{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,3]],"date-time":"2026-11-03T07:04:36Z","timestamp":1793689476795,"version":"4.5.1"},"reference-count":51,"publisher":"American Chemical Society (ACS)","issue":"1","license":[{"start":{"date-parts":[[2021,12,14]],"date-time":"2021-12-14T00:00:00Z","timestamp":1639440000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2021,12,14]],"date-time":"2021-12-14T00:00:00Z","timestamp":1639440000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2021,12,14]],"date-time":"2021-12-14T00:00:00Z","timestamp":1639440000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-045"}],"funder":[{"DOI":"10.13039\/501100002858","name":"China Postdoctoral Science Foundation","doi-asserted-by":"publisher","award":["2021M690488"],"award-info":[{"award-number":["2021M690488"]}],"id":[{"id":"10.13039\/501100002858","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004829","name":"Department of Science and Technology of Sichuan Province","doi-asserted-by":"publisher","award":["2020YFS0330"],"award-info":[{"award-number":["2020YFS0330"]}],"id":[{"id":"10.13039\/501100004829","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81603309"],"award-info":[{"award-number":["81603309"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Biomacromolecules"],"published-print":{"date-parts":[[2022,1,10]]},"DOI":"10.1021\/acs.biomac.1c01233","type":"journal-article","created":{"date-parts":[[2021,12,14]],"date-time":"2021-12-14T12:34:41Z","timestamp":1639485281000},"page":"210-225","source":"Crossref","is-referenced-by-count":51,"title":["Preparation of Oral Core\u2013Shell Zein Nanoparticles to Improve the Bioavailability of Glycyrrhizic Acid for the Treatment of Ulcerative Colitis"],"prefix":"10.1021","volume":"23","author":[{"given":"Anxin","family":"Wu","sequence":"first","affiliation":[{"name":"College Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu 611137, People\u2019s Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chonghao","family":"Chen","sequence":"additional","affiliation":[{"name":"College Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu 611137, People\u2019s Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jing","family":"Lu","sequence":"additional","affiliation":[{"name":"College Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu 611137, People\u2019s Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiayi","family":"Sun","sequence":"additional","affiliation":[{"name":"College Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu 611137, People\u2019s Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Meng","family":"Xiao","sequence":"additional","affiliation":[{"name":"College Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu 611137, People\u2019s Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xuan","family":"Yue","sequence":"additional","affiliation":[{"name":"College Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu 611137, People\u2019s Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ping","family":"Zhou","sequence":"additional","affiliation":[{"name":"College Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu 611137, People\u2019s Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shiyi","family":"Zhao","sequence":"additional","affiliation":[{"name":"College Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu 611137, People\u2019s Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guofeng","family":"Zhong","sequence":"additional","affiliation":[{"name":"College Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu 611137, People\u2019s Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chi","family":"Huang","sequence":"additional","affiliation":[{"name":"College Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu 611137, People\u2019s Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7065-2229","authenticated-orcid":true,"given":"Yan","family":"Qu","sequence":"additional","affiliation":[{"name":"College Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu 611137, People\u2019s Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chen","family":"Zhang","sequence":"additional","affiliation":[{"name":"College Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu 611137, People\u2019s Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2021,12,14]]},"reference":[{"key":"ref1\/cit1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejps.2020.105280"},{"key":"ref2\/cit2","doi-asserted-by":"publisher","DOI":"10.1016\/j.foodchem.2020.127241"},{"key":"ref3\/cit3","doi-asserted-by":"publisher","DOI":"10.1016\/j.jconrel.2020.10.042"},{"key":"ref4\/cit4","doi-asserted-by":"publisher","DOI":"10.1021\/acssuschemeng.8b01613"},{"key":"ref5\/cit5","doi-asserted-by":"publisher","DOI":"10.1002\/advs.202101619"},{"key":"ref6\/cit6","doi-asserted-by":"publisher","DOI":"10.1038\/s41563-019-0462-9"},{"key":"ref7\/cit7","doi-asserted-by":"publisher","DOI":"10.1016\/j.jconrel.2020.09.008"},{"key":"ref8\/cit8","doi-asserted-by":"publisher","DOI":"10.1016\/j.fct.2020.111628"},{"key":"ref9\/cit9","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijpharm.2021.120546"},{"key":"ref10\/cit10","doi-asserted-by":"publisher","DOI":"10.1016\/j.fbio.2021.101089"},{"key":"ref11\/cit11","doi-asserted-by":"publisher","DOI":"10.1021\/acs.biomac.7b00728"},{"key":"ref12\/cit12","doi-asserted-by":"publisher","DOI":"10.1016\/j.jconrel.2018.08.004"},{"key":"ref13\/cit13","doi-asserted-by":"publisher","DOI":"10.1016\/j.cbi.2020.109089"},{"key":"ref14\/cit14","doi-asserted-by":"publisher","DOI":"10.1016\/j.carbpol.2020.116325"},{"key":"ref15\/cit15","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijbiomac.2020.09.214"},{"key":"ref16\/cit16","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijpharm.2018.12.021"},{"key":"ref17\/cit17","doi-asserted-by":"publisher","DOI":"10.1039\/D0FO02536D"},{"key":"ref18\/cit18","doi-asserted-by":"publisher","DOI":"10.1007\/s11051-017-3763-4"},{"key":"ref19\/cit19","doi-asserted-by":"publisher","DOI":"10.1016\/j.foodhyd.2021.107082"},{"key":"ref20\/cit20","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijpharm.2019.01.066"},{"key":"ref21\/cit21","doi-asserted-by":"publisher","DOI":"10.1016\/j.nano.2020.102277"},{"key":"ref22\/cit22","doi-asserted-by":"publisher","DOI":"10.1016\/j.actbio.2017.04.017"},{"key":"ref23\/cit23","doi-asserted-by":"publisher","DOI":"10.1093\/ecco-jcc\/jjx115"},{"key":"ref24\/cit24","doi-asserted-by":"publisher","DOI":"10.1016\/j.nano.2020.102173"},{"key":"ref25\/cit25","doi-asserted-by":"publisher","DOI":"10.1016\/j.lfs.2020.118555"},{"key":"ref26\/cit26","doi-asserted-by":"publisher","DOI":"10.1016\/j.foodhyd.2021.106858"},{"key":"ref27\/cit27","doi-asserted-by":"publisher","DOI":"10.1016\/j.jconrel.2019.10.054"},{"key":"ref28\/cit28","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejpb.2020.08.017"},{"key":"ref29\/cit29","doi-asserted-by":"publisher","DOI":"10.1021\/ic500609g"},{"key":"ref30\/cit30","doi-asserted-by":"publisher","DOI":"10.1021\/acs.iecr.7b01632"},{"key":"ref31\/cit31","doi-asserted-by":"publisher","DOI":"10.1016\/j.foodres.2021.110425"},{"key":"ref32\/cit32","doi-asserted-by":"publisher","DOI":"10.1021\/acs.biomac.1c00653"},{"key":"ref33\/cit33","doi-asserted-by":"publisher","DOI":"10.1016\/j.jconrel.2017.01.035"},{"key":"ref34\/cit34","doi-asserted-by":"publisher","DOI":"10.1039\/C8FO01614C"},{"key":"ref35\/cit35","doi-asserted-by":"publisher","DOI":"10.1016\/j.carbpol.2020.115981"},{"key":"ref36\/cit36","doi-asserted-by":"publisher","DOI":"10.1016\/j.apsb.2020.07.019"},{"key":"ref37\/cit37","doi-asserted-by":"publisher","DOI":"10.1016\/j.jconrel.2018.04.050"},{"key":"ref38\/cit38","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijpharm.2019.05.025"},{"key":"ref39\/cit39","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijpharm.2020.119101"},{"key":"ref40\/cit40","doi-asserted-by":"publisher","DOI":"10.1016\/j.foodhyd.2019.105334"},{"key":"ref41\/cit41","doi-asserted-by":"publisher","DOI":"10.1016\/j.carbpol.2020.116660"},{"key":"ref42\/cit42","doi-asserted-by":"publisher","DOI":"10.1016\/j.carbpol.2020.116193"},{"key":"ref43\/cit43","doi-asserted-by":"publisher","DOI":"10.1002\/adfm.201808197"},{"key":"ref44\/cit44","doi-asserted-by":"publisher","DOI":"10.1016\/j.transci.2020.102930"},{"key":"ref45\/cit45","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijpharm.2020.119617"},{"key":"ref46\/cit46","doi-asserted-by":"publisher","DOI":"10.1016\/j.ebiom.2019.02.027"},{"key":"ref47\/cit47","doi-asserted-by":"publisher","DOI":"10.7150\/thno.15710"},{"key":"ref48\/cit48","doi-asserted-by":"publisher","DOI":"10.1021\/acsami.1c09804"},{"key":"ref49\/cit49","doi-asserted-by":"publisher","DOI":"10.1016\/j.bioorg.2020.104130"},{"key":"ref50\/cit50","doi-asserted-by":"publisher","DOI":"10.1016\/j.taap.2020.115075"},{"key":"ref51\/cit51","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcmgh.2020.01.005"}],"container-title":["Biomacromolecules"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acs.biomac.1c01233","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,4,27]],"date-time":"2023-04-27T16:27:19Z","timestamp":1682612839000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/acs.biomac.1c01233"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,12,14]]},"references-count":51,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2022,1,10]]}},"alternative-id":["10.1021\/acs.biomac.1c01233"],"URL":"https:\/\/doi.org\/10.1021\/acs.biomac.1c01233","relation":{},"ISSN":["1525-7797","1526-4602"],"issn-type":[{"value":"1525-7797","type":"print"},{"value":"1526-4602","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,12,14]]}}}