{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T04:26:43Z","timestamp":1790137603452,"version":"4.0.1"},"reference-count":50,"publisher":"American Chemical Society (ACS)","issue":"27","license":[{"start":{"date-parts":[[2019,6,4]],"date-time":"2019-06-04T00:00:00Z","timestamp":1559606400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2019,6,4]],"date-time":"2019-06-04T00:00:00Z","timestamp":1559606400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2019,6,4]],"date-time":"2019-06-04T00:00:00Z","timestamp":1559606400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-045"}],"funder":[{"DOI":"10.13039\/100000057","name":"National Institute of General Medical Sciences","doi-asserted-by":"publisher","award":["81539"],"award-info":[{"award-number":["81539"]}],"id":[{"id":"10.13039\/100000057","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000057","name":"National Institute of General Medical Sciences","doi-asserted-by":"publisher","award":["121964"],"award-info":[{"award-number":["121964"]}],"id":[{"id":"10.13039\/100000057","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Biochemistry"],"published-print":{"date-parts":[[2019,7,9]]},"DOI":"10.1021\/acs.biochem.9b00184","type":"journal-article","created":{"date-parts":[[2019,6,4]],"date-time":"2019-06-04T17:34:21Z","timestamp":1559669661000},"page":"2996-3004","source":"Crossref","is-referenced-by-count":5,"title":["Rapid Discovery and Characterization of Synthetic Neutralizing Antibodies against Anthrax Edema Toxin"],"prefix":"10.1021","volume":"58","author":[{"given":"Mara","family":"Farcasanu","sequence":"first","affiliation":[{"name":"The Ben May Department for Cancer Research, The University of Chicago, Chicago, Illinois 60637, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrew G.","family":"Wang","sequence":"additional","affiliation":[{"name":"The Ben May Department for Cancer Research, The University of Chicago, Chicago, Illinois 60637, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tomasz","family":"Ucha\u0144ski","sequence":"additional","affiliation":[{"name":"Department of Biochemistry and Molecular Biology, The University of Chicago, Chicago, Illinois 60637, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lucas J.","family":"Bailey","sequence":"additional","affiliation":[{"name":"Department of Biochemistry and Molecular Biology, The University of Chicago, Chicago, Illinois 60637, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiping","family":"Yue","sequence":"additional","affiliation":[{"name":"The Ben May Department for Cancer Research, The University of Chicago, Chicago, Illinois 60637, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhaochun","family":"Chen","sequence":"additional","affiliation":[{"name":"National Institute of Allergy and Infection, National Institutes of Health, Bethesda, Maryland 20892, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaoyang","family":"Wu","sequence":"additional","affiliation":[{"name":"The Ben May Department for Cancer Research, The University of Chicago, Chicago, Illinois 60637, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anthony","family":"Kossiakoff","sequence":"additional","affiliation":[{"name":"Department of Biochemistry and Molecular Biology, The University of Chicago, Chicago, Illinois 60637, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8267-8995","authenticated-orcid":true,"given":"Wei-Jen","family":"Tang","sequence":"additional","affiliation":[{"name":"The Ben May Department for Cancer Research, The University of Chicago, Chicago, Illinois 60637, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2019,6,4]]},"reference":[{"key":"ref1\/cit1","doi-asserted-by":"publisher","DOI":"10.1126\/science.7973702"},{"key":"ref2\/cit2","doi-asserted-by":"publisher","DOI":"10.3201\/eid0810.020353"},{"key":"ref3\/cit3","doi-asserted-by":"publisher","DOI":"10.1016\/j.micinf.2011.08.016"},{"key":"ref4\/cit4","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9440(10)61218-7"},{"key":"ref5\/cit5","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.01781-06"},{"key":"ref6\/cit6","doi-asserted-by":"publisher","DOI":"10.1038\/nature12510"},{"key":"ref7\/cit7","doi-asserted-by":"publisher","DOI":"10.1016\/j.tim.2014.02.012"},{"key":"ref8\/cit8","doi-asserted-by":"publisher","DOI":"10.3201\/eid2002.130687"},{"key":"ref9\/cit9","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.89.21.10277"},{"key":"ref10\/cit10","doi-asserted-by":"crossref","first-page":"1853","DOI":"10.1128\/IAI.67.4.1853-1859.1999","volume":"67","author":"Singh Y.","year":"1999","journal-title":"Infect. Immun."},{"key":"ref11\/cit11","doi-asserted-by":"publisher","DOI":"10.1016\/j.celrep.2013.10.019"},{"key":"ref12\/cit12","doi-asserted-by":"publisher","DOI":"10.1083\/jcb.200312072"},{"key":"ref13\/cit13","doi-asserted-by":"publisher","DOI":"10.1016\/j.pharmthera.2014.12.002"},{"key":"ref14\/cit14","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M302837200"},{"key":"ref15\/cit15","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbrc.2014.06.088"},{"key":"ref16\/cit16","doi-asserted-by":"publisher","DOI":"10.1038\/ncomms13582"},{"key":"ref17\/cit17","doi-asserted-by":"publisher","DOI":"10.1165\/rcmb.2008-0091TR"},{"key":"ref18\/cit18","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0800105105"},{"key":"ref19\/cit19","doi-asserted-by":"publisher","DOI":"10.1084\/jem.20041557"},{"key":"ref20\/cit20","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.174.8.4934"},{"key":"ref21\/cit21","doi-asserted-by":"publisher","DOI":"10.1126\/science.280.5364.734"},{"key":"ref22\/cit22","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa0810603"},{"key":"ref23\/cit23","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M301154200"},{"key":"ref24\/cit24","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0906581106"},{"key":"ref25\/cit25","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M116.749184"},{"key":"ref26\/cit26","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M114.627943"},{"key":"ref27\/cit27","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.01528-06"},{"key":"ref28\/cit28","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-017-14823-w"},{"key":"ref29\/cit29","doi-asserted-by":"publisher","DOI":"10.1016\/j.jmb.2007.08.005"},{"key":"ref30\/cit30","doi-asserted-by":"publisher","DOI":"10.1074\/mcp.O115.052209"},{"key":"ref31\/cit31","doi-asserted-by":"publisher","DOI":"10.1016\/j.ymeth.2012.12.010"},{"key":"ref32\/cit32","doi-asserted-by":"publisher","DOI":"10.1016\/j.jim.2014.10.003"},{"key":"ref33\/cit33","doi-asserted-by":"publisher","DOI":"10.1002\/pro.2888"},{"key":"ref34\/cit34","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.271.46.29211"},{"key":"ref35\/cit35","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M301232200"},{"key":"ref36\/cit36","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.172229899"},{"key":"ref37\/cit37","doi-asserted-by":"publisher","DOI":"10.3390\/toxins7061854"},{"key":"ref38\/cit38","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1036973100"},{"key":"ref39\/cit39","doi-asserted-by":"publisher","DOI":"10.1016\/j.chom.2013.03.001"},{"key":"ref40\/cit40","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbrc.2011.11.108"},{"key":"ref41\/cit41","doi-asserted-by":"publisher","DOI":"10.1016\/j.pharmthera.2013.07.002"},{"key":"ref42\/cit42","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0306552101"},{"key":"ref43\/cit43","doi-asserted-by":"publisher","DOI":"10.1016\/j.chembiol.2004.05.020"},{"key":"ref44\/cit44","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajpath.2011.02.027"},{"key":"ref45\/cit45","doi-asserted-by":"publisher","DOI":"10.1021\/acs.biochem.6b01163"},{"key":"ref46\/cit46","doi-asserted-by":"publisher","DOI":"10.1126\/scitranslmed.3002234"},{"key":"ref47\/cit47","doi-asserted-by":"publisher","DOI":"10.1016\/j.jmb.2017.12.012"},{"key":"ref48\/cit48","doi-asserted-by":"publisher","DOI":"10.7554\/eLife.33572"},{"key":"ref49\/cit49","doi-asserted-by":"publisher","DOI":"10.1110\/ps.034892.108"},{"key":"ref50\/cit50","doi-asserted-by":"publisher","DOI":"10.1080\/19420862.2016.1212149"}],"container-title":["Biochemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acs.biochem.9b00184","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,4,17]],"date-time":"2023-04-17T10:59:41Z","timestamp":1681729181000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/acs.biochem.9b00184"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,6,4]]},"references-count":50,"journal-issue":{"issue":"27","published-print":{"date-parts":[[2019,7,9]]}},"alternative-id":["10.1021\/acs.biochem.9b00184"],"URL":"https:\/\/doi.org\/10.1021\/acs.biochem.9b00184","relation":{},"ISSN":["0006-2960","1520-4995"],"issn-type":[{"value":"0006-2960","type":"print"},{"value":"1520-4995","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,6,4]]}}}