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This study developed a bifunctional heparin\/zwitterionic polymer (CBMA) coating on dopamine-modified stents via surface-initiated atom transfer radical polymerization (SI-ATRP). The coating integrates CBMA\u2019s antifouling properties (98.5% reduction in BSA adsorption) with heparin\u2019s sustained anticoagulation (37% APTT prolongation, 17 s TT increase) and endothelialization promotion (194.97% endothelial cell activity after 5 days). Animal trials confirmed reduced TNF-\u03b1 expression (75% decrease), enhanced collagen deposition, neovascularization post-28 days, and preserved mechanical strength (diametral tensile strength &amp;gt;57 MPa) with 25% lower permeability. 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