{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,4]],"date-time":"2026-11-04T05:38:20Z","timestamp":1793770700186,"version":"4.6.1"},"reference-count":59,"publisher":"American Chemical Society (ACS)","issue":"6","license":[{"start":{"date-parts":[[2026,5,14]],"date-time":"2026-05-14T00:00:00Z","timestamp":1778716800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,5,14]],"date-time":"2026-05-14T00:00:00Z","timestamp":1778716800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,5,14]],"date-time":"2026-05-14T00:00:00Z","timestamp":1778716800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-045"}],"funder":[{"DOI":"10.13039\/100023581","name":"National Science Foundation Graduate Research Fellowship Program","doi-asserted-by":"publisher","award":["2235036"],"award-info":[{"award-number":["2235036"]}],"id":[{"id":"10.13039\/100023581","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["P20GM103476"],"award-info":[{"award-number":["P20GM103476"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000001","name":"National Science Foundation","doi-asserted-by":"publisher","award":["2141666"],"award-info":[{"award-number":["2141666"]}],"id":[{"id":"10.13039\/100000001","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000001","name":"National Science Foundation","doi-asserted-by":"publisher","award":["2414442"],"award-info":[{"award-number":["2414442"]}],"id":[{"id":"10.13039\/100000001","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Biomacromolecules"],"published-print":{"date-parts":[[2026,6,8]]},"DOI":"10.1021\/acs.biomac.6c00138","type":"journal-article","created":{"date-parts":[[2026,5,14]],"date-time":"2026-05-14T06:02:17Z","timestamp":1778738537000},"page":"3675-3685","source":"Crossref","is-referenced-by-count":1,"title":["Tunable PEG-Azlactone Hydrogels Enable Programmable Multiphase Drug Delivery"],"prefix":"10.1021","volume":"27","author":[{"given":"Emily","family":"Rasmussen","sequence":"first","affiliation":[{"name":"Department of Biomedical Engineering","place":["University, United States"]},{"name":"University of Mississippi","place":["University, United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S. K. Arif","family":"Mohammad","sequence":"additional","affiliation":[{"name":"Department of Biomedical Engineering","place":["University, United States"]},{"name":"University of Mississippi","place":["University, United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kendall","family":"Kelly","sequence":"additional","affiliation":[{"name":"Department of Biomedical Engineering","place":["University, United States"]},{"name":"University of Mississippi","place":["University, United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ally Grace","family":"Bounds","sequence":"additional","affiliation":[{"name":"Department of Biomedical Engineering","place":["University, United States"]},{"name":"University of Mississippi","place":["University, United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kenneth","family":"Hulugalla","sequence":"additional","affiliation":[{"name":"Department of Biomedical Engineering","place":["University, United States"]},{"name":"University of Mississippi","place":["University, United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Penelope","family":"Jankoski","sequence":"additional","affiliation":[{"name":"School of Polymer Science and Engineering","place":["Hattiesburg, United States"]},{"name":"University of Southern Mississippi","place":["Hattiesburg, United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Evan","family":"Stacy","sequence":"additional","affiliation":[{"name":"School of Polymer Science and Engineering","place":["Hattiesburg, United States"]},{"name":"University of Southern Mississippi","place":["Hattiesburg, United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"William L.","family":"Jarrett","sequence":"additional","affiliation":[{"name":"School of Polymer Science and Engineering","place":["Hattiesburg, United States"]},{"name":"University of Southern Mississippi","place":["Hattiesburg, United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8042-0141","authenticated-orcid":true,"given":"Tristan","family":"Clemons","sequence":"additional","affiliation":[{"name":"School of Polymer Science and Engineering","place":["Hattiesburg, United States"]},{"name":"University of Southern Mississippi","place":["Hattiesburg, United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1733-443X","authenticated-orcid":true,"given":"Adam E.","family":"Smith","sequence":"additional","affiliation":[{"name":"Department of Biomedical Engineering","place":["University, United States"]},{"name":"University of Mississippi","place":["University, United States"]},{"name":"Department of Chemical Engineering","place":["University, United States"]},{"name":"University of Mississippi","place":["University, United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6005-1243","authenticated-orcid":true,"given":"Thomas A.","family":"Werfel","sequence":"additional","affiliation":[{"name":"Department of Biomedical Engineering","place":["University, United States"]},{"name":"University of Mississippi","place":["University, United States"]},{"name":"Department of Chemical Engineering","place":["University, United States"]},{"name":"University of Mississippi","place":["University, United States"]},{"name":"Department of BioMolecular Sciences","place":["University, United States"]},{"name":"University of Mississippi","place":["University, United States"]},{"name":"Cancer Center and Research Institute","place":["Jackson, United States"]},{"name":"University of Mississippi Medical Center","place":["Jackson, United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2026,5,14]]},"reference":[{"key":"ref1\/cit1","doi-asserted-by":"publisher","DOI":"10.1016\/j.nantod.2020.100914"},{"key":"ref2\/cit2","doi-asserted-by":"publisher","DOI":"10.1182\/blood.V26.5.642.642"},{"key":"ref3\/cit3","doi-asserted-by":"publisher","DOI":"10.1038\/nbt.2284"},{"key":"ref4\/cit4","doi-asserted-by":"publisher","DOI":"10.18632\/oncotarget.16723"},{"key":"ref5\/cit5","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199803263381301"},{"key":"ref6\/cit6","doi-asserted-by":"publisher","DOI":"10.3389\/fphar.2022.838277"},{"key":"ref7\/cit7","doi-asserted-by":"publisher","DOI":"10.1016\/j.addr.2015.10.022"},{"key":"ref8\/cit8","doi-asserted-by":"publisher","DOI":"10.1038\/nbt.1549"},{"key":"ref9\/cit9","doi-asserted-by":"publisher","DOI":"10.1016\/j.addr.2019.11.001"},{"key":"ref10\/cit10","doi-asserted-by":"publisher","DOI":"10.1016\/j.addr.2017.04.003"},{"key":"ref11\/cit11","doi-asserted-by":"publisher","DOI":"10.1016\/j.heliyon.2023.e17488"},{"key":"ref12\/cit12","doi-asserted-by":"publisher","DOI":"10.1016\/j.addr.2024.115326"},{"key":"ref13\/cit13","doi-asserted-by":"publisher","DOI":"10.2174\/187221107779814096"},{"key":"ref14\/cit14","doi-asserted-by":"publisher","DOI":"10.1038\/natrevmats.2016.71"},{"key":"ref15\/cit15","doi-asserted-by":"publisher","DOI":"10.3390\/gels9070523"},{"key":"ref16\/cit16","doi-asserted-by":"publisher","DOI":"10.1126\/sciadv.adc8738"},{"key":"ref17\/cit17","doi-asserted-by":"publisher","DOI":"10.1016\/j.eurpolymj.2014.11.024"},{"key":"ref18\/cit18","doi-asserted-by":"publisher","DOI":"10.1016\/j.addr.2012.09.010"},{"key":"ref19\/cit19","doi-asserted-by":"publisher","DOI":"10.3390\/pharmaceutics15102514"},{"key":"ref20\/cit20","doi-asserted-by":"publisher","DOI":"10.1002\/btm2.10158"},{"key":"ref21\/cit21","doi-asserted-by":"publisher","DOI":"10.3390\/polym17212862"},{"key":"ref22\/cit22","doi-asserted-by":"publisher","DOI":"10.1021\/acsomega.3c10102"},{"key":"ref23\/cit23","doi-asserted-by":"publisher","DOI":"10.1007\/s11095-008-9801-2"},{"key":"ref24\/cit24","doi-asserted-by":"publisher","DOI":"10.1002\/advs.202507209"},{"key":"ref25\/cit25","doi-asserted-by":"publisher","DOI":"10.1016\/j.actbio.2022.07.053"},{"key":"ref26\/cit26","doi-asserted-by":"publisher","DOI":"10.3390\/polym14020248"},{"key":"ref27\/cit27","doi-asserted-by":"publisher","DOI":"10.3390\/ijms23084118"},{"key":"ref28\/cit28","doi-asserted-by":"publisher","DOI":"10.1016\/j.jconrel.2021.01.009"},{"key":"ref29\/cit29","doi-asserted-by":"publisher","DOI":"10.3390\/jfb16100381"},{"key":"ref30\/cit30","doi-asserted-by":"publisher","DOI":"10.1021\/acs.biomac.4c00690"},{"key":"ref31\/cit31","doi-asserted-by":"publisher","DOI":"10.1002\/adma.200501612"},{"key":"ref32\/cit32","doi-asserted-by":"publisher","DOI":"10.1002\/btm2.10680"},{"key":"ref33\/cit33","doi-asserted-by":"publisher","DOI":"10.1016\/S0142-9612(00)00258-1"},{"key":"ref34\/cit34","doi-asserted-by":"publisher","DOI":"10.1016\/S0168-3659(99)00027-9"},{"key":"ref35\/cit35","doi-asserted-by":"publisher","DOI":"10.1126\/science.252.5009.1164"},{"key":"ref36\/cit36","doi-asserted-by":"publisher","DOI":"10.1002\/adhm.202300105"},{"key":"ref37\/cit37","doi-asserted-by":"publisher","DOI":"10.1038\/s41563-023-01472-w"},{"key":"ref38\/cit38","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijpharm.2024.123801"},{"key":"ref39\/cit39","doi-asserted-by":"publisher","DOI":"10.1016\/j.jconrel.2014.03.052"},{"key":"ref40\/cit40","doi-asserted-by":"publisher","DOI":"10.1039\/C4RA13581D"},{"key":"ref41\/cit41","doi-asserted-by":"publisher","DOI":"10.1016\/j.actbio.2018.04.010"},{"key":"ref42\/cit42","doi-asserted-by":"publisher","DOI":"10.1002\/anie.200801951"},{"key":"ref43\/cit43","doi-asserted-by":"publisher","DOI":"10.1021\/ma900316t"},{"key":"ref44\/cit44","doi-asserted-by":"publisher","DOI":"10.1021\/ma300991p"},{"key":"ref45\/cit45","doi-asserted-by":"publisher","DOI":"10.1002\/pol.1984.170221134"},{"key":"ref46\/cit46","doi-asserted-by":"publisher","DOI":"10.1016\/0923-1137(92)90026-X"},{"key":"ref47\/cit47","doi-asserted-by":"publisher","DOI":"10.1021\/ma9517310"},{"key":"ref48\/cit48","doi-asserted-by":"publisher","DOI":"10.1002\/marc.202200420"},{"key":"ref49\/cit49","doi-asserted-by":"publisher","DOI":"10.1021\/acs.macromol.6b01999"},{"key":"ref50\/cit50","doi-asserted-by":"publisher","DOI":"10.1021\/acs.biomac.4c00181"},{"key":"ref51\/cit51","doi-asserted-by":"publisher","DOI":"10.1039\/c1py00320h"},{"key":"ref52\/cit52","doi-asserted-by":"publisher","DOI":"10.1016\/j.jconrel.2010.07.112"},{"key":"ref53\/cit53","doi-asserted-by":"publisher","DOI":"10.1002\/adma.200701028"},{"key":"ref54\/cit54","doi-asserted-by":"publisher","DOI":"10.1039\/C1PY00314C"},{"key":"ref55\/cit55","doi-asserted-by":"publisher","DOI":"10.1002\/pola.28664"},{"key":"ref56\/cit56","doi-asserted-by":"publisher","DOI":"10.1016\/j.eurpolymj.2014.11.025"},{"key":"ref57\/cit57","doi-asserted-by":"publisher","DOI":"10.1016\/j.eurpolymj.2014.11.025"},{"key":"ref58\/cit58","doi-asserted-by":"publisher","DOI":"10.1063\/1.1695690"},{"key":"ref59\/cit59","doi-asserted-by":"publisher","DOI":"10.1021\/acsnano.4c08922"}],"container-title":["Biomacromolecules"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acs.biomac.6c00138","content-type":"application\/pdf","content-version":"vor","intended-application":"unspecified"},{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acs.biomac.6c00138","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,6,8]],"date-time":"2026-06-08T08:11:59Z","timestamp":1780906319000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/acs.biomac.6c00138"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,5,14]]},"references-count":59,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2026,6,8]]}},"alternative-id":["10.1021\/acs.biomac.6c00138"],"URL":"https:\/\/doi.org\/10.1021\/acs.biomac.6c00138","relation":{},"ISSN":["1525-7797","1526-4602"],"issn-type":[{"value":"1525-7797","type":"print"},{"value":"1526-4602","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,5,14]]}}}