{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,13]],"date-time":"2026-05-13T15:13:52Z","timestamp":1778685232493,"version":"3.51.4"},"reference-count":54,"publisher":"American Chemical Society (ACS)","issue":"28","funder":[{"DOI":"10.13039\/501100001405","name":"Tata Institute of Fundamental Research","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001405","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Biochemistry"],"published-print":{"date-parts":[[2018,7,17]]},"DOI":"10.1021\/acs.biochem.8b00504","type":"journal-article","created":{"date-parts":[[2018,6,21]],"date-time":"2018-06-21T22:25:07Z","timestamp":1529619907000},"page":"4206-4213","source":"Crossref","is-referenced-by-count":10,"title":["Spontaneous Fluctuations Can Guide Drug Design Strategies for Structurally Disordered Proteins"],"prefix":"10.1021","volume":"57","author":[{"given":"Barun Kumar","family":"Maity","sequence":"first","affiliation":[{"name":"Department of Chemical Sciences, Tata Institute of Fundamental Research, Homi Bhabha Road, Colaba, Mumbai 400005, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vicky","family":"Vishvakarma","sequence":"additional","affiliation":[{"name":"Department of Chemical Sciences, Tata Institute of Fundamental Research, Homi Bhabha Road, Colaba, Mumbai 400005, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dayana","family":"Surendran","sequence":"additional","affiliation":[{"name":"Department of Chemical Sciences, Tata Institute of Fundamental Research, Homi Bhabha Road, Colaba, Mumbai 400005, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anoop","family":"Rawat","sequence":"additional","affiliation":[{"name":"Department of Chemical Sciences, Tata Institute of Fundamental Research, Homi Bhabha Road, Colaba, Mumbai 400005, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anirban","family":"Das","sequence":"additional","affiliation":[{"name":"Department of Chemical Sciences, Tata Institute of Fundamental Research, Homi Bhabha Road, Colaba, Mumbai 400005, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shreya","family":"Pramanik","sequence":"additional","affiliation":[{"name":"UM-DAE Centre for Excellence in Basic Sciences, University of Mumbai, Kalina, Mumbai 400098, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Najmul","family":"Arfin","sequence":"additional","affiliation":[{"name":"Center for Interdisciplinary Research in Basic Sciences, Jamia Milia Islamia, New Delhi 110025, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6540-7472","authenticated-orcid":true,"given":"Sudipta","family":"Maiti","sequence":"additional","affiliation":[{"name":"Department of Chemical Sciences, Tata Institute of Fundamental Research, Homi Bhabha Road, Colaba, Mumbai 400005, India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"316","published-online":{"date-parts":[[2018,6,21]]},"reference":[{"key":"ref1\/cit1","doi-asserted-by":"publisher","DOI":"10.1038\/nature19323"},{"key":"ref2\/cit2","doi-asserted-by":"publisher","DOI":"10.1038\/nrn3406"},{"key":"ref3\/cit3","doi-asserted-by":"publisher","DOI":"10.7554\/eLife.12977"},{"key":"ref4\/cit4","doi-asserted-by":"publisher","DOI":"10.1038\/nrd.2017.95"},{"key":"ref5\/cit5","doi-asserted-by":"publisher","DOI":"10.1038\/nrm3920"},{"key":"ref6\/cit6","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.R115.692020"},{"key":"ref7\/cit7","doi-asserted-by":"publisher","DOI":"10.1016\/j.jmb.2012.06.019"},{"key":"ref8\/cit8","doi-asserted-by":"publisher","DOI":"10.1038\/nature25762"},{"key":"ref9\/cit9","doi-asserted-by":"publisher","DOI":"10.1016\/j.febslet.2015.07.022"},{"key":"ref10\/cit10","doi-asserted-by":"publisher","DOI":"10.1016\/j.cplett.2017.02.070"},{"key":"ref11\/cit11","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0506723102"},{"key":"ref12\/cit12","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1600749113"},{"key":"ref13\/cit13","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0712179105"},{"key":"ref14\/cit14","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2013.08.035"},{"key":"ref15\/cit15","doi-asserted-by":"publisher","DOI":"10.1017\/S0033583506004173"},{"key":"ref16\/cit16","doi-asserted-by":"publisher","DOI":"10.1126\/science.aao2825"},{"key":"ref17\/cit17","doi-asserted-by":"publisher","DOI":"10.2337\/diabetes.53.6.1509"},{"key":"ref18\/cit18","doi-asserted-by":"publisher","DOI":"10.1210\/er.2007-0037"},{"key":"ref19\/cit19","doi-asserted-by":"publisher","DOI":"10.2337\/diabetes.48.3.491"},{"key":"ref20\/cit20","doi-asserted-by":"publisher","DOI":"10.1111\/j.1742-4658.2006.05367.x"},{"key":"ref21\/cit21","doi-asserted-by":"publisher","DOI":"10.1021\/bi100939a"},{"key":"ref22\/cit22","doi-asserted-by":"publisher","DOI":"10.1155\/2016\/2046327"},{"key":"ref23\/cit23","doi-asserted-by":"publisher","DOI":"10.3389\/fmolb.2015.00039"},{"key":"ref24\/cit24","doi-asserted-by":"publisher","DOI":"10.1016\/j.drudis.2013.04.008"},{"key":"ref25\/cit25","doi-asserted-by":"publisher","DOI":"10.1038\/srep22298"},{"key":"ref26\/cit26","doi-asserted-by":"publisher","DOI":"10.1103\/PhysRevLett.29.705"},{"key":"ref27\/cit27","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.94.22.11753"},{"key":"ref28\/cit28","doi-asserted-by":"publisher","DOI":"10.1002\/cphc.201000722"},{"key":"ref29\/cit29","doi-asserted-by":"publisher","DOI":"10.1038\/nmeth.3475"},{"key":"ref30\/cit30","doi-asserted-by":"publisher","DOI":"10.1021\/jp076971j"},{"key":"ref31\/cit31","doi-asserted-by":"publisher","DOI":"10.1117\/12.909829"},{"key":"ref32\/cit32","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0910860106"},{"key":"ref33\/cit33","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0500127102"},{"key":"ref34\/cit34","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0611503104"},{"key":"ref35\/cit35","doi-asserted-by":"publisher","DOI":"10.1016\/j.abb.2017.05.016"},{"key":"ref36\/cit36","doi-asserted-by":"publisher","DOI":"10.1007\/s10858-017-0155-0"},{"key":"ref37\/cit37","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M611904200"},{"key":"ref38\/cit38","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.96.16.9077"},{"key":"ref39\/cit39","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0808581106"},{"key":"ref40\/cit40","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1620400114"},{"key":"ref41\/cit41","doi-asserted-by":"publisher","DOI":"10.1021\/bi0341410"},{"key":"ref42\/cit42","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbamem.2007.01.022"},{"key":"ref43\/cit43","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1305517110"},{"key":"ref44\/cit44","doi-asserted-by":"publisher","DOI":"10.1021\/la502679t"},{"key":"ref45\/cit45","doi-asserted-by":"publisher","DOI":"10.3389\/fphys.2013.00084"},{"key":"ref46\/cit46","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbamem.2018.03.027"},{"key":"ref47\/cit47","volume-title":"Fluorescence Correlation Spectroscopy: Theory and applications","author":"Rigler R.","year":"2000"},{"key":"ref48\/cit48","doi-asserted-by":"publisher","DOI":"10.1016\/j.bpj.2010.07.020"},{"key":"ref49\/cit49","doi-asserted-by":"publisher","DOI":"10.1038\/nsmb.1437"},{"key":"ref50\/cit50","doi-asserted-by":"publisher","DOI":"10.1111\/j.1747-0285.2005.00318.x"},{"key":"ref51\/cit51","doi-asserted-by":"publisher","DOI":"10.3390\/ijms17060964"},{"key":"ref52\/cit52","doi-asserted-by":"publisher","DOI":"10.1042\/bj20030422"},{"key":"ref53\/cit53","doi-asserted-by":"publisher","DOI":"10.1021\/bi3012274"},{"key":"ref54\/cit54","doi-asserted-by":"publisher","DOI":"10.1021\/bi2015162"}],"container-title":["Biochemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acs.biochem.8b00504","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,4,14]],"date-time":"2023-04-14T19:45:15Z","timestamp":1681501515000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/acs.biochem.8b00504"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,6,21]]},"references-count":54,"journal-issue":{"issue":"28","published-print":{"date-parts":[[2018,7,17]]}},"alternative-id":["10.1021\/acs.biochem.8b00504"],"URL":"https:\/\/doi.org\/10.1021\/acs.biochem.8b00504","relation":{},"ISSN":["0006-2960","1520-4995"],"issn-type":[{"value":"0006-2960","type":"print"},{"value":"1520-4995","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,6,21]]}}}