{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,28]],"date-time":"2026-09-28T19:44:21Z","timestamp":1790624661693,"version":"4.1.0"},"reference-count":62,"publisher":"American Chemical Society (ACS)","issue":"11","funder":[{"DOI":"10.13039\/501100003725","name":"National Research Foundation of Korea","doi-asserted-by":"publisher","award":["2017M3A7B8061942"],"award-info":[{"award-number":["2017M3A7B8061942"]}],"id":[{"id":"10.13039\/501100003725","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003725","name":"National Research Foundation of Korea","doi-asserted-by":"publisher","award":["2017R1C1B1003665"],"award-info":[{"award-number":["2017R1C1B1003665"]}],"id":[{"id":"10.13039\/501100003725","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Biomacromolecules"],"published-print":{"date-parts":[[2018,11,12]]},"DOI":"10.1021\/acs.biomac.8b01013","type":"journal-article","created":{"date-parts":[[2018,9,19]],"date-time":"2018-09-19T21:57:18Z","timestamp":1537394238000},"page":"4239-4249","source":"Crossref","is-referenced-by-count":51,"title":["Enhanced Skull Bone Regeneration by Sustained Release of BMP-2 in Interpenetrating Composite Hydrogels"],"prefix":"10.1021","volume":"19","author":[{"given":"Sungjun","family":"Kim","sequence":"first","affiliation":[{"name":"Division of Bioengineering, College of Life Sciences and Bioengineering, Incheon National University, Incheon, 22012 Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Junhyung","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Veterinary Surgery, College of Veterinary Medicine and Institute of Veterinary Science, Kangwon National University, Chuncheon 24341, Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mani","family":"Gajendiran","sequence":"additional","affiliation":[{"name":"Division of Bioengineering, College of Life Sciences and Bioengineering, Incheon National University, Incheon, 22012 Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Minhyuk","family":"Yoon","sequence":"additional","affiliation":[{"name":"Division of Bioengineering, College of Life Sciences and Bioengineering, Incheon National University, Incheon, 22012 Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mintai P.","family":"Hwang","sequence":"additional","affiliation":[{"name":"Meinig School of Biomedical Engineering, Cornell University, Ithaca, New York 14850, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yadong","family":"Wang","sequence":"additional","affiliation":[{"name":"Meinig School of Biomedical Engineering, Cornell University, Ithaca, New York 14850, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Byung-Jae","family":"Kang","sequence":"additional","affiliation":[{"name":"Department of Veterinary Surgery, College of Veterinary Medicine and Institute of Veterinary Science, Kangwon National University, Chuncheon 24341, Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3678-2078","authenticated-orcid":true,"given":"Kyobum","family":"Kim","sequence":"additional","affiliation":[{"name":"Division of Bioengineering, College of Life Sciences and Bioengineering, Incheon National University, Incheon, 22012 Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2018,9,19]]},"reference":[{"key":"ref1\/cit1","doi-asserted-by":"publisher","DOI":"10.1097\/00003086-198604000-00036"},{"key":"ref2\/cit2","doi-asserted-by":"publisher","DOI":"10.1097\/01.SCS.0000157311.85161.E8"},{"key":"ref3\/cit3","doi-asserted-by":"publisher","DOI":"10.3171\/2013.6.JNS1360"},{"key":"ref4\/cit4","doi-asserted-by":"publisher","DOI":"10.1007\/s00381-012-1776-y"},{"key":"ref5\/cit5","doi-asserted-by":"publisher","DOI":"10.1302\/0301-620X.63B3.7263759"},{"key":"ref6\/cit6","doi-asserted-by":"publisher","DOI":"10.1016\/j.msec.2017.12.023"},{"key":"ref7\/cit7","doi-asserted-by":"publisher","DOI":"10.1039\/C7BM00869D"},{"key":"ref8\/cit8","doi-asserted-by":"publisher","DOI":"10.1038\/nmat4407"},{"key":"ref9\/cit9","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2011.08.047"},{"key":"ref10\/cit10","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2007.02.023"},{"key":"ref11\/cit11","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M511039200"},{"key":"ref12\/cit12","doi-asserted-by":"publisher","DOI":"10.1016\/S0378-5173(99)00128-3"},{"key":"ref13\/cit13","doi-asserted-by":"publisher","DOI":"10.1089\/ten.teb.2015.0357"},{"key":"ref14\/cit14","doi-asserted-by":"publisher","DOI":"10.1089\/ten.tea.2013.0442"},{"key":"ref15\/cit15","doi-asserted-by":"publisher","DOI":"10.1163\/156856201744461"},{"key":"ref16\/cit16","doi-asserted-by":"publisher","DOI":"10.1038\/srep04706"},{"key":"ref17\/cit17","doi-asserted-by":"publisher","DOI":"10.1163\/092050611X587547"},{"key":"ref18\/cit18","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2011.09.031"},{"key":"ref19\/cit19","doi-asserted-by":"publisher","DOI":"10.1089\/ten.teb.2016.0442"},{"key":"ref20\/cit20","doi-asserted-by":"publisher","DOI":"10.1002\/jbm.a.10106"},{"key":"ref21\/cit21","doi-asserted-by":"publisher","DOI":"10.1186\/1559-4106-8-36"},{"key":"ref22\/cit22","doi-asserted-by":"publisher","DOI":"10.1002\/mabi.201600479"},{"key":"ref23\/cit23","doi-asserted-by":"publisher","DOI":"10.1155\/2012\/601549"},{"key":"ref24\/cit24","doi-asserted-by":"publisher","DOI":"10.1007\/s40005-017-0382-0"},{"key":"ref25\/cit25","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2014.07.006"},{"key":"ref26\/cit26","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2017.01.036"},{"key":"ref27\/cit27","doi-asserted-by":"publisher","DOI":"10.1016\/j.progpolymsci.2016.05.004"},{"key":"ref28\/cit28","doi-asserted-by":"publisher","DOI":"10.5966\/sctm.2013-0027"},{"key":"ref29\/cit29","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2013.08.082"},{"key":"ref30\/cit30","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2015.08.050"},{"key":"ref31\/cit31","doi-asserted-by":"publisher","DOI":"10.1016\/j.actbio.2009.07.041"},{"key":"ref32\/cit32","doi-asserted-by":"publisher","DOI":"10.1016\/j.actbio.2010.02.046"},{"key":"ref33\/cit33","doi-asserted-by":"publisher","DOI":"10.1016\/j.jconrel.2005.09.023"},{"key":"ref34\/cit34","doi-asserted-by":"publisher","DOI":"10.1016\/j.jconrel.2013.03.013"},{"key":"ref35\/cit35","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1110121108"},{"key":"ref36\/cit36","doi-asserted-by":"publisher","DOI":"10.1016\/j.jconrel.2012.11.004"},{"key":"ref37\/cit37","doi-asserted-by":"publisher","DOI":"10.1016\/j.actbio.2014.09.037"},{"key":"ref38\/cit38","doi-asserted-by":"publisher","DOI":"10.1021\/acsbiomaterials.5b00077"},{"key":"ref39\/cit39","doi-asserted-by":"publisher","DOI":"10.1111\/wrr.12319"},{"key":"ref40\/cit40","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2012.11.019"},{"key":"ref41\/cit41","doi-asserted-by":"publisher","DOI":"10.1021\/acs.biomac.6b00398"},{"key":"ref42\/cit42","doi-asserted-by":"publisher","DOI":"10.1016\/j.jconrel.2014.04.007"},{"key":"ref43\/cit43","doi-asserted-by":"publisher","DOI":"10.5966\/sctm.2015-0115"},{"key":"ref44\/cit44","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcis.2018.07.062"},{"key":"ref45\/cit45","doi-asserted-by":"publisher","DOI":"10.1021\/acsami.7b19022"},{"key":"ref46\/cit46","doi-asserted-by":"publisher","DOI":"10.1002\/btpr.728"},{"key":"ref47\/cit47","doi-asserted-by":"publisher","DOI":"10.1016\/j.jconrel.2010.11.025"},{"key":"ref48\/cit48","doi-asserted-by":"publisher","DOI":"10.1016\/j.actbio.2008.04.002"},{"key":"ref49\/cit49","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2007.10.029"},{"key":"ref50\/cit50","doi-asserted-by":"publisher","DOI":"10.1007\/s10439-016-1582-x"},{"key":"ref51\/cit51","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2011.01.016"},{"key":"ref52\/cit52","doi-asserted-by":"publisher","DOI":"10.1016\/j.bone.2008.06.019"},{"key":"ref53\/cit53","doi-asserted-by":"publisher","DOI":"10.1038\/nprot.2012.113"},{"key":"ref54\/cit54","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2010.01.075"},{"key":"ref55\/cit55","doi-asserted-by":"publisher","DOI":"10.3390\/ma9100854"},{"key":"ref56\/cit56","doi-asserted-by":"publisher","DOI":"10.1021\/am501391z"},{"key":"ref57\/cit57","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbrc.2016.07.049"},{"key":"ref58\/cit58","doi-asserted-by":"publisher","DOI":"10.1016\/j.jconrel.2014.04.014"},{"key":"ref59\/cit59","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbapap.2012.07.002"},{"key":"ref60\/cit60","doi-asserted-by":"publisher","DOI":"10.1111\/j.1432-1033.1996.0295n.x"},{"key":"ref61\/cit61","doi-asserted-by":"publisher","DOI":"10.1002\/jbmr.3417"},{"key":"ref62\/cit62","doi-asserted-by":"publisher","DOI":"10.1016\/j.metabol.2018.02.001"}],"container-title":["Biomacromolecules"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acs.biomac.8b01013","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,4,18]],"date-time":"2023-04-18T01:47:52Z","timestamp":1681782472000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/acs.biomac.8b01013"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,9,19]]},"references-count":62,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2018,11,12]]}},"alternative-id":["10.1021\/acs.biomac.8b01013"],"URL":"https:\/\/doi.org\/10.1021\/acs.biomac.8b01013","relation":{},"ISSN":["1525-7797","1526-4602"],"issn-type":[{"value":"1525-7797","type":"print"},{"value":"1526-4602","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,9,19]]}}}