{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T04:06:35Z","timestamp":1792037195324,"version":"4.4.0"},"reference-count":272,"publisher":"American Chemical Society (ACS)","issue":"10","license":[{"start":{"date-parts":[[2024,9,11]],"date-time":"2024-09-11T00:00:00Z","timestamp":1726012800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2024,9,11]],"date-time":"2024-09-11T00:00:00Z","timestamp":1726012800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2024,9,11]],"date-time":"2024-09-11T00:00:00Z","timestamp":1726012800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-045"}],"funder":[{"DOI":"10.13039\/501100006407","name":"Natural Science Foundation of Henan Province","doi-asserted-by":"publisher","award":["242300421089"],"award-info":[{"award-number":["242300421089"]}],"id":[{"id":"10.13039\/501100006407","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100014208","name":"People's Government of Henan Province","doi-asserted-by":"publisher","award":["232301420064"],"award-info":[{"award-number":["232301420064"]}],"id":[{"id":"10.13039\/501100014208","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["32271463"],"award-info":[{"award-number":["32271463"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["52073079"],"award-info":[{"award-number":["52073079"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Henan University Double First Class Foundation"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Biomacromolecules"],"published-print":{"date-parts":[[2024,10,14]]},"DOI":"10.1021\/acs.biomac.4c00722","type":"journal-article","created":{"date-parts":[[2024,9,11]],"date-time":"2024-09-11T13:16:17Z","timestamp":1726060577000},"page":"6250-6282","source":"Crossref","is-referenced-by-count":51,"title":["Stimuli-Responsive Polymeric Nanocarriers Accelerate On-Demand Drug Release to Combat Glioblastoma"],"prefix":"10.1021","volume":"25","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9995-6912","authenticated-orcid":true,"given":"Muhammad","family":"Ismail","sequence":"first","affiliation":[{"name":"Department of Radiotherapy and Translational Medicine Center, Huaihe Hospital of Henan University, Henan University, Kaifeng, Henan 475000, China"},{"name":"Henan-Macquarie University Joint Centre for Biomedical Innovation, Henan Key Laboratory of Brain Targeted Bio-nanomedicine, School of Life Sciences, Henan University, Kaifeng, Henan 475004, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yibin","family":"Wang","sequence":"additional","affiliation":[{"name":"Henan-Macquarie University Joint Centre for Biomedical Innovation, Henan Key Laboratory of Brain Targeted Bio-nanomedicine, School of Life Sciences, Henan University, Kaifeng, Henan 475004, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yundong","family":"Li","sequence":"additional","affiliation":[{"name":"Henan-Macquarie University Joint Centre for Biomedical Innovation, Henan Key Laboratory of Brain Targeted Bio-nanomedicine, School of Life Sciences, Henan University, Kaifeng, Henan 475004, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiayi","family":"Liu","sequence":"additional","affiliation":[{"name":"Henan-Macquarie University Joint Centre for Biomedical Innovation, Henan Key Laboratory of Brain Targeted Bio-nanomedicine, School of Life Sciences, Henan University, Kaifeng, Henan 475004, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2932-1062","authenticated-orcid":true,"given":"Meng","family":"Zheng","sequence":"additional","affiliation":[{"name":"Department of Radiotherapy and Translational Medicine Center, Huaihe Hospital of Henan University, Henan University, Kaifeng, Henan 475000, China"},{"name":"Henan-Macquarie University Joint Centre for Biomedical Innovation, Henan Key Laboratory of Brain Targeted Bio-nanomedicine, School of Life Sciences, Henan University, Kaifeng, Henan 475004, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2307-1376","authenticated-orcid":true,"given":"Yan","family":"Zou","sequence":"additional","affiliation":[{"name":"Department of Radiotherapy and Translational Medicine Center, Huaihe Hospital of Henan University, Henan University, Kaifeng, Henan 475000, China"},{"name":"Henan-Macquarie University Joint Centre for Biomedical Innovation, Henan Key Laboratory of Brain Targeted Bio-nanomedicine, School of Life Sciences, Henan University, Kaifeng, Henan 475004, China"},{"name":"Macquarie Medical School, Faculty of Medicine, Health and Human Sciences, Macquarie University, Sydney, New South Wales 2109, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2024,9,11]]},"reference":[{"key":"ref1\/cit1","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp-2020-325334"},{"key":"ref2\/cit2","doi-asserted-by":"publisher","DOI":"10.1002\/EXP.20230177"},{"key":"ref3\/cit3","doi-asserted-by":"publisher","DOI":"10.1038\/s41582-022-00621-0"},{"key":"ref4\/cit4","doi-asserted-by":"publisher","DOI":"10.1016\/j.addr.2019.11.009"},{"key":"ref5\/cit5","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2022.121608"},{"key":"ref6\/cit6","doi-asserted-by":"publisher","DOI":"10.1016\/j.addr.2023.114773"},{"key":"ref7\/cit7","doi-asserted-by":"publisher","DOI":"10.1007\/s40820-023-01018-4"},{"key":"ref8\/cit8","doi-asserted-by":"publisher","DOI":"10.1021\/acsnano.3c06019"},{"key":"ref9\/cit9","doi-asserted-by":"publisher","DOI":"10.1002\/adhm.202302902"},{"key":"ref10\/cit10","doi-asserted-by":"publisher","DOI":"10.1002\/adhm.202304331"},{"key":"ref11\/cit11","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-020-19225-7"},{"key":"ref12\/cit12","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-023-37328-9"},{"key":"ref13\/cit13","doi-asserted-by":"publisher","DOI":"10.1002\/adfm.202102274"},{"key":"ref14\/cit14","doi-asserted-by":"publisher","DOI":"10.2147\/IJN.S414736"},{"key":"ref15\/cit15","doi-asserted-by":"publisher","DOI":"10.20892\/j.issn.2095-3941.2022.0761"},{"key":"ref16\/cit16","doi-asserted-by":"publisher","DOI":"10.1186\/1475-2867-13-89"},{"key":"ref17\/cit17","doi-asserted-by":"publisher","DOI":"10.2217\/nnm.13.212"},{"key":"ref18\/cit18","doi-asserted-by":"publisher","DOI":"10.1002\/advs.202103836"},{"key":"ref19\/cit19","doi-asserted-by":"publisher","DOI":"10.1016\/j.actbio.2019.09.009"},{"key":"ref20\/cit20","doi-asserted-by":"publisher","DOI":"10.3390\/pharmaceutics14102243"},{"key":"ref21\/cit21","doi-asserted-by":"publisher","DOI":"10.1016\/j.cej.2024.149410"},{"key":"ref22\/cit22","doi-asserted-by":"publisher","DOI":"10.1039\/C6PY01872F"},{"key":"ref23\/cit23","doi-asserted-by":"publisher","DOI":"10.1016\/j.molliq.2022.120628"},{"key":"ref24\/cit24","doi-asserted-by":"publisher","DOI":"10.1158\/1078-0432.CCR-20-0591"},{"key":"ref25\/cit25","doi-asserted-by":"publisher","DOI":"10.1002\/adhm.202202147"},{"key":"ref26\/cit26","doi-asserted-by":"publisher","DOI":"10.1021\/bc060401p"},{"key":"ref27\/cit27","doi-asserted-by":"publisher","DOI":"10.1021\/bc0498166"},{"key":"ref28\/cit28","doi-asserted-by":"publisher","DOI":"10.1021\/acsnano.1c00364"},{"key":"ref29\/cit29","doi-asserted-by":"publisher","DOI":"10.1021\/ja071090b"},{"key":"ref30\/cit30","doi-asserted-by":"publisher","DOI":"10.1021\/acsnano.0c03386"},{"key":"ref31\/cit31","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2020.120463"},{"key":"ref32\/cit32","doi-asserted-by":"publisher","DOI":"10.1002\/advs.202305217"},{"key":"ref33\/cit33","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijbiomac.2023.129181"},{"key":"ref34\/cit34","doi-asserted-by":"publisher","DOI":"10.1002\/adma.201803717"},{"key":"ref35\/cit35","doi-asserted-by":"publisher","DOI":"10.1002\/adma.202203958"},{"key":"ref36\/cit36","doi-asserted-by":"publisher","DOI":"10.1002\/adtp.202200095"},{"key":"ref37\/cit37","doi-asserted-by":"publisher","DOI":"10.1021\/acsnano.2c00320"},{"key":"ref38\/cit38","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2022.121760"},{"key":"ref39\/cit39","doi-asserted-by":"publisher","DOI":"10.1002\/EXP.20210274"},{"key":"ref40\/cit40","doi-asserted-by":"publisher","DOI":"10.1002\/adma.201903759"},{"key":"ref41\/cit41","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0703778104"},{"key":"ref42\/cit42","doi-asserted-by":"publisher","DOI":"10.1021\/acsnano.0c09115"},{"key":"ref43\/cit43","doi-asserted-by":"publisher","DOI":"10.1016\/j.nantod.2023.101790"},{"key":"ref44\/cit44","doi-asserted-by":"publisher","DOI":"10.1002\/adfm.202209239"},{"key":"ref45\/cit45","doi-asserted-by":"publisher","DOI":"10.1021\/acs.nanolett.9b04683"},{"key":"ref46\/cit46","doi-asserted-by":"publisher","DOI":"10.1016\/j.matdes.2022.111290"},{"key":"ref47\/cit47","doi-asserted-by":"publisher","DOI":"10.1039\/C4CC04056B"},{"key":"ref48\/cit48","doi-asserted-by":"publisher","DOI":"10.1021\/acsami.3c03001"},{"key":"ref49\/cit49","doi-asserted-by":"publisher","DOI":"10.1002\/smll.202300029"},{"key":"ref50\/cit50","doi-asserted-by":"publisher","DOI":"10.7554\/eLife.36158"},{"key":"ref51\/cit51","doi-asserted-by":"publisher","DOI":"10.1016\/j.molcel.2010.01.017"},{"key":"ref52\/cit52","doi-asserted-by":"publisher","DOI":"10.1002\/adma.201503662"},{"key":"ref53\/cit53","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcis.2018.12.035"},{"key":"ref54\/cit54","doi-asserted-by":"publisher","DOI":"10.1007\/s12274-022-4739-y"},{"key":"ref55\/cit55","doi-asserted-by":"publisher","DOI":"10.1002\/smll.202207898"},{"key":"ref56\/cit56","doi-asserted-by":"publisher","DOI":"10.1021\/acs.biomac.1c01103"},{"key":"ref57\/cit57","doi-asserted-by":"publisher","DOI":"10.3390\/nano11112892"},{"key":"ref58\/cit58","doi-asserted-by":"publisher","DOI":"10.1002\/adfm.202209216"},{"key":"ref59\/cit59","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-023-37872-4"},{"key":"ref60\/cit60","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-024-44963-3"},{"key":"ref61\/cit61","doi-asserted-by":"publisher","DOI":"10.1002\/adma.202104779"},{"key":"ref62\/cit62","doi-asserted-by":"publisher","DOI":"10.1021\/acsnano.3c03378"},{"key":"ref63\/cit63","doi-asserted-by":"publisher","DOI":"10.1016\/j.apsb.2017.09.008"},{"key":"ref64\/cit64","doi-asserted-by":"publisher","DOI":"10.1002\/adma.201800316"},{"key":"ref65\/cit65","doi-asserted-by":"publisher","DOI":"10.1002\/adma.202000416"},{"key":"ref66\/cit66","doi-asserted-by":"publisher","DOI":"10.1126\/sciadv.abm8011"},{"key":"ref67\/cit67","doi-asserted-by":"publisher","DOI":"10.1007\/s10118-022-2695-3"},{"key":"ref68\/cit68","doi-asserted-by":"publisher","DOI":"10.1002\/path.4255"},{"key":"ref69\/cit69","doi-asserted-by":"publisher","DOI":"10.1016\/j.redox.2018.101084"},{"key":"ref70\/cit70","doi-asserted-by":"publisher","DOI":"10.1038\/cddis.2016.105"},{"key":"ref71\/cit71","doi-asserted-by":"publisher","DOI":"10.1007\/s40820-019-0347-0"},{"key":"ref72\/cit72","doi-asserted-by":"publisher","DOI":"10.1002\/adma.201705054"},{"key":"ref73\/cit73","doi-asserted-by":"publisher","DOI":"10.1002\/adma.201903277"},{"key":"ref74\/cit74","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2021.121036"},{"key":"ref75\/cit75","doi-asserted-by":"publisher","DOI":"10.1016\/j.jconrel.2024.04.043"},{"key":"ref76\/cit76","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-023-40280-3"},{"key":"ref77\/cit77","doi-asserted-by":"publisher","DOI":"10.1016\/j.nantod.2020.100969"},{"key":"ref78\/cit78","doi-asserted-by":"publisher","DOI":"10.1007\/s12274-021-3686-3"},{"key":"ref79\/cit79","doi-asserted-by":"publisher","DOI":"10.3389\/fphar.2020.00574"},{"key":"ref80\/cit80","doi-asserted-by":"publisher","DOI":"10.1039\/D2NR00436D"},{"key":"ref81\/cit81","doi-asserted-by":"publisher","DOI":"10.1016\/j.actbio.2021.02.030"},{"key":"ref82\/cit82","doi-asserted-by":"publisher","DOI":"10.1021\/cr5004634"},{"key":"ref83\/cit83","doi-asserted-by":"publisher","DOI":"10.1038\/nm0512-636b"},{"key":"ref84\/cit84","doi-asserted-by":"publisher","DOI":"10.1038\/onc.2009.441"},{"key":"ref85\/cit85","doi-asserted-by":"publisher","DOI":"10.1158\/1078-0432.CCR-20-3580"},{"key":"ref86\/cit86","doi-asserted-by":"publisher","DOI":"10.1002\/adfm.202312197"},{"key":"ref87\/cit87","doi-asserted-by":"publisher","DOI":"10.1016\/j.jconrel.2019.12.041"},{"key":"ref88\/cit88","doi-asserted-by":"publisher","DOI":"10.7150\/thno.26225"},{"key":"ref89\/cit89","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2022.121599"},{"key":"ref90\/cit90","doi-asserted-by":"publisher","DOI":"10.1039\/D2BM00189F"},{"key":"ref91\/cit91","doi-asserted-by":"publisher","DOI":"10.1002\/adfm.201703967"},{"key":"ref92\/cit92","doi-asserted-by":"publisher","DOI":"10.1016\/j.cej.2020.127359"},{"key":"ref93\/cit93","doi-asserted-by":"publisher","DOI":"10.1002\/adma.201908435"},{"key":"ref94\/cit94","doi-asserted-by":"publisher","DOI":"10.1021\/acsnano.2c05341"},{"key":"ref95\/cit95","doi-asserted-by":"publisher","DOI":"10.1002\/anie.202213578"},{"key":"ref96\/cit96","doi-asserted-by":"publisher","DOI":"10.1016\/j.canlet.2020.05.032"},{"key":"ref97\/cit97","doi-asserted-by":"publisher","DOI":"10.1021\/acsabm.1c00847"},{"key":"ref98\/cit98","doi-asserted-by":"publisher","DOI":"10.1021\/acsabm.0c01336"},{"key":"ref99\/cit99","doi-asserted-by":"publisher","DOI":"10.1021\/acsabm.2c00015"},{"key":"ref100\/cit100","doi-asserted-by":"publisher","DOI":"10.1186\/s12951-023-01960-w"},{"key":"ref101\/cit101","doi-asserted-by":"publisher","DOI":"10.1039\/C7CS00663B"},{"key":"ref102\/cit102","doi-asserted-by":"publisher","DOI":"10.1039\/c2cs35103j"},{"key":"ref103\/cit103","doi-asserted-by":"publisher","DOI":"10.1016\/j.jconrel.2019.07.004"},{"key":"ref104\/cit104","doi-asserted-by":"publisher","DOI":"10.1016\/j.apsb.2019.06.004"},{"key":"ref105\/cit105","doi-asserted-by":"publisher","DOI":"10.1002\/adma.201603095"},{"key":"ref106\/cit106","doi-asserted-by":"publisher","DOI":"10.1021\/acs.nanolett.0c02343"},{"key":"ref107\/cit107","doi-asserted-by":"publisher","DOI":"10.1021\/acsnano.2c02558"},{"key":"ref108\/cit108","doi-asserted-by":"publisher","DOI":"10.1002\/smtd.202301551"},{"key":"ref109\/cit109","doi-asserted-by":"publisher","DOI":"10.1126\/sciadv.adk0716"},{"key":"ref110\/cit110","doi-asserted-by":"publisher","DOI":"10.1021\/acs.nanolett.2c00185"},{"key":"ref111\/cit111","doi-asserted-by":"publisher","DOI":"10.1002\/smll.202309054"},{"key":"ref112\/cit112","doi-asserted-by":"publisher","DOI":"10.1002\/advs.202306230"},{"key":"ref113\/cit113","doi-asserted-by":"publisher","DOI":"10.1002\/anie.202312603"},{"key":"ref114\/cit114","doi-asserted-by":"publisher","DOI":"10.1021\/acsnano.2c12217"},{"issue":"1","key":"ref115\/cit115","first-page":"83","volume":"5","author":"Vasey P. A.","year":"1999","journal-title":"Clin. Cancer Res."},{"key":"ref116\/cit116","doi-asserted-by":"publisher","DOI":"10.1021\/acsnano.3c11958"},{"key":"ref117\/cit117","doi-asserted-by":"publisher","DOI":"10.1016\/j.nano.2022.102581"},{"key":"ref118\/cit118","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.4c00826"},{"key":"ref119\/cit119","doi-asserted-by":"publisher","DOI":"10.1186\/s12967-024-05301-9"},{"key":"ref120\/cit120","doi-asserted-by":"publisher","DOI":"10.1007\/s11426-018-9397-5"},{"key":"ref121\/cit121","doi-asserted-by":"publisher","DOI":"10.1517\/17425247.2016.1140147"},{"key":"ref122\/cit122","doi-asserted-by":"publisher","DOI":"10.1002\/adma.202002629"},{"key":"ref123\/cit123","doi-asserted-by":"publisher","DOI":"10.1007\/BF00928361"},{"key":"ref124\/cit124","doi-asserted-by":"publisher","DOI":"10.1016\/j.actbio.2020.12.057"},{"key":"ref125\/cit125","doi-asserted-by":"publisher","DOI":"10.1002\/adma.202310189"},{"key":"ref126\/cit126","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-024-48606-5"},{"key":"ref127\/cit127","doi-asserted-by":"publisher","DOI":"10.1186\/s11671-021-03628-6"},{"key":"ref128\/cit128","doi-asserted-by":"publisher","DOI":"10.1002\/adfm.202100386"},{"key":"ref129\/cit129","doi-asserted-by":"publisher","DOI":"10.1002\/adma.201800316"},{"key":"ref130\/cit130","doi-asserted-by":"publisher","DOI":"10.1021\/acsabm.3c01219"},{"key":"ref131\/cit131","doi-asserted-by":"publisher","DOI":"10.1039\/C7PY00914C"},{"key":"ref132\/cit132","doi-asserted-by":"publisher","DOI":"10.1039\/C8TB00651B"},{"key":"ref133\/cit133","doi-asserted-by":"publisher","DOI":"10.1039\/C4NR03302G"},{"key":"ref134\/cit134","doi-asserted-by":"publisher","DOI":"10.1021\/acs.macromol.6b01760"},{"key":"ref135\/cit135","doi-asserted-by":"publisher","DOI":"10.1021\/acsabm.9b00146"},{"key":"ref136\/cit136","doi-asserted-by":"publisher","DOI":"10.1021\/acsami.0c20152"},{"key":"ref137\/cit137","doi-asserted-by":"publisher","DOI":"10.1021\/acs.macromol.7b02637"},{"key":"ref138\/cit138","doi-asserted-by":"publisher","DOI":"10.1002\/anie.201711354"},{"key":"ref139\/cit139","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.6b08313"},{"key":"ref140\/cit140","doi-asserted-by":"publisher","DOI":"10.1002\/marc.201400171"},{"key":"ref141\/cit141","doi-asserted-by":"publisher","DOI":"10.1021\/acsami.1c16962"},{"key":"ref142\/cit142","doi-asserted-by":"publisher","DOI":"10.1038\/s41571-020-0410-2"},{"key":"ref143\/cit143","doi-asserted-by":"publisher","DOI":"10.3389\/fchem.2021.686303"},{"key":"ref144\/cit144","doi-asserted-by":"publisher","DOI":"10.1016\/j.jocn.2005.01.006"},{"key":"ref145\/cit145","doi-asserted-by":"publisher","DOI":"10.3171\/jns.1987.67.4.0500"},{"key":"ref146\/cit146","doi-asserted-by":"publisher","DOI":"10.1002\/lsm.20507"},{"key":"ref147\/cit147","doi-asserted-by":"publisher","DOI":"10.1007\/s11060-019-03103-4"},{"key":"ref148\/cit148","doi-asserted-by":"publisher","DOI":"10.1016\/j.cej.2023.147703"},{"key":"ref149\/cit149","doi-asserted-by":"publisher","DOI":"10.1007\/s40820-020-0378-6"},{"key":"ref150\/cit150","doi-asserted-by":"publisher","DOI":"10.1016\/j.cej.2023.144410"},{"key":"ref151\/cit151","doi-asserted-by":"publisher","DOI":"10.1016\/j.actbio.2022.07.045"},{"key":"ref152\/cit152","doi-asserted-by":"publisher","DOI":"10.1002\/smll.202300203"},{"key":"ref153\/cit153","doi-asserted-by":"publisher","DOI":"10.1021\/acsnano.3c09499"},{"key":"ref154\/cit154","doi-asserted-by":"publisher","DOI":"10.1021\/acsanm.2c00368"},{"key":"ref155\/cit155","doi-asserted-by":"publisher","DOI":"10.1021\/acsmaterialslett.1c00329"},{"key":"ref156\/cit156","doi-asserted-by":"publisher","DOI":"10.1002\/adma.202106082"},{"key":"ref157\/cit157","doi-asserted-by":"publisher","DOI":"10.1021\/acsnano.3c03724"},{"key":"ref158\/cit158","doi-asserted-by":"publisher","DOI":"10.1016\/j.apsb.2022.05.016"},{"key":"ref159\/cit159","doi-asserted-by":"publisher","DOI":"10.1016\/j.jconrel.2016.11.007"},{"key":"ref160\/cit160","doi-asserted-by":"publisher","DOI":"10.7150\/thno.38069"},{"key":"ref161\/cit161","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijpharm.2024.123847"},{"key":"ref162\/cit162","doi-asserted-by":"publisher","DOI":"10.1021\/acs.biomac.9b01026"},{"key":"ref163\/cit163","doi-asserted-by":"publisher","DOI":"10.1016\/j.eurpolymj.2024.112795"},{"key":"ref164\/cit164","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcis.2018.08.069"},{"key":"ref165\/cit165","doi-asserted-by":"publisher","DOI":"10.1021\/acs.biomac.3c01070"},{"key":"ref166\/cit166","doi-asserted-by":"publisher","DOI":"10.1007\/s10924-023-02842-w"},{"key":"ref167\/cit167","doi-asserted-by":"publisher","DOI":"10.1021\/acsnano.2c10094"},{"key":"ref168\/cit168","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2017.03.049"},{"key":"ref169\/cit169","doi-asserted-by":"publisher","DOI":"10.1016\/j.jconrel.2022.07.011"},{"key":"ref170\/cit170","doi-asserted-by":"publisher","DOI":"10.1158\/1078-0432.CCR-18-3850"},{"key":"ref171\/cit171","doi-asserted-by":"publisher","DOI":"10.3390\/gels9050418"},{"key":"ref172\/cit172","doi-asserted-by":"publisher","DOI":"10.1039\/C7NR05216B"},{"key":"ref173\/cit173","doi-asserted-by":"publisher","DOI":"10.1016\/j.jconrel.2023.01.070"},{"key":"ref174\/cit174","doi-asserted-by":"publisher","DOI":"10.1021\/acsami.3c03902"},{"key":"ref175\/cit175","doi-asserted-by":"publisher","DOI":"10.1039\/C9NR03931G"},{"key":"ref176\/cit176","doi-asserted-by":"publisher","DOI":"10.1016\/j.cej.2019.05.055"},{"key":"ref177\/cit177","doi-asserted-by":"publisher","DOI":"10.1088\/1361-6528\/ab0ce6"},{"key":"ref178\/cit178","doi-asserted-by":"publisher","DOI":"10.1158\/1078-0432.CCR-16-2433"},{"key":"ref179\/cit179","doi-asserted-by":"publisher","DOI":"10.1016\/j.xphs.2020.05.006"},{"key":"ref180\/cit180","doi-asserted-by":"publisher","DOI":"10.1002\/EXP.20210023"},{"key":"ref181\/cit181","doi-asserted-by":"publisher","DOI":"10.1021\/acsami.0c22489"},{"key":"ref182\/cit182","doi-asserted-by":"publisher","DOI":"10.1021\/acsami.1c04990"},{"key":"ref183\/cit183","doi-asserted-by":"publisher","DOI":"10.1002\/advs.202004381"},{"key":"ref184\/cit184","doi-asserted-by":"publisher","DOI":"10.1016\/j.jconrel.2020.03.013"},{"key":"ref185\/cit185","doi-asserted-by":"publisher","DOI":"10.1021\/acsnano.5b04378"},{"key":"ref186\/cit186","doi-asserted-by":"publisher","DOI":"10.1021\/acs.bioconjchem.8b00626"},{"key":"ref187\/cit187","doi-asserted-by":"publisher","DOI":"10.1007\/s00262-016-1891-9"},{"key":"ref188\/cit188","doi-asserted-by":"publisher","DOI":"10.1016\/j.cej.2017.12.051"},{"key":"ref189\/cit189","doi-asserted-by":"publisher","DOI":"10.1016\/j.ultsonch.2020.105217"},{"key":"ref190\/cit190","doi-asserted-by":"publisher","DOI":"10.1021\/la9018794"},{"key":"ref191\/cit191","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-018-28140-3"},{"key":"ref192\/cit192","doi-asserted-by":"publisher","DOI":"10.1039\/D0PY00254B"},{"key":"ref193\/cit193","doi-asserted-by":"publisher","DOI":"10.1007\/s10118-020-2345-6"},{"key":"ref194\/cit194","doi-asserted-by":"publisher","DOI":"10.1016\/j.ultsonch.2015.11.023"},{"key":"ref195\/cit195","doi-asserted-by":"publisher","DOI":"10.1002\/advs.202400485"},{"key":"ref196\/cit196","doi-asserted-by":"publisher","DOI":"10.1039\/c4cc00103f"},{"key":"ref197\/cit197","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-018-36340-0"},{"key":"ref198\/cit198","doi-asserted-by":"publisher","DOI":"10.1038\/s44222-023-00138-1"},{"key":"ref199\/cit199","doi-asserted-by":"publisher","DOI":"10.1016\/j.jconrel.2017.03.017"},{"key":"ref200\/cit200","doi-asserted-by":"publisher","DOI":"10.1016\/j.jconrel.2022.03.035"},{"key":"ref201\/cit201","doi-asserted-by":"publisher","DOI":"10.1002\/btm2.10408"},{"key":"ref202\/cit202","doi-asserted-by":"publisher","DOI":"10.1021\/acsami.8b22468"},{"key":"ref203\/cit203","doi-asserted-by":"publisher","DOI":"10.1016\/j.nano.2018.01.021"},{"key":"ref204\/cit204","doi-asserted-by":"publisher","DOI":"10.1148\/radiol.2016152444"},{"key":"ref205\/cit205","doi-asserted-by":"publisher","DOI":"10.1021\/acsanm.3c05575"},{"key":"ref206\/cit206","doi-asserted-by":"publisher","DOI":"10.1021\/acsnano.2c08861"},{"key":"ref207\/cit207","doi-asserted-by":"publisher","DOI":"10.1016\/j.actbio.2021.04.005"},{"key":"ref208\/cit208","doi-asserted-by":"publisher","DOI":"10.1021\/acsami.7b10866"},{"key":"ref209\/cit209","doi-asserted-by":"publisher","DOI":"10.1002\/advs.202203894"},{"key":"ref210\/cit210","doi-asserted-by":"publisher","DOI":"10.1039\/D3BM00585B"},{"key":"ref211\/cit211","doi-asserted-by":"publisher","DOI":"10.1080\/10717544.2023.2219429"},{"key":"ref212\/cit212","doi-asserted-by":"publisher","DOI":"10.1021\/acs.chemrev.5b00589"},{"key":"ref213\/cit213","doi-asserted-by":"publisher","DOI":"10.1007\/s13369-024-08724-0"},{"key":"ref214\/cit214","doi-asserted-by":"publisher","DOI":"10.1002\/smll.202306940"},{"key":"ref215\/cit215","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijbiomac.2024.129401"},{"key":"ref216\/cit216","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-024-57565-2"},{"key":"ref217\/cit217","doi-asserted-by":"publisher","DOI":"10.1021\/acsbiomaterials.9b00856"},{"key":"ref218\/cit218","doi-asserted-by":"publisher","DOI":"10.1039\/C8BM01528G"},{"key":"ref219\/cit219","doi-asserted-by":"publisher","DOI":"10.1039\/D3NJ00534H"},{"key":"ref220\/cit220","doi-asserted-by":"publisher","DOI":"10.1016\/j.jconrel.2023.01.072"},{"key":"ref221\/cit221","doi-asserted-by":"publisher","DOI":"10.1016\/j.jmmm.2021.167970"},{"key":"ref222\/cit222","doi-asserted-by":"publisher","DOI":"10.1016\/j.colsurfa.2021.126648"},{"key":"ref223\/cit223","doi-asserted-by":"publisher","DOI":"10.1007\/s11060-010-0389-0"},{"key":"ref224\/cit224","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1003388107"},{"key":"ref225\/cit225","doi-asserted-by":"publisher","DOI":"10.3390\/cancers13092283"},{"key":"ref226\/cit226","doi-asserted-by":"publisher","DOI":"10.1007\/s11864-015-0353-5"},{"key":"ref227\/cit227","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-019-43621-9"},{"key":"ref228\/cit228","doi-asserted-by":"publisher","DOI":"10.21037\/cco.2017.06.29"},{"key":"ref229\/cit229","doi-asserted-by":"publisher","DOI":"10.1093\/neuonc\/noz175.336"},{"key":"ref230\/cit230","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2017.18718"},{"key":"ref231\/cit231","doi-asserted-by":"publisher","DOI":"10.1016\/j.jddst.2023.104879"},{"key":"ref232\/cit232","doi-asserted-by":"publisher","DOI":"10.1016\/j.colsurfa.2022.128628"},{"key":"ref233\/cit233","doi-asserted-by":"publisher","DOI":"10.1007\/s13311-016-0431-9"},{"key":"ref234\/cit234","doi-asserted-by":"publisher","DOI":"10.14338\/IJPT-18-00023.1"},{"key":"ref235\/cit235","doi-asserted-by":"publisher","DOI":"10.1016\/S0168-3659(01)00335-2"},{"key":"ref236\/cit236","doi-asserted-by":"publisher","DOI":"10.1080\/028418600430789"},{"key":"ref237\/cit237","doi-asserted-by":"publisher","DOI":"10.1002\/adma.201806381"},{"key":"ref238\/cit238","doi-asserted-by":"publisher","DOI":"10.1021\/acsami.0c11627"},{"key":"ref239\/cit239","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-018-05118-3"},{"key":"ref240\/cit240","doi-asserted-by":"publisher","DOI":"10.1002\/aoc.7468"},{"key":"ref241\/cit241","doi-asserted-by":"publisher","DOI":"10.2147\/IJN.S164967"},{"key":"ref242\/cit242","doi-asserted-by":"publisher","DOI":"10.1021\/nl504044p"},{"key":"ref243\/cit243","doi-asserted-by":"publisher","DOI":"10.1021\/acs.nanolett.4c00223"},{"key":"ref244\/cit244","doi-asserted-by":"publisher","DOI":"10.1002\/adma.201903443"},{"key":"ref245\/cit245","doi-asserted-by":"publisher","DOI":"10.1021\/acsnano.3c00269"},{"key":"ref246\/cit246","doi-asserted-by":"publisher","DOI":"10.1002\/anie.201802351"},{"key":"ref247\/cit247","doi-asserted-by":"publisher","DOI":"10.1021\/acsbiomaterials.1c00385"},{"key":"ref248\/cit248","doi-asserted-by":"publisher","DOI":"10.1080\/09553002.2018.1495855"},{"key":"ref249\/cit249","doi-asserted-by":"publisher","DOI":"10.1007\/s12195-021-00675-y"},{"key":"ref250\/cit250","doi-asserted-by":"publisher","DOI":"10.1021\/acsnano.8b08177"},{"key":"ref251\/cit251","doi-asserted-by":"publisher","DOI":"10.1021\/acsami.2c12348"},{"key":"ref252\/cit252","doi-asserted-by":"publisher","DOI":"10.1021\/jacsau.3c00339"},{"key":"ref253\/cit253","doi-asserted-by":"publisher","DOI":"10.1016\/j.addr.2021.01.012"},{"key":"ref254\/cit254","doi-asserted-by":"publisher","DOI":"10.1016\/j.jconrel.2023.05.035"},{"key":"ref255\/cit255","doi-asserted-by":"publisher","DOI":"10.1039\/C5TB00468C"},{"key":"ref256\/cit256","doi-asserted-by":"publisher","DOI":"10.1021\/acsnano.3c00940"},{"key":"ref257\/cit257","doi-asserted-by":"publisher","DOI":"10.1016\/j.reactfunctpolym.2020.104532"},{"key":"ref258\/cit258","doi-asserted-by":"publisher","DOI":"10.1134\/S1560090419030047"},{"key":"ref259\/cit259","doi-asserted-by":"publisher","DOI":"10.1039\/D1CS00427A"},{"key":"ref260\/cit260","doi-asserted-by":"publisher","DOI":"10.1002\/adma.202311500"},{"key":"ref261\/cit261","doi-asserted-by":"publisher","DOI":"10.1021\/acsnano.4c01253"},{"key":"ref262\/cit262","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopha.2021.112144"},{"key":"ref263\/cit263","doi-asserted-by":"publisher","DOI":"10.1021\/acs.biomac.3c00138"},{"key":"ref264\/cit264","doi-asserted-by":"publisher","DOI":"10.1021\/acsami.9b14849"},{"key":"ref265\/cit265","doi-asserted-by":"publisher","DOI":"10.1002\/smtd.202201327"},{"key":"ref266\/cit266","doi-asserted-by":"publisher","DOI":"10.1016\/j.jconrel.2022.10.037"},{"key":"ref267\/cit267","doi-asserted-by":"publisher","DOI":"10.1016\/j.nantod.2022.101530"},{"key":"ref268\/cit268","doi-asserted-by":"publisher","DOI":"10.1002\/adma.201601902"},{"key":"ref269\/cit269","doi-asserted-by":"publisher","DOI":"10.2147\/IJN.S436160"},{"key":"ref270\/cit270","doi-asserted-by":"publisher","DOI":"10.1021\/acsami.3c18348"},{"key":"ref271\/cit271","doi-asserted-by":"publisher","DOI":"10.1021\/acs.biomac.0c01270"},{"key":"ref272\/cit272","doi-asserted-by":"publisher","DOI":"10.1002\/smll.201601997"}],"container-title":["Biomacromolecules"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acs.biomac.4c00722","content-type":"application\/pdf","content-version":"vor","intended-application":"unspecified"},{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acs.biomac.4c00722","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,10,14]],"date-time":"2024-10-14T04:11:31Z","timestamp":1728879091000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/acs.biomac.4c00722"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,9,11]]},"references-count":272,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2024,10,14]]}},"alternative-id":["10.1021\/acs.biomac.4c00722"],"URL":"https:\/\/doi.org\/10.1021\/acs.biomac.4c00722","relation":{},"ISSN":["1525-7797","1526-4602"],"issn-type":[{"value":"1525-7797","type":"print"},{"value":"1526-4602","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,9,11]]}}}