2019s University, Fukuoka 813-8529, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takeru","family":"Nose","sequence":"additional","affiliation":[{"name":"Faculty of Arts and Science, Kyushu University, Fukuoka, 819-0395, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Selvanayagam","family":"Nirthanan","sequence":"additional","affiliation":[{"name":"Menzies Health Institute Queensland, Gold Coast, Queensland 4222, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ponnampalam","family":"Gopalakrishnakone","sequence":"additional","affiliation":[{"name":"Venom and Toxin Research Program, Yong Loo Lin School\rof Medicine, National University of Singapore, Singapore 117597, Singapore"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jan","family":"Tytgat","sequence":"additional","affiliation":[{"name":"Toxicology and Pharmacology, University of Leuven, Campus Gasthuisberg O&N2, Herestraat 49, P.O. Box 922, Leuven 3000, Belgium"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kazuki","family":"Sato","sequence":"additional","affiliation":[{"name":"Department of Environment Sciences, Fukuoka Women\u2019s University, Fukuoka 813-8529, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"316","published-online":{"date-parts":[[2016,5,18]]},"reference":[{"key":"ref1\/cit1","doi-asserted-by":"publisher","DOI":"10.17219\/acem\/22339"},{"key":"ref2\/cit2","doi-asserted-by":"publisher","DOI":"10.1517\/14728220903018957"},{"key":"ref3\/cit3","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0605136103"},{"key":"ref4\/cit4","doi-asserted-by":"publisher","DOI":"10.2174\/156800909790192400"},{"key":"ref5\/cit5","doi-asserted-by":"publisher","DOI":"10.1016\/S0165-6147(99)01398-X"},{"key":"ref6\/cit6","doi-asserted-by":"publisher","DOI":"10.1016\/j.toxicon.2004.03.022"},{"key":"ref7\/cit7","first-page":"283","volume-title":"Peptide Science 2003","author":"Sugahara Y.","year":"2004"},{"key":"ref8\/cit8","first-page":"185","volume-title":"Peptide Science 2012","author":"Yamaguchi Y.","year":"2013"},{"key":"ref9\/cit9","doi-asserted-by":"publisher","DOI":"10.1046\/j.1432-1033.2003.03743.x"},{"key":"ref10\/cit10","doi-asserted-by":"publisher","DOI":"10.1111\/j.1432-1033.1996.0491r.x"},{"key":"ref11\/cit11","doi-asserted-by":"publisher","DOI":"10.1016\/S0014-5793(97)00285-8"},{"key":"ref12\/cit12","doi-asserted-by":"publisher","DOI":"10.1111\/j.1742-4658.2008.06607.x"},{"key":"ref13\/cit13","doi-asserted-by":"publisher","DOI":"10.1042\/bj20030115"},{"key":"ref14\/cit14","doi-asserted-by":"publisher","DOI":"10.1124\/mol.113.090183"},{"key":"ref15\/cit15","doi-asserted-by":"publisher","DOI":"10.1042\/bj3280321"},{"key":"ref16\/cit16","doi-asserted-by":"publisher","DOI":"10.1110\/ps.8.12.2672"},{"key":"ref17\/cit17","doi-asserted-by":"crossref","first-page":"1034","DOI":"10.1124\/mol.104.007187","volume":"67","author":"Bagd\u00e1ny M.","year":"2005","journal-title":"Mol. Pharmacol."},{"key":"ref18\/cit18","doi-asserted-by":"publisher","DOI":"10.1110\/ps.03186703"},{"key":"ref19\/cit19","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1097-0134(199711)29:3<321::AID-PROT6>3.0.CO;2-D"},{"key":"ref20\/cit20","doi-asserted-by":"publisher","DOI":"10.1016\/S0041-0101(98)00153-6"},{"key":"ref21\/cit21","doi-asserted-by":"publisher","DOI":"10.1034\/j.1399-3011.2000.00715.x"},{"key":"ref22\/cit22","doi-asserted-by":"publisher","DOI":"10.1124\/mol.112.078006"},{"key":"ref23\/cit23","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M114.561324"},{"key":"ref24\/cit24","doi-asserted-by":"publisher","DOI":"10.1016\/0896-6273(92)90239-A"},{"key":"ref25\/cit25","doi-asserted-by":"publisher","DOI":"10.1016\/0014-5793(82)80820-X"},{"key":"ref26\/cit26","doi-asserted-by":"publisher","DOI":"10.1016\/S0006-3495(02)75251-X"},{"key":"ref27\/cit27","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.272.7.4302"},{"key":"ref28\/cit28","doi-asserted-by":"publisher","DOI":"10.1016\/j.toxicon.2004.03.024"},{"key":"ref29\/cit29","doi-asserted-by":"publisher","DOI":"10.1124\/mol.104.002774"},{"key":"ref30\/cit30","doi-asserted-by":"publisher","DOI":"10.1021\/ci900025n"},{"key":"ref31\/cit31","first-page":"1","volume-title":"Scorpion Venoms","author":"Bartok A.","year":"2014"},{"key":"ref32\/cit32","doi-asserted-by":"publisher","DOI":"10.1093\/molbev\/msu038"},{"key":"ref33\/cit33","doi-asserted-by":"publisher","DOI":"10.1126\/science.280.5360.106"},{"key":"ref34\/cit34","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M802054200"}],"container-title":["Biochemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acs.biochem.6b00139","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,4,14]],"date-time":"2023-04-14T07:01:51Z","timestamp":1681455711000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/acs.biochem.6b00139"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,5,18]]},"references-count":34,"journal-issue":{"issue":"21","published-print":{"date-parts":[[2016,5,31]]}},"alternative-id":["10.1021\/acs.biochem.6b00139"],"URL":"https:\/\/doi.org\/10.1021\/acs.biochem.6b00139","relation":{},"ISSN":["0006-2960","1520-4995"],"issn-type":[{"value":"0006-2960","type":"print"},{"value":"1520-4995","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,5,18]]}}}