{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T19:58:07Z","timestamp":1792699087538,"version":"4.5.0"},"reference-count":43,"publisher":"American Chemical Society (ACS)","issue":"1","license":[{"start":{"date-parts":[[2025,12,24]],"date-time":"2025-12-24T00:00:00Z","timestamp":1766534400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100031478","name":"NextGenerationEU","doi-asserted-by":"publisher","award":["CUP G53D23003300001"],"award-info":[{"award-number":["CUP G53D23003300001"]}],"id":[{"id":"10.13039\/100031478","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Biomacromolecules"],"published-print":{"date-parts":[[2026,1,12]]},"DOI":"10.1021\/acs.biomac.5c02110","type":"journal-article","created":{"date-parts":[[2025,12,24]],"date-time":"2025-12-24T20:22:11Z","timestamp":1766607731000},"page":"845-854","source":"Crossref","is-referenced-by-count":1,"title":["Encapsulated Control: Shaping Insulin Fibrillation through Polymer Confinement"],"prefix":"10.1021","volume":"27","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6775-2563","authenticated-orcid":true,"given":"Anastasiia","family":"Murmiliuk","sequence":"first","affiliation":[{"name":"Department of Medical Biotechnology and Translational Medicine","place":["Segrate, Italy"]},{"name":"Universit\u00e0 degli Studi di Milano","place":["Segrate, Italy"]},{"name":"J\u00fclich Centre for Neutron Science (JCNS) at Heinz Maier-Leibnitz Zentrum (MLZ)","place":["Garching, Germany"]},{"name":"Forschungszentrum J\u00fclich GmbH","place":["Garching, Germany"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4253-5076","authenticated-orcid":true,"given":"Sergey K.","family":"Filippov","sequence":"additional","affiliation":[{"name":"DWI \u2212 Leibniz Institute for Interactive Materials","place":["Aachen, Germany"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4038-7839","authenticated-orcid":true,"given":"Hiroki","family":"Iwase","sequence":"additional","affiliation":[{"name":"Neutron Science and Technology Center","place":["Tokai, Japan"]},{"name":"Comprehensive Research Organization for Science and Society (CROSS)","place":["Tokai, Japan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0001-9936-9056","authenticated-orcid":true,"given":"Kuno","family":"Schw\u00e4rzer","sequence":"additional","affiliation":[{"name":"J\u00fclich Centre for Neutron Science (JCNS-1)","place":["J\u00fclich, Germany"]},{"name":"Forschungszentrum J\u00fclich","place":["J\u00fclich, Germany"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9276-597X","authenticated-orcid":true,"given":"J\u00fcrgen","family":"Allgaier","sequence":"additional","affiliation":[{"name":"J\u00fclich Centre for Neutron Science (JCNS-1)","place":["J\u00fclich, Germany"]},{"name":"Forschungszentrum J\u00fclich","place":["J\u00fclich, Germany"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aurel","family":"Radulescu","sequence":"additional","affiliation":[{"name":"J\u00fclich Centre for Neutron Science (JCNS) at Heinz Maier-Leibnitz Zentrum (MLZ)","place":["Garching, Germany"]},{"name":"Forschungszentrum J\u00fclich GmbH","place":["Garching, Germany"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2025,12,24]]},"reference":[{"key":"ref1\/cit1","doi-asserted-by":"publisher","DOI":"10.1007\/s12551-019-00526-1"},{"key":"ref2\/cit2","doi-asserted-by":"publisher","DOI":"10.1016\/j.tim.2020.09.005"},{"key":"ref3\/cit3","doi-asserted-by":"publisher","DOI":"10.3390\/ijms22094349"},{"key":"ref4\/cit4","doi-asserted-by":"publisher","DOI":"10.1002\/cphc.200700222"},{"key":"ref5\/cit5","doi-asserted-by":"publisher","DOI":"10.1002\/marc.201400728"},{"key":"ref6\/cit6","doi-asserted-by":"publisher","DOI":"10.1039\/D3CP03103A"},{"key":"ref7\/cit7","doi-asserted-by":"publisher","DOI":"10.1186\/s12902-019-0385-0"},{"key":"ref8\/cit8","doi-asserted-by":"publisher","DOI":"10.1021\/bi0507940"},{"key":"ref9\/cit9","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pbio.0050134"},{"key":"ref10\/cit10","doi-asserted-by":"publisher","DOI":"10.1107\/S1399004715001674"},{"key":"ref11\/cit11","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcis.2024.03.156"},{"key":"ref12\/cit12","doi-asserted-by":"publisher","DOI":"10.3390\/polym12020309"},{"key":"ref13\/cit13","doi-asserted-by":"publisher","DOI":"10.1134\/S263482762260013X"},{"key":"ref14\/cit14","doi-asserted-by":"publisher","DOI":"10.1021\/acsmacrolett.7b00974"},{"key":"ref15\/cit15","doi-asserted-by":"publisher","DOI":"10.1021\/acs.bioconjchem.6b00659"},{"key":"ref16\/cit16","doi-asserted-by":"publisher","DOI":"10.1021\/acs.biomac.0c00133"},{"key":"ref17\/cit17","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijpharm.2015.06.013"},{"key":"ref18\/cit18","doi-asserted-by":"publisher","DOI":"10.1002\/jps.20520"},{"key":"ref19\/cit19","doi-asserted-by":"publisher","DOI":"10.1016\/S0378-5173(96)04700-X"},{"key":"ref20\/cit20","doi-asserted-by":"publisher","DOI":"10.1002\/adfm.201705475"},{"key":"ref21\/cit21","doi-asserted-by":"publisher","DOI":"10.7566\/JPSCP.8.036020"},{"key":"ref22\/cit22","doi-asserted-by":"publisher","DOI":"10.1007\/s11661-009-9950-x"},{"key":"ref23\/cit23","unstructured":"Kohlbrecher, J.\n                      SASfit: A Program for Tting Simple Structural Models to Small Angle Scattering Data\n                      ; SASfit, 2018."},{"key":"ref24\/cit24","doi-asserted-by":"publisher","DOI":"10.1021\/ma9512115"},{"key":"ref25\/cit25","doi-asserted-by":"publisher","DOI":"10.1107\/S0021889899012248"},{"key":"ref26\/cit26","unstructured":"Kohlbrecher, J.\n                      User Guide for the SASfit Software Package\n                      ; SASfit, 2014, 1\u2013420."},{"key":"ref27\/cit27","doi-asserted-by":"publisher","DOI":"10.1103\/PhysRevA.22.1733"},{"key":"ref28\/cit28","doi-asserted-by":"publisher","DOI":"10.1103\/PhysRevE.50.5047"},{"key":"ref29\/cit29","doi-asserted-by":"publisher","DOI":"10.1021\/la00044a029"},{"key":"ref30\/cit30","doi-asserted-by":"publisher","DOI":"10.1103\/PhysRevE.60.7143"},{"key":"ref31\/cit31","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gky497"},{"key":"ref32\/cit32","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1500851112"},{"key":"ref33\/cit33","doi-asserted-by":"publisher","DOI":"10.1021\/acsptsci.2c00174"},{"key":"ref34\/cit34","doi-asserted-by":"publisher","DOI":"10.1016\/S0006-3495(99)77012-8"},{"key":"ref35\/cit35","doi-asserted-by":"publisher","DOI":"10.1021\/acsmacrolett.8b00484"},{"key":"ref36\/cit36","doi-asserted-by":"publisher","DOI":"10.3390\/polym13020214"},{"key":"ref37\/cit37","doi-asserted-by":"publisher","DOI":"10.1039\/D0ME00147C"},{"key":"ref38\/cit38","doi-asserted-by":"publisher","DOI":"10.1021\/acs.macromol.2c01121"},{"key":"ref39\/cit39","unstructured":"30.4.1 Bigaussian\n                      ; OriginLab Corporation, Northampton, MA, USA. https:\/\/www.originlab.com\/doc\/Origin-Help\/Bigaussian-PAFunc (accessed 30 November 2025)."},{"key":"ref40\/cit40","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejpb.2019.08.007"},{"key":"ref41\/cit41","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcis.2021.01.044"},{"key":"ref42\/cit42","doi-asserted-by":"publisher","DOI":"10.1063\/1.1746740"},{"key":"ref43\/cit43","doi-asserted-by":"publisher","DOI":"10.1063\/1.1746738"}],"container-title":["Biomacromolecules"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acs.biomac.5c02110","content-type":"application\/pdf","content-version":"vor","intended-application":"unspecified"},{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acs.biomac.5c02110","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,1,16]],"date-time":"2026-01-16T13:24:13Z","timestamp":1768569853000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/acs.biomac.5c02110"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,12,24]]},"references-count":43,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2026,1,12]]}},"alternative-id":["10.1021\/acs.biomac.5c02110"],"URL":"https:\/\/doi.org\/10.1021\/acs.biomac.5c02110","relation":{},"ISSN":["1525-7797","1526-4602"],"issn-type":[{"value":"1525-7797","type":"print"},{"value":"1526-4602","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,12,24]]}}}