{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,24]],"date-time":"2026-08-24T19:04:32Z","timestamp":1787598272687,"version":"build-2736575974"},"reference-count":73,"publisher":"American Chemical Society (ACS)","issue":"4","license":[{"start":{"date-parts":[[2023,3,29]],"date-time":"2023-03-29T00:00:00Z","timestamp":1680048000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2023,3,29]],"date-time":"2023-03-29T00:00:00Z","timestamp":1680048000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2023,3,29]],"date-time":"2023-03-29T00:00:00Z","timestamp":1680048000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-045"}],"funder":[{"DOI":"10.13039\/100000774","name":"Defense Threat Reduction Agency","doi-asserted-by":"publisher","award":["HDTRA118-1-0029"],"award-info":[{"award-number":["HDTRA118-1-0029"]}],"id":[{"id":"10.13039\/100000774","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Biomacromolecules"],"published-print":{"date-parts":[[2023,4,10]]},"DOI":"10.1021\/acs.biomac.3c00144","type":"journal-article","created":{"date-parts":[[2023,3,29]],"date-time":"2023-03-29T19:29:05Z","timestamp":1680118145000},"page":"1934-1941","source":"Crossref","is-referenced-by-count":6,"title":["Modular Catalysis: Aptamer Enhancement of Enzyme Kinetics in a Nanoparticle Reactor"],"prefix":"10.1021","volume":"24","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6507-6848","authenticated-orcid":true,"given":"Brea A.","family":"Manuel","sequence":"first","affiliation":[{"name":"Department of Chemistry, Emory University, Atlanta, Georgia 30322, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0743-8131","authenticated-orcid":true,"given":"Soumen","family":"Das","sequence":"additional","affiliation":[{"name":"School of Chemistry and Biochemistry, Georgia Institute of Technology, 901 Atlantic Drive, Atlanta, Georgia 30306, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aimee","family":"Sanford","sequence":"additional","affiliation":[{"name":"Department of Chemistry, Emory University, Atlanta, Georgia 30322, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matthew C.","family":"Jenkins","sequence":"additional","affiliation":[{"name":"School of Chemistry and Biochemistry, Georgia Institute of Technology, 901 Atlantic Drive, Atlanta, Georgia 30306, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8247-3108","authenticated-orcid":true,"given":"M. G.","family":"Finn","sequence":"additional","affiliation":[{"name":"School of Chemistry and Biochemistry, Georgia Institute of Technology, 901 Atlantic Drive, Atlanta, Georgia 30306, United States"},{"name":"School of Biological Sciences, Georgia Institute of Technology, 901 Atlantic Drive, Atlanta, Georgia 30306, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7691-8526","authenticated-orcid":true,"given":"Jennifer M.","family":"Heemstra","sequence":"additional","affiliation":[{"name":"Department of Chemistry, Emory University, Atlanta, Georgia 30322, United States"},{"name":"Washington University in St. Louis, One Brookings Drive, St. Louis, Missouri 63130, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2023,3,29]]},"reference":[{"key":"ref1\/cit1","doi-asserted-by":"crossref","DOI":"10.1088\/978-0-7503-1299-8","volume-title":"Introduction to Pharmaceutical Biotechnology","volume":"2","author":"Bhatia S.","year":"2018"},{"key":"ref2\/cit2","doi-asserted-by":"publisher","DOI":"10.3390\/ijms22179181"},{"key":"ref3\/cit3","doi-asserted-by":"crossref","unstructured":"Kunamneni, A.; Ogaugwu, C.; Goli, D. InEnzyme Hum. Anim. Nutr.; Nunes, C. S., Kumar, V., Eds. Academic Press: 2018; Chapter 15, pp 301\u2013312.","DOI":"10.1016\/B978-0-12-805419-2.00015-0"},{"key":"ref4\/cit4","doi-asserted-by":"publisher","DOI":"10.1016\/j.tibtech.2009.10.001"},{"key":"ref5\/cit5","doi-asserted-by":"publisher","DOI":"10.1093\/protein\/gzq025"},{"key":"ref6\/cit6","doi-asserted-by":"publisher","DOI":"10.1038\/nchembio.203"},{"key":"ref7\/cit7","doi-asserted-by":"publisher","DOI":"10.1111\/j.1751-7915.2011.00280.x"},{"key":"ref8\/cit8","doi-asserted-by":"publisher","DOI":"10.1039\/c2lc21035e"},{"key":"ref9\/cit9","doi-asserted-by":"publisher","DOI":"10.1002\/pro.2950"},{"key":"ref10\/cit10","doi-asserted-by":"publisher","DOI":"10.1021\/cr0301191"},{"key":"ref11\/cit11","doi-asserted-by":"publisher","DOI":"10.1016\/j.enzmictec.2021.109864"},{"key":"ref12\/cit12","doi-asserted-by":"publisher","DOI":"10.1021\/acscatal.8b04921"},{"key":"ref13\/cit13","doi-asserted-by":"publisher","DOI":"10.1021\/bm060166d"},{"key":"ref14\/cit14","doi-asserted-by":"publisher","DOI":"10.1039\/b604689d"},{"key":"ref15\/cit15","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijbiomac.2018.05.227"},{"key":"ref16\/cit16","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jafc.6b05003"},{"key":"ref17\/cit17","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijbiomac.2012.01.017"},{"key":"ref18\/cit18","doi-asserted-by":"publisher","DOI":"10.1016\/j.cej.2017.04.022"},{"key":"ref19\/cit19","doi-asserted-by":"publisher","DOI":"10.1002\/bit.25536"},{"key":"ref20\/cit20","doi-asserted-by":"publisher","DOI":"10.1039\/C6CY00783J"},{"key":"ref21\/cit21","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijbiomac.2019.03.189"},{"key":"ref22\/cit22","doi-asserted-by":"publisher","DOI":"10.1016\/j.procbio.2006.05.028"},{"key":"ref23\/cit23","doi-asserted-by":"publisher","DOI":"10.1016\/j.colsurfb.2016.06.008"},{"key":"ref24\/cit24","doi-asserted-by":"publisher","DOI":"10.1002\/smll.200500376"},{"key":"ref25\/cit25","doi-asserted-by":"publisher","DOI":"10.1002\/bit.21447"},{"key":"ref26\/cit26","doi-asserted-by":"publisher","DOI":"10.1038\/nbt931"},{"key":"ref27\/cit27","doi-asserted-by":"publisher","DOI":"10.1002\/chem.201503613"},{"key":"ref28\/cit28","doi-asserted-by":"publisher","DOI":"10.1002\/mabi.200600140"},{"key":"ref29\/cit29","doi-asserted-by":"publisher","DOI":"10.1016\/j.chemosphere.2015.07.020"},{"key":"ref30\/cit30","doi-asserted-by":"publisher","DOI":"10.1039\/b404586f"},{"key":"ref31\/cit31","doi-asserted-by":"publisher","DOI":"10.1021\/la1033492"},{"key":"ref32\/cit32","doi-asserted-by":"publisher","DOI":"10.1021\/nn300545z"},{"key":"ref33\/cit33","doi-asserted-by":"publisher","DOI":"10.1021\/ja045308v"},{"key":"ref34\/cit34","doi-asserted-by":"publisher","DOI":"10.1021\/acs.biomac.7b00202"},{"key":"ref35\/cit35","doi-asserted-by":"publisher","DOI":"10.1021\/acs.biomac.6b00233"},{"key":"ref36\/cit36","doi-asserted-by":"publisher","DOI":"10.1039\/C4TB01803F"},{"key":"ref37\/cit37","doi-asserted-by":"publisher","DOI":"10.1039\/C4TB01701C"},{"key":"ref38\/cit38","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijbiomac.2019.02.131"},{"key":"ref39\/cit39","doi-asserted-by":"publisher","DOI":"10.1038\/ncomms10619"},{"key":"ref40\/cit40","doi-asserted-by":"publisher","DOI":"10.1039\/C8NR07294A"},{"key":"ref41\/cit41","doi-asserted-by":"publisher","DOI":"10.1021\/cm701959e"},{"key":"ref42\/cit42","doi-asserted-by":"publisher","DOI":"10.1016\/j.chemosphere.2013.02.071"},{"key":"ref43\/cit43","doi-asserted-by":"publisher","DOI":"10.1007\/BF00251225"},{"key":"ref44\/cit44","doi-asserted-by":"publisher","DOI":"10.1038\/s41589-021-00801-x"},{"key":"ref45\/cit45","doi-asserted-by":"publisher","DOI":"10.1002\/cbic.201600224"},{"key":"ref46\/cit46","doi-asserted-by":"publisher","DOI":"10.1002\/anie.201005243"},{"key":"ref47\/cit47","doi-asserted-by":"publisher","DOI":"10.1021\/acs.biochem.0c00435"},{"key":"ref48\/cit48","doi-asserted-by":"publisher","DOI":"10.1021\/acs.biomac.0c00362"},{"key":"ref49\/cit49","doi-asserted-by":"publisher","DOI":"10.1021\/bp070392e"},{"key":"ref50\/cit50","doi-asserted-by":"publisher","DOI":"10.1021\/acs.biomac.0c00824"},{"key":"ref51\/cit51","doi-asserted-by":"publisher","DOI":"10.1021\/cb4006529"},{"key":"ref52\/cit52","doi-asserted-by":"publisher","DOI":"10.1039\/C5NR08734A"},{"key":"ref53\/cit53","doi-asserted-by":"publisher","DOI":"10.1038\/nnano.2012.264"},{"key":"ref54\/cit54","doi-asserted-by":"publisher","DOI":"10.1016\/j.copbio.2016.11.020"},{"key":"ref55\/cit55","doi-asserted-by":"publisher","DOI":"10.1039\/D2SC00117A"},{"key":"ref56\/cit56","doi-asserted-by":"publisher","DOI":"10.1038\/346818a0"},{"key":"ref57\/cit57","doi-asserted-by":"publisher","DOI":"10.1021\/acs.biomac.8b00885"},{"key":"ref58\/cit58","doi-asserted-by":"publisher","DOI":"10.1021\/bc00035a013"},{"key":"ref59\/cit59","doi-asserted-by":"publisher","DOI":"10.1021\/nn201397z"},{"key":"ref60\/cit60","doi-asserted-by":"publisher","DOI":"10.1006\/jmbi.1993.1616"},{"key":"ref61\/cit61","doi-asserted-by":"publisher","DOI":"10.1021\/ac000725l"},{"key":"ref62\/cit62","doi-asserted-by":"publisher","DOI":"10.1021\/ja031790q"},{"key":"ref63\/cit63","doi-asserted-by":"publisher","DOI":"10.1021\/bc070006e"},{"key":"ref64\/cit64","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbrc.2011.02.122"},{"key":"ref65\/cit65","doi-asserted-by":"publisher","DOI":"10.1002\/ijc.28482"},{"key":"ref66\/cit66","doi-asserted-by":"publisher","DOI":"10.1021\/ac503360n"},{"key":"ref67\/cit67","doi-asserted-by":"publisher","DOI":"10.1021\/ja0038171"},{"key":"ref68\/cit68","doi-asserted-by":"publisher","DOI":"10.1002\/cbic.201600431"},{"key":"ref69\/cit69","doi-asserted-by":"publisher","DOI":"10.1021\/nn302183h"},{"key":"ref70\/cit70","doi-asserted-by":"publisher","DOI":"10.1002\/bit.23191"},{"key":"ref71\/cit71","doi-asserted-by":"publisher","DOI":"10.1021\/acs.analchem.2c00422"},{"key":"ref72\/cit72","doi-asserted-by":"publisher","DOI":"10.1002\/anie.202111687"},{"key":"ref73\/cit73","doi-asserted-by":"publisher","DOI":"10.1038\/s41929-018-0053-1"}],"container-title":["Biomacromolecules"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acs.biomac.3c00144","content-type":"application\/pdf","content-version":"vor","intended-application":"unspecified"},{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acs.biomac.3c00144","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,12,9]],"date-time":"2023-12-09T22:01:34Z","timestamp":1702159294000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/acs.biomac.3c00144"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,3,29]]},"references-count":73,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2023,4,10]]}},"alternative-id":["10.1021\/acs.biomac.3c00144"],"URL":"https:\/\/doi.org\/10.1021\/acs.biomac.3c00144","relation":{},"ISSN":["1525-7797","1526-4602"],"issn-type":[{"value":"1525-7797","type":"print"},{"value":"1526-4602","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,3,29]]}}}