{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,30]],"date-time":"2026-10-30T00:49:36Z","timestamp":1793321376238,"version":"4.5.0"},"reference-count":62,"publisher":"American Chemical Society (ACS)","issue":"8","license":[{"start":{"date-parts":[[2025,7,7]],"date-time":"2025-07-07T00:00:00Z","timestamp":1751846400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100001309","name":"Research Corporation for Science Advancement","doi-asserted-by":"publisher","award":["27368"],"award-info":[{"award-number":["27368"]}],"id":[{"id":"10.13039\/100001309","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001659","name":"Deutsche Forschungsgemeinschaft","doi-asserted-by":"publisher","award":["HA5950\/5-2"],"award-info":[{"award-number":["HA5950\/5-2"]}],"id":[{"id":"10.13039\/501100001659","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001659","name":"Deutsche Forschungsgemeinschaft","doi-asserted-by":"publisher","award":["SCHE1552\/3-2"],"award-info":[{"award-number":["SCHE1552\/3-2"]}],"id":[{"id":"10.13039\/501100001659","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000089","name":"Office of International Science and Engineering","doi-asserted-by":"publisher","award":["1854028"],"award-info":[{"award-number":["1854028"]}],"id":[{"id":"10.13039\/100000089","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Biomacromolecules"],"published-print":{"date-parts":[[2025,8,11]]},"DOI":"10.1021\/acs.biomac.5c00576","type":"journal-article","created":{"date-parts":[[2025,7,7]],"date-time":"2025-07-07T00:33:41Z","timestamp":1751848421000},"page":"5169-5181","source":"Crossref","is-referenced-by-count":8,"title":["Controlling the Sulfation Density of Glycosaminoglycan Glycopolymer Mimetics Enables High Antiviral Activity against SARS-CoV-2 and Reduces Anticoagulant Activity"],"prefix":"10.1021","volume":"26","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7709-5886","authenticated-orcid":true,"given":"Miriam","family":"Hoffmann","sequence":"first","affiliation":[{"name":"Department of Organic and Macromolecular Chemistry, Heinrich-Heine-University D\u00fcsseldorf, Universit\u00e4tsstra\u00dfe 1, D\u00fcsseldorf 40225, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lorand","family":"Bonda","sequence":"additional","affiliation":[{"name":"Department of Organic and Macromolecular Chemistry, Heinrich-Heine-University D\u00fcsseldorf, Universit\u00e4tsstra\u00dfe 1, D\u00fcsseldorf 40225, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ines","family":"Fels","sequence":"additional","affiliation":[{"name":"Institute of Cellular Virology, ZMBE and Cells in Motion Interfaculty Centre CiMIC","place":["M\u00fcnster, Germany"]},{"name":"University of M\u00fcnster","place":["M\u00fcnster, Germany"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Darisuran","family":"Anhlan","sequence":"additional","affiliation":[{"name":"Institute of Molecular Virology, ZMBE","place":["M\u00fcnster, Germany"]},{"name":"University of M\u00fcnster","place":["M\u00fcnster, Germany"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eike","family":"Hrincius","sequence":"additional","affiliation":[{"name":"Institute of Molecular Virology, ZMBE","place":["M\u00fcnster, Germany"]},{"name":"University of M\u00fcnster","place":["M\u00fcnster, Germany"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Derik","family":"Hermsen","sequence":"additional","affiliation":[{"name":"Central Institute of Laboratory Medicine, Medical Faculty, University Hospital D\u00fcsseldorf","place":["D\u00fcsseldorf, Germany"]},{"name":"Heinrich-Heine-University","place":["D\u00fcsseldorf, Germany"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stephan","family":"Ludwig","sequence":"additional","affiliation":[{"name":"Institute of Molecular Virology, ZMBE","place":["M\u00fcnster, Germany"]},{"name":"University of M\u00fcnster","place":["M\u00fcnster, Germany"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mario","family":"Schelhaas","sequence":"additional","affiliation":[{"name":"Institute of Cellular Virology, ZMBE and Cells in Motion Interfaculty Centre CiMIC","place":["M\u00fcnster, Germany"]},{"name":"University of M\u00fcnster","place":["M\u00fcnster, Germany"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2508-4090","authenticated-orcid":true,"given":"Nicole L.","family":"Snyder","sequence":"additional","affiliation":[{"name":"Department of Chemistry","place":["Davidson, United States"]},{"name":"Davidson College","place":["Davidson, United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0115-6405","authenticated-orcid":true,"given":"Laura","family":"Hartmann","sequence":"additional","affiliation":[{"name":"Department of Organic and Macromolecular Chemistry, Heinrich-Heine-University D\u00fcsseldorf, Universit\u00e4tsstra\u00dfe 1, D\u00fcsseldorf 40225, Germany"},{"name":"Institute for Macromolecular Chemistry, University of Freiburg, Stefan-Meier-Street 31, Freiburg i.Br. 79104, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2025,7,7]]},"reference":[{"key":"ref1\/cit1","doi-asserted-by":"publisher","DOI":"10.1152\/ajpcell.00453.2022"},{"key":"ref2\/cit2","doi-asserted-by":"publisher","DOI":"10.1002\/advs.202201853"},{"key":"ref3\/cit3","doi-asserted-by":"publisher","DOI":"10.15252\/embj.2020106765"},{"key":"ref4\/cit4","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2020.09.033"},{"key":"ref5\/cit5","doi-asserted-by":"publisher","DOI":"10.1021\/acsmedchemlett.1c00343"},{"key":"ref6\/cit6","doi-asserted-by":"publisher","DOI":"10.1021\/acscentsci.1c00010"},{"key":"ref7\/cit7","doi-asserted-by":"publisher","DOI":"10.1016\/j.sbi.2022.102439"},{"key":"ref8\/cit8","doi-asserted-by":"publisher","DOI":"10.1111\/j.1747-0285.2008.00741.x"},{"key":"ref9\/cit9","doi-asserted-by":"publisher","DOI":"10.1369\/0022155412464972"},{"key":"ref10\/cit10","doi-asserted-by":"publisher","DOI":"10.3390\/ijms22126574"},{"key":"ref11\/cit11","doi-asserted-by":"publisher","DOI":"10.3390\/v14010035"},{"key":"ref12\/cit12","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa2015432"},{"key":"ref13\/cit13","doi-asserted-by":"publisher","DOI":"10.1111\/jth.14860"},{"key":"ref14\/cit14","doi-asserted-by":"publisher","DOI":"10.3390\/ph10040078"},{"key":"ref15\/cit15","doi-asserted-by":"publisher","DOI":"10.1038\/nbt1407"},{"key":"ref16\/cit16","doi-asserted-by":"publisher","DOI":"10.1039\/b819896a"},{"key":"ref17\/cit17","doi-asserted-by":"publisher","DOI":"10.1016\/j.sbi.2017.12.011"},{"key":"ref18\/cit18","doi-asserted-by":"publisher","DOI":"10.1038\/pj.2015.110"},{"key":"ref19\/cit19","doi-asserted-by":"publisher","DOI":"10.1021\/acs.biomac.6b01147"},{"key":"ref20\/cit20","doi-asserted-by":"publisher","DOI":"10.1039\/c8py01338a"},{"key":"ref21\/cit21","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.7b01923"},{"key":"ref22\/cit22","doi-asserted-by":"publisher","DOI":"10.1002\/tcr.202100173"},{"key":"ref23\/cit23","doi-asserted-by":"publisher","DOI":"10.1021\/acscentsci.1c01293"},{"key":"ref24\/cit24","doi-asserted-by":"publisher","DOI":"10.1016\/j.synbio.2022.10.002"},{"key":"ref25\/cit25","doi-asserted-by":"publisher","DOI":"10.1021\/jacsau.3c00042"},{"key":"ref26\/cit26","doi-asserted-by":"publisher","DOI":"10.3390\/biom14091052"},{"key":"ref27\/cit27","doi-asserted-by":"publisher","DOI":"10.1007\/s10719-024-10150-1"},{"key":"ref28\/cit28","doi-asserted-by":"publisher","DOI":"10.1021\/acs.macromol.2c00675"},{"key":"ref29\/cit29","doi-asserted-by":"publisher","DOI":"10.1039\/D2CS00912A"},{"key":"ref30\/cit30","doi-asserted-by":"publisher","DOI":"10.1002\/anie.202102717"},{"key":"ref31\/cit31","doi-asserted-by":"publisher","DOI":"10.1021\/acsmedchemlett.3c00319"},{"key":"ref32\/cit32","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.9b13484"},{"key":"ref33\/cit33","doi-asserted-by":"publisher","DOI":"10.1016\/j.carres.2014.09.009"},{"key":"ref34\/cit34","doi-asserted-by":"publisher","DOI":"10.3390\/vaccines8030386"},{"key":"ref35\/cit35","doi-asserted-by":"publisher","DOI":"10.3390\/ph15050530"},{"key":"ref36\/cit36","doi-asserted-by":"publisher","DOI":"10.1371\/journal.ppat.1009580"},{"key":"ref37\/cit37","doi-asserted-by":"publisher","DOI":"10.1093\/glycob\/cwn092"},{"key":"ref38\/cit38","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopha.2024.117700"},{"key":"ref39\/cit39","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvs.2011.10.082"},{"key":"ref40\/cit40","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.273.39.24979"},{"key":"ref41\/cit41","doi-asserted-by":"publisher","DOI":"10.1369\/0022155412464972"},{"key":"ref42\/cit42","doi-asserted-by":"publisher","DOI":"10.1021\/ja302193u"},{"key":"ref43\/cit43","doi-asserted-by":"publisher","DOI":"10.1002\/pola.26646"},{"key":"ref44\/cit44","doi-asserted-by":"publisher","DOI":"10.1021\/acs.biomac.6b01657"},{"key":"ref45\/cit45","doi-asserted-by":"publisher","DOI":"10.1039\/C7CC07107H"},{"key":"ref46\/cit46","doi-asserted-by":"publisher","DOI":"10.1002\/chem.201704179"},{"key":"ref47\/cit47","doi-asserted-by":"publisher","DOI":"10.1039\/C9FD00028C"},{"key":"ref48\/cit48","doi-asserted-by":"publisher","DOI":"10.1529\/biophysj.105.067918"},{"key":"ref49\/cit49","doi-asserted-by":"publisher","DOI":"10.1016\/j.csbj.2022.07.013"},{"key":"ref50\/cit50","doi-asserted-by":"publisher","DOI":"10.3390\/ijms222413202"},{"key":"ref51\/cit51","doi-asserted-by":"publisher","DOI":"10.1124\/pr.115.011247"},{"key":"ref52\/cit52","doi-asserted-by":"publisher","DOI":"10.1039\/b819896a"},{"key":"ref53\/cit53","doi-asserted-by":"publisher","DOI":"10.1016\/S1367-5931(00)00145-9"},{"key":"ref54\/cit54","doi-asserted-by":"publisher","DOI":"10.1016\/j.biochi.2010.05.011"},{"key":"ref55\/cit55","doi-asserted-by":"publisher","DOI":"10.1038\/sj.emboj.7601089"},{"key":"ref56\/cit56","doi-asserted-by":"publisher","DOI":"10.1038\/nsmb811"},{"key":"ref57\/cit57","first-page":"111","volume-title":"Methods in Molecular Biology","volume":"992","author":"Ignjatovic V.","year":"2013"},{"key":"ref58\/cit58","first-page":"131","volume-title":"Methods in Molecular Biology","volume":"992","author":"Ignjatovic V.","year":"2013"},{"key":"ref59\/cit59","doi-asserted-by":"publisher","DOI":"10.1021\/acs.biomac.6b01147"},{"key":"ref60\/cit60","doi-asserted-by":"publisher","DOI":"10.1021\/acs.biomac.9b01688"},{"key":"ref61\/cit61","doi-asserted-by":"publisher","DOI":"10.1002\/mabi.202000110"},{"key":"ref62\/cit62","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jmedchem.3c00132"}],"container-title":["Biomacromolecules"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acs.biomac.5c00576","content-type":"application\/pdf","content-version":"vor","intended-application":"unspecified"},{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acs.biomac.5c00576","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,11]],"date-time":"2025-08-11T08:12:56Z","timestamp":1754899976000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/acs.biomac.5c00576"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,7,7]]},"references-count":62,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2025,8,11]]}},"alternative-id":["10.1021\/acs.biomac.5c00576"],"URL":"https:\/\/doi.org\/10.1021\/acs.biomac.5c00576","relation":{},"ISSN":["1525-7797","1526-4602"],"issn-type":[{"value":"1525-7797","type":"print"},{"value":"1526-4602","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,7,7]]}}}