{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,7]],"date-time":"2026-11-07T01:06:04Z","timestamp":1794013564768,"version":"4.8.0"},"reference-count":49,"publisher":"American Chemical Society (ACS)","issue":"11","license":[{"start":{"date-parts":[[2025,10,20]],"date-time":"2025-10-20T00:00:00Z","timestamp":1760918400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2025,10,20]],"date-time":"2025-10-20T00:00:00Z","timestamp":1760918400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2025,10,20]],"date-time":"2025-10-20T00:00:00Z","timestamp":1760918400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-045"}],"funder":[{"DOI":"10.13039\/501100007194","name":"Wenzhou Municipal Science and Technology Bureau","doi-asserted-by":"publisher","award":["2023Y0847"],"award-info":[{"award-number":["2023Y0847"]}],"id":[{"id":"10.13039\/501100007194","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100011332","name":"University of Chinese Academy of Sciences","doi-asserted-by":"publisher","award":["WIUCASQD2021046"],"award-info":[{"award-number":["WIUCASQD2021046"]}],"id":[{"id":"10.13039\/501100011332","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004731","name":"Natural Science Foundation of Zhejiang Province","doi-asserted-by":"publisher","award":["LQ24H120002"],"award-info":[{"award-number":["LQ24H120002"]}],"id":[{"id":"10.13039\/501100004731","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Biomacromolecules"],"published-print":{"date-parts":[[2025,11,10]]},"DOI":"10.1021\/acs.biomac.5c01176","type":"journal-article","created":{"date-parts":[[2025,10,21]],"date-time":"2025-10-21T02:21:40Z","timestamp":1761013300000},"page":"7656-7669","source":"Crossref","is-referenced-by-count":9,"title":["Azo-Linked 5-ASA Hydrogel Microparticles with Enzyme Shielding for Sustained Drug Release in Ulcerative Colitis Therapy"],"prefix":"10.1021","volume":"26","author":[{"given":"Yuhao","family":"Jiang","sequence":"first","affiliation":[{"name":"College of Life and Environmental Science","place":["Wenzhou, China"]},{"name":"Wenzhou University","place":["Wenzhou, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuan","family":"Wang","sequence":"additional","affiliation":[{"name":"School of Pharmaceutical Sciences","place":["Hangzhou, China"]},{"name":"Zhejiang Chinese Medical University","place":["Hangzhou, China"]},{"name":"Wenzhou Institute","place":["Wenzhou, China"]},{"name":"University of Chinese Academy Science","place":["Wenzhou, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yansong","family":"Zhang","sequence":"additional","affiliation":[{"name":"School of Pharmaceutical Sciences","place":["Hangzhou, China"]},{"name":"Zhejiang Chinese Medical University","place":["Hangzhou, China"]},{"name":"Wenzhou Institute","place":["Wenzhou, China"]},{"name":"University of Chinese Academy Science","place":["Wenzhou, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xingjie","family":"Zan","sequence":"additional","affiliation":[{"name":"Wenzhou Institute","place":["Wenzhou, China"]},{"name":"University of Chinese Academy Science","place":["Wenzhou, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Haibin","family":"Tong","sequence":"additional","affiliation":[{"name":"College of Life and Environmental Science","place":["Wenzhou, China"]},{"name":"Wenzhou University","place":["Wenzhou, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1046-0847","authenticated-orcid":true,"given":"Sicheng","family":"Tang","sequence":"additional","affiliation":[{"name":"School of Pharmaceutical Sciences","place":["Hangzhou, China"]},{"name":"Zhejiang Chinese Medical University","place":["Hangzhou, China"]},{"name":"Wenzhou Institute","place":["Wenzhou, China"]},{"name":"University of Chinese Academy Science","place":["Wenzhou, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2025,10,20]]},"reference":[{"key":"ref1\/cit1","doi-asserted-by":"publisher","DOI":"10.3390\/cancers13092025"},{"key":"ref2\/cit2","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2022.01.023"},{"key":"ref3\/cit3","doi-asserted-by":"publisher","DOI":"10.3390\/biomedicines11030825"},{"key":"ref4\/cit4","doi-asserted-by":"publisher","DOI":"10.1002\/ibd.22939"},{"key":"ref5\/cit5","doi-asserted-by":"publisher","DOI":"10.1080\/14712598.2019.1666101"},{"key":"ref6\/cit6","doi-asserted-by":"publisher","DOI":"10.1007\/BF01308084"},{"key":"ref7\/cit7","doi-asserted-by":"publisher","DOI":"10.1016\/S0090-9556(24)15210-5"},{"key":"ref8\/cit8","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2036.2008.03751.x"},{"key":"ref9\/cit9","doi-asserted-by":"publisher","DOI":"10.1016\/j.carbpol.2022.119351"},{"key":"ref10\/cit10","doi-asserted-by":"publisher","DOI":"10.2174\/0929867329666220707102912"},{"key":"ref11\/cit11","doi-asserted-by":"publisher","DOI":"10.1016\/S0168-3659(02)00084-6"},{"key":"ref12\/cit12","doi-asserted-by":"publisher","DOI":"10.3892\/br.2021.1472"},{"key":"ref13\/cit13","doi-asserted-by":"publisher","DOI":"10.1016\/j.jddst.2022.103578"},{"key":"ref14\/cit14","doi-asserted-by":"publisher","DOI":"10.1016\/j.msec.2020.111582"},{"key":"ref15\/cit15","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejps.2021.106072"},{"key":"ref16\/cit16","doi-asserted-by":"publisher","DOI":"10.1016\/j.drudis.2023.103606"},{"issue":"5","key":"ref17\/cit17","first-page":"893","volume":"3","author":"Karagozian R.","year":"2007","journal-title":"Ther Clin Risk Manag"},{"key":"ref18\/cit18","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejpb.2022.12.013"},{"key":"ref19\/cit19","doi-asserted-by":"publisher","DOI":"10.1002\/cmdc.202100046"},{"key":"ref20\/cit20","doi-asserted-by":"publisher","DOI":"10.1002\/cbdv.202301169"},{"key":"ref21\/cit21","doi-asserted-by":"publisher","DOI":"10.1023\/A:1011033121528"},{"key":"ref22\/cit22","doi-asserted-by":"publisher","DOI":"10.1039\/D4NJ04860A"},{"key":"ref23\/cit23","doi-asserted-by":"publisher","DOI":"10.2174\/1871528112666131122103940"},{"key":"ref24\/cit24","doi-asserted-by":"publisher","DOI":"10.2165\/00003088-198510040-00001"},{"key":"ref25\/cit25","doi-asserted-by":"publisher","DOI":"10.1016\/j.talanta.2024.127277"},{"key":"ref26\/cit26","doi-asserted-by":"publisher","DOI":"10.1186\/s12951-024-02724-w"},{"key":"ref27\/cit27","doi-asserted-by":"publisher","DOI":"10.1016\/j.cej.2014.01.065"},{"key":"ref28\/cit28","doi-asserted-by":"publisher","DOI":"10.1021\/acsami.2c02614"},{"key":"ref29\/cit29","doi-asserted-by":"publisher","DOI":"10.1016\/j.jclepro.2018.06.259"},{"issue":"06","key":"ref30\/cit30","first-page":"1012","volume":"25","author":"Gao C.","year":"2013","journal-title":"Prog. Chem."},{"key":"ref31\/cit31","doi-asserted-by":"publisher","DOI":"10.1039\/D0RA04316H"},{"key":"ref32\/cit32","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijbiomac.2023.125472"},{"key":"ref33\/cit33","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijpharm.2023.123222"},{"key":"ref34\/cit34","doi-asserted-by":"publisher","DOI":"10.53388\/bmec2024009"},{"key":"ref35\/cit35","doi-asserted-by":"publisher","DOI":"10.1016\/j.jddst.2019.101495"},{"key":"ref36\/cit36","doi-asserted-by":"publisher","DOI":"10.1021\/acs.biomac.3c00146"},{"key":"ref37\/cit37","doi-asserted-by":"publisher","DOI":"10.3390\/pharmaceutics13070951"},{"key":"ref38\/cit38","doi-asserted-by":"publisher","DOI":"10.1002\/advs.202205422"},{"key":"ref39\/cit39","doi-asserted-by":"publisher","DOI":"10.1021\/acsnano.3c02646"},{"key":"ref40\/cit40","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-021-27463-6"},{"key":"ref41\/cit41","doi-asserted-by":"publisher","DOI":"10.1016\/j.bioorg.2019.03.013"},{"key":"ref42\/cit42","doi-asserted-by":"publisher","DOI":"10.1016\/j.molliq.2018.04.002"},{"issue":"2","key":"ref43\/cit43","first-page":"60","volume":"3","author":"Hasnain J.","year":"2011","journal-title":"ISRA Medical Journal"},{"key":"ref44\/cit44","doi-asserted-by":"publisher","DOI":"10.3390\/ph15101259"},{"key":"ref45\/cit45","doi-asserted-by":"publisher","DOI":"10.3389\/fphar.2021.618411"},{"key":"ref46\/cit46","doi-asserted-by":"publisher","DOI":"10.5056\/jnm.2012.18.1.64"},{"key":"ref47\/cit47","doi-asserted-by":"publisher","DOI":"10.1016\/j.compositesb.2022.109826"},{"key":"ref48\/cit48","doi-asserted-by":"publisher","DOI":"10.1021\/bk-2020-1350.ch001"},{"key":"ref49\/cit49","doi-asserted-by":"publisher","DOI":"10.1038\/srep43126"}],"container-title":["Biomacromolecules"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acs.biomac.5c01176","content-type":"application\/pdf","content-version":"vor","intended-application":"unspecified"},{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acs.biomac.5c01176","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,11,10]],"date-time":"2025-11-10T09:29:34Z","timestamp":1762766974000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/acs.biomac.5c01176"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,10,20]]},"references-count":49,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2025,11,10]]}},"alternative-id":["10.1021\/acs.biomac.5c01176"],"URL":"https:\/\/doi.org\/10.1021\/acs.biomac.5c01176","relation":{},"ISSN":["1525-7797","1526-4602"],"issn-type":[{"value":"1525-7797","type":"print"},{"value":"1526-4602","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,10,20]]}}}